메뉴 건너뛰기




Volumn 133, Issue 44, 2008, Pages 2277-2282

Recent studies on nitrates: Their action, bioactivation and development of tolerance;Neue erkenntnisse bei der nitratwirkung, nitratbioaktivierung und toleranzentwicklung

Author keywords

Coronary heart disease; Drug tolerance; Nitrates; Nitric oxide; Nitroglycerin; Pentaerythretyl tetranitrate

Indexed keywords

GLYCERYL TRINITRATE; ISOSORBIDE; MOLSIDOMINE; NITRIC ACID DERIVATIVE; PENTAERYTHRITYL TETRANITRATE; ALDEHYDE DEHYDROGENASE; ALDH2 PROTEIN, HUMAN; DRUG DERIVATIVE; GUANYLATE CYCLASE; HYDRALAZINE; ISOSORBIDE 5 NITRATE; ISOSORBIDE DINITRATE; ISOSORBIDE-5-MONONITRATE; NITRATE; NITRIC OXIDE; NITRIC OXIDE DONOR; REACTIVE OXYGEN METABOLITE; VASODILATOR AGENT;

EID: 54849414292     PISSN: 00120472     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-0028-1091272     Document Type: Review
Times cited : (15)

References (32)
  • 1
    • 0023412369 scopus 로고
    • Glyceryl trinitrate (nitroglycerin) and the organic nitrates. Choosing the method of administration
    • Abrams J. Glyceryl trinitrate (nitroglycerin) and the organic nitrates. Choosing the method of administration. Drugs 1987; 34: 391-403
    • (1987) Drugs , vol.34 , pp. 391-403
    • Abrams, J.1
  • 2
    • 33845883560 scopus 로고    scopus 로고
    • Influence of blood pressure on the effectiveness of a fixed-dose combination of isosorbide dinitrate and hydralazine in the African-American Heart Failure Trial
    • Anand IS, Tam SW, Rector TS et al. Influence of blood pressure on the effectiveness of a fixed-dose combination of isosorbide dinitrate and hydralazine in the African-American Heart Failure Trial. J Am Coll Cardiol 2007; 49: 32-39
    • (2007) J Am Coll Cardiol , vol.49 , pp. 32-39
    • Anand, I.S.1    Tam, S.W.2    Rector, T.S.3
  • 3
    • 0035133327 scopus 로고    scopus 로고
    • Azevedo ER, Schofield AM, Kelly S, Parker JD. Nitroglycerin withdrawal increases endothelium-dependent vasomotor response to acetylcholine. J Am Coll Cardiol 2001; 37: 505-509
    • Azevedo ER, Schofield AM, Kelly S, Parker JD. Nitroglycerin withdrawal increases endothelium-dependent vasomotor response to acetylcholine. J Am Coll Cardiol 2001; 37: 505-509
  • 4
    • 0032420985 scopus 로고    scopus 로고
    • Therapy with nitroglycerin increases coronary vasoconstriction in response to acetylcholine
    • Caramori PR, Adelman AG, Azevedo ER et al. Therapy with nitroglycerin increases coronary vasoconstriction in response to acetylcholine. J Am Coll Cardiol 1998; 32: 1969-1974
    • (1998) J Am Coll Cardiol , vol.32 , pp. 1969-1974
    • Caramori, P.R.1    Adelman, A.G.2    Azevedo, E.R.3
  • 5
    • 0037062518 scopus 로고    scopus 로고
    • Identification of the enzymatic mechanism of nitroglycerin bioactivation
    • Chen Z, Zhang J, Stamler JS. Identification of the enzymatic mechanism of nitroglycerin bioactivation. Proc Natl Acad Sci U S A 2002; 99: 8306-8311
    • (2002) Proc Natl Acad Sci U S A , vol.99 , pp. 8306-8311
    • Chen, Z.1    Zhang, J.2    Stamler, J.S.3
  • 6
    • 0022623381 scopus 로고
    • Effect of vasodilator therapy on mortality in chronic congestive heart failure. Results of a Veterans Administration Cooperative Study
    • Cohn JN, Archibald DC, Ziesche S et al. Effect of vasodilator therapy on mortality in chronic congestive heart failure. Results of a Veterans Administration Cooperative Study. The New England journal of medicine 1986; 314: 1547-1552
    • (1986) The New England journal of medicine , vol.314 , pp. 1547-1552
    • Cohn, J.N.1    Archibald, D.C.2    Ziesche, S.3
  • 7
    • 0025770138 scopus 로고
    • A comparison of enalapril with hydralazine-isosorbide dinitrate in the treatment of chronic congestive heart failure
    • Cohn JN, Johnson G, Ziesche S et al. A comparison of enalapril with hydralazine-isosorbide dinitrate in the treatment of chronic congestive heart failure. The New England journal of medicine 1991; 325: 303-310
    • (1991) The New England journal of medicine , vol.325 , pp. 303-310
    • Cohn, J.N.1    Johnson, G.2    Ziesche, S.3
  • 8
    • 27844580204 scopus 로고    scopus 로고
    • Hydralazine is a powerful inhibitor of peroxynitrite formation as a possible explanation forks beneficial effects on prognosis in patients with congestive heart failure
    • Daiber A, Oelze M, Coldewey M et al. Hydralazine is a powerful inhibitor of peroxynitrite formation as a possible explanation forks beneficial effects on prognosis in patients with congestive heart failure. Biochem Biophys Res Commun 2005; 338: 1865-1874
    • (2005) Biochem Biophys Res Commun , vol.338 , pp. 1865-1874
    • Daiber, A.1    Oelze, M.2    Coldewey, M.3
  • 9
    • 9444221430 scopus 로고    scopus 로고
    • Oxidative stress and mitochondrial aldehyde dehydrogenase activity: A comparison of pentaerythritol tetranitrate with other organic nitrates
    • Daiber A, Oelze M, Coldewey M et al. Oxidative stress and mitochondrial aldehyde dehydrogenase activity: a comparison of pentaerythritol tetranitrate with other organic nitrates. Mol Pharmacol 2004; 66: 1372-1382
    • (2004) Mol Pharmacol , vol.66 , pp. 1372-1382
    • Daiber, A.1    Oelze, M.2    Coldewey, M.3
  • 10
    • 33750930318 scopus 로고    scopus 로고
    • Complex 1 dysfunction and tolerance to nitroglycerin: An approach based on mitochondrial-targeted antioxidants
    • Esplugues JV, Rocha M, Nunez C et al. Complex 1 dysfunction and tolerance to nitroglycerin: an approach based on mitochondrial-targeted antioxidants. Circ Res 2006; 99: 1067-1075
    • (2006) Circ Res , vol.99 , pp. 1067-1075
    • Esplugues, J.V.1    Rocha, M.2    Nunez, C.3
  • 11
    • 0017836883 scopus 로고
    • Nitrate effects on cardiac output and left ventricular outflow resistance in chronic congestive heart failure
    • Franciosa JA Blank RC, Cohn JN. Nitrate effects on cardiac output and left ventricular outflow resistance in chronic congestive heart failure. Am J Med 1978; 64: 207-213
    • (1978) Am J Med , vol.64 , pp. 207-213
    • Franciosa, J.A.1    Blank, R.C.2    Cohn, J.N.3
  • 12
    • 0017882832 scopus 로고
    • Hemodynamic responsiveness to short- and long-acting vasodilators in left ventricular failure
    • Franciosa JA, Cohn JN. Hemodynamic responsiveness to short- and long-acting vasodilators in left ventricular failure. Am J Med 1978; 65: 126-133
    • (1978) Am J Med , vol.65 , pp. 126-133
    • Franciosa, J.A.1    Cohn, J.N.2
  • 13
    • 0028784929 scopus 로고
    • Prevention of tolerance to hemodynamic effects of nitrates with concomitant use of hydralazine in patients with chronic heart failure
    • Gogia H, Mehra A, Parikh S et al. Prevention of tolerance to hemodynamic effects of nitrates with concomitant use of hydralazine in patients with chronic heart failure. J Am Coll Cardiol 1995; 26: 1575-1580
    • (1995) J Am Coll Cardiol , vol.26 , pp. 1575-1580
    • Gogia, H.1    Mehra, A.2    Parikh, S.3
  • 14
    • 0035806914 scopus 로고    scopus 로고
    • Folic acid prevents nitroglycerin-induced nitric oxide synthase dysfunction and nitrate tolerance: A human in vivo study
    • Gori T, Burstein JM, Ahmed S et al. Folic acid prevents nitroglycerin-induced nitric oxide synthase dysfunction and nitrate tolerance: a human in vivo study. Circulation 2001; 104: 1119-1123
    • (2001) Circulation , vol.104 , pp. 1119-1123
    • Gori, T.1    Burstein, J.M.2    Ahmed, S.3
  • 15
    • 0034805427 scopus 로고    scopus 로고
    • Evidence supporting abnormalities in nitric oxide synthase function induced by nitroglycerin in humans
    • Gori T, Mak SS, Kelly S, Parker JD. Evidence supporting abnormalities in nitric oxide synthase function induced by nitroglycerin in humans. J Am Coll Cardiol 2001; 38: 1096-1101
    • (2001) J Am Coll Cardiol , vol.38 , pp. 1096-1101
    • Gori, T.1    Mak, S.S.2    Kelly, S.3    Parker, J.D.4
  • 16
    • 0035960677 scopus 로고    scopus 로고
    • Endothelial dysfunction, oxidative stress, and risk of cardiovascular events in patients with coronary artery disease
    • Heitzer T, Schlinzig T, Krohn K, Meinertz T, Munzel T. Endothelial dysfunction, oxidative stress, and risk of cardiovascular events in patients with coronary artery disease. Circulation 2001; 104: 2673-2678
    • (2001) Circulation , vol.104 , pp. 2673-2678
    • Heitzer, T.1    Schlinzig, T.2    Krohn, K.3    Meinertz, T.4    Munzel, T.5
  • 17
    • 10744223291 scopus 로고    scopus 로고
    • Role for peroxynitrite in the inhibition of prostacyclin synthase in nitrate tolerance
    • Hink U, Oelze M, Kolb P et al. Role for peroxynitrite in the inhibition of prostacyclin synthase in nitrate tolerance. J Am Coll Cardiol 2003; 42: 1826-1834
    • (2003) J Am Coll Cardiol , vol.42 , pp. 1826-1834
    • Hink, U.1    Oelze, M.2    Kolb, P.3
  • 18
    • 0034846916 scopus 로고    scopus 로고
    • Differential effects of pentaerythritol tetranitrate and nitroglycerin on the development of tolerance and evidence of lipid peroxidation: A human in vivo study
    • Jurt U, Gori T, Ravandi A et al. Differential effects of pentaerythritol tetranitrate and nitroglycerin on the development of tolerance and evidence of lipid peroxidation: a human in vivo study. J Am Coll Cardiol 2001; 38: 854-859
    • (2001) J Am Coll Cardiol , vol.38 , pp. 854-859
    • Jurt, U.1    Gori, T.2    Ravandi, A.3
  • 19
    • 0038604446 scopus 로고    scopus 로고
    • Interactions of peroxynitrite, tetrahydrobiopterin, ascorbic acid, and thiols: Implications for uncoupling endothelial nitric-oxide synthase
    • Kuzkaya N, Weissmann N, Harrison DG, Dikalov S. Interactions of peroxynitrite, tetrahydrobiopterin, ascorbic acid, and thiols: implications for uncoupling endothelial nitric-oxide synthase. J Biol Chem 2003; 278: 22546-22554
    • (2003) J Biol Chem , vol.278 , pp. 22546-22554
    • Kuzkaya, N.1    Weissmann, N.2    Harrison, D.G.3    Dikalov, S.4
  • 20
    • 26244465889 scopus 로고    scopus 로고
    • Explaining the phenomenon of nitrate tolerance
    • Munzel T, Daiber A, Mulsch A. Explaining the phenomenon of nitrate tolerance. Circ Res 2005; 97: 618-628
    • (2005) Circ Res , vol.97 , pp. 618-628
    • Munzel, T.1    Daiber, A.2    Mulsch, A.3
  • 21
    • 0242330206 scopus 로고    scopus 로고
    • Physiology and pathophysiology of vascular signaling controlled by guanosine 3′,5′-cyclic monophosphate-dependent protein kinase [corrected]
    • Munzel T, Feil R, Mulsch A et al. Physiology and pathophysiology of vascular signaling controlled by guanosine 3′,5′-cyclic monophosphate-dependent protein kinase [corrected]. Circulation 2003; 108: 2172-2183
    • (2003) Circulation , vol.108 , pp. 2172-2183
    • Munzel, T.1    Feil, R.2    Mulsch, A.3
  • 22
  • 23
    • 17144447936 scopus 로고    scopus 로고
    • Dissociation of coronary vascular tolerance and neurohormonal adjustments during long-term nitroglycerin therapy in patients with stable coronary artery disease
    • Munzel T, Heitzer T, Kurz S et al. Dissociation of coronary vascular tolerance and neurohormonal adjustments during long-term nitroglycerin therapy in patients with stable coronary artery disease. J Am Coll Cardiol 1996; 27: 297-303
    • (1996) J Am Coll Cardiol , vol.27 , pp. 297-303
    • Munzel, T.1    Heitzer, T.2    Kurz, S.3
  • 24
    • 0028799761 scopus 로고
    • Evidence for enhanced vascular superoxide anion production in nitrate tolerance. A novel mechanism underlying tolerance and cross-tolerance
    • Munzel T, Sayegh H, Freeman BA, Tarpey MM, Harrison DG. Evidence for enhanced vascular superoxide anion production in nitrate tolerance. A novel mechanism underlying tolerance and cross-tolerance. J Clin Invest 1995; 95: 187-194
    • (1995) J Clin Invest , vol.95 , pp. 187-194
    • Munzel, T.1    Sayegh, H.2    Freeman, B.A.3    Tarpey, M.M.4    Harrison, D.G.5
  • 25
    • 0038545209 scopus 로고    scopus 로고
    • Endothelial protection by pentaerithrityl trinitrate: Bilirubin and carbon monoxide as possible mediators
    • Oberle S, Abate A, Grosser N et al. Endothelial protection by pentaerithrityl trinitrate: bilirubin and carbon monoxide as possible mediators. Exp Biol Med (Maywood) 2003; 228: 529-534
    • (2003) Exp Biol Med (Maywood) , vol.228 , pp. 529-534
    • Oberle, S.1    Abate, A.2    Grosser, N.3
  • 26
    • 0032101741 scopus 로고    scopus 로고
    • Defective smooth muscle regulation in cGMP kinase I-deficient mice
    • Pfeifer A, Klatt P, Massberg S et al. Defective smooth muscle regulation in cGMP kinase I-deficient mice. Embo J 1998; 17: 3045-3051
    • (1998) Embo J , vol.17 , pp. 3045-3051
    • Pfeifer, A.1    Klatt, P.2    Massberg, S.3
  • 27
    • 0025373475 scopus 로고
    • Nitrates: Why and how should they be used today? Current status of the clinical usefulness of nitroglycerin, isosorbide dinitrate and isosorbide-5-mononitrate
    • Silber S. Nitrates: why and how should they be used today? Current status of the clinical usefulness of nitroglycerin, isosorbide dinitrate and isosorbide-5-mononitrate. Eur J Clin Pharmacol 1990; 38 Suppl 1: S35-51
    • (1990) Eur J Clin Pharmacol , vol.38 , Issue.SUPPL. 1
    • Silber, S.1
  • 28
    • 19644400578 scopus 로고    scopus 로고
    • Combination of isosorbide dinitrate and hydralazine in blacks with heart failure
    • Taylor AL, Ziesche S, Yancy C et al. Combination of isosorbide dinitrate and hydralazine in blacks with heart failure. The New England journal of medicine 2004; 351: 2049-2057
    • (2004) The New England journal of medicine , vol.351 , pp. 2049-2057
    • Taylor, A.L.1    Ziesche, S.2    Yancy, C.3
  • 29
    • 33947501974 scopus 로고    scopus 로고
    • Once daily therapy with isosorbide-5-mononitrate causes endothelial dysfunction in humans: Evidence of a free-radical-mediated mechanism
    • Thomas GR, DiFabio JM, Gori T, Parker JD. Once daily therapy with isosorbide-5-mononitrate causes endothelial dysfunction in humans: evidence of a free-radical-mediated mechanism. J Am Coll Cardiol 2007; 49: 1289-1295
    • (2007) J Am Coll Cardiol , vol.49 , pp. 1289-1295
    • Thomas, G.R.1    DiFabio, J.M.2    Gori, T.3    Parker, J.D.4
  • 31
    • 33847152178 scopus 로고    scopus 로고
    • Number of nitrate groups determines reactivity and potency of organic nitrates: A proof of concept study in ALDH-2-/- mice
    • Wenzel P, Hink U, Oelze M et al. Number of nitrate groups determines reactivity and potency of organic nitrates: a proof of concept study in ALDH-2-/- mice. Br J Pharmacol 2007; 150: 526-533
    • (2007) Br J Pharmacol , vol.150 , pp. 526-533
    • Wenzel, P.1    Hink, U.2    Oelze, M.3
  • 32
    • 34547636112 scopus 로고    scopus 로고
    • Heme oxygenase-1: A novel key player in the development of tolerance in response to organic nitrates
    • Wenzel P, Oelze M, Coldewey M et al. Heme oxygenase-1: a novel key player in the development of tolerance in response to organic nitrates. Arterioscler Thromb Vasc Biol 2007; 27: 1729-1735
    • (2007) Arterioscler Thromb Vasc Biol , vol.27 , pp. 1729-1735
    • Wenzel, P.1    Oelze, M.2    Coldewey, M.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.