Ionic determinants of pH of acidic compartments under hypertonic conditions in trout hepatocytes

Journal of Experimental Biology

Volumn 211, Issue 20, 2008, Pages 3306-3314

  Ahmed, Khaled H ^a   Pelster, Bernd ^a  

^a INNSBRUCK MEDICAL UNIVERSITY   (Austria)

Author keywords

Acidic compartments; Acridine orange; Hypertonicity; Trout hepatocyte; V ATPase

Indexed keywords

ACID; ACRIDINE ORANGE; BICARBONATE; CALCIUM; CHLORIDE; HYPERTONIC SOLUTION; ION; POTASSIUM; PROTON TRANSPORTING ADENOSINE TRIPHOSPHATASE; SODIUM;

ANIMAL; ARTICLE; CELL COMPARTMENTALIZATION; CELL CULTURE; CHEMISTRY; LIVER CELL; METABOLISM; PH; TROUT;

ACIDS; ACRIDINE ORANGE; ANIMALS; BICARBONATES; CALCIUM; CELL COMPARTMENTATION; CELLS, CULTURED; CHLORIDES; HEPATOCYTES; HYDROGEN-ION CONCENTRATION; HYPERTONIC SOLUTIONS; IONS; POTASSIUM; PROTON-TRANSLOCATING ATPASES; SODIUM; TROUT;

SALMONIDAE;

EID: 55549109759     PISSN: 00220949     EISSN: None     Source Type: Journal    
DOI: 10.1242/jeb.020776     Document Type: Article

References (51)

1. 2+ and proton movements in trout hepatocytes. J. Exp. Biol. 210, 3473-3483.
2. + exchange in trout hepatocytes. J. Exp. Biol. 209, 3101-3113.
3. Al-Awqati, Q. (1995). Chloride channels of intracellular organelles. Curr. Opin. Cell Biol. 7, 504-508.
4. Al-Awqati, Q., Barasch, J. and Landry, D. (1992). Chloride channels of intracellular organelles and their potential role in cystic-fibrosis. J. Exp. Biol. 172, 245-266.
5. Boron, W. F. (2004). Regulation of intracellular pH. Adv. Physiol. Educ. 28, 160-179.
6. + exchanger isoform 6 is found in recycling endosomes of cells, not in mitochondria. Am. J. Physiol., Cell Physiol. 282, C1031-C1041.
7. Christensen, K. A., Myers, J. T. and Swanson, J. A. (2002). pH-dependent regulation of lysosomal calcium in macrophages. J. Cell Sci. 115, 599-607.
8. Demaurex, N. (2002). pH Homeostasis of cellular organelles. News Physiol. Sci. 17, 1-5.
9. Demaurex, N., Furuya, W., D?Souza, S., Bonifacino, J. S. and Grinstein, S. (1998). Mechanism of acidification of the trans-Golgi network (TGN). In situ measurements of pH using retrieval of TGN38 and furin from the cell surface. J. Biol. Chem. 273, 2044-2051.
10. 2+ by yeast vacuoles. J. Biol. Chem. 269, 7273-7278.
11. Faundez, V. and Hartzell, H. C. (2004). Intracellular chloride channels: determinants of function in the endosomal pathway. Sci. STKE 2004, re8.
12. Forgac, M. (2007). Vacuolar ATPases: rotary proton pumps in physiology and pathophysiology. Nat. Rev. Mol. Cell. Biol. 8, 917-929.
13. + exchange and osmotic shrinkage in isolated trout hepatocytes. J. Exp. Biol. 200, 2369-2376.
14. - - cotransporter in trout hepatocyte pHi regulation. J. Exp. Biol. 203, 2201-2208.
15. Futai, M., Oka, T., Moriyama, Y. and Wada, Y. (1998). Diverse roles of single membrane organelles: factors establishing the acid lumenal pH. J. Biochem. 124, 259-267.
16. Giglione, C. and Gross, J. D. (1995). Anion effects on vesicle acidification in Dictyostelium. Biochem. Mol. Biol. Int. 36, 1057-1065.
17. Grabe, M. and Oster, G. (2001). Regulation of organelle acidity. J. Gen. Physiol. 117, 329-344.
18. Haussinger, D. and Schliess, F. (1999). Osmotic induction of signaling cascades: role in regulation of cell function. Biochem. Biophys. Res. Commun. 255, 551-555.
19. Holappa, K. and Kellokumpu, S. (2003). Targeting of the AE2 anion exchanger to the Golgi apparatus is cell type-dependent and correlates with the expression of Ank(195), a Golgi membrane skeletal protein. FEBS Lett. 546, 257-264.
20. Holappa, K., Suokas, M., Soininen, P. and Kellokumpu, S. (2001). Identification of the full-length AE2 (AE2a) isoform as the Golgi-associated anion exchanger in fibroblasts. J. Histochem. Cytochem. 49, 259-269.
21. Kornfeld, S. and Mellman, I. (1989). The biogenesis of lysosomes. Annu. Rev. Cell Biol. 5, 483-525.
22. Kozin, S. V., Shkarin, P. and Gerweck, L. E. (2001). The cell transmembrane pH gradient in tumors enhances cytotoxicity of specific weak acid chemotherapeutics. Cancer Res. 61, 4740-4743.
23. Krumschnabel, G., Gstir, R., Manzl, C., Prem, C., Pafundo, D. and Schwarzbaum, P. J. (2003). Metabolic and ionic responses of trout hepatocytes to anisosmotic exposure. J. Exp. Biol. 206, 1799-1808.
24. Lang, F. (2007). Mechanisms and significance of cell volume regulation. J. Am. Coll. Nutr. 26, 613S-623S.
25. Lang, F., Busch, G. L., Ritter, M., Volkl, H., Waldegger, S., Gulbins, E. and Haussinger, D. (1998). Functional significance of cell volume regulatory mechanisms. Physiol. Rev. 78, 247-306.
26. Li, X. H. and Weinman, S. A. (2002). Chloride channels and hepatocellular function: prospects for molecular identification. Annu. Rev. Physiol. 64, 609-633.
27. Liu, C. and Hermann, T. E. (1978). Characterization of ionomycin as a calcium ionophore. J. Biol. Chem. 253, 5892-5894.
28. Llopis, J., McCaffery, J. M., Miyawaki, A., Farquhar, M. G. and Tsien, R. Y. (1998). Measurement of cytosolic, mitochondrial, and Golgi pH in single living cells with green fluorescent proteins. Proc. Natl. Acad. Sci. USA 95, 6803-6808.
29. Missiaen, L., Raeymaekers, L., Dode, L., Vanoevelen, J., Van Baelen, K., Parys, J. B., Callewaert, G., De Smedt, H., Segaert, S. and Wuytack, F. (2004). SPCA1 pumps and Hailey-Hailey disease. Biochem. Biophys. Res. Commun. 322, 1204-1213.
30. + exchanger isoforms are distributed to Golgi and post-Golgi compartments and are involved in organelle pH regulation. J. Biol. Chem. 280, 1561-1572.
31. Nilsson, C., Johansson, U., Johansson, A. C., Kagedal, K. and Ollinger, K. (2006). Cytosolic acidification and lysosomal alkalinization during TNF-alpha induced apoptosis in U937 cells. Apoptosis 11, 1149-1159.
32. + exchanger localized to the trans-Golgi network. J. Biol. Chem. 276, 17387-17394.
33. Palmgren, M. G. (1991). Acridine orange as a probe for measuring pH gradients across membranes: mechanism and limitations. Anal. Biochem. 192, 316-321.
34. Paroutis, P., Touret, N. and Grinstein, S. (2004). The pH of the secretory pathway: measurement, determinants, and regulation. Physiology 19, 207-215.
35. Pozzan, T., Rizzuto, R., Volpe, P. and Meldolesi, J. (1994). Molecular and cellular physiology of intracellular calcium stores. Physiol. Rev. 74, 595-636.
36. Puceat, M. (1999). pHi regulatory ion transporters: an update on structure, regulation and cell function. Cell. Mol. Life Sci. 55, 1216-1229.
37. Reinehr, R., Becker, S., Braun, J., Eberle, A., Grether-Beck, S. and Haussinger, D. (2006). Endosomal acidification and activation of NADPH oxidase isoforms are upstream events in hyperosmolarity-induced hepatocyte apoptosis. J. Biol. Chem. 281, 23150-23166.
38. Schapiro, F. B. and Grinstein, S. (2000). Determinants of the pH of the Golgi complex. J. Biol. Chem. 275, 21025-21032.
39. Schliess, F. and Haussinger, D. (2002). The cellular hydration state: a critical determinant for cell death and survival. Biol. Chem. 383, 577-583.
40. Schreiber, R. and Haussinger, D. (1995). Characterization of the swelling-induced alkalinization of endocytotic vesicles in fluorescein isothiocyanate-dextran-loaded rat hepatocytes. Biochem. J. 309, 19-24.
41. Schreiber, R., Stoll, B., Lang, F. and Haussinger, D. (1994). Effects of anisoosmolarity and hydroperoxides on intracellular pH in isolated rat hepatocytes as assessed by (2′,7′)-bis(carboxyethyl)-5(6)- carboxyfluorescein and fluorescein isothiocyanate-dextran fluorescence. Biochem. J. 303, 113-120.
42. Schreiber, R., Zhang, F. and Haussinger, D. (1996). Regulation of vesicular pH in liver macrophages and parenchymal cells by ammonia and anisotonicity as assessed by fluorescein isothiocyanate-dextran fluorescence. Biochem. J. 315, 385-392.
43. Seksek, O., Biwersi, J. and Verkman, A. S. (1995). Direct measurement of trans-Golgi pH in living cells and regulation by second messengers. J. Biol. Chem. 270, 4967-4970.
44. 2+ stores in bovine corneal endothelium. Invest. Ophthalmol. Vis. Sci. 43, 2341-2350.
45. Volkl, H., Busch, G. L., Haussinger, D. and Lang, F. (1994). Alkalinization of acidic cellular compartments following cell swelling. FEBS Lett. 338, 27-30.
46. Wada, Y., Ohsumi, Y. and Anraku, Y. (1992). Chloride Transport of Yeast Vacuolar Membrane-Vesicles-A Study of Invitro Vacuolar Acidification. Biochim. Biophys. Acta 1101, 296-302.
47. Walsh, P. J. (1986). Ionic requirements for intracellular pH regulation in rainbow-trout hepatocytes. Am. J. Physiol. 250, R24-R29.
48. Wehner, F., Olsen, H., Tinel, H., Kinne-Saffran, E. and Kinne, R. K. (2003). Cell volume regulation: osmolytes, osmolyte transport, and signal transduction. Rev. Physiol. Biochem. Pharmacol. 148, 1-80.
49. Weisz, O. A. (2003). Organelle acidification and disease. Traffic 4, 57-64.
50. Wu, M. M., Llopis, J., Adams, S., McCaffery, J. M., Kulomaa, M. S., Machen, T. E., Moore, H. P. and Tsien, R. Y. (2000). Organelle pH studies using targeted avidin and fluorescein-biotin. Chem. Biol. 7, 197-209.
51. Wu, M. M., Grabe, M., Adams, S., Tsien, R. Y., Moore, H. P. and Machen, T. E. (2001). Mechanisms of pH regulation in the regulated secretory pathway. J. Biol. Chem. 276, 33027-33035.