-
1
-
-
0035163909
-
X-linked neonatal diabetes mellitus, enteropathy and endocrinopathy syndrome is the human equivalent of mouse scurfy
-
Wildin RS, Ramsdell F, Peake J, et al. X-linked neonatal diabetes mellitus, enteropathy and endocrinopathy syndrome is the human equivalent of mouse scurfy. Nat Genet 2001; 27:18-20.
-
(2001)
Nat Genet
, vol.27
, pp. 18-20
-
-
Wildin, R.S.1
Ramsdell, F.2
Peake, J.3
-
2
-
-
0035167967
-
-
Bennett CL, Christie J, Ramsdell F, et al. The immune dysregulation, polyendocrinopathy, enteropathy, X-linked syndrome (IPEX) is caused by mutations of FOXP3. Nat Genet 2001; 27:20-21.
-
Bennett CL, Christie J, Ramsdell F, et al. The immune dysregulation, polyendocrinopathy, enteropathy, X-linked syndrome (IPEX) is caused by mutations of FOXP3. Nat Genet 2001; 27:20-21.
-
-
-
-
3
-
-
33749852275
-
The role of HLA promoters in autoimmunity
-
Müller-Hilke B, Mitchison NA. The role of HLA promoters in autoimmunity. Curr Pharm Des 2006; 12:3743-3752.
-
(2006)
Curr Pharm Des
, vol.12
, pp. 3743-3752
-
-
Müller-Hilke, B.1
Mitchison, N.A.2
-
4
-
-
38649125210
-
Genome-wide association scan in women with systemic lupus erythematosus identifies susceptibility variants in ITGAM, PXK, KIAA1542 and other loci
-
GWAS performed in large number of European adults with SLE identified new susceptibility loci, which may also be important in pediatric disease. International Consortium for Systemic Lupus Erythematosus Genetics SLEGEN
-
International Consortium for Systemic Lupus Erythematosus Genetics (SLEGEN), Harley JB, Alarcon-Riquelme ME, Criswell LA, et al. Genome-wide association scan in women with systemic lupus erythematosus identifies susceptibility variants in ITGAM, PXK, KIAA1542 and other loci. Nat Genet 2008; 40:204-210. GWAS performed in large number of European adults with SLE identified new susceptibility loci, which may also be important in pediatric disease.
-
(2008)
Nat Genet
, vol.40
, pp. 204-210
-
-
Harley, J.B.1
Alarcon-Riquelme, M.E.2
Criswell, L.A.3
-
5
-
-
33846621003
-
A genomewide linkage analysis of Kawasaki disease: Evidence for linkage to chromosome 12
-
Onouchi Y, Tamari M, Takahashi A, et al. A genomewide linkage analysis of Kawasaki disease: evidence for linkage to chromosome 12. J Hum Genet 2007; 52:179-190.
-
(2007)
J Hum Genet
, vol.52
, pp. 179-190
-
-
Onouchi, Y.1
Tamari, M.2
Takahashi, A.3
-
6
-
-
0033502508
-
Age-specific effects of juvenile rheumatoid arthritis- associated HLA alleles
-
Murray KJ, Moroldo MB, Donnelly P, et al. Age-specific effects of juvenile rheumatoid arthritis- associated HLA alleles. Arthritis Rheum 1999; 42:1843-1853.
-
(1999)
Arthritis Rheum
, vol.42
, pp. 1843-1853
-
-
Murray, K.J.1
Moroldo, M.B.2
Donnelly, P.3
-
7
-
-
4344625900
-
Genetics of juvenile idiopathic arthritis: An update
-
Prahalad S. Genetics of juvenile idiopathic arthritis: an update. Curr Opin Rheumatol 2004; 16:588-594.
-
(2004)
Curr Opin Rheumatol
, vol.16
, pp. 588-594
-
-
Prahalad, S.1
-
8
-
-
33746894198
-
Genomic progress in pediatric arthritis: Recent work and future goals
-
Phelan JD, Thompson SD. Genomic progress in pediatric arthritis: recent work and future goals. Curr Opin Rheumatol 2006; 18:482-489.
-
(2006)
Curr Opin Rheumatol
, vol.18
, pp. 482-489
-
-
Phelan, J.D.1
Thompson, S.D.2
-
9
-
-
35948977330
-
Genetic determinants of diabetes are similarly associated with other immune-mediated diseases
-
Duffy DL. Genetic determinants of diabetes are similarly associated with other immune-mediated diseases. Curr Opin Allergy Clin Immunol 2007;7:468-474.
-
(2007)
Curr Opin Allergy Clin Immunol
, vol.7
, pp. 468-474
-
-
Duffy, D.L.1
-
10
-
-
37549027202
-
-
Onouchi Y, Gunji T, Burns JC, et al. ITPKC functional polymorphism associated with Kawasaki disease susceptibility and formation of coronary artery aneurysms. Nat Genet 2008; 40:35-42. Original work describing a new functional polymorphism of ITPKC, its role as a negative regulator of T-cell activation, and its relationship to Kawasaki disease susceptibility in Japanese and US patient populations. The results of the study have clinical applications; the identification of potentially IVIG-resistant patients (those found to have the itpkc-3 C allele) may direct the early use of different treatments.
-
Onouchi Y, Gunji T, Burns JC, et al. ITPKC functional polymorphism associated with Kawasaki disease susceptibility and formation of coronary artery aneurysms. Nat Genet 2008; 40:35-42. Original work describing a new functional polymorphism of ITPKC, its role as a negative regulator of T-cell activation, and its relationship to Kawasaki disease susceptibility in Japanese and US patient populations. The results of the study have clinical applications; the identification of potentially IVIG-resistant patients (those found to have the itpkc-3 C allele) may direct the early use of different treatments.
-
-
-
-
11
-
-
40049093765
-
Systemic lupus erythematosus
-
Rahman A, Isenberg DA. Systemic lupus erythematosus. N Engl J Med 2008; 358:929-939.
-
(2008)
N Engl J Med
, vol.358
, pp. 929-939
-
-
Rahman, A.1
Isenberg, D.A.2
-
12
-
-
34948828021
-
-
Kallel-Sellami M, Baili-Klila L, Zerzeri Y, et al. Pediatric systemic lupus erythematosus with C1q deficiency. Ann N Y Acad Sci 2007; 1108:193-196. A case report of a pediatric patient with C1q deficiency and SLE with a thorough review of C1q clinical presentation, epidemiology, and immunologic findings.
-
Kallel-Sellami M, Baili-Klila L, Zerzeri Y, et al. Pediatric systemic lupus erythematosus with C1q deficiency. Ann N Y Acad Sci 2007; 1108:193-196. A case report of a pediatric patient with C1q deficiency and SLE with a thorough review of C1q clinical presentation, epidemiology, and immunologic findings.
-
-
-
-
13
-
-
0034007104
-
Links between complement abnormalities and systemic lupus erythematosus
-
Pickering MC, Walport MJ. Links between complement abnormalities and systemic lupus erythematosus. Rheumatology (Oxford) 2000; 39:133-141.
-
(2000)
Rheumatology (Oxford)
, vol.39
, pp. 133-141
-
-
Pickering, M.C.1
Walport, M.J.2
-
15
-
-
0035170160
-
HLA-DRB1 antigens in Taiwanese patients with juvenile-onset systemic lupus erythematosus
-
Huang JL, Shaw CK, Lee A, et al. HLA-DRB1 antigens in Taiwanese patients with juvenile-onset systemic lupus erythematosus. Rheumatol Int 2001; 21:103-105.
-
(2001)
Rheumatol Int
, vol.21
, pp. 103-105
-
-
Huang, J.L.1
Shaw, C.K.2
Lee, A.3
-
16
-
-
0037984420
-
Analysis of human leukocyte antigens class II-DR in Brazilian children and adolescents with systemic lupus erythematosus
-
Liphaus Bde L, Goldberg AC, Kiss MH, et al. Analysis of human leukocyte antigens class II-DR in Brazilian children and adolescents with systemic lupus erythematosus. Rev Hosp Clin Fac Med Sao Paulo 2002; 57:277-282.
-
(2002)
Rev Hosp Clin Fac Med Sao Paulo
, vol.57
, pp. 277-282
-
-
Liphaus Bde, L.1
Goldberg, A.C.2
Kiss, M.H.3
-
17
-
-
33846957729
-
Association analysis of the PTPN22 gene in childhood-onset systemic lupus erythematosus in Mexican population
-
Baca V, Velazquez-Cruz R, Salas-Martinez G, et al. Association analysis of the PTPN22 gene in childhood-onset systemic lupus erythematosus in Mexican population. Genes Immun 2006; 7:693-695.
-
(2006)
Genes Immun
, vol.7
, pp. 693-695
-
-
Baca, V.1
Velazquez-Cruz, R.2
Salas-Martinez, G.3
-
18
-
-
34250369117
-
-
Reddy MV, Velazquez-Cruz R, Baca V, et al. Genetic association of IRF5 with SLE in Mexicans: higher frequency of the risk haplotype and its homozygozity than Europeans. Hum Genet 2007; 121:721-727. Case-control analysis showing the strong presence of three IRF5 gene polymorphisms in Mexican patients with SLE. There was a higher association of these polymorphisms in the Mexican population with SLE than in Europeans; the authors suggest this may relate to the more aggressive disease course experienced by some Mexican patients.
-
Reddy MV, Velazquez-Cruz R, Baca V, et al. Genetic association of IRF5 with SLE in Mexicans: higher frequency of the risk haplotype and its homozygozity than Europeans. Hum Genet 2007; 121:721-727. Case-control analysis showing the strong presence of three IRF5 gene polymorphisms in Mexican patients with SLE. There was a higher association of these polymorphisms in the Mexican population with SLE than in Europeans; the authors suggest this may relate to the more aggressive disease course experienced by some Mexican patients.
-
-
-
-
19
-
-
33847208544
-
-
Velazquez-Cruz R, Orozco L, Espinosa-Rosales F, et al. Association of PDCD1 polymorphisms with childhood-onset systemic lupus erythematosus. Eur J Hum Genet 2007; 15:336-341. A case-control study which identified PDCD1.3A SNP as a risk factor for susceptibility in childhood-onset SLE in a Mexican population. An increased association was not found for a previously identified polymorphism associated with lupus nephritis.
-
Velazquez-Cruz R, Orozco L, Espinosa-Rosales F, et al. Association of PDCD1 polymorphisms with childhood-onset systemic lupus erythematosus. Eur J Hum Genet 2007; 15:336-341. A case-control study which identified PDCD1.3A SNP as a risk factor for susceptibility in childhood-onset SLE in a Mexican population. An increased association was not found for a previously identified polymorphism associated with lupus nephritis.
-
-
-
-
20
-
-
5044220049
-
Polymorphisms in the promoter region of RANTES and the regulatory region of monocyte chemoattractant protein-1 among Chinese children with systemic lupus erythematosus
-
Liao CH, Yao TC, Chung HT, et al. Polymorphisms in the promoter region of RANTES and the regulatory region of monocyte chemoattractant protein-1 among Chinese children with systemic lupus erythematosus. J Rheumatol 2004; 31:2062-2067.
-
(2004)
J Rheumatol
, vol.31
, pp. 2062-2067
-
-
Liao, C.H.1
Yao, T.C.2
Chung, H.T.3
-
21
-
-
33845599505
-
Immunogenetic risk and protective factors for juvenile dermatomyositis in Caucasians
-
Mamyrova G, O'Hanlon TP, Monroe JB, et al. Immunogenetic risk and protective factors for juvenile dermatomyositis in Caucasians. Arthritis Rheum 2006; 54:3979-3987.
-
(2006)
Arthritis Rheum
, vol.54
, pp. 3979-3987
-
-
Mamyrova, G.1
O'Hanlon, T.P.2
Monroe, J.B.3
-
22
-
-
18544367934
-
Visualizing human leukocyte antigen class II risk haplotypes in human systemic lupus erythematosus
-
Graham RR, Ortmann WA, Langefeld CD, et al. Visualizing human leukocyte antigen class II risk haplotypes in human systemic lupus erythematosus. Am J Hum Genet 2002; 71:543-553.
-
(2002)
Am J Hum Genet
, vol.71
, pp. 543-553
-
-
Graham, R.R.1
Ortmann, W.A.2
Langefeld, C.D.3
-
23
-
-
0033521596
-
Cooperative inhibition of T-cell antigen receptor signaling by a complex between a kinase and a phosphatase
-
Cloutier JF, Veillette A. Cooperative inhibition of T-cell antigen receptor signaling by a complex between a kinase and a phosphatase. J Exp Med 1999; 189:111-121.
-
(1999)
J Exp Med
, vol.189
, pp. 111-121
-
-
Cloutier, J.F.1
Veillette, A.2
-
24
-
-
37449023760
-
-
Chung SA, Criswell LA. PTPN22: its role in SLE and autoimmunity. Auto-immunity 2007; 40:582-590.
-
Chung SA, Criswell LA. PTPN22: its role in SLE and autoimmunity. Auto-immunity 2007; 40:582-590.
-
-
-
-
25
-
-
33645317378
-
The association of PTPN22 with rheumatoid arthritis and juvenile idiopathic arthritis
-
Hinks A, Worthington J, Thomson W. The association of PTPN22 with rheumatoid arthritis and juvenile idiopathic arthritis. Rheumatology (Oxford) 2006; 45:365-368.
-
(2006)
Rheumatology (Oxford)
, vol.45
, pp. 365-368
-
-
Hinks, A.1
Worthington, J.2
Thomson, W.3
-
26
-
-
40349109578
-
Genetic variation in PTPN22 corresponds to altered function of T and B lymphocytes
-
Rieck M, Arechiga A, Onengut-Gumuscu S, et al. Genetic variation in PTPN22 corresponds to altered function of T and B lymphocytes. J Immunol 2007; 179:4704-4710.
-
(2007)
J Immunol
, vol.179
, pp. 4704-4710
-
-
Rieck, M.1
Arechiga, A.2
Onengut-Gumuscu, S.3
-
27
-
-
37149055953
-
Association of an IRF5 gene functional polymorphism with Sjogren's syndrome
-
Miceli-Richard C, Comets E, Loiseau P, et al. Association of an IRF5 gene functional polymorphism with Sjogren's syndrome. Arthritis Rheum 2007; 56:3989-3994.
-
(2007)
Arthritis Rheum
, vol.56
, pp. 3989-3994
-
-
Miceli-Richard, C.1
Comets, E.2
Loiseau, P.3
-
29
-
-
20744441837
-
Association of a PDCD1 polymorphism with renal manifestations in systemic lupus erythematosus
-
Johansson M, Arlestig L, Moller B, et al. Association of a PDCD1 polymorphism with renal manifestations in systemic lupus erythematosus. Arthritis Rheum 2005; 52:1665-1669.
-
(2005)
Arthritis Rheum
, vol.52
, pp. 1665-1669
-
-
Johansson, M.1
Arlestig, L.2
Moller, B.3
-
30
-
-
34248571410
-
Mary Kirkland Center for Lupus Research Consortium. Biology of the sex and age distribution of systemic lupus erythematosus
-
Lockshin MD, Mary Kirkland Center for Lupus Research Consortium. Biology of the sex and age distribution of systemic lupus erythematosus. Arthritis Rheum 2007; 57:608-611.
-
(2007)
Arthritis Rheum
, vol.57
, pp. 608-611
-
-
Lockshin, M.D.1
-
31
-
-
34548431050
-
Distinctive clinical features of pediatric systemic lupus erythematosus in three different age classes
-
Pluchinotta FR, Schiavo B, Vittadello F, et al. Distinctive clinical features of pediatric systemic lupus erythematosus in three different age classes. Lupus 2007; 16:550-555.
-
(2007)
Lupus
, vol.16
, pp. 550-555
-
-
Pluchinotta, F.R.1
Schiavo, B.2
Vittadello, F.3
-
32
-
-
42149116947
-
Cutting edge: Progesterone regulates IFN-alpha production by plasmacytoid dendritic cells
-
Hughes GC, Thomas S, Li C, et al. Cutting edge: progesterone regulates IFN-alpha production by plasmacytoid dendritic cells. J Immunol 2008; 180:2029-2033.
-
(2008)
J Immunol
, vol.180
, pp. 2029-2033
-
-
Hughes, G.C.1
Thomas, S.2
Li, C.3
-
33
-
-
4644289773
-
Association of the oestrogen receptor alpha gene polymorphisms with disease onset in systemic lupus erythematosus
-
Lee YJ, Shin KS, Kang SW, et al. Association of the oestrogen receptor alpha gene polymorphisms with disease onset in systemic lupus erythematosus. Ann Rheum Dis 2004; 63:1244-1249.
-
(2004)
Ann Rheum Dis
, vol.63
, pp. 1244-1249
-
-
Lee, Y.J.1
Shin, K.S.2
Kang, S.W.3
-
34
-
-
31044433220
-
An altered immune response to Epstein-Barr nuclear antigen 1 in pediatric systemic lupus erythematosus
-
McClain MT, Poole BD, Bruner BF, et al. An altered immune response to Epstein-Barr nuclear antigen 1 in pediatric systemic lupus erythematosus. Arthritis Rheum 2006; 54:360-368.
-
(2006)
Arthritis Rheum
, vol.54
, pp. 360-368
-
-
McClain, M.T.1
Poole, B.D.2
Bruner, B.F.3
-
35
-
-
0036657108
-
Dermatomyositis in two siblings and a brief review of familial dermatomyositis
-
Tsao CY, Mendell JR, Kissel JT. Dermatomyositis in two siblings and a brief review of familial dermatomyositis. J Child Neurol 2002; 17:540-542.
-
(2002)
J Child Neurol
, vol.17
, pp. 540-542
-
-
Tsao, C.Y.1
Mendell, J.R.2
Kissel, J.T.3
-
36
-
-
0031901493
-
Clinical, serologic, and immunogenetic features of familial idiopathic inflammatory myopathy
-
Rider LG, Gurley RC, Pandey JP, et al. Clinical, serologic, and immunogenetic features of familial idiopathic inflammatory myopathy. Arthritis Rheum 1998; 41:710-719.
-
(1998)
Arthritis Rheum
, vol.41
, pp. 710-719
-
-
Rider, L.G.1
Gurley, R.C.2
Pandey, J.P.3
-
37
-
-
0029562016
-
Association of the HLA-DQA1 0501 allele in multiple racial groups with juvenile dermatomyositis
-
Reed AM, Stirling JD. Association of the HLA-DQA1 0501 allele in multiple racial groups with juvenile dermatomyositis. Human Immunol 1995; 44:131-135.
-
(1995)
Human Immunol
, vol.44
, pp. 131-135
-
-
Reed, A.M.1
Stirling, J.D.2
-
38
-
-
36549041054
-
-
Wedderburn LR, McHugh NJ, Chinoy H, et al., Juvenile Dermatomyositis Research Group (JDRG). HLA class II haplotype and autoantibody associations in children with juvenile dermatomyositis and juvenile dermatomyositisscleroderma overlap. Rheumatology (Oxford) 2007; 46:1786-1791. This study identifies significant associations between HLA class II haplotypes and autoantibody associations in Caucasian pediatric patients with JDM and JDM/SSc, demonstrating genetic and serologic differences between the groups.
-
Wedderburn LR, McHugh NJ, Chinoy H, et al., Juvenile Dermatomyositis Research Group (JDRG). HLA class II haplotype and autoantibody associations in children with juvenile dermatomyositis and juvenile dermatomyositisscleroderma overlap. Rheumatology (Oxford) 2007; 46:1786-1791. This study identifies significant associations between HLA class II haplotypes and autoantibody associations in Caucasian pediatric patients with JDM and JDM/SSc, demonstrating genetic and serologic differences between the groups.
-
-
-
-
40
-
-
0031033610
-
Molecular modelling of HLA-DQ suggests a mechanism of resistance in type 1 diabetes
-
Hoover ML, Marta RT. Molecular modelling of HLA-DQ suggests a mechanism of resistance in type 1 diabetes. Scand J Immunol 1997; 45:193-202.
-
(1997)
Scand J Immunol
, vol.45
, pp. 193-202
-
-
Hoover, M.L.1
Marta, R.T.2
-
41
-
-
1642382026
-
HLA class I noninherited maternal antigens in cord blood and breast milk
-
Molitor ML, Haynes LD, Jankowska-Gan E, et al. HLA class I noninherited maternal antigens in cord blood and breast milk. Hum Immunol 2004; 65:231-239.
-
(2004)
Hum Immunol
, vol.65
, pp. 231-239
-
-
Molitor, M.L.1
Haynes, L.D.2
Jankowska-Gan, E.3
-
42
-
-
42749084094
-
-
Maternal microchimerism is found in blood and tissues of patients with autoimmune disease. This review defines microchimerism, and describes mechanisms by which chimeric cells may contribute to autoimmunity
-
Stevens AM. Do maternal cells trigger or perpetuate autoimmune diseases in children? Pediatr Rheumatol Online J 2007; 5:9. Maternal microchimerism is found in blood and tissues of patients with autoimmune disease. This review defines microchimerism, and describes mechanisms by which chimeric cells may contribute to autoimmunity.
-
(2007)
Do maternal cells trigger or perpetuate autoimmune diseases in children? Pediatr Rheumatol Online J
, vol.5
, pp. 9
-
-
Stevens, A.M.1
-
43
-
-
0033856804
-
Noninherited maternal antigens do not play a role in rheumatoid arthritis susceptibility in Europe. European Consortium on Rheumatoid Arthritis Families
-
Barrera P, Balsa A, Alves H, et al. Noninherited maternal antigens do not play a role in rheumatoid arthritis susceptibility in Europe. European Consortium on Rheumatoid Arthritis Families. Arthritis Rheum 2000; 43:758-764.
-
(2000)
Arthritis Rheum
, vol.43
, pp. 758-764
-
-
Barrera, P.1
Balsa, A.2
Alves, H.3
-
44
-
-
0037241182
-
Noninherited maternal HLA alleles are associated with rheumatoid arthritis
-
Harney S, Newton J, Milicic A, et al. Noninherited maternal HLA alleles are associated with rheumatoid arthritis. Rheumatology (Oxford) 2003; 42:171-174.
-
(2003)
Rheumatology (Oxford)
, vol.42
, pp. 171-174
-
-
Harney, S.1
Newton, J.2
Milicic, A.3
-
45
-
-
0036381991
-
Nontransmitted maternal HLA DQ2 or DQ8 alleles and risk of Type I diabetes in offspring: The importance of foetal or post partum exposure to diabetogenic molecules
-
Pani MA, Van Autreve J, Van der Auwera BJ, et al. Nontransmitted maternal HLA DQ2 or DQ8 alleles and risk of Type I diabetes in offspring: the importance of foetal or post partum exposure to diabetogenic molecules. Diabetologia 2002; 45:1340-1343.
-
(2002)
Diabetologia
, vol.45
, pp. 1340-1343
-
-
Pani, M.A.1
Van Autreve, J.2
Van der Auwera, B.J.3
-
46
-
-
66749107783
-
-
Lambert AP, Gillespie KM, Bingley PJ, et al. -to: Pani MA, Van Autreve J, Van der Auwera BJ, Gorus FK, Badenhoop K. (2002) Nontransmitted maternal HLA DQ2 or DQ8 alleles and risk of Type 1 diabetes in offspring: the importance of foetal or post partum exposure to diabetogenic molecules. Diabetologia 45:1340-1343. Diabetologia 2003; 46:590-591.
-
Lambert AP, Gillespie KM, Bingley PJ, et al. -to: Pani MA, Van Autreve J, Van der Auwera BJ, Gorus FK, Badenhoop K. (2002) Nontransmitted maternal HLA DQ2 or DQ8 alleles and risk of Type 1 diabetes in offspring: the importance of foetal or post partum exposure to diabetogenic molecules. Diabetologia 45:1340-1343. Diabetologia 2003; 46:590-591.
-
-
-
-
47
-
-
0034516934
-
Chimerism in children with juvenile dermatomyositis
-
Reed AM, Picornell YJ, Harwood A, et al. Chimerism in children with juvenile dermatomyositis. Lancet 2000; 356:2156-2157.
-
(2000)
Lancet
, vol.356
, pp. 2156-2157
-
-
Reed, A.M.1
Picornell, Y.J.2
Harwood, A.3
-
48
-
-
1842529157
-
Does HLA-dependent chimerism underlie the pathogenesis of juvenile dermatomyositis?
-
Reed AM, McNallan K, Wettstein P, et al. Does HLA-dependent chimerism underlie the pathogenesis of juvenile dermatomyositis? J Immunol 2004; 172:5041-5046.
-
(2004)
J Immunol
, vol.172
, pp. 5041-5046
-
-
Reed, A.M.1
McNallan, K.2
Wettstein, P.3
-
49
-
-
0034509431
-
Chimeric cells of maternal origin in juvenile idiopathic inflammatory myopathies
-
Artlett CM, Ramos R, Jiminez SA, et al. Chimeric cells of maternal origin in juvenile idiopathic inflammatory myopathies. Lancet 2000; 356:2155-2156.
-
(2000)
Lancet
, vol.356
, pp. 2155-2156
-
-
Artlett, C.M.1
Ramos, R.2
Jiminez, S.A.3
-
50
-
-
0345714610
-
Myocardial-tissue- specific phenotype of maternal microchimerism in neonatal lupus congenital heart block
-
Stevens AM, Hermes HM, Rutledge JC, et al. Myocardial-tissue- specific phenotype of maternal microchimerism in neonatal lupus congenital heart block. Lancet 2003; 362:1617-1623.
-
(2003)
Lancet
, vol.362
, pp. 1617-1623
-
-
Stevens, A.M.1
Hermes, H.M.2
Rutledge, J.C.3
-
51
-
-
10444234973
-
Maternal microchimerism in the livers of patients with biliary atresia
-
Suskind DL, Rosenthal P, Heyman MB, et al. Maternal microchimerism in the livers of patients with biliary atresia. BMC Gastroenterol 2004; 4:14.
-
(2004)
BMC Gastroenterol
, vol.4
, pp. 14
-
-
Suskind, D.L.1
Rosenthal, P.2
Heyman, M.B.3
-
52
-
-
33846828821
-
Maternal microchimerism in peripheral blood in type 1 diabetes and pancreatic islet beta cell microchimerism
-
Nelson JL, Gillespie KM, Lambert NC, et al. Maternal microchimerism in peripheral blood in type 1 diabetes and pancreatic islet beta cell microchimerism. Proc Natl Acad Sci U S A 2007; 104:1637-1642.
-
(2007)
Proc Natl Acad Sci U S A
, vol.104
, pp. 1637-1642
-
-
Nelson, J.L.1
Gillespie, K.M.2
Lambert, N.C.3
-
54
-
-
0022929984
-
Preferential transmission of diabetic alleles within the HLA gene complex
-
Vadheim CM, Rotter JI, Maclaren NK, et al. Preferential transmission of diabetic alleles within the HLA gene complex. NEJM 1986; 315:1314-1318.
-
(1986)
NEJM
, vol.315
, pp. 1314-1318
-
-
Vadheim, C.M.1
Rotter, J.I.2
Maclaren, N.K.3
-
55
-
-
0031839419
-
The female X-inactivation mosaic in systemic lupus erythematosus
-
Stewart JJ. The female X-inactivation mosaic in systemic lupus erythematosus. Immunol Today 1998; 19:352-357.
-
(1998)
Immunol Today
, vol.19
, pp. 352-357
-
-
Stewart, J.J.1
-
56
-
-
33744936286
-
The epigenetic face of systemic lupus erythematosus
-
Ballestar E, Esteller M, Richardson BC. The epigenetic face of systemic lupus erythematosus. J Immunol 2006; 176:7143-7147.
-
(2006)
J Immunol
, vol.176
, pp. 7143-7147
-
-
Ballestar, E.1
Esteller, M.2
Richardson, B.C.3
-
57
-
-
33645082502
-
The role of X inactivation and cellular mosaicism in women's health and sex-specific diseases
-
Migeon BR. The role of X inactivation and cellular mosaicism in women's health and sex-specific diseases. JAMA 2006; 295:1428-1433.
-
(2006)
JAMA
, vol.295
, pp. 1428-1433
-
-
Migeon, B.R.1
-
58
-
-
38449116161
-
Demethylation of CD40LG on the inactive X in T cells from women with lupus
-
Elegant study suggesting that sex-specific DNA demethylation of an immunoregulatory locus in T cells contributes to SLE pathogenesis in adult females. This work opens a whole new field, the dysregulation of immunoregulatory genes on the inactive X chromosome in females, which may explain the female predominance of autoimmunity
-
Lu Q, Wu A, Tesmer L, et al. Demethylation of CD40LG on the inactive X in T cells from women with lupus. J Immunol 2007; 179:6352-6358. Elegant study suggesting that sex-specific DNA demethylation of an immunoregulatory locus in T cells contributes to SLE pathogenesis in adult females. This work opens a whole new field - the dysregulation of immunoregulatory genes on the inactive X chromosome in females - which may explain the female predominance of autoimmunity.
-
(2007)
J Immunol
, vol.179
, pp. 6352-6358
-
-
Lu, Q.1
Wu, A.2
Tesmer, L.3
-
59
-
-
35548965046
-
Immunological and genetic bases of new primary immunodeficiencies
-
Marodi L, Notarangelo LD. Immunological and genetic bases of new primary immunodeficiencies. Nat Rev Immunol 2007; 7:851-861.
-
(2007)
Nat Rev Immunol
, vol.7
, pp. 851-861
-
-
Marodi, L.1
Notarangelo, L.D.2
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