mda-7/IL24 kills pancreatic cancer cells by inhibition of the Wnt/PI3K signaling pathways: Identification of IL-20 receptor-mediated bystander activity against pancreatic cancer

Molecular Therapy

Volumn 11, Issue 5, 2005, Pages 724-733

  Chada, Sunil ^a,b   Bocangel, Dora ^b   Ramesh, Rajagopal ^b   Grimm, Elizabeth A ^b   Mumm, John B ^b   Mhashilkar, Abner M ^a   Zheng, Mingzhong ^a  

^a Introgen Therapeutics Inc   (United States)

^b UNIVERSITY OF TEXAS   (United States)

Author keywords

catenin; Adenovirus; Apoptosis; Cancer gene therapy; IL 10; IL 20; IL 22; IL 24; MDA 7; Receptor

Indexed keywords

ADENOVIRUS VECTOR; APC PROTEIN; BETA CATENIN; GLYCOGEN SYNTHASE KINASE 3BETA; INTERLEUKIN 20; INTERLEUKIN 24; NEUTRALIZING ANTIBODY; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; PROTEIN ANTIBODY; RECEPTOR ANTIBODY; STAT3 PROTEIN; STRESS ACTIVATED PROTEIN KINASE; WNT PROTEIN;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; BYSTANDER EFFECT; CANCER CELL; CANCER INHIBITION; CELL CYCLE G2 PHASE; CELL KILLING; CELL SPECIFICITY; CONTROLLED STUDY; CYTOTOXICITY; ENZYME ACTIVATION; ENZYME REGULATION; GENE THERAPY; GENETIC TRANSDUCTION; HUMAN; HUMAN CELL; MITOSIS INHIBITION; PANCREAS CANCER; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN FUNCTION; SIGNAL TRANSDUCTION; VIRAL GENE DELIVERY SYSTEM;

1-PHOSPHATIDYLINOSITOL 3-KINASE; APOPTOSIS; BETA CATENIN; BYSTANDER EFFECT; CYTOSKELETAL PROTEINS; GENES, TUMOR SUPPRESSOR; GENETIC VECTORS; HUMANS; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; INTERLEUKINS; PANCREATIC NEOPLASMS; RECEPTORS, INTERLEUKIN; SIGNAL TRANSDUCTION; TIME FACTORS; TRANS-ACTIVATORS; WNT PROTEINS;

ADENOVIRIDAE;

EID: 17644388430     PISSN: 15250016     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ymthe.2004.12.021     Document Type: Article

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