HLA association with autoimmune disease: A failure to protect?

Rheumatology

Volumn 39, Issue 10, 2000, Pages 1060-1066

  Zanelli, E ^a   Breedveld, F C ^a   De Vries, R R P ^a  

^a LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

AUTOANTIGEN; CD3 ANTIGEN; CD4 ANTIGEN; HLA ANTIGEN; HLA ANTIGEN CLASS 2; HLA DQ ANTIGEN; HLA DR ANTIGEN; INTERLEUKIN 10; MAJOR HISTOCOMPATIBILITY ANTIGEN; TRANSFORMING GROWTH FACTOR BETA;

ALLELE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIBODY SPECIFICITY; ANTIGEN PRESENTATION; AUTOIMMUNE DISEASE; AUTOIMMUNITY; CELLULAR IMMUNITY; CONTROLLED STUDY; DISEASE PREDISPOSITION; HAPLOTYPE; HLA SYSTEM; HUMAN; IMMUNOREGULATION; LYMPHOCYTE FUNCTION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTECTION; RAT; REVIEW; RHEUMATOID ARTHRITIS; SYNOVIOCYTE; T LYMPHOCYTE;

EID: 0033782915     PISSN: 14620324     EISSN: None     Source Type: Journal    
DOI: 10.1093/rheumatology/39.10.1060     Document Type: Review

References (48)

1. The role of T cells in the immunopathogenesis of rheumatoid arthritis
2. Evidence for the role of an altered redox state in hyporesponsiveness of synovial T cells in rheumatoid arthritis
3. Monoclonal antibodies to CD4
4. Treatment with CD4 depleting monoclonal antibodies results in a preferential loss of circulating naive T cells but does not affect IFN gamma-secreting Th1 cells in humans
5. Invasive fibroblast-like synoviocytes in rheumatoid arthritis
6. Pathogenesis of joint damage in rheumatoid arthritis
7. IL-6 synthesis by rheumatoid synoviocytes is autonomously upregulated at the transcriptional level
8. Rheumatoid arthritis as a bone marrow disorder
9. Retroviral sequences in rheumatoid arthritis synovium
10. Human T cell leukemia virus type-I and rheumatoid arthritis
11. Inhibition of T cell apoptosis in the rheumatoid synovium
12. Fibroblast-like synoviocytes from rheumatoid arthritis patients have intrinsic properties of follicular dendritic cells
13. Citrulline is an essential constituent of antigenic determinants recognized by rheumatoid arthritis-specific autoantibodies
14. Failure to induce organ-specific autoimmunity by breaking of tolerance: Importance of the microenvironment
15. Murine lupus in the absence of alpha beta T cells
16. A new model of rheumatoid arthritis generated by engraftment of rheumatoid synovial tissue and normal human cartilage into SCID mice
17. Prevention of autoimmune inflammatory polyarthritis in male New Zealand Black/KN mice by transplantation of bone marrow cells plus bone (stromal cells)
18. Interleukin 10 secretion and impaired effector function of major histocompatibility complex class II-restricted T cells anergized in vivo
19. Peripheral autoantigen induces regulatory T cells that prevent autoimmunity
20. A CD4+ T-cell subset inhibits antigen-specific T-cell responses and prevents colitis
21. Do heat shock proteins control the balance of T-cell regulation in inflammatory diseases?
22. Induction and expression of human cartilage glycoprotein 39 in rheumatoid inflammatory and peripheral blood monocyte-derived macrophages
23. Specificity and promiscuity among naturally processed peptides bound to HLA-DR alleles
24. Could HLA-DRB1 be the protective locus in rheumatoid arthritis?
25. b molecules
26. Expression of the human leukocyte antigen DR3 transgene reduces the severity of demyelination in a murine model of multiple sclerosis
27. Spontaneous T cell proliferation in the non-obese diabetic mouse to a peptide from the unique class II MHC molecule, I-Ag7, which is also protective against the development of autoimmune diabetes
28. Evidence for the continuous recruitment and activation of T cells into the joints of patients with rheumatoid arthritis
29. Flow cytometry single-cell analysis of cytokine production by CD4+ T cells in synovial tissue and peripheral blood from patients with rheumatoid arthritis
30. IL-16 as an anti-inflammatory cytokine in rheumatoid arthritis
31. An extended HLA-DQ-DR haplotype rather than DRB1 alone contributes to RA predisposition
32. HLA-DQ-associated predisposition to and dominant HLA-DR-associated protection against rheumatoid arthritis
33. Paradoxical inheritance of HLA-linked susceptibility to rheumatoid arthritis
34. Relative predispositional effects and mode of inheritance of HLA-DRB1 alleles among community-based Caucasian females with rheumatoid arthritis
35. HLA-B27 can form a novel β2-microglobulin-free heavy chain homodimer structure
36. Strong association of HLA-DRB1*0301/x and DRB1*0101/0301 genotypes with sarcoid arthritis
37. D6S273 microsatellite polymorphism and susceptibility to rheumatoid arthritis
38. TNFa microsatellite polymorphism distinguishes HLA-DQ3DR4-positive rheumatoid arthritis patients from HLA-DQ3DR4-positive patients with other rheumatic diseases
39. TNFa microsatellite polymorphism modulates the risk of IDDM in Caucasians with the high risk genotype HLA-DQA1*0501-DQB1*0201/DQA1*0301-DQB1*0302. Belgian Diabetes Registry
40. Exceptional stability of the HLA-DQA1*0102/DQB1*0602 αβ protein dimer, the class II MHC molecule associated with protection from insulin-dependent diabetes mellitus
41. Differential expression of insulin-dependent diabetes mellitus-associated HLA-DQA1 alleles in vivo
42. TNF blockade in rheumatoid arthritis: Implications for therapy and pathogenesis
43. Interleukin 15: A proinflammatory role in rheumatoid arthritis synovitis
44. Could endogenous self-peptides presented by dendritic cells initiate rheumatoid arthritis?
45. High levels of a major histocompatibility complex II-self peptide complex on dendritic cells from the T cell areas of lymph nodes
46. The evolution of self-tolerance: A new cell arises to meet the challenge of self-reactivity
47. Deficient autologous mixed lymphocyte reactions correlate with disease activity in systemic lupus erythematosus and rheumatoid arthritis
48. Localization of quantitative trait loci regulating adjuvant-induced arthritis in rats: Evidence for genetic factors common to multiple autoimmune diseases