메뉴 건너뛰기




Volumn 45, Issue 2, 1997, Pages 193-202

Molecular modelling of HLA-DQ suggests a mechanism of resistance in type 1 diabetes

Author keywords

[No Author keywords available]

Indexed keywords

HLA DQ ANTIGEN; T LYMPHOCYTE RECEPTOR;

EID: 0031033610     PISSN: 03009475     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-3083.1997.d01-389.x     Document Type: Article
Times cited : (25)

References (44)
  • 1
    • 0019455384 scopus 로고
    • HLA-D and HLA-DR antigens in genetic analysis of insulin-dependent diabetes mellitus
    • Platz P, Jakobsen BK, Morling N et al. HLA-D and HLA-DR antigens in genetic analysis of insulin-dependent diabetes mellitus. Diabetologia 1981;21:1108-15.
    • (1981) Diabetologia , vol.21 , pp. 1108-1115
    • Platz, P.1    Jakobsen, B.K.2    Morling, N.3
  • 2
    • 0027933734 scopus 로고
    • A genome-wide search for human type 1 diabetes susceptibility genes
    • Davies JL, Kawaguchi Y, Bennett ST et al. A genome-wide search for human type 1 diabetes susceptibility genes. Nature 1994;371:130-6.
    • (1994) Nature , vol.371 , pp. 130-136
    • Davies, J.L.1    Kawaguchi, Y.2    Bennett, S.T.3
  • 3
    • 0002099569 scopus 로고
    • Insulin-dependent diabetes mellitus
    • Teraski PI, ed. Los Angeles: UCLA Press
    • Svejgaard A, Platz P, Ryder LP. Insulin-dependent diabetes mellitus. In: Teraski PI, ed. Histocompatibility Testing, 1980. Los Angeles: UCLA Press, 1980:638-56.
    • (1980) Histocompatibility Testing, 1980 , pp. 638-656
    • Svejgaard, A.1    Platz, P.2    Ryder, L.P.3
  • 4
    • 0018834488 scopus 로고
    • Linkage analysis between the major histocompatibility system and insulin dependent diabetes in families with patients in two consecutive generations
    • Barbosa J, Chern MM, Anderson VE et al. Linkage analysis between the major histocompatibility system and insulin dependent diabetes in families with patients in two consecutive generations. J Clin Invest 1980;65:592-601.
    • (1980) J Clin Invest , vol.65 , pp. 592-601
    • Barbosa, J.1    Chern, M.M.2    Anderson, V.E.3
  • 5
    • 0001412144 scopus 로고
    • Insulin-dependent diabetes mellitus
    • Albert ED, ed. Berlin, Heidelberg: Springer-Verlag
    • Bertrams J, Baur MP. Insulin-dependent diabetes mellitus. In: Albert ED, ed. Histocompatibility Testing, 1984. Berlin, Heidelberg: Springer-Verlag, 1984:346-58.
    • (1984) Histocompatibility Testing, 1984 , pp. 346-358
    • Bertrams, J.1    Baur, M.P.2
  • 6
    • 0029620427 scopus 로고
    • HLA-encoded susceptibility to insulin-dependent diabetes mellitus is determined by DR and DQ genes as well as their linkage disequilibria in a Chinese population
    • Huang H, Peng J, She JY et al. HLA-encoded susceptibility to insulin-dependent diabetes mellitus is determined by DR and DQ genes as well as their linkage disequilibria in a Chinese population. Hum Immunol 1995;44:210-9.
    • (1995) Hum Immunol , vol.44 , pp. 210-219
    • Huang, H.1    Peng, J.2    She, J.Y.3
  • 7
    • 0021879031 scopus 로고
    • Allelic polymorphism and transassociation of molecules encoded by the HLA-DQ subregion
    • Giles RC, Demars R, Chang CC, Capra JD. Allelic polymorphism and transassociation of molecules encoded by the HLA-DQ subregion. Proc Natl Acad Sci USA 1985;82:1776-80.
    • (1985) Proc Natl Acad Sci USA , vol.82 , pp. 1776-1780
    • Giles, R.C.1    Demars, R.2    Chang, C.C.3    Capra, J.D.4
  • 8
    • 0027298481 scopus 로고
    • HLA-DQ allelic polymorphisms constrain patterns of class II heterodimer formation
    • Kwok WW, Kovats S, Thurtle P, Nepom GT. HLA-DQ allelic polymorphisms constrain patterns of class II heterodimer formation. J Immunol 1993;150:2263-72.
    • (1993) J Immunol , vol.150 , pp. 2263-2272
    • Kwok, W.W.1    Kovats, S.2    Thurtle, P.3    Nepom, G.T.4
  • 9
    • 0029905302 scopus 로고    scopus 로고
    • Susceptibility to type I diabetes: HLA-DQ and DR revisted
    • She JX. Susceptibility to type I diabetes: HLA-DQ and DR revisted. Immunol Today 1996;17:323-9.
    • (1996) Immunol Today , vol.17 , pp. 323-329
    • She, J.X.1
  • 10
    • 0025331496 scopus 로고
    • Analysis of HLA-DQ genotypes and susceptibility in insulin-dependent diabetes mellitus
    • Baisch JM, Weeks T, Giles RC, Hoover ML, Stastny P, Capra JD. Analysis of HLA-DQ genotypes and susceptibility in insulin-dependent diabetes mellitus. N Engl J Med 1990;322:1836-41.
    • (1990) N Engl J Med , vol.322 , pp. 1836-1841
    • Baisch, J.M.1    Weeks, T.2    Giles, R.C.3    Hoover, M.L.4    Stastny, P.5    Capra, J.D.6
  • 12
    • 8044245027 scopus 로고
    • MHC-associated antigen processing, presentation, and recognition: Adolescence, maturity, and beyond
    • Germain RN. MHC-associated antigen processing, presentation, and recognition: adolescence, maturity, and beyond. Scand J Immunol 1995;36:321-30.
    • (1995) Scand J Immunol , vol.36 , pp. 321-330
    • Germain, R.N.1
  • 13
    • 0028348369 scopus 로고
    • Crystal structure of the human class II MHC protein HLA-DR1 complexed with an influenza virus peptide
    • Stern LJ, Brown JH, Jardetzky TS et al. Crystal structure of the human class II MHC protein HLA-DR1 complexed with an influenza virus peptide. Nature 1994;368:215-21.
    • (1994) Nature , vol.368 , pp. 215-221
    • Stern, L.J.1    Brown, J.H.2    Jardetzky, T.S.3
  • 14
    • 0022355071 scopus 로고
    • Restriction fragment length polymorphism of the gene encoding the alpha chain of the human T cell receptor
    • Hoover ML, Marks J, Chipman J, Palmer E, Stastny P, Capra JD. Restriction fragment length polymorphism of the gene encoding the alpha chain of the human T cell receptor. J Exp Med 1985;162:1087-92.
    • (1985) J Exp Med , vol.162 , pp. 1087-1092
    • Hoover, M.L.1    Marks, J.2    Chipman, J.3    Palmer, E.4    Stastny, P.5    Capra, J.D.6
  • 15
    • 0029284475 scopus 로고
    • HLA class II region nucleotide sequences
    • Marsh SG, Bodmer JG. HLA class II region nucleotide sequences. Eur J Immunogen 1995;22:225,526a-7b.
    • (1995) Eur J Immunogen , vol.22 , pp. 225
    • Marsh, S.G.1    Bodmer, J.G.2
  • 16
    • 0021107965 scopus 로고
    • Solvent-accessible surfaces of proteins and nucleic acids
    • Connolly ML. Solvent-accessible surfaces of proteins and nucleic acids. Science 1983;221:709-13.
    • (1983) Science , vol.221 , pp. 709-713
    • Connolly, M.L.1
  • 17
    • 0027217789 scopus 로고
    • Three-dimensional structure of the human class II histocompatibility antigen HLA-DR1
    • Brown JH, Jardetzky TS, Gorga JC et al. Three-dimensional structure of the human class II histocompatibility antigen HLA-DR1. Nature 1993;364:33-9.
    • (1993) Nature , vol.364 , pp. 33-39
    • Brown, J.H.1    Jardetzky, T.S.2    Gorga, J.C.3
  • 18
    • 0028823585 scopus 로고
    • The structure of an intermediate in class II MHC maturation - Clip bound to HLA-DR3
    • Ghosh P, Amaya M, Mellins E, Wiley DC. The structure of an intermediate in class II MHC maturation - clip bound to HLA-DR3. Nature 1995;378:457-62.
    • (1995) Nature , vol.378 , pp. 457-462
    • Ghosh, P.1    Amaya, M.2    Mellins, E.3    Wiley, D.C.4
  • 19
    • 0001330676 scopus 로고
    • HLA class II associations in insulin-dependent diabetes mellitus among Blacks, Caucasoids and Japanese
    • Sasazuki T, ed. Oxford: Oxford University Press
    • Ronningen KS, Spurkland A, Tait BD et al. HLA class II associations in insulin-dependent diabetes mellitus among Blacks, Caucasoids and Japanese. In: Sasazuki T, ed. HLA 1991. Oxford: Oxford University Press, 1993:713-22.
    • (1993) HLA 1991 , pp. 713-722
    • Ronningen, K.S.1    Spurkland, A.2    Tait, B.D.3
  • 20
    • 0025326199 scopus 로고
    • A combination of HLA-DQ beta Asp57-negative and HLA DQ alpha Arg52 confers susceptibility to insulin-dependent diabetes mellitus
    • Khalil I, d'Auriol L, Gobet M et al. A combination of HLA-DQ beta Asp57-negative and HLA DQ alpha Arg52 confers susceptibility to insulin-dependent diabetes mellitus. J Clin Invest 1990;85:1315-9.
    • (1990) J Clin Invest , vol.85 , pp. 1315-1319
    • Khalil, I.1    D'Auriol, L.2    Gobet, M.3
  • 21
    • 0025778297 scopus 로고
    • HLA-DQA1 and -DQB1 alleles associated with genetic susceptibility to IDDM in a black population
    • Mijovic CH, Jenkins D, Jacobs KH, Penny MA, Fletcher JA, Barnett AH. HLA-DQA1 and -DQB1 alleles associated with genetic susceptibility to IDDM in a black population. Diabetes 1991;40:748-53.
    • (1991) Diabetes , vol.40 , pp. 748-753
    • Mijovic, C.H.1    Jenkins, D.2    Jacobs, K.H.3    Penny, M.A.4    Fletcher, J.A.5    Barnett, A.H.6
  • 22
    • 0025138978 scopus 로고
    • High frequency of aspartic acid at position 57 of HLA-DQ beta-chain in Japanese IDDM patients and nondiabetic subjects
    • Awata T, Kuzuya T, Matsuda A et al. High frequency of aspartic acid at position 57 of HLA-DQ beta-chain in Japanese IDDM patients and nondiabetic subjects. Diabetes 1990;39:266-9.
    • (1990) Diabetes , vol.39 , pp. 266-269
    • Awata, T.1    Kuzuya, T.2    Matsuda, A.3
  • 23
    • 0026647948 scopus 로고
    • An explanation for the neutral effect of DR2 on IDDM susceptibility in central Italy
    • Sorrentino R, De Grazia U, Buzzetti R et al. An explanation for the neutral effect of DR2 on IDDM susceptibility in central Italy. Diabetes 1992;41:904-8.
    • (1992) Diabetes , vol.41 , pp. 904-908
    • Sorrentino, R.1    De Grazia, U.2    Buzzetti, R.3
  • 24
    • 0027237554 scopus 로고
    • Combinations of specific DRB1, DQA1, DQB1 haplotypes are associated with insulin-dependent diabetes mellitus in Sardinia
    • Cucca F, Muntoni F, Lampis R et al. Combinations of specific DRB1, DQA1, DQB1 haplotypes are associated with insulin-dependent diabetes mellitus in Sardinia. Hum Immunol 1993;37:85-94.
    • (1993) Hum Immunol , vol.37 , pp. 85-94
    • Cucca, F.1    Muntoni, F.2    Lampis, R.3
  • 25
    • 0028957706 scopus 로고
    • Effects of the second HLA-DQ haplotype on the association with childhood insulin-dependent diabetes mellitus
    • Sanjeevi CB, Landinolsson M, Kockum I, Dahlquist G, Lernmark A. Effects of the second HLA-DQ haplotype on the association with childhood insulin-dependent diabetes mellitus. Tissue Antigens 1995;45:148-52.
    • (1995) Tissue Antigens , vol.45 , pp. 148-152
    • Sanjeevi, C.B.1    Landinolsson, M.2    Kockum, I.3    Dahlquist, G.4    Lernmark, A.5
  • 26
    • 0027524412 scopus 로고
    • HLA class II alleles and susceptibility and resistance to insulin dependent diabetes mellitus in Mexican-American families
    • Erlich HA, Zeidler A, Chang J et al. HLA class II alleles and susceptibility and resistance to insulin dependent diabetes mellitus in Mexican-American families. Nature Genet 1993;3:358-64.
    • (1993) Nature Genet , vol.3 , pp. 358-364
    • Erlich, H.A.1    Zeidler, A.2    Chang, J.3
  • 27
    • 0001657878 scopus 로고
    • Aspartic acid at position 57 of the HLA-DQ beta chain protects against type I diabetes: A family study
    • Morel PA, Dorman JS, Todd JA, McDevitt HO, Trucco M. Aspartic acid at position 57 of the HLA-DQ beta chain protects against type I diabetes: a family study. Proc Natl Acad Sci USA 1988;85: 8111-5.
    • (1988) Proc Natl Acad Sci USA , vol.85 , pp. 8111-8115
    • Morel, P.A.1    Dorman, J.S.2    Todd, J.A.3    McDevitt, H.O.4    Trucco, M.5
  • 29
    • 0025012475 scopus 로고
    • The A3 allele of the HLA-DQA1 locus is associated with susceptibility to type 1 diabetes in Japanese
    • Todd JA, Fukui Y, Kitagawa T, Sasazuki T. The A3 allele of the HLA-DQA1 locus is associated with susceptibility to type 1 diabetes in Japanese. Proc Natl Acad Sci USA 1990;87:1094-8.
    • (1990) Proc Natl Acad Sci USA , vol.87 , pp. 1094-1098
    • Todd, J.A.1    Fukui, Y.2    Kitagawa, T.3    Sasazuki, T.4
  • 30
    • 0026591143 scopus 로고
    • An investigation of Japanese subjects maps susceptibility to type 1 (insulin-dependent) diabetes mellitus close to the DQA1 gene
    • Jacobs KH, Jenkins D, Mijovic C et al. An investigation of Japanese subjects maps susceptibility to type 1 (insulin-dependent) diabetes mellitus close to the DQA1 gene. Hum Immunol 1992;33:24-8.
    • (1992) Hum Immunol , vol.33 , pp. 24-28
    • Jacobs, K.H.1    Jenkins, D.2    Mijovic, C.3
  • 31
    • 0024438233 scopus 로고
    • The amino acid at position 57 of the HLA-DQ beta chain and susceptibility to develop insulin-dependent diabetes mellitus
    • Ronningen KS, Iwe T, Halstensen TS, Spurkland A, Thorsby E. The amino acid at position 57 of the HLA-DQ beta chain and susceptibility to develop insulin-dependent diabetes mellitus. Hum Immunol 1989;26:215-5.
    • (1989) Hum Immunol , vol.26 , pp. 215-215
    • Ronningen, K.S.1    Iwe, T.2    Halstensen, T.S.3    Spurkland, A.4    Thorsby, E.5
  • 32
    • 0027213991 scopus 로고
    • HLA-DQA1 and DQB1 gene polymorphisms in type I diabetic-patients from central Italy and their use for risk prediction
    • Buzzetti R, Nistico L, Osborn JF, Giovannini C, Chersi A, Sorrentino R. HLA-DQA1 and DQB1 gene polymorphisms in type I diabetic-patients from central Italy and their use for risk prediction. Diabetes 1993;42:1173-8.
    • (1993) Diabetes , vol.42 , pp. 1173-1178
    • Buzzetti, R.1    Nistico, L.2    Osborn, J.F.3    Giovannini, C.4    Chersi, A.5    Sorrentino, R.6
  • 33
    • 0027767584 scopus 로고
    • Association of insulin-dependent diabetes mellitus in Taiwan with HLA class II DQB1 and DRB1 alleles
    • Hu CY, Allen M, Chuang LM, Lin BJ, Gyllensten U. Association of insulin-dependent diabetes mellitus in Taiwan with HLA class II DQB1 and DRB1 alleles. Hum Immunol 1993;38:105-14.
    • (1993) Hum Immunol , vol.38 , pp. 105-114
    • Hu, C.Y.1    Allen, M.2    Chuang, L.M.3    Lin, B.J.4    Gyllensten, U.5
  • 34
    • 0025152043 scopus 로고
    • Worldwide differences in the incidence of type I diabetes are associated with amino acid variation at position 57 of the HLA-DQ beta chain
    • Dorman JS, LaPorte RE, Stone RA, Trucco M. Worldwide differences in the incidence of type I diabetes are associated with amino acid variation at position 57 of the HLA-DQ beta chain. Proc Natl Acad Sci USA 1990;87:7370-4.
    • (1990) Proc Natl Acad Sci USA , vol.87 , pp. 7370-7374
    • Dorman, J.S.1    LaPorte, R.E.2    Stone, R.A.3    Trucco, M.4
  • 35
    • 0026687104 scopus 로고
    • Distribution of HLA-DQA1, -DQB1 and DRB1 alleles in black IDDM patients and controls from Zimbabwe
    • Garcia-Pacheco JM, Herbut B, Cutbush S et al. Distribution of HLA-DQA1, -DQB1 and DRB1 alleles in black IDDM patients and controls from Zimbabwe. Tissue Antigens 1992;40:145-9.
    • (1992) Tissue Antigens , vol.40 , pp. 145-149
    • Garcia-Pacheco, J.M.1    Herbut, B.2    Cutbush, S.3
  • 36
    • 0027415719 scopus 로고
    • Genes for insulin-dependent diabetes mellitus (IDDM) in the major histocompatibility complex (MHC) of African-Americans
    • Fernandez-Vina M, Ramirez LC, Raskin P, Stastny P. Genes for insulin-dependent diabetes mellitus (IDDM) in the major histocompatibility complex (MHC) of African-Americans. Tissue Antigens 1993;41:57-64.
    • (1993) Tissue Antigens , vol.41 , pp. 57-64
    • Fernandez-Vina, M.1    Ramirez, L.C.2    Raskin, P.3    Stastny, P.4
  • 37
    • 0023936156 scopus 로고
    • A hypothetical model of the foreign antigen binding site of class II histocompatibility molecules
    • Brown JH, Jardetzky T, Saper MA, Samraoui B, Bjorkman PJ, Wiley DC. A hypothetical model of the foreign antigen binding site of class II histocompatibility molecules. Nature 1988;332:845-50.
    • (1988) Nature , vol.332 , pp. 845-850
    • Brown, J.H.1    Jardetzky, T.2    Saper, M.A.3    Samraoui, B.4    Bjorkman, P.J.5    Wiley, D.C.6
  • 38
    • 0029078319 scopus 로고
    • Accuracy of a structural homology model for a class II histocompatibility protein, HLA-DR1 - Comparison to the crystal structure
    • Nauss JL, Reid RH, Sadeghnasseri S. Accuracy of a structural homology model for a class II histocompatibility protein, HLA-DR1 - comparison to the crystal structure. J Biomol Struct Dyn 1995;12:1213-33.
    • (1995) J Biomol Struct Dyn , vol.12 , pp. 1213-1233
    • Nauss, J.L.1    Reid, R.H.2    Sadeghnasseri, S.3
  • 39
    • 0026434554 scopus 로고
    • Separation of IL-4 production from Th cell proliferation by an altered T cell receptor ligand
    • Evavold BD, Allen PM. Separation of IL-4 production from Th cell proliferation by an altered T cell receptor ligand. Science 1991;252:1308-10.
    • (1991) Science , vol.252 , pp. 1308-1310
    • Evavold, B.D.1    Allen, P.M.2
  • 40
    • 0023837985 scopus 로고
    • Self-tolerance eliminates T cells specific for MLS-modified products of the major histocompatibility complex
    • Kappler JW, Staerz U, White J, Marrack PC. Self-tolerance eliminates T cells specific for MLS-modified products of the major histocompatibility complex. Nature 1988;332:35-40.
    • (1988) Nature , vol.332 , pp. 35-40
    • Kappler, J.W.1    Staerz, U.2    White, J.3    Marrack, P.C.4
  • 41
    • 0023813094 scopus 로고
    • Thymic major histocompatibility complex antigens and the alpha beta T-cell receptor determine the CD4/CD8 phenotype of T cells
    • Teh HS, Kisielow P, Scott B et al. Thymic major histocompatibility complex antigens and the alpha beta T-cell receptor determine the CD4/CD8 phenotype of T cells. Nature 1988;335:229-33.
    • (1988) Nature , vol.335 , pp. 229-233
    • Teh, H.S.1    Kisielow, P.2    Scott, B.3
  • 42
    • 0023683669 scopus 로고
    • Positive selection of antigen-specific T cells in thymus by restricting MHC molecules
    • Kisielow P, Teh HS, Bluthmann H, von Boehmer H. Positive selection of antigen-specific T cells in thymus by restricting MHC molecules. Nature 1988;335:730-3.
    • (1988) Nature , vol.335 , pp. 730-733
    • Kisielow, P.1    Teh, H.S.2    Bluthmann, H.3    Von Boehmer, H.4
  • 43
    • 0026463035 scopus 로고
    • Selecting T cell receptors with high affinity for self-MHC by decreasing the contribution of CD8
    • Sherman LA, Hesse SV, Irwin MJ, La Face D, Peterson P. Selecting T cell receptors with high affinity for self-MHC by decreasing the contribution of CD8. Science 1992;258:815-8.
    • (1992) Science , vol.258 , pp. 815-818
    • Sherman, L.A.1    Hesse, S.V.2    Irwin, M.J.3    La Face, D.4    Peterson, P.5
  • 44
    • 0028935971 scopus 로고
    • The T cell receptor begins to reveal its many facets
    • Marx J. The T cell receptor begins to reveal its many facets. Science 1995;267:459-60.
    • (1995) Science , vol.267 , pp. 459-460
    • Marx, J.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.