Histopathology of experimentally induced asthma in a murine model of sickle cell disease

Blood

Volumn 112, Issue 6, 2008, Pages 2529-2538

  Nandedkar, Sandhya D ^a   Feroah, Thomas R ^a   Hutchins, William ^a   Weihrauch, Dorothee ^a   Konduri, Kameswari S ^a   Wang, Jingli ^a   Strunk, Robert C ^b   DeBaun, Michael R ^b   Hillery, Cheryl A ^c   Pritchard, Kirkwood A ^a,c  

^a MEDICAL COLLEGE OF WISCONSIN   (United States)

^b WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c CHILDREN S HOSPITAL OF WISCONSIN   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CALVASCULIN; EOSINOPHIL PEROXIDASE; HEMOGLOBIN; IMMUNOGLOBULIN E; OVALBUMIN; TRANSFORMING GROWTH FACTOR BETA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ASTHMA; CONTROLLED STUDY; DISEASE SEVERITY; ENZYME ACTIVITY; EOSINOPHIL; EXPERIMENTAL MOUSE; HISTOPATHOLOGY; IMMUNOFLUORESCENCE; IMMUNOREACTIVITY; LUNG LAVAGE; MORTALITY; MOUSE; NONHUMAN; PNEUMONIA; PRIORITY JOURNAL; PROTEIN EXPRESSION; SICKLE CELL ANEMIA; ANIMAL; CHEMICALLY INDUCED DISORDER; DISEASE MODEL; HUMAN; IMMUNOLOGY; INFLAMMATION; LUNG; PATHOLOGY; SURVIVAL RATE;

ANEMIA, SICKLE CELL; ANIMALS; ASTHMA; DISEASE MODELS, ANIMAL; HEMOGLOBINS; HUMANS; INFLAMMATION; LUNG; MICE; OVALBUMIN; SURVIVAL RATE;

EID: 55249127378     PISSN: 00064971     EISSN: 15280020     Source Type: Journal    
DOI: 10.1182/blood-2008-01-132506     Document Type: Article

References (40)

1. Miller ST, Sleeper LA, Pegelow CH, et al. Prediction of adverse outcomes in children with sickle cell disease. N Engl J Med. 2000;342:83-89.
2. Balkaran B, Char G, Morris JS, Thomas PW, Serjeant BE, Serjeant GR. Stroke in a cohort of patients with homozygous sickle cell disease. J Pediatr. 1992;120:360-366.
3. Kinney TR, Sleeper LA, Wang WC, et al. Silent cerebral infarcts in sickle cell anemia: a risk factor analysis: The Cooperative Study of Sickle Cell Disease. Pediatrics. 1999;103:640-645.
4. Platt OS, Brambilla DJ, Rosse WF, et al. Mortality in sickle cell disease. Life expectancy and risk factors for early death. N Engl J Med. 1994;330: 1639-1644.
5. Stuart J, Stone PC, Akinola NO, Gallimore JR, Pepys MB. Monitoring the acute phase response to vaso-occlusive crisis in sickle cell disease. J Clin Pathol. 1994:47:166-169.
6. Solovey A, Lin Y, Browne P, Choong S, Wayner E, Hebbel RP. Circulating activated endothelial cells in sickle cell anemia. N Engl J Med. 1997;337: 1584-1590.
7. Solovey AA, Solovey AN, Harkness J, Hebbel RP. Modulation of endothelial cell activation in sickle cell disease: a pilot study. Blood. 2001;97:1937-1941.
8. SoloveyA, Kollander R, Shet A. etal. Endothelial cell expression of tissue factor in sickle mice is augmented by hypoxia/reoxygenation and inhibited by lovastatin. Blood. 2004:104:840-846.
9. PathareA, Al Kindi S, AlnaqdyAA, Daar S, Knox-Macaulay H, Dennison D. Cytokine profile of sickle cell disease in Oman. Am J Hematol. 2004; 77:323-328.
10. Belcher JD, Bryant CJ, Nguyen J, et al. Transgenic sickle mice have vascular inflammation. Blood. 2003;101:3953-3959.
11. Holtzclaw JD, Jack D. Aguayo SM, Eckman JR, Roman J, Hsu LL. Enhanced pulmonary and systemic response to endotoxin in transgenic sickle mice. Am J Respir Crit Care Med. 2004;169:687-695.
12. Asthma prevalence and control characteristics by race/ethnicity: United States, 2002. MMWR Morb Mortal Wkly Rep. 2004;53:145-148.
13. Boyd JH, Macklin EA, Strunk RC, DeBaun MR. Asthma is associated with acute chest syndrome and pain in children with sickle cell anemia. Blood. 2006;108:2923-2927.
14. Boyd JH, Moinuddin A, Strunk RC, DeBaun MR. Asthma and acute chest in sickle-cell disease. Pediatr Pulmonol. 2004;38:229-232.
15. Boyd JH, Macklin EA, Strunk RC, DeBaun MR. Asthma is associated with increased mortality in individuals with sickle cell anemia. Haematologica. 2007;92:1115-1118.
16. de Siqueira AL, Russo M, Steil AA, Facincone S, Mariano M, Jancar S. A new murine model of pulmonary eosinophilic hypersensitivity: contribution to experimental asthma. J Allergy Clin Immunol. 1997;100:383-388.
17. Konduri KS, Nandedkar S, Duzgunes N, et al. Efficacy of liposomal budesonide in experimental asthma. J Allergy Clin Immunol. 2003;111:321-327.
18. Pászty C, Brion CM, Manci E, et al. Transgenic knockout mice with exclusively human sickle hemoglobin and sickle cell disease. Science. 1997; 278:876-878.
19. Manci EA, Hillery CA, Bodian CA, Zhang ZG, Lutty GA, Coller BS. Pathology of Berkeley sickle cell mice: similarities and differences with human sickle cell disease. Blood. 2006;107:1651-1658.
20. Zhang Y, Lamm WJ, Albert RK, Chi EY, Henderson WR Jr, Lewis DB. Influence of the route of allergen administration and genetic background on the murine allergic pulmonary response. Am J Respir Crit Care Med. 1997;155:661-669.
21. Chang YS, Kim YK, Bahn JW, et al. Comparison of asthma phenotypes using different sensitizing protocols in mice. Korean J Intern Med. 2005;20: 152-158.
22. Schneider T, Issekutz AC. Quantitation of eosinophil and neutrophil infiltration intor rat lung by specific assays for eosinophil peroxidase and myeloperoxidase: application in a Brown Norway rat model of allergic pulmonary inflammation. J Immunol Methods. 1996;198:1-14.
23. Sunyer J, Anto JM, Castellsague J, Soriano JB, Roca J. Total serum lgE is associated with asthma independently of specific lgE levels: The Spanish Group of the European Study of Asthma. Eur Respir J. 1996;9:1880-1884.
24. Koh YI, Choi S. Blood eosinophil counts for the prediction of the severity of exercise-induced bronchospasm in asthma. Respir Med. 2002;96: 120-125.
25. Wolyniec WW, De Sanctis GT Nabozny G, et al. Reduction of antigen-induced airway hyperreactivity and eosinophilia in ICAM-1-deficient mice. Am J Respir Cell Mol Biol. 1998;18:777-785.
26. Williams TJ. The eosinophil enigma. J Clin Invest. 2004;113:507-509.
27. Arciniegas E, Frid MG, Douglas IS, Stenmark KR. Perspectives on endothelial-to-mesenchymal transition: potential contribution to vascular remodeling in chronic pulmonary hypertension. Am J Physiol Lung Cell Mol Physiol. 2007;293: L1-L8.
28. Pritchard KA Jr, Ou J, Ou Z, et al. Hypoxiainduced acute lung injury in murine models of sickle cell disease. Am J Physiol Lung Cell Mol Physiol. 2004;286:L705-L714.
29. Jison ML, Munson PJ, Barb JJ, et al. Blood mononuclear cell gene expression profiles characterize the oxidant, hemolytic, and inflammatory stress of sickle cell disease. Blood. 2004; 104: 270-280.
30. Belcher JD, Marker PH, Weber JP, Hebbel RP, Vercellotti GM. Activated monocytes in sickle cell disease: potential role in the activation of vascular endothelium and vaso-occlusion. Blood. 2000; 96:2451-2459.
31. Chies JA, Nardi NB. Sickle cell disease: a chronic inflammatory condition. Med Hypotheses. 2001; 57:46-50.
32. Greenough A. Sickle cell disease: pulmonary complications and a proinflammatory state? Am J Respir Grit Care Med. 2004;169:663-665.
33. Hebbel RP, Osarogiagbon R, Kaul D. The endothelial biology of sickle cell disease: inflammation and a chronic vasculopathy. Microcirculation. 2004;11:129-151.
34. Hibbert JM, Hsu LL, Bhathena SJ, et al. Proinflammatory cytokines and the hypermetabolism of children with sickle cell disease. Exp Biol Med (Maywood). 2005;230:68-74.
35. Platt OS. Sickle cell anemia as an inflammatory disease. J Clin Invest. 2000;106:337-338.
36. Cho JY, Miller M, Baek KJ, et al. Inhibition of airway remodeling in IL-5-deficient mice. J Clin Invest. 2004;113:551-560.
37. TatlerAL, Porte J, Knox A, Jenkins G, Pang L. Tryptase activates TGFbeta in human airway smooth muscle cells via direct proteolysis. Biochem Biophys Res Commun. 2008;370:239-242.
38. Kobayashi M, Sugiyama H, Wang DH, et al. Catalase deficiency renders remnant kidneys more susceptible to oxidant tissue injury and renal fibrosis in mice. Kidney Int. 2005;68:1018-1031.
39. Okada H, Danoff TM, Kalluri R, Neilson EG. Early role of Fsp1 in epithelial-mesenchymal transformation. Am J Physiol. 1997;273:F563-F574.
40. Ramirez A, Ramadan B, Ritzenthaler JD, Rivera HN, Jones DP, Roman J. Extracellular cysteine/cystine redox potential controls lung fibroblast proliferation and matrix expression through upregulation of transforming growth factor-beta. Am J Physiol Lung Cell Mol Physiol. 2007;293: L972-L981.