Synthesis of β-hydroxy-α-amino acids with a reengineered alanine racemase

Bioorganic and Medicinal Chemistry Letters

Volumn 18, Issue 22, 2008, Pages 5987-5990

  Fesko, Kateryna ^a,b   Giger, Lars ^a   Hilvert, Donald ^a  

^a ETH ZURICH   (Switzerland)

^b GRAZ UNIVERSITY OF TECHNOLOGY   (Austria)

Author keywords

Alanine racemase; Aldol reaction; Amino acids; Biocatalysis; Threonine aldolase

Indexed keywords

ALANINE; ALANINE RACEMASE; ALDEHYDE DERIVATIVE; AMINO ACID DERIVATIVE; FRUCTOSE BISPHOSPHATE ALDOLASE; GLYCINE; MUTANT PROTEIN; THREONINE;

ALDOL REACTION; AMINO ACID SYNTHESIS; ARTICLE; CATALYST; ENZYME ENGINEERING; ENZYME SPECIFICITY; STEREOCHEMISTRY;

ALANINE; ALANINE RACEMASE; ALDEHYDES; AMINO ACIDS; BACTERIA; CATALYSIS; COMBINATORIAL CHEMISTRY TECHNIQUES; GLYCINE; GLYCINE HYDROXYMETHYLTRANSFERASE; MOLECULAR STRUCTURE; PROTEIN ENGINEERING; PYRIDOXAL PHOSPHATE; STEREOISOMERISM;

EID: 55249099063     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2008.08.031     Document Type: Article

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