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Volumn 145, Issue 1-3, 2008, Pages 42-48

Signal transduction for formation/release of interleukin-8 caused by a PAR2-activating peptide in human lung epithelial cells

Author keywords

EGF receptor; ERK; JNK; MAP kinase; Proteinase activated receptor 2; Tyrosine kinase

Indexed keywords

EPIDERMAL GROWTH FACTOR RECEPTOR KINASE; INTERLEUKIN 8; LEUCYLSERYLISOLEUCYLGLYCYCLARGYLLEUCINAMIDE; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE P38; PROSTAGLANDIN E2; PROSTAGLANDIN SYNTHASE; PROTEIN KINASE C; PROTEINASE ACTIVATED RECEPTOR 2; SERYLLEUCYLISOLEUCYLGLYCYLARGINYLLEUCINAMIDE; STRESS ACTIVATED PROTEIN KINASE; UNCLASSIFIED DRUG;

EID: 37349071522     PISSN: 01670115     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.regpep.2007.08.002     Document Type: Article
Times cited : (18)

References (32)
  • 2
    • 0031744875 scopus 로고    scopus 로고
    • Proteinase-activated receptors: novel mechanisms of signaling by serine proteases
    • Dery O., Corvera C.U., Steinhoff M., and Bunnett N.W. Proteinase-activated receptors: novel mechanisms of signaling by serine proteases. Am J Physiol 274 (1998) C1429-C1452
    • (1998) Am J Physiol , vol.274
    • Dery, O.1    Corvera, C.U.2    Steinhoff, M.3    Bunnett, N.W.4
  • 3
    • 0033168827 scopus 로고    scopus 로고
    • Protease-activated receptors: PAR4 and counting: how long is the course?
    • Hollenberg M.D. Protease-activated receptors: PAR4 and counting: how long is the course?. Trends Pharmacol Sci 20 (1999) 271-273
    • (1999) Trends Pharmacol Sci , vol.20 , pp. 271-273
    • Hollenberg, M.D.1
  • 4
    • 0034085870 scopus 로고    scopus 로고
    • Protease-activated receptor (PAR), a novel family of G protein-coupled seven trans-membrane domain receptors: activation mechanisms and physiological roles
    • Kawabata A., and Kuroda R. Protease-activated receptor (PAR), a novel family of G protein-coupled seven trans-membrane domain receptors: activation mechanisms and physiological roles. Jpn J Pharmacol 82 (2000) 171-174
    • (2000) Jpn J Pharmacol , vol.82 , pp. 171-174
    • Kawabata, A.1    Kuroda, R.2
  • 5
    • 0026035523 scopus 로고
    • Molecular cloning of a functional thrombin receptor reveals a novel proteolytic mechanism of receptor activation
    • Vu T.K., Hung D.T., Wheaton V.I., and Coughlin S.R. Molecular cloning of a functional thrombin receptor reveals a novel proteolytic mechanism of receptor activation. Cell 64 (1991) 1057-1068
    • (1991) Cell , vol.64 , pp. 1057-1068
    • Vu, T.K.1    Hung, D.T.2    Wheaton, V.I.3    Coughlin, S.R.4
  • 7
    • 0034624973 scopus 로고    scopus 로고
    • Tissue factor- and factor X-dependent activation of protease-activated receptor 2 by factor VIIa
    • Camerer E., Huang W., and Coughlin S.R. Tissue factor- and factor X-dependent activation of protease-activated receptor 2 by factor VIIa. Proc Natl Acad Sci U S A 97 (2000) 5255-5260
    • (2000) Proc Natl Acad Sci U S A , vol.97 , pp. 5255-5260
    • Camerer, E.1    Huang, W.2    Coughlin, S.R.3
  • 9
    • 0035378213 scopus 로고    scopus 로고
    • Pharmacological dissection of vascular effects caused by activation of protease-activated receptors 1 and 2 in anesthetized rats
    • Cicala C., Morello S., Santagada V., Caliendo G., Sorrentino L., and Cirino G. Pharmacological dissection of vascular effects caused by activation of protease-activated receptors 1 and 2 in anesthetized rats. FASEB J 15 (2001) 1433-1435
    • (2001) FASEB J , vol.15 , pp. 1433-1435
    • Cicala, C.1    Morello, S.2    Santagada, V.3    Caliendo, G.4    Sorrentino, L.5    Cirino, G.6
  • 10
    • 14644417853 scopus 로고    scopus 로고
    • Physiology and pathophysiology of proteinase-activated receptors (PARs): PARs in the respiratory system: cellular signaling and physiological/pathological roles
    • Kawabata A., and Kawao N. Physiology and pathophysiology of proteinase-activated receptors (PARs): PARs in the respiratory system: cellular signaling and physiological/pathological roles. J Pharmacol Sci 97 (2005) 20-24
    • (2005) J Pharmacol Sci , vol.97 , pp. 20-24
    • Kawabata, A.1    Kawao, N.2
  • 11
    • 0035953151 scopus 로고    scopus 로고
    • Peripheral PAR-2 triggers thermal hyperalgesia and nociceptive responses in rats
    • Kawabata A., Kawao N., Kuroda R., Tanaka A., Itoh H., and Nishikawa H. Peripheral PAR-2 triggers thermal hyperalgesia and nociceptive responses in rats. NeuroReport 12 (2001) 715-719
    • (2001) NeuroReport , vol.12 , pp. 715-719
    • Kawabata, A.1    Kawao, N.2    Kuroda, R.3    Tanaka, A.4    Itoh, H.5    Nishikawa, H.6
  • 13
    • 4644282618 scopus 로고    scopus 로고
    • Proteinase-activated receptor-2-mediated relaxation in mouse tracheal and bronchial smooth muscle: signal transduction mechanisms and distinct agonist sensitivity
    • Kawabata A., Kubo S., Ishiki T., Kawao N., Sekiguchi F., Kuroda R., Hollenberg M.D., Kanke T., and Saito N. Proteinase-activated receptor-2-mediated relaxation in mouse tracheal and bronchial smooth muscle: signal transduction mechanisms and distinct agonist sensitivity. J Pharmacol Exp Ther 311 (2004) 402-410
    • (2004) J Pharmacol Exp Ther , vol.311 , pp. 402-410
    • Kawabata, A.1    Kubo, S.2    Ishiki, T.3    Kawao, N.4    Sekiguchi, F.5    Kuroda, R.6    Hollenberg, M.D.7    Kanke, T.8    Saito, N.9
  • 14
    • 1342345222 scopus 로고    scopus 로고
    • Distinct roles for protease-activated receptors 1 and 2 in vasomotor modulation in rat superior mesenteric artery
    • Kawabata A., Kubo S., Nakaya Y., Ishiki T., Kuroda R., Sekiguchi F., Kawao N., and Nishikawa H. Distinct roles for protease-activated receptors 1 and 2 in vasomotor modulation in rat superior mesenteric artery. Cardiovasc Res 61 (2004) 683-692
    • (2004) Cardiovasc Res , vol.61 , pp. 683-692
    • Kawabata, A.1    Kubo, S.2    Nakaya, Y.3    Ishiki, T.4    Kuroda, R.5    Sekiguchi, F.6    Kawao, N.7    Nishikawa, H.8
  • 15
    • 1642279517 scopus 로고    scopus 로고
    • Protease-activated receptors: contribution to physiology and disease
    • Ossovskaya V.S., and Bunnett N.W. Protease-activated receptors: contribution to physiology and disease. Physiol Rev 84 (2004) 579-621
    • (2004) Physiol Rev , vol.84 , pp. 579-621
    • Ossovskaya, V.S.1    Bunnett, N.W.2
  • 17
    • 21044432260 scopus 로고    scopus 로고
    • Development of agonists/antagonists for protease-activated receptors (PARs) and the possible therapeutic application to gastrointestinal diseases
    • Sekiguchi F. Development of agonists/antagonists for protease-activated receptors (PARs) and the possible therapeutic application to gastrointestinal diseases. Yakugaku Zasshi 125 (2005) 491-498
    • (2005) Yakugaku Zasshi , vol.125 , pp. 491-498
    • Sekiguchi, F.1
  • 18
    • 0035081839 scopus 로고    scopus 로고
    • Protective effect of a PAR2-activating peptide on histamine-induced bronchoconstriction in guinea-pig
    • Cicala C., Spina D., Keir S.D., Severino B., Meli R., Page C.P., and Cirino G. Protective effect of a PAR2-activating peptide on histamine-induced bronchoconstriction in guinea-pig. Br J Pharmacol 132 (2001) 1229-1234
    • (2001) Br J Pharmacol , vol.132 , pp. 1229-1234
    • Cicala, C.1    Spina, D.2    Keir, S.D.3    Severino, B.4    Meli, R.5    Page, C.P.6    Cirino, G.7
  • 19
    • 0036014824 scopus 로고    scopus 로고
    • Protease-activated receptor-2 activating peptide SLIGRL inhibits bacterial lipopolysaccharide-induced recruitment of polymorphonuclear leukocytes into the airways of mice
    • Moffatt J.D., Jeffrey K.L., and Cocks T.M. Protease-activated receptor-2 activating peptide SLIGRL inhibits bacterial lipopolysaccharide-induced recruitment of polymorphonuclear leukocytes into the airways of mice. Am J Respir Cell Mol Biol 26 (2002) 680-684
    • (2002) Am J Respir Cell Mol Biol , vol.26 , pp. 680-684
    • Moffatt, J.D.1    Jeffrey, K.L.2    Cocks, T.M.3
  • 20
    • 0035146812 scopus 로고    scopus 로고
    • Role of PGE(2) in protease-activated receptor-1,-2 and-4 mediated relaxation in the mouse isolated trachea
    • Lan R.S., Knight D.A., Stewart G.A., and Henry P.J. Role of PGE(2) in protease-activated receptor-1,-2 and-4 mediated relaxation in the mouse isolated trachea. Br J Pharmacol 132 (2001) 93-100
    • (2001) Br J Pharmacol , vol.132 , pp. 93-100
    • Lan, R.S.1    Knight, D.A.2    Stewart, G.A.3    Henry, P.J.4
  • 21
    • 0036533649 scopus 로고    scopus 로고
    • Activation of protease-activated receptor (PAR)-1, PAR-2, and PAR-4 stimulates IL-6, IL-8, and prostaglandin E2 release from human respiratory epithelial cells
    • Asokananthan N., Graham P.T., Fink J., Knight D.A., Bakker A.J., McWilliam A.S., Thompson P.J., and Stewart G.A. Activation of protease-activated receptor (PAR)-1, PAR-2, and PAR-4 stimulates IL-6, IL-8, and prostaglandin E2 release from human respiratory epithelial cells. J Immunol 168 (2002) 3577-3585
    • (2002) J Immunol , vol.168 , pp. 3577-3585
    • Asokananthan, N.1    Graham, P.T.2    Fink, J.3    Knight, D.A.4    Bakker, A.J.5    McWilliam, A.S.6    Thompson, P.J.7    Stewart, G.A.8
  • 22
    • 0035879347 scopus 로고    scopus 로고
    • Interaction of mite allergens Der p3 and Der p9 with protease-activated receptor-2 expressed by lung epithelial cells
    • Sun G., Stacey M.A., Schmidt M., Mori L., and Mattoli S. Interaction of mite allergens Der p3 and Der p9 with protease-activated receptor-2 expressed by lung epithelial cells. J Immunol 167 (2001) 1014-1021
    • (2001) J Immunol , vol.167 , pp. 1014-1021
    • Sun, G.1    Stacey, M.A.2    Schmidt, M.3    Mori, L.4    Mattoli, S.5
  • 23
    • 0035042995 scopus 로고    scopus 로고
    • Airway epithelial cells release eosinophil survival-promoting factors (GM-CSF) after stimulation of proteinase-activated receptor 2
    • Vliagoftis H., Befus A.D., Hollenberg M.D., and Moqbel R. Airway epithelial cells release eosinophil survival-promoting factors (GM-CSF) after stimulation of proteinase-activated receptor 2. J Allergy Clin Immunol 107 (2001) 679-685
    • (2001) J Allergy Clin Immunol , vol.107 , pp. 679-685
    • Vliagoftis, H.1    Befus, A.D.2    Hollenberg, M.D.3    Moqbel, R.4
  • 25
    • 0037108373 scopus 로고    scopus 로고
    • House dust mite allergens induce proinflammatory cytokines from respiratory epithelial cells: the cysteine protease allergen, Der p 1, activates protease-activated receptor (PAR)-2 and inactivates PAR-1
    • Asokananthan N., Graham P.T., Stewart D.J., Bakker A.J., Eidne K.A., Thompson P.J., and Stewart G.A. House dust mite allergens induce proinflammatory cytokines from respiratory epithelial cells: the cysteine protease allergen, Der p 1, activates protease-activated receptor (PAR)-2 and inactivates PAR-1. J Immunol 169 (2002) 4572-4578
    • (2002) J Immunol , vol.169 , pp. 4572-4578
    • Asokananthan, N.1    Graham, P.T.2    Stewart, D.J.3    Bakker, A.J.4    Eidne, K.A.5    Thompson, P.J.6    Stewart, G.A.7
  • 26
    • 33745074367 scopus 로고    scopus 로고
    • House dust mite major allergens Der p 1 and Der p 5 activate human airway-derived epithelial cells by protease-dependent and protease-independent mechanisms
    • Kauffman H.F., Tamm M., Timmerman J.A., and Borger P. House dust mite major allergens Der p 1 and Der p 5 activate human airway-derived epithelial cells by protease-dependent and protease-independent mechanisms. Clin Mol Allergy 4 (2006) 5
    • (2006) Clin Mol Allergy , vol.4 , pp. 5
    • Kauffman, H.F.1    Tamm, M.2    Timmerman, J.A.3    Borger, P.4
  • 27
    • 33646368158 scopus 로고    scopus 로고
    • The house dust mite allergen Der p 1, unlike Der p 3, stimulates the expression of interleukin-8 in human airway epithelial cells via a proteinase-activated receptor-2-independent mechanism
    • Adam E., Hansen K.K., Astudillo O.F., Coulon L., Bex F., Duhant X., Jaumotte E., Hollenberg M.D., and Jacquet A. The house dust mite allergen Der p 1, unlike Der p 3, stimulates the expression of interleukin-8 in human airway epithelial cells via a proteinase-activated receptor-2-independent mechanism. J Biol Chem 281 (2006) 6910-6923
    • (2006) J Biol Chem , vol.281 , pp. 6910-6923
    • Adam, E.1    Hansen, K.K.2    Astudillo, O.F.3    Coulon, L.4    Bex, F.5    Duhant, X.6    Jaumotte, E.7    Hollenberg, M.D.8    Jacquet, A.9
  • 29
    • 33846316422 scopus 로고    scopus 로고
    • Proteinase-activated receptor-1 and -2 induce the release of chemokine GRO/CINC-1 from rat astrocytes via differential activation of JNK isoforms, evoking multiple protective pathways in brain
    • Wang Y., Luo W., and Reiser G. Proteinase-activated receptor-1 and -2 induce the release of chemokine GRO/CINC-1 from rat astrocytes via differential activation of JNK isoforms, evoking multiple protective pathways in brain. Biochem J 401 (2007) 65-78
    • (2007) Biochem J , vol.401 , pp. 65-78
    • Wang, Y.1    Luo, W.2    Reiser, G.3
  • 30
    • 0030947907 scopus 로고    scopus 로고
    • Endothelial cell thrombin receptors and PAR-2. Two protease-activated receptors located in a single cellular environment
    • Molino M., Woolkalis M.J., Reavey-Cantwell J., Pratico D., Andrade-Gordon P., Barnathan E.S., and Brass L.F. Endothelial cell thrombin receptors and PAR-2. Two protease-activated receptors located in a single cellular environment. J Biol Chem 272 (1997) 11133-11141
    • (1997) J Biol Chem , vol.272 , pp. 11133-11141
    • Molino, M.1    Woolkalis, M.J.2    Reavey-Cantwell, J.3    Pratico, D.4    Andrade-Gordon, P.5    Barnathan, E.S.6    Brass, L.F.7
  • 32
    • 9844231500 scopus 로고    scopus 로고
    • Endogenous trypsin receptors in Xenopus oocytes: linkage to internal calcium stores
    • Schultheiss M., Neumcke B., and Richter H.P. Endogenous trypsin receptors in Xenopus oocytes: linkage to internal calcium stores. Cell Mol Life Sci 53 (1997) 842-849
    • (1997) Cell Mol Life Sci , vol.53 , pp. 842-849
    • Schultheiss, M.1    Neumcke, B.2    Richter, H.P.3


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