-
2
-
-
33646093028
-
Polymorphism and ultrastructural organization of prion protein amyloid fibrils: An insight from high resolution atomic force microscopy
-
Anderson, M., O. V. Bocharova, N. Makarava, L. Breydo, V. V. Salnikov, and I. V. Baskakov. 2006. Polymorphism and ultrastructural organization of prion protein amyloid fibrils: an insight from high resolution atomic force microscopy. J. Mol. Biol. 358:580-596.
-
(2006)
J. Mol. Biol
, vol.358
, pp. 580-596
-
-
Anderson, M.1
Bocharova, O.V.2
Makarava, N.3
Breydo, L.4
Salnikov, V.V.5
Baskakov, I.V.6
-
3
-
-
56249149007
-
-
The Animals (Scientific Procedures) Act. 1986. Eliz. 2, chapter 14. Her Majesty's Stationery Office, London, United Kingdom.
-
The Animals (Scientific Procedures) Act. 1986. Eliz. 2, chapter 14. Her Majesty's Stationery Office, London, United Kingdom.
-
-
-
-
4
-
-
18744362997
-
BSE prions propagate as either variant CJD-like or sporadic CJD-like prion strains in transgenic mice expressing human prion protein
-
Asante, E. A., J. M. Linehan, M. Desbruslais, S. Joiner, I. Gowland, A. L. Wood, J. Welch, A. F. Hill, S. E. Lloyd, J. D. Wadsworth, and J. Collinge. 2002. BSE prions propagate as either variant CJD-like or sporadic CJD-like prion strains in transgenic mice expressing human prion protein. EMBO J. 21:6358-6366.
-
(2002)
EMBO J
, vol.21
, pp. 6358-6366
-
-
Asante, E.A.1
Linehan, J.M.2
Desbruslais, M.3
Joiner, S.4
Gowland, I.5
Wood, A.L.6
Welch, J.7
Hill, A.F.8
Lloyd, S.E.9
Wadsworth, J.D.10
Collinge, J.11
-
5
-
-
2642543167
-
Molecular analysis of the protease-resistant prion protein in scrapie and bovine spongiform encephalopathy transmitted to ovine transgenic and wild-type mice
-
Baron, T., C. Crozet, A. G. Biacabe, S. Philippe, J. Verchere, A. Bencsik, J. Y. Madec, D. Calavas, and J. Samarut. 2004. Molecular analysis of the protease-resistant prion protein in scrapie and bovine spongiform encephalopathy transmitted to ovine transgenic and wild-type mice. J. Virol. 78:6243-6251.
-
(2004)
J. Virol
, vol.78
, pp. 6243-6251
-
-
Baron, T.1
Crozet, C.2
Biacabe, A.G.3
Philippe, S.4
Verchere, J.5
Bencsik, A.6
Madec, J.Y.7
Calavas, D.8
Samarut, J.9
-
6
-
-
56249104262
-
-
Prion, NeuroPrion European Network of Excellence
-
Beck, K., R. Salis, S. Simonini, and J. Spiropoulos. 2007. Primary isolation of the scrapie agent in RIII mice: identification of sheep PrP genotype-associated profiles, abstr. P02.20. Prion 2007. NeuroPrion European Network of Excellence.
-
(2007)
Primary isolation of the scrapie agent in RIII mice: Identification of sheep PrP genotype-associated profiles, abstr
-
-
Beck, K.1
Salis, R.2
Simonini, S.3
Spiropoulos, J.4
-
7
-
-
33750454756
-
Isolation from cattle of a prion strain distinct from that causing bovine spongiform encephalopathy
-
Beringue, V., A. Bencsik, A. Le Dur, F. Reine, T. L. Lai, N. Chenais, G. Tilly, A. G. Biacabe, T. Baron, J. L. Vilotte, and H. Laude. 2006. Isolation from cattle of a prion strain distinct from that causing bovine spongiform encephalopathy. PLoS Pathog. 2:e112.
-
(2006)
PLoS Pathog
, vol.2
-
-
Beringue, V.1
Bencsik, A.2
Le Dur, A.3
Reine, F.4
Lai, T.L.5
Chenais, N.6
Tilly, G.7
Biacabe, A.G.8
Baron, T.9
Vilotte, J.L.10
Laude, H.11
-
8
-
-
0026583834
-
Biochemical and physical properties of the prion protein from two strains of the transmissible mink encephalopathy agent
-
Bessen, R. A., and R. F. Marsh. 1992. Biochemical and physical properties of the prion protein from two strains of the transmissible mink encephalopathy agent. J. Virol. 66:2096-2101.
-
(1992)
J. Virol
, vol.66
, pp. 2096-2101
-
-
Bessen, R.A.1
Marsh, R.F.2
-
9
-
-
0028043661
-
Distinct PrP properties suggest the molecular basis of strain variation in transmissible mink encephalopathy
-
Bessen, R. A., and R. F. Marsh. 1994. Distinct PrP properties suggest the molecular basis of strain variation in transmissible mink encephalopathy. J. Virol. 68:7859-7868.
-
(1994)
J. Virol
, vol.68
, pp. 7859-7868
-
-
Bessen, R.A.1
Marsh, R.F.2
-
10
-
-
8644260825
-
Transmission of prions from mule deer and elk with chronic wasting disease to transgenic mice expressing cervid PrP
-
Browning, S. R., G. L. Mason, T. Seward, M. Green, G. A. Eliason, C. Mathiason, M. W. Miller, E. S. Williams, E. Hoover, and G. C. Telling. 2004. Transmission of prions from mule deer and elk with chronic wasting disease to transgenic mice expressing cervid PrP. J. Virol. 78:13345-13350.
-
(2004)
J. Virol
, vol.78
, pp. 13345-13350
-
-
Browning, S.R.1
Mason, G.L.2
Seward, T.3
Green, M.4
Eliason, G.A.5
Mathiason, C.6
Miller, M.W.7
Williams, E.S.8
Hoover, E.9
Telling, G.C.10
-
11
-
-
0027740178
-
Scrapie strain variation and mutation
-
Bruce, M. E. 1993. Scrapie strain variation and mutation. Br. Med. Bull. 49:822-838.
-
(1993)
Br. Med. Bull
, vol.49
, pp. 822-838
-
-
Bruce, M.E.1
-
12
-
-
0141515178
-
TSE strain variation.
-
Bruce, M. E. 2003. TSE strain variation. Br. Med. Bull. 66:99-108.
-
(2003)
Br. Med. Bull
, vol.66
, pp. 99-108
-
-
Bruce, M.E.1
-
13
-
-
0036184403
-
Strain characterization of natural sheep scrapie and comparison with BSE
-
Bruce, M. E., A. Boyle, S. Cousens, I. McConnell, J. Foster, W. Goldmann, and H. Fraser. 2002. Strain characterization of natural sheep scrapie and comparison with BSE. J. Gen. Virol. 83:695-704.
-
(2002)
J. Gen. Virol
, vol.83
, pp. 695-704
-
-
Bruce, M.E.1
Boyle, A.2
Cousens, S.3
McConnell, I.4
Foster, J.5
Goldmann, W.6
Fraser, H.7
-
14
-
-
0025836628
-
Scrapie strain variation and its implications
-
Bruce, M. E., and H. Fraser. 1991. Scrapie strain variation and its implications. Curr. Top. Microbiol. Immunol. 172:125-138.
-
(1991)
Curr. Top. Microbiol. Immunol
, vol.172
, pp. 125-138
-
-
Bruce, M.E.1
Fraser, H.2
-
15
-
-
0037041420
-
Inherent toxicity of aggregates implies a common mechanism for protein misfolding diseases
-
Bucciantini, M., E. Giannoni, F. Chiti, F. Baroni, L. Formigli, J. Zurdo, N. Taddei, G. Ramponi, C. M. Dobson, and M. Stefani. 2002. Inherent toxicity of aggregates implies a common mechanism for protein misfolding diseases. Nature 416:507-511.
-
(2002)
Nature
, vol.416
, pp. 507-511
-
-
Bucciantini, M.1
Giannoni, E.2
Chiti, F.3
Baroni, F.4
Formigli, L.5
Zurdo, J.6
Taddei, N.7
Ramponi, G.8
Dobson, C.M.9
Stefani, M.10
-
16
-
-
0027319326
-
Mice devoid of PrP are resistant to scrapie
-
Bueler, H., A. Aguzzi, A. Sailer, R. A. Greiner, P. Autenried, M. Aguet, and C. Weissmann. 1993. Mice devoid of PrP are resistant to scrapie. Cell 73:1339-1347.
-
(1993)
Cell
, vol.73
, pp. 1339-1347
-
-
Bueler, H.1
Aguzzi, A.2
Sailer, A.3
Greiner, R.A.4
Autenried, P.5
Aguet, M.6
Weissmann, C.7
-
17
-
-
28644432876
-
Structural differences between allelic variants of the ovine prion protein revealed by molecular dynamics simulations
-
Bujdoso, R., D. F. Burke, and A. M. Thackray. 2005. Structural differences between allelic variants of the ovine prion protein revealed by molecular dynamics simulations. Proteins 61:840-849.
-
(2005)
Proteins
, vol.61
, pp. 840-849
-
-
Bujdoso, R.1
Burke, D.F.2
Thackray, A.M.3
-
18
-
-
28444450920
-
Detection of cattle-derived BSE prions using transgenic mice overexpressing bovine PrP(C)
-
Buschmann, A., E. Pfaff, K. Reifenberg, H. M. Muller, and M. H. Groschup. 2000. Detection of cattle-derived BSE prions using transgenic mice overexpressing bovine PrP(C). Arch. Virol. Suppl. 2000:75-86.
-
(2000)
Arch. Virol. Suppl
, vol.2000
, pp. 75-86
-
-
Buschmann, A.1
Pfaff, E.2
Reifenberg, K.3
Muller, H.M.4
Groschup, M.H.5
-
19
-
-
0032472239
-
BSE and prions: Uncertainties about the agent
-
Chesebro, B. 1998. BSE and prions: uncertainties about the agent. Science 279:42-43.
-
(1998)
Science
, vol.279
, pp. 42-43
-
-
Chesebro, B.1
-
20
-
-
0035168351
-
Prion diseases: What is the neurotoxic molecule?
-
Chiesa, R., and D. A. Harris. 2001. Prion diseases: what is the neurotoxic molecule? Neurobiol. Dis. 8:743-763.
-
(2001)
Neurobiol. Dis
, vol.8
, pp. 743-763
-
-
Chiesa, R.1
Harris, D.A.2
-
21
-
-
0038128629
-
Molecular distinction between pathogenic and infectious properties of the prion protein
-
Chiesa, R., P. Piccardo, E. Quaglio, B. Drisaldi, S. L. Si-Hoe, M. Takao, B. Ghetti, and D. A. Harris. 2003. Molecular distinction between pathogenic and infectious properties of the prion protein. J. Virol. 77:7611-7622.
-
(2003)
J. Virol
, vol.77
, pp. 7611-7622
-
-
Chiesa, R.1
Piccardo, P.2
Quaglio, E.3
Drisaldi, B.4
Si-Hoe, S.L.5
Takao, M.6
Ghetti, B.7
Harris, D.A.8
-
22
-
-
0033600407
-
Variant Creutzfeldt-Jakob disease
-
Collinge, J. 1999. Variant Creutzfeldt-Jakob disease. Lancet 354:317-323.
-
(1999)
Lancet
, vol.354
, pp. 317-323
-
-
Collinge, J.1
-
23
-
-
36049020231
-
A general model of prion strains and their pathogenicity
-
Collinge, J., and A. R. Clarke. 2007. A general model of prion strains and their pathogenicity. Science 318:930-936.
-
(2007)
Science
, vol.318
, pp. 930-936
-
-
Collinge, J.1
Clarke, A.R.2
-
24
-
-
0029160006
-
Transmission of fatal familial insomnia to laboratory animals
-
Collinge, J., M. S. Palmer, K. C. Sidle, I. Gowland, R. Medori, J. Ironside, and P. Lantos. 1995. Transmission of fatal familial insomnia to laboratory animals. Lancet 346:569-570.
-
(1995)
Lancet
, vol.346
, pp. 569-570
-
-
Collinge, J.1
Palmer, M.S.2
Sidle, K.C.3
Gowland, I.4
Medori, R.5
Ironside, J.6
Lantos, P.7
-
25
-
-
0029831213
-
Molecular analysis of prion strain variation and the aetiology of 'new variant' CJD
-
Collinge, J., K. C. Sidle, J. Meads, J. Ironside, and A. F. Hill. 1996. Molecular analysis of prion strain variation and the aetiology of 'new variant' CJD. Nature 383:685-690.
-
(1996)
Nature
, vol.383
, pp. 685-690
-
-
Collinge, J.1
Sidle, K.C.2
Meads, J.3
Ironside, J.4
Hill, A.F.5
-
26
-
-
33751399001
-
Transmission and characterization of bovine spongiform encephalopathy sources in two ovine transgenic mouse lines (TgOvPrP4 and TgOvPrP59)
-
Cordier, C., A. Bencsik, S. Philippe, D. Betemps, F. Ronzon, D. Calavas, C. Crozet, and T. Baron. 2006. Transmission and characterization of bovine spongiform encephalopathy sources in two ovine transgenic mouse lines (TgOvPrP4 and TgOvPrP59). J. Gen. Virol. 87:3763-3771.
-
(2006)
J. Gen. Virol
, vol.87
, pp. 3763-3771
-
-
Cordier, C.1
Bencsik, A.2
Philippe, S.3
Betemps, D.4
Ronzon, F.5
Calavas, D.6
Crozet, C.7
Baron, T.8
-
27
-
-
0035025625
-
Efficient transmission of two different sheep scrapie isolates in transgenic mice expressing the ovine PrP gene
-
Crozet, C., F. Flamant, A. Bencsik, D. Aubert, J. Samarut, and T. Baron. 2001. Efficient transmission of two different sheep scrapie isolates in transgenic mice expressing the ovine PrP gene. J. Virol. 75:5328-5334.
-
(2001)
J. Virol
, vol.75
, pp. 5328-5334
-
-
Crozet, C.1
Flamant, F.2
Bencsik, A.3
Aubert, D.4
Samarut, J.5
Baron, T.6
-
28
-
-
0015177637
-
Host-genotype and agent effects in scrapie incubation: Change in allelic interaction with different strains of agent
-
Dickinson, A. G., and V. M. Meikle. 1971. Host-genotype and agent effects in scrapie incubation: change in allelic interaction with different strains of agent. Mol. Gen. Genet. 112:73-79.
-
(1971)
Mol. Gen. Genet
, vol.112
, pp. 73-79
-
-
Dickinson, A.G.1
Meikle, V.M.2
-
29
-
-
0014305661
-
Identification of a gene which controls the incubation period of some strains of scrapie agent in mice
-
Dickinson, A. G., V. M. Meikle, and H. Fraser. 1968. Identification of a gene which controls the incubation period of some strains of scrapie agent in mice. J. Comp. Pathol. 78:293-299.
-
(1968)
J. Comp. Pathol
, vol.78
, pp. 293-299
-
-
Dickinson, A.G.1
Meikle, V.M.2
Fraser, H.3
-
30
-
-
3142683624
-
Insight into the PrPC→PrPSc conversion from the structures of antibody-bound ovine prion scrapie-susceptibility variants
-
Eghiaian, F., J. Grosclaude, S. Lesceu, P. Debey, B. Doublet, E. Treguer, H. Rezaei, and M. Knossow. 2004. Insight into the PrPC→PrPSc conversion from the structures of antibody-bound ovine prion scrapie-susceptibility variants. Proc. Natl. Acad. Sci. USA 101:10254- 10259.
-
(2004)
Proc. Natl. Acad. Sci. USA
, vol.101
, pp. 10254-10259
-
-
Eghiaian, F.1
Grosclaude, J.2
Lesceu, S.3
Debey, P.4
Doublet, B.5
Treguer, E.6
Rezaei, H.7
Knossow, M.8
-
31
-
-
33846103823
-
Sheep-passaged bovine spongiform encephalopathy agent exhibits altered pathobiological properties in bovine-PrP transgenic mice
-
Espinosa, J. C., O. Andreoletti, J. Castilla, M. E. Herva, M. Morales, E. Alamillo, F. D. San-Segundo, C. Lacroux, S. Lugan, F. J. Salguero, J. Langeveld, and J. M. Torres. 2007. Sheep-passaged bovine spongiform encephalopathy agent exhibits altered pathobiological properties in bovine-PrP transgenic mice. J. Virol. 81:835-843.
-
(2007)
J. Virol
, vol.81
, pp. 835-843
-
-
Espinosa, J.C.1
Andreoletti, O.2
Castilla, J.3
Herva, M.E.4
Morales, M.5
Alamillo, E.6
San-Segundo, F.D.7
Lacroux, C.8
Lugan, S.9
Salguero, F.J.10
Langeveld, J.11
Torres, J.M.12
-
33
-
-
0015550206
-
Scrapie in mice. Agent-strain differences in the distribution and intensity of grey matter vacuolation
-
Fraser, H., and A. G. Dickinson. 1973. Scrapie in mice. Agent-strain differences in the distribution and intensity of grey matter vacuolation. J. Comp. Pathol. 83:29-40.
-
(1973)
J. Comp. Pathol
, vol.83
, pp. 29-40
-
-
Fraser, H.1
Dickinson, A.G.2
-
34
-
-
0014308027
-
The sequential development of the brain lesion of scrapie in three strains of mice
-
Fraser, H., and A. G. Dickinson. 1968. The sequential development of the brain lesion of scrapie in three strains of mice. J. Comp. Pathol. 78:301-311.
-
(1968)
J. Comp. Pathol
, vol.78
, pp. 301-311
-
-
Fraser, H.1
Dickinson, A.G.2
-
35
-
-
0036376780
-
Effects of agent strain and host genotype on PrP accumulation in the brain of sheep naturally and experimentally affected with scrapie
-
Gonzalez, L., S. Martin, I. Begara-McGorum, N. Hunter, F. Houston, M. Simmons, and M. Jeffrey. 2002. Effects of agent strain and host genotype on PrP accumulation in the brain of sheep naturally and experimentally affected with scrapie. J. Comp. Pathol. 126:17-29.
-
(2002)
J. Comp. Pathol
, vol.126
, pp. 17-29
-
-
Gonzalez, L.1
Martin, S.2
Begara-McGorum, I.3
Hunter, N.4
Houston, F.5
Simmons, M.6
Jeffrey, M.7
-
36
-
-
14544306457
-
Primary isolation of the bovine spongiform encephalopathy agent in mice: Agent definition based on a review of 150 transmissions
-
Green, R. B., C. Horrocks, A. Wilkinson, S. A. C. Hawkins, and S. J. Ryder. 2005. Primary isolation of the bovine spongiform encephalopathy agent in mice: agent definition based on a review of 150 transmissions. J. Comp. Pathol. 132:117-131.
-
(2005)
J. Comp. Pathol
, vol.132
, pp. 117-131
-
-
Green, R.B.1
Horrocks, C.2
Wilkinson, A.3
Hawkins, S.A.C.4
Ryder, S.J.5
-
37
-
-
0034730170
-
Species-barrier-independent prion replication in apparently resistant species
-
Hill, A. F., S. Joiner, J. Linehan, M. Desbruslais, P. L. Lantos, and J. Collinge. 2000. Species-barrier-independent prion replication in apparently resistant species. Proc. Natl. Acad. Sci. USA 97:10248-10253.
-
(2000)
Proc. Natl. Acad. Sci. USA
, vol.97
, pp. 10248-10253
-
-
Hill, A.F.1
Joiner, S.2
Linehan, J.3
Desbruslais, M.4
Lantos, P.L.5
Collinge, J.6
-
38
-
-
0025681138
-
Spontaneous neurodegeneration in transgenic mice with mutant prion protein
-
Hsiao, K. K., M. Scott, D. Foster, D. F. Groth, S. J. DeArmond, and S. B. Prusiner. 1990. Spontaneous neurodegeneration in transgenic mice with mutant prion protein. Science 250:1587-1590.
-
(1990)
Science
, vol.250
, pp. 1587-1590
-
-
Hsiao, K.K.1
Scott, M.2
Foster, D.3
Groth, D.F.4
DeArmond, S.J.5
Prusiner, S.B.6
-
39
-
-
0023265523
-
Temporary and permanent modifications to a single strain of mouse scrapie on transmission to rats and hamsters
-
Kimberlin, R. H., S. Cole, and C. A. Walker. 1987. Temporary and permanent modifications to a single strain of mouse scrapie on transmission to rats and hamsters. J. Gen. Virol. 68:1875-1881.
-
(1987)
J. Gen. Virol
, vol.68
, pp. 1875-1881
-
-
Kimberlin, R.H.1
Cole, S.2
Walker, C.A.3
-
40
-
-
0017866857
-
Evidence that the transmission of one source of scrapie agent to hamsters involves separation of agent strains from a mixture
-
Kimberlin, R. H., and C. A. Walker. 1978. Evidence that the transmission of one source of scrapie agent to hamsters involves separation of agent strains from a mixture. J. Gen. Virol. 39:487-496.
-
(1978)
J. Gen. Virol
, vol.39
, pp. 487-496
-
-
Kimberlin, R.H.1
Walker, C.A.2
-
41
-
-
0024325787
-
The genomic identity of different strains of mouse scrapie is expressed in hamsters and preserved on reisolation in mice
-
Kimberlin, R. H., C. A. Walker, and H. Fraser. 1989. The genomic identity of different strains of mouse scrapie is expressed in hamsters and preserved on reisolation in mice. J. Gen. Virol. 70:2017-2025.
-
(1989)
J. Gen. Virol
, vol.70
, pp. 2017-2025
-
-
Kimberlin, R.H.1
Walker, C.A.2
Fraser, H.3
-
42
-
-
0030613755
-
Prion (PrPSc)-specific epitope defined by a monoclonal antibody
-
Korth, C., B. Stierli, P. Streit, M. Moser, O. Schaller, R. Fischer, W. Schulz-Schaeffer, H. Kretzschmar, A. Raeber, U. Braun, F. Ehrensperger, S. Hornemann, R. Glockshuber, R. Riek, M. Billeter, K. Wuthrich, and B. Oesch. 1997. Prion (PrPSc)-specific epitope defined by a monoclonal antibody. Nature 390:74-77.
-
(1997)
Nature
, vol.390
, pp. 74-77
-
-
Korth, C.1
Stierli, B.2
Streit, P.3
Moser, M.4
Schaller, O.5
Fischer, R.6
Schulz-Schaeffer, W.7
Kretzschmar, H.8
Raeber, A.9
Braun, U.10
Ehrensperger, F.11
Hornemann, S.12
Glockshuber, R.13
Riek, R.14
Billeter, M.15
Wuthrich, K.16
Oesch, B.17
-
43
-
-
0344030333
-
Transmission of the BSE agent to mice in the absence of detectable abnormal prion protein
-
Lasmezas, C. I., J. P. Deslys, O. Robain, A. Jaegly, V. Beringue, J. M. Peyrin, J. G. Fournier, J. J. Hauw, J. Rossier, and D. Dormont. 1997. Transmission of the BSE agent to mice in the absence of detectable abnormal prion protein. Science 275:402-405.
-
(1997)
Science
, vol.275
, pp. 402-405
-
-
Lasmezas, C.I.1
Deslys, J.P.2
Robain, O.3
Jaegly, A.4
Beringue, V.5
Peyrin, J.M.6
Fournier, J.G.7
Hauw, J.J.8
Rossier, J.9
Dormont, D.10
-
44
-
-
27644492381
-
A newly identified type of scrapie agent can naturally infect sheep with resistant PrP genotypes
-
Le Dur, A., V. Beringue, O. Andreoletti, F. Reine, T. L. Lai, T. Baron, B. Bratberg, J. L. Vilotte, P. Sarradin, S. L. Benestad, and H. Laude. 2005. A newly identified type of scrapie agent can naturally infect sheep with resistant PrP genotypes. Proc. Natl. Acad. Sci. USA 102:16031-16036.
-
(2005)
Proc. Natl. Acad. Sci. USA
, vol.102
, pp. 16031-16036
-
-
Le Dur, A.1
Beringue, V.2
Andreoletti, O.3
Reine, F.4
Lai, T.L.5
Baron, T.6
Bratberg, B.7
Vilotte, J.L.8
Sarradin, P.9
Benestad, S.L.10
Laude, H.11
-
45
-
-
34447639732
-
Continuum of prion protein structures enciphers a multitude of prion isolate-specified phenotypes
-
Legname, G., H. O. Nguyen, D. Peretz, F. E. Cohen, S. J. DeArmond, and S. B. Prusiner. 2006. Continuum of prion protein structures enciphers a multitude of prion isolate-specified phenotypes. Proc. Natl. Acad. Sci. USA 103:19105-19110.
-
(2006)
Proc. Natl. Acad. Sci. USA
, vol.103
, pp. 19105-19110
-
-
Legname, G.1
Nguyen, H.O.2
Peretz, D.3
Cohen, F.E.4
DeArmond, S.J.5
Prusiner, S.B.6
-
46
-
-
7044229895
-
Distribution of vascular amyloid in scrapie-affected sheep with different genotypes
-
Ligios, C., G. Dexter, J. Spiropoulos, C. Maestrale, A. Carta, and M. M. Simmons. 2004. Distribution of vascular amyloid in scrapie-affected sheep with different genotypes. J. Comp. Pathol. 131:271-276.
-
(2004)
J. Comp. Pathol
, vol.131
, pp. 271-276
-
-
Ligios, C.1
Dexter, G.2
Spiropoulos, J.3
Maestrale, C.4
Carta, A.5
Simmons, M.M.6
-
47
-
-
0242363656
-
Depleting neuronal PrP in prion infection prevents disease and reverses spongiosis
-
Mallucci, G., A. Dickinson, J. Linehan, P. C. Klohn, S. Brandner, and J. Collinge. 2003. Depleting neuronal PrP in prion infection prevents disease and reverses spongiosis. Science 302:871-874.
-
(2003)
Science
, vol.302
, pp. 871-874
-
-
Mallucci, G.1
Dickinson, A.2
Linehan, J.3
Klohn, P.C.4
Brandner, S.5
Collinge, J.6
-
48
-
-
33846538022
-
Targeting cellular prion protein reverses early cognitive deficits and neurophysiological dysfunction in prion-infected mice
-
Mallucci, G. R., M. D. White, M. Farmer, A. Dickinson, H. Khatun, A. D. Powell, S. Brandner, J. G. Jefferys, and J. Collinge. 2007. Targeting cellular prion protein reverses early cognitive deficits and neurophysiological dysfunction in prion-infected mice. Neuron 53:325-335.
-
(2007)
Neuron
, vol.53
, pp. 325-335
-
-
Mallucci, G.R.1
White, M.D.2
Farmer, M.3
Dickinson, A.4
Khatun, H.5
Powell, A.D.6
Brandner, S.7
Jefferys, J.G.8
Collinge, J.9
-
49
-
-
0028703452
-
PrP gene dosage determines the timing but not the final intensity or distribution of lesions in scrapie pathology
-
Manson, J. C., A. R. Clarke, P. A. McBride, I. McConnell, and J. Hope. 1994. PrP gene dosage determines the timing but not the final intensity or distribution of lesions in scrapie pathology. Neurodegeneration 3:331-340.
-
(1994)
Neurodegeneration
, vol.3
, pp. 331-340
-
-
Manson, J.C.1
Clarke, A.R.2
McBride, P.A.3
McConnell, I.4
Hope, J.5
-
50
-
-
0033485260
-
A single amino acid alteration (101L) introduced into murine PrP dramatically alters incubation time of transmissible spongiform encephalopathy
-
Manson, J. C., E. Jamieson, H. Baybutt, N. L. Tuzi, R. Barron, I. McConnell, R. Somerville, J. Ironside, R. Will, M. S. Sy, D. W. Melton, J. Hope, and C. Bostock. 1999. A single amino acid alteration (101L) introduced into murine PrP dramatically alters incubation time of transmissible spongiform encephalopathy. EMBO J. 18:6855-6864.
-
(1999)
EMBO J
, vol.18
, pp. 6855-6864
-
-
Manson, J.C.1
Jamieson, E.2
Baybutt, H.3
Tuzi, N.L.4
Barron, R.5
McConnell, I.6
Somerville, R.7
Ironside, J.8
Will, R.9
Sy, M.S.10
Melton, D.W.11
Hope, J.12
Bostock, C.13
-
51
-
-
0026690906
-
Fatal familial insomnia: A second kindred with mutation of prion protein gene at codon 178
-
Medori, R., P. Montagna, H. J. Tritschler, A. LeBlanc, P. Cortelli, P. Tinuper, E. Lugaresi, and P. Gambetti. 1992. Fatal familial insomnia: a second kindred with mutation of prion protein gene at codon 178. Neurology 42:669-670.
-
(1992)
Neurology
, vol.42
, pp. 669-670
-
-
Medori, R.1
Montagna, P.2
Tritschler, H.J.3
LeBlanc, A.4
Cortelli, P.5
Tinuper, P.6
Lugaresi, E.7
Gambetti, P.8
-
52
-
-
0028351904
-
Fatal familial insomnia and familial Creutzfeldt-Jakob disease: Different prion proteins determined by a DNA polymorphism
-
Monari, L., S. G. Chen, P. Brown, P. Parchi, R. B. Petersen, J. Mikol, F. Gray, P. Cortelli, P. Montagna, and B. Ghetti. 1994. Fatal familial insomnia and familial Creutzfeldt-Jakob disease: different prion proteins determined by a DNA polymorphism. Proc. Natl. Acad. Sci. USA 91:2839-2842.
-
(1994)
Proc. Natl. Acad. Sci. USA
, vol.91
, pp. 2839-2842
-
-
Monari, L.1
Chen, S.G.2
Brown, P.3
Parchi, P.4
Petersen, R.B.5
Mikol, J.6
Gray, F.7
Cortelli, P.8
Montagna, P.9
Ghetti, B.10
-
53
-
-
8944259890
-
Molecular basis of phenotypic variability in sporadic Creutzfeldt-Jakob disease
-
Parchi, P., R. Castellani, S. Capellari, B. Ghetti, K. Young, S. G. Chen, M. Farlow, D. W. Dickson, A. A. Sima, J. Q. Trojanowski, R. B. Petersen, and P. Gambetti. 1996. Molecular basis of phenotypic variability in sporadic Creutzfeldt-Jakob disease. Ann. Neurol. 39:767-778.
-
(1996)
Ann. Neurol
, vol.39
, pp. 767-778
-
-
Parchi, P.1
Castellani, R.2
Capellari, S.3
Ghetti, B.4
Young, K.5
Chen, S.G.6
Farlow, M.7
Dickson, D.W.8
Sima, A.A.9
Trojanowski, J.Q.10
Petersen, R.B.11
Gambetti, P.12
-
54
-
-
0035086136
-
Strain-specified relative conformational stability of the scrapie prion protein
-
Peretz, D., M. R. Scott, D. Groth, R. A. Williamson, D. R. Burton, F. E. Cohen, and S. B. Prusiner. 2001. Strain-specified relative conformational stability of the scrapie prion protein. Protein Sci. 10:854-863.
-
(2001)
Protein Sci
, vol.10
, pp. 854-863
-
-
Peretz, D.1
Scott, M.R.2
Groth, D.3
Williamson, R.A.4
Burton, D.R.5
Cohen, F.E.6
Prusiner, S.B.7
-
55
-
-
0037071874
-
A change in the conformation of prions accompanies the emergence of a new prion strain
-
Peretz, D., R. A. Williamson, G. Legname, Y. Matsunaga, J. Vergara, D. R. Burton, S. J. DeArmond, S. B. Prusiner, and M. R. Scott. 2002. A change in the conformation of prions accompanies the emergence of a new prion strain. Neuron 34:921-932.
-
(2002)
Neuron
, vol.34
, pp. 921-932
-
-
Peretz, D.1
Williamson, R.A.2
Legname, G.3
Matsunaga, Y.4
Vergara, J.5
Burton, D.R.6
DeArmond, S.J.7
Prusiner, S.B.8
Scott, M.R.9
-
56
-
-
0020321767
-
Novel proteinaceous infectious particles cause scrapie
-
Prusiner, S. B. 1982. Novel proteinaceous infectious particles cause scrapie. Science 216:136-144.
-
(1982)
Science
, vol.216
, pp. 136-144
-
-
Prusiner, S.B.1
-
57
-
-
0034790796
-
Long-term subclinical carrier state precedes scrapie replication and adaptation in a resistant species: Analogies to bovine spongiform encephalopathy and variant Creutzfeldt-Jakob disease in humans
-
Race, R., A. Raines, G. J. Raymond, B. Caughey, and B. Chesebro. 2001. Long-term subclinical carrier state precedes scrapie replication and adaptation in a resistant species: analogies to bovine spongiform encephalopathy and variant Creutzfeldt-Jakob disease in humans. J. Virol. 75:10106- 10112.
-
(2001)
J. Virol
, vol.75
, pp. 10106-10112
-
-
Race, R.1
Raines, A.2
Raymond, G.J.3
Caughey, B.4
Chesebro, B.5
-
58
-
-
0036387276
-
Amyloidogenic unfolding intermediates differentiate sheep prion protein variants
-
Rezaei, H., Y. Choiset, F. Eghiaian, E. Treguer, P. Mentre, P. Debey, J. Grosclaude, and T. Haertle. 2002. Amyloidogenic unfolding intermediates differentiate sheep prion protein variants. J. Mol. Biol. 322:799-814.
-
(2002)
J. Mol. Biol
, vol.322
, pp. 799-814
-
-
Rezaei, H.1
Choiset, Y.2
Eghiaian, F.3
Treguer, E.4
Mentre, P.5
Debey, P.6
Grosclaude, J.7
Haertle, T.8
-
59
-
-
0030248882
-
To what extent is strain variation evidence for an independent genome in the agent of the transmissible spongiform encephalopathies?
-
Ridley, R. M., and H. F. Baker. 1996. To what extent is strain variation evidence for an independent genome in the agent of the transmissible spongiform encephalopathies? Neurodegeneration 5:219-231.
-
(1996)
Neurodegeneration
, vol.5
, pp. 219-231
-
-
Ridley, R.M.1
Baker, H.F.2
-
60
-
-
0031720905
-
Eight prion strains have PrP(Sc) molecules with different conformations
-
Safar, J., H. Wille, V. Itri, D. Groth, H. Serban, M. Torchia, F. E. Cohen, and S. B. Prusiner. 1998. Eight prion strains have PrP(Sc) molecules with different conformations. Nat. Med. 4:1157-1165.
-
(1998)
Nat. Med
, vol.4
, pp. 1157-1165
-
-
Safar, J.1
Wille, H.2
Itri, V.3
Groth, D.4
Serban, H.5
Torchia, M.6
Cohen, F.E.7
Prusiner, S.B.8
-
61
-
-
34447127528
-
Immunohistochemistry for PrPSc in natural scrapie reveals patterns which are associated with the PrP genotype
-
Spiropoulos, J., C. Casalone, M. Caramelli, and M. M. Simmons. 2007. Immunohistochemistry for PrPSc in natural scrapie reveals patterns which are associated with the PrP genotype. Neuropathol. Appl. Neurobiol. 33:398-409.
-
(2007)
Neuropathol. Appl. Neurobiol
, vol.33
, pp. 398-409
-
-
Spiropoulos, J.1
Casalone, C.2
Caramelli, M.3
Simmons, M.M.4
-
62
-
-
33746698975
-
The physical basis of how prion conformations determine strain phenotypes
-
Tanaka, M., S. R. Collins, B. H. Toyama, and J. S. Weissman. 2006. The physical basis of how prion conformations determine strain phenotypes. Nature 442:585-589.
-
(2006)
Nature
, vol.442
, pp. 585-589
-
-
Tanaka, M.1
Collins, S.R.2
Toyama, B.H.3
Weissman, J.S.4
-
63
-
-
12644272790
-
Evidence for the conformation of the pathologic isoform of the prion protein enciphering and propagating prion diversity
-
Telling, G. C., P. Parchi, S. J. DeArmond, P. Cortelli, P. Montagna, R. Gabizon, J. Mastrianni, E. Lugaresi, P. Gambetti, and S. B. Prusiner. 1996. Evidence for the conformation of the pathologic isoform of the prion protein enciphering and propagating prion diversity. Science 274:2079-2082.
-
(1996)
Science
, vol.274
, pp. 2079-2082
-
-
Telling, G.C.1
Parchi, P.2
DeArmond, S.J.3
Cortelli, P.4
Montagna, P.5
Gabizon, R.6
Mastrianni, J.7
Lugaresi, E.8
Gambetti, P.9
Prusiner, S.B.10
-
64
-
-
33846490771
-
Proteinase K-sensitive disease-associated ovine prion protein revealed by conformation-dependent immunoassay
-
Thackray, A. M., L. Hopkins, and R. Bujdoso. 2007. Proteinase K-sensitive disease-associated ovine prion protein revealed by conformation-dependent immunoassay. Biochem. J. 401:475-483.
-
(2007)
Biochem. J
, vol.401
, pp. 475-483
-
-
Thackray, A.M.1
Hopkins, L.2
Bujdoso, R.3
-
65
-
-
36049045861
-
Mouse-adapted ovine scrapie prion strains are characterized by different conformers of PrPSc
-
Thackray, A. M., L. Hopkins, M. A. Klein, and R. Bujdoso. 2007. Mouse-adapted ovine scrapie prion strains are characterized by different conformers of PrPSc. J. Virol. 81:12119-12127.
-
(2007)
J. Virol
, vol.81
, pp. 12119-12127
-
-
Thackray, A.M.1
Hopkins, L.2
Klein, M.A.3
Bujdoso, R.4
-
66
-
-
0036168776
-
Chronic subclinical prion disease induced by low-dose inoculum
-
Thackray, A. M., M. A. Klein, A. Aguzzi, and R. Bujdoso. 2002. Chronic subclinical prion disease induced by low-dose inoculum. J. Virol. 76:2510-2517.
-
(2002)
J. Virol
, vol.76
, pp. 2510-2517
-
-
Thackray, A.M.1
Klein, M.A.2
Aguzzi, A.3
Bujdoso, R.4
-
67
-
-
0038082181
-
Subclinical prion disease induced by oral inoculation
-
Thackray, A. M., M. A. Klein, and R. Bujdoso. 2003. Subclinical prion disease induced by oral inoculation. J. Virol. 77:7991-7998.
-
(2003)
J. Virol
, vol.77
, pp. 7991-7998
-
-
Thackray, A.M.1
Klein, M.A.2
Bujdoso, R.3
-
68
-
-
3142727624
-
Conformational variation between allelic variants of cell-surface ovine prion protein
-
Thackray, A. M., S. Yang, E. Wong, T. J. Fitzmaurice, R. J. Morgan-Warren, and R. Bujdoso. 2004. Conformational variation between allelic variants of cell-surface ovine prion protein. Biochem. J. 381:221-229.
-
(2004)
Biochem. J
, vol.381
, pp. 221-229
-
-
Thackray, A.M.1
Yang, S.2
Wong, E.3
Fitzmaurice, T.J.4
Morgan-Warren, R.J.5
Bujdoso, R.6
-
69
-
-
12144291345
-
Discrimination between scrapie and bovine spongiform encephalopathy in sheep by molecular size, immunoreactivity, and glycoprofile of prion protein
-
Thuring, C. M., J. H. Erkens, J. G. Jacobs, A. Bossers, L. J. Van Keulen, G. J. Garssen, F. G. Van Zijderveld, S. J. Ryder, M. H. Groschup, T. Sweeney, and J. P. Langeveld. 2004. Discrimination between scrapie and bovine spongiform encephalopathy in sheep by molecular size, immunoreactivity, and glycoprofile of prion protein. J. Clin. Microbiol. 42:972-980.
-
(2004)
J. Clin. Microbiol
, vol.42
, pp. 972-980
-
-
Thuring, C.M.1
Erkens, J.H.2
Jacobs, J.G.3
Bossers, A.4
Van Keulen, L.J.5
Garssen, G.J.6
Van Zijderveld, F.G.7
Ryder, S.J.8
Groschup, M.H.9
Sweeney, T.10
Langeveld, J.P.11
-
70
-
-
0034973230
-
Markedly increased susceptibility to natural sheep scrapie of transgenic mice expressing ovine PrP
-
Vilotte, J. L., S. Soulier, R. Essalmani, M. G. Stinnakre, D. Vaiman, L. Lepourry, J. C. Da Silva, N. Besnard, M. Dawson, A. Buschmann, M. Groschup, S. Petit, M. F. Madelaine, S. Rakatobe, A. Le Dur, D. Vilette, and H. Laude. 2001. Markedly increased susceptibility to natural sheep scrapie of transgenic mice expressing ovine PrP. J. Virol. 75:5977-5984.
-
(2001)
J. Virol
, vol.75
, pp. 5977-5984
-
-
Vilotte, J.L.1
Soulier, S.2
Essalmani, R.3
Stinnakre, M.G.4
Vaiman, D.5
Lepourry, L.6
Da Silva, J.C.7
Besnard, N.8
Dawson, M.9
Buschmann, A.10
Groschup, M.11
Petit, S.12
Madelaine, M.F.13
Rakatobe, S.14
Le Dur, A.15
Vilette, D.16
Laude, H.17
-
71
-
-
0037041426
-
Naturally secreted oligomers of amyloid beta protein potently inhibit hippocampal long-term potentiation in vivo
-
Walsh, D. M., I. Klyubin, J. V. Fadeeva, W. K. Cullen, R. Anwyl, M. S. Wolfe, M. J. Rowan, and D. J. Selkoe. 2002. Naturally secreted oligomers of amyloid beta protein potently inhibit hippocampal long-term potentiation in vivo. Nature 416:535-539.
-
(2002)
Nature
, vol.416
, pp. 535-539
-
-
Walsh, D.M.1
Klyubin, I.2
Fadeeva, J.V.3
Cullen, W.K.4
Anwyl, R.5
Wolfe, M.S.6
Rowan, M.J.7
Selkoe, D.J.8
-
72
-
-
0025800143
-
A 'unified theory' of prion propagation
-
Weissmann, C. 1991. A 'unified theory' of prion propagation. Nature 352:679-683.
-
(1991)
Nature
, vol.352
, pp. 679-683
-
-
Weissmann, C.1
-
73
-
-
0344326239
-
Analysis of 27 mammalian and 9 avian PrPs reveals high conservation of flexible regions of the prion protein
-
Wopfner, F., G. Weidenhofer, R. Schneider, A. von Brunn, S. Gilch, T. F. Schwarz, T. Werner, and H. M. Schatzl. 1999. Analysis of 27 mammalian and 9 avian PrPs reveals high conservation of flexible regions of the prion protein. J. Mol. Biol. 289:1163-1178.
-
(1999)
J. Mol. Biol
, vol.289
, pp. 1163-1178
-
-
Wopfner, F.1
Weidenhofer, G.2
Schneider, R.3
von Brunn, A.4
Gilch, S.5
Schwarz, T.F.6
Werner, T.7
Schatzl, H.M.8
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