Structural and dynamic characterization of ω-conotoxin MVIIA: The binding loop exhibits slow conformational exchange

Biochemistry

Volumn 39, Issue 14, 2000, Pages 3908-3919

  Atkinson, R Andrew ^a,b   Kieffer, Bruno ^a   Dejaegere, Annick ^a   Sirockin, Finton ^a   Lefèvre, Jean François ^a  

^a UPR 9003 du CNRS   (France)

^b NATIONAL INSTITUTE FOR MEDICAL RESEARCH   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM CHANNEL; OMEGA CONOTOXIN;

ARTICLE; BINDING SITE; CONFORMATIONAL TRANSITION; MATHEMATICAL ANALYSIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN FOLDING; PROTEIN STRUCTURE; PROTON NUCLEAR MAGNETIC RESONANCE; REACTION ANALYSIS;

ANIMALS; MAGNETIC RESONANCE SPECTROSCOPY; OMEGA-CONOTOXINS; PROTEIN CONFORMATION; SNAILS;

CONUS MAGUS; GASTROPODA; INVERTEBRATA; LIPARIS (SCORPAENIFORM);

EID: 0034636131     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi992651h     Document Type: Article

References (73)

1. Olivera, B. M., Rivier, J., Clark, C., Ramilo, C. A., Corpuz, G. P., Abogadie, F. C., Mena, E. E., Woodward, S. R., Hillyard, D. R., and Cruz, L. J. (1990) Science 249, 257-263.
2. Olivera, B. M., Cruz, L. J., de Santos, V., LeCheminant, G. W., Griffin, D., Zeikus, R., McIntosh, J. M., Galyean, R., Varga, J., Gray, W. R., and Rivier, J. (1987) Biochemistry 26, 2086-2090.
3. Olivera, B. M., Miljanich, G. P., Ramachandran, J., and Adams, M. E. (1994) Annu. Rev. Biochem. 63, 823-867.
4. Myers, R. A., Cruz, L. J., Rivier, J. E., and Olivera, B. M. (1993) Chem. Rev. 93, 1923-1936.
5. Pallaghy, P. K., Duggan, B. M., Pennington, M. W., and Norton, R. S. (1993) J. Mol. Biol. 234, 405-420.
6. Sevilla, P., Bruix, M., Santoro, J., Gago, P., García, A. G., and Rico, M. (1993) Biochem. Biophys. Res. Commun. 192, 1238-1244.
7. Skalicky, J. J., Metzler, W. J., Ciesla, D. J., Galdes, A., and Pardi, A. (1993) Protein Sci. 2, 1591-1603.
8. Basus, V. J., Nadasdi, L., Ramachandran, J., and Miljanich, G. P. (1995) FEBS Lett. 370, 163-169.
9. Kohno, T., Kim, J. I., Kobayashi, K., Kodera, Y., Maeda, T., and Sato, K. (1995) Biochemistry 34, 10256-10265.
10. Farr-Jones, S., Miljanich, G. P., Nadasdi, L., Ramachandran, J., and Basus, V. J. (1995) J. Mol. Biol. 248, 106-124.
11. Nielsen, K. J., Thomas, L., Lewis, R. J., Alewood, P. F., and Craik, D. J. (1996) J. Mol. Biol. 263, 297-310.
12. Pallaghy, P. K., Nielsen, K. J., Craik, D. J., and Norton, R. S. (1994) Protein Sci. 3, 1833-1839.
13. Lampe, R. A., Lo, M. M. S., Keith, R. A., Horn, M. B., McLane, M. W., Herman, J. L., and Spreen, R. C. (1993) Biochemistry 32, 3255-3260.
14. Sato, K., Park, N.-G., Kohno, T., Maeda, T., Kim, J. I., Kato, R., and Takahashi, M. (1993) Biochem. Biophys. Res. Commun. 194, 1292-1296.
15. Nadasdi, L., Yamashiro, D., Chung, D., Tarczy-Hornoch, K., Adriaenssens, P., and Ramachandran, J. (1995) Biochemistry 34, 8076-8081.
16. Kim, J, I., Takahashi, M., Ogura, A., Kohno, T., Kudo, Y., and Sato, K. (1994) J. Biol. Chem. 269, 23876-23878.
17. Kim, J. I., Takahashi, M., Ohtake, A., Wakamiya, A., and Sato, K. (1995) Biochem. Biophys. Res. Commun. 206, 449-454.
18. Kim, J. I., Takahashi, M., Martin-Moutot, N., Seagar, M. J., Ohtake, A., and Sato, K. (1995) Biochem. Biophys. Res. Commun. 214, 305-309.
19. States, D. J., Haberkorn, R. A., and Ruben, D. J. (1982) J. Magn. Reson. 48, 286-292.
20. Marion, D., and Wüthrich, K. (1983) Biochem. Biophys. Res. Commun. 113, 961-914.
21. Aue, W. P., Bartholdi, E., and Ernst, R. R. (1976) J. Chem. Phys. 64, 2229-2246.
22. Braunschweiler, L., and Ernst, R. R. (1983) J. Magn. Reson. 53, 521-528.
23. Bax, A., and Davis, D. G. (1985) J. Magn. Reson. 65, 355-360.
24. Jeener, J., Meier, B. H., Bachmann, P., and Ernst, R. R. (1979) J. Chem. Phys. 71, 4546-4553.
25. Piotto, M., Saudek, V., and Sklenář, V. (1992) J. Biomol. NMR 2, 661-665.
26. Sklenář, V., Piotto, M., Leppik, R., and Saudek, V. (1993) J. Magn. Reson. Series A 102, 241-245.
27. Bodenhausen, G., and Ruben, D. J. (1980) Chem. Phys. Lett. 69, 185-189.
28. Cavanagh, J., Palmer, A. G., III, Wright, P. E., and Rance, M. (1991) J. Magn. Reson. 91, 429-436.
29. Shaka, A. J., Barker, P. B., and Freeman, R. (1985) J. Magn. Reson. 64, 547-552.
30. Dayie, K. T., and Wagner, G. (1994) J. Magn. Reson. Series A 111, 121-126.
31. Peng, J. W., and Wagner, G. (1992) J. Magn. Reson. 98, 308-332.
32. Peng, J. W., and Wagner, G. (1992) Biochemistry 31, 8571-8586.
33. Farrow, N, A., Zhang, O., Szabo, A., Torchia, D. A., and Kay, L. E. (1995) J. Biomol. NMR 6, 153-162.
34. Ishima, R., and Nagayama, K. (1995) J. Magn. Reson. Series B 108, 73-76.
35. Peng, J. W., and Wagner, G. (1995) Biochemistry 34, 16733-16752.
36. Lefèvre, J.-F., Dayie, K. T., Peng, J. W., and Wagner, G. (1996) Biochemistry 35, 2674-2686.
37. Ye, C., Fu, R., Hu, J., Hou, L., and Ding, S. (1993) Magn. Reson. Chem. 31, 699-704.
38. Atkinson, R. A., and Lefèvre, J.-F. (1999) J. Biomol. NMR 13, 83-88.
39. Kirkpatrick, S., Gelatt, C. D., Jr., and Vecchi, M. P. (1983) Science 220, 671-680.
40. Goffe, W. L., Ferner, G. D., and Rogers, J. (1994) J. Econometrics 60, 65-99.
41. Martin, J. F., Selwyn, L. S., Vold, R. R., and Void, R. L. (1982) J. Chem. Phys. 76, 2632-2634.
42. Zax, D. B., and Pines, A. (1983) J. Chem. Phys. 78, 6333-6334.
43. Kay, L. E., and Prestegard, J. H. (1986) J. Magn. Reson. 67, 103-113.
44. Stejskal, E. O., and Tanner, J. E. (1965) J. Chem. Phys. 42, 288-292.
45. Wüthrich, K., Billeter, M., and Braun, W. (1983) J. Mol. Biol. 180, 949-961.
46. Karplus, M. (1959) J. Chem. Phys. 30, 11-15.
47. Pardi, A., Billeter, M., and Wüthrich, K. (1984) J. Mol. Biol. 180, 741-751.
48. Ludvigsen, S., and Poulsen, F. M. (1992) J. Biomol. NMR 2, 227-233.
49. Wagner, G., Braun, W., Havel, T. F., Schaumann, T., Gō, N., and Wüthrich, K. (1987) J. Mol. Biol. 196, 611-639.
50. Brünger, A. (1992) X-PLOR Software Manual, version 3.1, Yale University Press, New Haven, CT.
51. Ösapay, K., and Case, D. A. (1991) J. Am. Chem. Soc. 113, 9436-9444.
52. Merutka, G., Dyson, H. J., and Wright, P. E. (1995) J. Biomol. NMR 5, 14-24.
53. Ösapay, K., and Case, D. A. (1994) J. Biomol. NMR 4, 215-230.
54. Sitkoff, D., and Case, D. A. (1997) J. Am. Chem. Soc. 119, 12262-12273.
55. Wüthrich, K. (1986) NMR of Proteins and Nucleic Acids, J. Wiley, New York, .
56. Pastore, A., and Saudek, V. (1990) J. Magn. Reson. 90, 165-176.
57. Wishart, D. S., Sykes, B. D., and Richards, F. M. (1991) J. Mol. Biol. 222, 311-333.
58. Wishart, D. S., Sykes, B. D., and Richards, F. M. (1992) Biochemistry 31, 1647-1651.
59. Baxter, N. J., and Williamson, M. P. (1997) J. Biomol. NMR 9, 359-369.
60. Dubin, S. B., Clarck, N. A., and Benedeck, G. B. (1971) J. Chem. Phys. 54, 5158-5164.
61. Altieri, A. S., Hinton, D. P., and Byrd, R. A. (1995) J. Am. Chem. Soc. 117, 7566-7567.
62. Williamson, M. P., Kikuchi, J., and Asakura, T. (1995) J. Mol. Biol. 247, 541-546.
63. Mer, G., Dejaegere, A., Stote, R., Kieffer, B., and Lefèvre, J.-F. (1996) J. Chem. Phys. 100, 2667-2674.
64. Beeser, S. A., Oas, T. G., and Goldenberg, D. P. (1998) J. Mol. Biol. 284, 1581-1596.
65. Civera, C., Vásquez, A., Sevilla, J. M., Bruix, M., Gago, F., Garcia, A. G., and Sevilla, P. (1999) Biochem. Biophys. Res. Commun. 254, 32-35.
66. Gouda, H., and Hirono, S. (1999) Biochim. Biophys. Acta 1431, 384-394.
67. Maslennikov, I. V., Shenkarev, Z. O., Zhmak, M. N., Ivanov, V. T., Methfessel, C., Tsetlin, V. I., and Arseniev, A. S. (1999) FEBS Lett. 444, 275-280.
68. Rogers, J. P., Luginbühl, P., Shen, G. S., McCabe, R. T., Stevens, R. C., and Wemmer, D. E. (1999) Biochemistry 38, 3874-3882.
69. Hill, J. M., Oomen, C. J., Miranda, L. P., Bingham, J.-P., Alewood, P. F., and Craik, D. J. (1998) Biochemistry 37, 15621-15630.
70. Gray, W. R., Rivier, J. E., Galyean, R., Cruz, L. J., and Olivera, B. M. (1983) J. Biol. Chem. 258, 12247-12251.
71. Gouda, H., Yamazaki, K., Hasegawa, J., Kobayashi, Y., Nishiuchi, Y., Sakakibara, S., and Hirono, S. (1997) Biochim. Biophys. Acta 1343, 327-334.
72. Maslennikov, I. V., Sobol, A. G., Gladky, K. V., Lugovskoy, A. A., Ostrovsky, A. G., Tsetlin, V. I., Ivanov, V. T., and Arseniev, A. S. (1998) Eur. J. Biochem. 254, 238-247.
73. Wikström, A., Berglund, H., Hanbraeus, C., van der Berg, S., and Härd, T. (1999) J. Mol. Biol. 289, 963-979.