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Volumn 2, Issue 4, 2007, Pages

Extracellular sulfatases, elements of the Wnt signaling pathway, positively regulate growth and tumorigenicity of human pancreatic cancer cells

Author keywords

[No Author keywords available]

Indexed keywords

SMALL INTERFERING RNA; SULFATASE; WNT PROTEIN;

EID: 55349119506     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0000392     Document Type: Article
Times cited : (160)

References (50)
  • 1
    • 20344407571 scopus 로고    scopus 로고
    • Immunotherapy for pancreatic cancer - science driving clinical progress
    • Laheru D, Jaffee EM (2005) Immunotherapy for pancreatic cancer - science driving clinical progress. Nat Rev Cancer 5: 459-467.
    • (2005) Nat Rev Cancer , vol.5 , pp. 459-467
    • Laheru, D.1    Jaffee, E.M.2
  • 2
    • 0345059765 scopus 로고    scopus 로고
    • Hedgehog signalling in cancer formation and maintenance
    • Pasca di Magliano M, Hebrok M (2003) Hedgehog signalling in cancer formation and maintenance. Nat Rev Cancer 3: 903-911.
    • (2003) Nat Rev Cancer , vol.3 , pp. 903-911
    • Pasca di Magliano, M.1    Hebrok, M.2
  • 3
    • 17244376814 scopus 로고    scopus 로고
    • Wnt signalling in stem cells and cancer
    • Reya T, Clevers H (2005) Wnt signalling in stem cells and cancer. Nature 434: 843-850.
    • (2005) Nature , vol.434 , pp. 843-850
    • Reya, T.1    Clevers, H.2
  • 4
    • 0242268525 scopus 로고    scopus 로고
    • Widespread requirement for Hedgehog ligand stimulation in growth of digestive tract tumours
    • Berman DM, Karhadkar SS, Maitra A, Montes De Oca R, Gersteriblith MR, et al. (2003) Widespread requirement for Hedgehog ligand stimulation in growth of digestive tract tumours. Nature 425: 846-851.
    • (2003) Nature , vol.425 , pp. 846-851
    • Berman, D.M.1    Karhadkar, S.S.2    Maitra, A.3    Montes De Oca, R.4    Gersteriblith, M.R.5
  • 5
  • 6
    • 0020216124 scopus 로고
    • Many tumors induced by the mouse mammary tumor virus contain a provirus integrated in the same region of the host genome
    • Nusse R, Various HE (1982) Many tumors induced by the mouse mammary tumor virus contain a provirus integrated in the same region of the host genome. Cell 31: 99-109.
    • (1982) Cell , vol.31 , pp. 99-109
    • Nusse, R.1    Various, H.E.2
  • 7
    • 7944230668 scopus 로고    scopus 로고
    • An autocrine mechanism for constitutive Writ pathway activation in human cancer cells
    • Balico A, Liu G, Goldin L, Harris V, Aaronson SA (2004) An autocrine mechanism for constitutive Writ pathway activation in human cancer cells. Cancer Cell 6: 497-506.
    • (2004) Cancer Cell , vol.6 , pp. 497-506
    • Balico, A.1    Liu, G.2    Goldin, L.3    Harris, V.4    Aaronson, S.A.5
  • 9
    • 33646425568 scopus 로고    scopus 로고
    • Aberrant Wnt/beta-catenin signaling in pancreatic adenocarcinoma
    • Zeng G, Germinaro M, Micsenyi A, Monga. NK, Bell A, et al. (2006) Aberrant Wnt/beta-catenin signaling in pancreatic adenocarcinoma. Neoplasia 8: 279-289.
    • (2006) Neoplasia , vol.8 , pp. 279-289
    • Zeng, G.1    Germinaro, M.2    Micsenyi, A.3    Monga, N.K.4    Bell, A.5
  • 10
    • 0038133109 scopus 로고    scopus 로고
    • Dysregulation of beta-catenin expression correlates with tumor differentiation in pancreatic duct adenocarcinoma
    • Lowy AM, Fenoglio-Preiser C, Kim OJ, Kordich J, Gomez A, et al. (2003) Dysregulation of beta-catenin expression correlates with tumor differentiation in pancreatic duct adenocarcinoma. Ann Surg Oncol 10: 284-290.
    • (2003) Ann Surg Oncol , vol.10 , pp. 284-290
    • Lowy, A.M.1    Fenoglio-Preiser, C.2    Kim, O.J.3    Kordich, J.4    Gomez, A.5
  • 11
    • 17644388430 scopus 로고    scopus 로고
    • mda-7/ IL24 kills pancreatic cancer cells by inhibition of the Wnt/PI3K signaling pathways: Identification of IL-20 receptor-mediated bystander activity against pancreatic cancer
    • Chada S, Bocangel D, Ramesh R, Grimm EA, Mumm JB, et al. (2005) mda-7/ IL24 kills pancreatic cancer cells by inhibition of the Wnt/PI3K signaling pathways: identification of IL-20 receptor-mediated bystander activity against pancreatic cancer. Mol Ther 11: 724-733.
    • (2005) Mol Ther , vol.11 , pp. 724-733
    • Chada, S.1    Bocangel, D.2    Ramesh, R.3    Grimm, E.A.4    Mumm, J.B.5
  • 12
    • 0038783316 scopus 로고    scopus 로고
    • Secreted antagonists of the Wnt signalling pathway
    • Kawano Y, Kypta R (2003) Secreted antagonists of the Wnt signalling pathway. J Cell Sci 116: 2627-2634.
    • (2003) J Cell Sci , vol.116 , pp. 2627-2634
    • Kawano, Y.1    Kypta, R.2
  • 13
    • 12344310615 scopus 로고    scopus 로고
    • Functions of heparan sulfate proteoglycans in cell signaling during development
    • Lin X (2004) Functions of heparan sulfate proteoglycans in cell signaling during development. Development 131: 6009-6021.
    • (2004) Development , vol.131 , pp. 6009-6021
    • Lin, X.1
  • 14
  • 15
    • 22244480967 scopus 로고    scopus 로고
    • Glypican-3 promotes the growth of hepatocellular carcinoma by stimulating canonical Wnt signaling
    • Capurro MI, Yiang YY, Lobe C, Filmus J (2005) Glypican-3 promotes the growth of hepatocellular carcinoma by stimulating canonical Wnt signaling. Cancer Res 65: 6245-6254.
    • (2005) Cancer Res , vol.65 , pp. 6245-6254
    • Capurro, M.I.1    Yiang, Y.Y.2    Lobe, C.3    Filmus, J.4
  • 16
    • 0034947648 scopus 로고    scopus 로고
    • Molecular diversity of heparan sulfate
    • Esko JD, Lindahl U (2001) Molecular diversity of heparan sulfate. J Clin Invest 108: 169-173.
    • (2001) J Clin Invest , vol.108 , pp. 169-173
    • Esko, J.D.1    Lindahl, U.2
  • 17
    • 0034907578 scopus 로고    scopus 로고
    • Heparan sulfate: Growth control with a restricted sequence menu
    • Gallagher JT (2001) Heparan sulfate: growth control with a restricted sequence menu. J Clin Invest 108: 357-361.
    • (2001) J Clin Invest , vol.108 , pp. 357-361
    • Gallagher, J.T.1
  • 18
    • 33644657201 scopus 로고    scopus 로고
    • HSulf-2, an extracellular endoglucosamine-6-sulfatase, selectively mobilizes heparin-bound growth factors and chemokines: Effects on VEGF, FGF-1, and SDF-1
    • Uchimura K, Morimoto-Tomita M, Bistrup A, Li J, Lyon M, et al. (2006) HSulf-2, an extracellular endoglucosamine-6-sulfatase, selectively mobilizes heparin-bound growth factors and chemokines: effects on VEGF, FGF-1, and SDF-1. BMC Biochem 7: 2.
    • (2006) BMC Biochem , vol.7 , pp. 2
    • Uchimura, K.1    Morimoto-Tomita, M.2    Bistrup, A.3    Li, J.4    Lyon, M.5
  • 19
    • 0041671071 scopus 로고    scopus 로고
    • QSulf1 remodels the 6-O sulfation states of cell surface heparan sulfate proteoglycans to promote Wnt signaling
    • Ai X, Do AT, Lozynska O, Kusche-Gullberg M, Lindahl U, et al. (2003) QSulf1 remodels the 6-O sulfation states of cell surface heparan sulfate proteoglycans to promote Wnt signaling. J Cell Biol 162: 341-351.
    • (2003) J Cell Biol , vol.162 , pp. 341-351
    • Ai, X.1    Do, A.T.2    Lozynska, O.3    Kusche-Gullberg, M.4    Lindahl, U.5
  • 20
    • 0035979765 scopus 로고    scopus 로고
    • Regulation of Wnt signaling and embryo patterning by an extracellular sulfatase
    • Dhoot GK, Gustafsson MK, Ai X, Sun W, Standiford DM, et al. (2001) Regulation of Wnt signaling and embryo patterning by an extracellular sulfatase. Science 293: 1663-1666.
    • (2001) Science , vol.293 , pp. 1663-1666
    • Dhoot, G.K.1    Gustafsson, M.K.2    Ai, X.3    Sun, W.4    Standiford, D.M.5
  • 21
    • 0036198049 scopus 로고    scopus 로고
    • Identification of a novel nonlysosomal sulphatase expressed in the floor plate, choroid plexus and cartilage
    • Ohio T, Uchida H, Yamazaki H, Keino-Masu K, Matsui A, et al. (2002) Identification of a novel nonlysosomal sulphatase expressed in the floor plate, choroid plexus and cartilage. Genes Cells 7: 173-185.
    • (2002) Genes Cells , vol.7 , pp. 173-185
    • Ohio, T.1    Uchida, H.2    Yamazaki, H.3    Keino-Masu, K.4    Matsui, A.5
  • 22
    • 0037147259 scopus 로고    scopus 로고
    • Cloning and characterization of two extracellular heparin-degrading endosulfatases in mice and humans
    • Morimoto-Tomita M, Uchimura K, Werb Z, Hemmerich S, Rosen SD (2002) Cloning and characterization of two extracellular heparin-degrading endosulfatases in mice and humans. J Biol Chem 277: 49175-49185.
    • (2002) J Biol Chem , vol.277 , pp. 49175-49185
    • Morimoto-Tomita, M.1    Uchimura, K.2    Werb, Z.3    Hemmerich, S.4    Rosen, S.D.5
  • 23
    • 1242272044 scopus 로고    scopus 로고
    • Domain specific modification of HS by Qsulfl modulates the binding of the BMP antagonist Noggin
    • Viviano BL, Paine-Saunders S, Gasiunas N, Gallagher J, Saunders S (2003) Domain specific modification of HS by Qsulfl modulates the binding of the BMP antagonist Noggin. J Biol Chem 279: 5604-5611.
    • (2003) J Biol Chem , vol.279 , pp. 5604-5611
    • Viviano, B.L.1    Paine-Saunders, S.2    Gasiunas, N.3    Gallagher, J.4    Saunders, S.5
  • 24
    • 4444277251 scopus 로고    scopus 로고
    • A sulfatase regulating the migratory potency of oligodendrocyte progenitor cells through tyrosine phosphorylation of beta-catenin
    • Kakinuma Y, Saito F, Ohsawa S, Furuichi T, Miura M (2004) A sulfatase regulating the migratory potency of oligodendrocyte progenitor cells through tyrosine phosphorylation of beta-catenin. J Neurosci Res 77: 653-661.
    • (2004) J Neurosci Res , vol.77 , pp. 653-661
    • Kakinuma, Y.1    Saito, F.2    Ohsawa, S.3    Furuichi, T.4    Miura, M.5
  • 25
    • 33644658017 scopus 로고    scopus 로고
    • Sulf-2, a proangiogenic heparan sulfate endosulfatase, is upregulated in breast cancer
    • Morimoto-Tomita M, Uchimura K, Bistrup A, Lum DH, Egeblad M, et al. (2005) Sulf-2, a proangiogenic heparan sulfate endosulfatase, is upregulated in breast cancer. Neoplasia 7: 1001-1010.
    • (2005) Neoplasia , vol.7 , pp. 1001-1010
    • Morimoto-Tomita, M.1    Uchimura, K.2    Bistrup, A.3    Lum, D.H.4    Egeblad, M.5
  • 26
    • 33751083837 scopus 로고    scopus 로고
    • Heparan sulfate 6-O-endosulfatases: Discrete in vivo activities and functional cooperativity
    • Lamanna WC, Baldwin RJ, Padva. M, Kalus I, Ten Dam G, et al. (2006) Heparan sulfate 6-O-endosulfatases: discrete in vivo activities and functional cooperativity. Biochem J 400: 63-73.
    • (2006) Biochem J , vol.400 , pp. 63-73
    • Lamanna, W.C.1    Baldwin, R.J.2    Padva, M.3    Kalus, I.4    Ten Dam, G.5
  • 27
    • 33846150651 scopus 로고    scopus 로고
    • Gene trap disruption of the mouse heparan sulfate 6-O enclosulfatase, Sulf2
    • Lum DH, Tan JH, Rosen SD, Werb Z (2006) Gene trap disruption of the mouse heparan sulfate 6-O enclosulfatase, Sulf2. Mol Cell Biol 27: 678-688.
    • (2006) Mol Cell Biol , vol.27 , pp. 678-688
    • Lum, D.H.1    Tan, J.H.2    Rosen, S.D.3    Werb, Z.4
  • 28
    • 0038677717 scopus 로고    scopus 로고
    • Loss of HSulf-1 upregulates heparin-binding growth factor signaling in cancer
    • Lai J, Chien J, Staub J, Avula R, Greene EL, et al. (2003) Loss of HSulf-1 upregulates heparin-binding growth factor signaling in cancer. J Biel Chem 278: 23107-23117.
    • (2003) J Biel Chem , vol.278 , pp. 23107-23117
    • Lai, J.1    Chien, J.2    Staub, J.3    Avula, R.4    Greene, E.L.5
  • 29
    • 1442357192 scopus 로고    scopus 로고
    • HSulf-1 modulates HGF-mediated tumor cell invasion and signaling in head and neck squamous carcinoma
    • Lai JP, Chien J, Strome SE, Staub J, Montoya DIP, et al. (2004) HSulf-1 modulates HGF-mediated tumor cell invasion and signaling in head and neck squamous carcinoma. Oncogene 23: 1439-1447.
    • (2004) Oncogene , vol.23 , pp. 1439-1447
    • Lai, J.P.1    Chien, J.2    Strome, S.E.3    Staub, J.4    Montoya, D.I.P.5
  • 30
    • 9144264904 scopus 로고    scopus 로고
    • hSulf1 Sulfatase promotes apoptosis of hepatocellular cancer cells by decreasing hepayin-binding growth factor signaling
    • Lai JP, Chien JR, Moser DR, Staub JK, Aderca I, et al. (2004) hSulf1 Sulfatase promotes apoptosis of hepatocellular cancer cells by decreasing hepayin-binding growth factor signaling. Gastroenterology 126: 231-248.
    • (2004) Gastroenterology , vol.126 , pp. 231-248
    • Lai, J.P.1    Chien, J.R.2    Moser, D.R.3    Staub, J.K.4    Aderca, I.5
  • 31
    • 26844545446 scopus 로고    scopus 로고
    • Enhanced levels of Hsulf-1 interfere with heparin-binding growth factor signaling in pancreatic cancer
    • Li J, Kleeff J, Abiatari I, Kayed H, Giese NA, et al. (2005) Enhanced levels of Hsulf-1 interfere with heparin-binding growth factor signaling in pancreatic cancer. Mot Cancer 4: 14.
    • (2005) Mot Cancer , vol.4 , pp. 14
    • Li, J.1    Kleeff, J.2    Abiatari, I.3    Kayed, H.4    Giese, N.A.5
  • 32
    • 28844483193 scopus 로고    scopus 로고
    • HSulf-1 and HSulf-2 are potent inhibitors of niyeloma tumor growth in vivo
    • Dai Y, Yang Y, MacLeod V, Yoe X, Rapraeger AC, et al. (2005) HSulf-1 and HSulf-2 are potent inhibitors of niyeloma tumor growth in vivo. J Biol Chem 280: 40065-40073.
    • (2005) J Biol Chem , vol.280 , pp. 40065-40073
    • Dai, Y.1    Yang, Y.2    MacLeod, V.3    Yoe, X.4    Rapraeger, A.C.5
  • 33
    • 33744541875 scopus 로고    scopus 로고
    • SULF1 inhibits tumor growth and potentiates the effects of historic deacetylase inhibitors in hepatocedular carcinoma
    • Lai JP, Yu C, Moser CD, Aderca I, Han T, et al. (2006) SULF1 inhibits tumor growth and potentiates the effects of historic deacetylase inhibitors in hepatocedular carcinoma. Gastroenterology 130: 2130-2144.
    • (2006) Gastroenterology , vol.130 , pp. 2130-2144
    • Lai, J.P.1    Yu, C.2    Moser, C.D.3    Aderca, I.4    Han, T.5
  • 34
    • 33745728172 scopus 로고    scopus 로고
    • HSulf-1 inhibits angiogenesis and tumorigenesis in vivo
    • Narita K, Staub J, Chien J, Meyer K, Bauer M, et al. (2006) HSulf-1 inhibits angiogenesis and tumorigenesis in vivo. Cancer Res 66: 6025-6032.
    • (2006) Cancer Res , vol.66 , pp. 6025-6032
    • Narita, K.1    Staub, J.2    Chien, J.3    Meyer, K.4    Bauer, M.5
  • 35
    • 0344740017 scopus 로고    scopus 로고
    • Expression of Wnt, Frizzled, sFRP, and DKK genes in adult human pancreas
    • Heller RS, Klein T, Ling Z, Heimberg H, Katoh M, et al. (2003) Expression of Wnt, Frizzled, sFRP, and DKK genes in adult human pancreas. Gene Expr 11: 141-147.
    • (2003) Gene Expr , vol.11 , pp. 141-147
    • Heller, R.S.1    Klein, T.2    Ling, Z.3    Heimberg, H.4    Katoh, M.5
  • 36
    • 33644914996 scopus 로고    scopus 로고
    • Differential inhibition of Wnt-3a by Sfrp-1, Sfrp-2, and Sfrp-3
    • Gatti LM, Barnes T, Cheng T, Acosta L, Anglade A, et al. (2006) Differential inhibition of Wnt-3a by Sfrp-1, Sfrp-2, and Sfrp-3. Dev Dyn 235: 681-690.
    • (2006) Dev Dyn , vol.235 , pp. 681-690
    • Gatti, L.M.1    Barnes, T.2    Cheng, T.3    Acosta, L.4    Anglade, A.5
  • 37
    • 0035903106 scopus 로고    scopus 로고
    • Sequence analysis of heparan sulfate epitopes with graded affinities for fibroblast growth factors 1 and 2
    • Kreuger J, Salmivirta M, Sturiale L, Gimenez-Gallego G, Lindahl U (2001) Sequence analysis of heparan sulfate epitopes with graded affinities for fibroblast growth factors 1 and 2. J Biol Chem 276: 30744-30752.
    • (2001) J Biol Chem , vol.276 , pp. 30744-30752
    • Kreuger, J.1    Salmivirta, M.2    Sturiale, L.3    Gimenez-Gallego, G.4    Lindahl, U.5
  • 38
    • 33750705865 scopus 로고    scopus 로고
    • Establishment of the epithelial-specific transcriptome of normal and malignant human breast cells based on MPSS and array expression data
    • Grigoriadis A, Mackay A, Reis-Filho JS, Steele D, Iseli C, et al. (2006) Establishment of the epithelial-specific transcriptome of normal and malignant human breast cells based on MPSS and array expression data. Breast Cancer Res 8: R56.
    • (2006) Breast Cancer Res , vol.8
    • Grigoriadis, A.1    Mackay, A.2    Reis-Filho, J.S.3    Steele, D.4    Iseli, C.5
  • 39
    • 0037379406 scopus 로고    scopus 로고
    • Exploration of global gene expression patterns in pancreatic adenocarcinoma using cDNA microarrays
    • Iacobuzio-Donahue CA, Maitra A, Olsen M, Lowe AW, van Heek NT, et al. (2003) Exploration of global gene expression patterns in pancreatic adenocarcinoma using cDNA microarrays. Am J Pathol 162: 1151-1162.
    • (2003) Am J Pathol , vol.162 , pp. 1151-1162
    • Iacobuzio-Donahue, C.A.1    Maitra, A.2    Olsen, M.3    Lowe, A.W.4    van Heek, N.T.5
  • 40
    • 0035923521 scopus 로고    scopus 로고
    • Classification of human lung carcinomas by mRNA expression profiting reveals distinct adenocarcinoma subclasses
    • Bhattacharjee A, Richards WG, Staunton J, Li C, Monti S, et al. (2001) Classification of human lung carcinomas by mRNA expression profiting reveals distinct adenocarcinoma subclasses. Proc Natl Acad Sci U S A 98: 13790-13795.
    • (2001) Proc Natl Acad Sci U S A , vol.98 , pp. 13790-13795
    • Bhattacharjee, A.1    Richards, W.G.2    Staunton, J.3    Li, C.4    Monti, S.5
  • 41
    • 0042745472 scopus 로고    scopus 로고
    • Morimoto-Tomita MU, Kenji;Rosen, Steven D (2003) Novel extracellular sulfatases: potential roles in cancer. Trends in Glycosciences and Glycotechnology 15: 159-164.
    • Morimoto-Tomita MU, Kenji;Rosen, Steven D (2003) Novel extracellular sulfatases: potential roles in cancer. Trends in Glycosciences and Glycotechnology 15: 159-164.
  • 43
    • 33646188185 scopus 로고    scopus 로고
    • Substrate specificity and domain functions of extracellular heparan sulfate 6-O-endosulfatases, QSulF1 and QSulf2
    • Ai X, Do AT, Kusche-Gubberg M, Lindahl U, Lu K, et al. (2006) Substrate specificity and domain functions of extracellular heparan sulfate 6-O-endosulfatases, QSulF1 and QSulf2. J Biol Chem 281: 4969-4976.
    • (2006) J Biol Chem , vol.281 , pp. 4969-4976
    • Ai, X.1    Do, A.T.2    Kusche-Gubberg, M.3    Lindahl, U.4    Lu, K.5
  • 44
    • 19344362405 scopus 로고    scopus 로고
    • Trp53R172H and KrasG12D cooperate to promote chromosomal instability and widely metastatic pancreatic ductal adenocarcinoma in mice
    • Hingorani SR, Wang L, Multani AS, Combs C, Deramaudt TB, et al. (2005) Trp53R172H and KrasG12D cooperate to promote chromosomal instability and widely metastatic pancreatic ductal adenocarcinoma in mice. Cancer Cell 7: 469-483.
    • (2005) Cancer Cell , vol.7 , pp. 469-483
    • Hingorani, S.R.1    Wang, L.2    Multani, A.S.3    Combs, C.4    Deramaudt, T.B.5
  • 45
    • 13444267284 scopus 로고    scopus 로고
    • Secreted frizzled-related protein 4 is silenced by hypermethylation and induces apoptosis in beta-catenin-deficient human mesothelioma cells
    • He B, Lee AY, Dadfarmay S, You L, Xu Z, et al. (2005) Secreted frizzled-related protein 4 is silenced by hypermethylation and induces apoptosis in beta-catenin-deficient human mesothelioma cells. Cancer Res 65: 743-748.
    • (2005) Cancer Res , vol.65 , pp. 743-748
    • He, B.1    Lee, A.Y.2    Dadfarmay, S.3    You, L.4    Xu, Z.5
  • 46
    • 3142679453 scopus 로고    scopus 로고
    • Writ inhibitory factor-1 is silenced by promoter hypermethylation in human lung cancer
    • Mazieres J, He B, You L, Xu Z, Lee AY, et al. (2004) Writ inhibitory factor-1 is silenced by promoter hypermethylation in human lung cancer, Cancer Res 64: 4717-4720.
    • (2004) Cancer Res , vol.64 , pp. 4717-4720
    • Mazieres, J.1    He, B.2    You, L.3    Xu, Z.4    Lee, A.Y.5
  • 47
    • 4344570800 scopus 로고    scopus 로고
    • Inhibition of Wnt-2-mediated signaling induces programmed cell death in non-small-cell lung cancer cells
    • You L, He B, Xu Z, Uernatsu K, Mazieres J, et al. (2004) Inhibition of Wnt-2-mediated signaling induces programmed cell death in non-small-cell lung cancer cells. Oncogene 23: 6170-6174.
    • (2004) Oncogene , vol.23 , pp. 6170-6174
    • You, L.1    He, B.2    Xu, Z.3    Uernatsu, K.4    Mazieres, J.5
  • 49
    • 0043210428 scopus 로고    scopus 로고
    • Conditional suppression of cellular genes: Lentivirus vector-mediated drug-inducible RNA interference
    • Wiznerowicz M, Trono D (2003) Conditional suppression of cellular genes: lentivirus vector-mediated drug-inducible RNA interference. J Virol 77: 8957-8961.
    • (2003) J Virol , vol.77 , pp. 8957-8961
    • Wiznerowicz, M.1    Trono, D.2
  • 50
    • 0035887459 scopus 로고    scopus 로고
    • Molecular classification of human carcinomas by use of gene expression signatures
    • So AI, Welsh JB, Sapinciso LM, Kern SG, Dimitrov P, et al. (2001) Molecular classification of human carcinomas by use of gene expression signatures. Cancer Res 61: 7388-7393.
    • (2001) Cancer Res , vol.61 , pp. 7388-7393
    • So, A.I.1    Welsh, J.B.2    Sapinciso, L.M.3    Kern, S.G.4    Dimitrov, P.5


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