Alcohol induces DNA damage and the fanconi anemia D2 protein implicating FANCD2 in the DNA damage response pathways in brain

Alcoholism: Clinical and Experimental Research

Volumn 32, Issue 7, 2008, Pages 1186-1196

  Rulten, S L ^a,b   Hodder, E ^a   Ripley, T L ^a   Stephens, D N ^a   Mayne, L V ^a  

^a UNIVERSITY OF SUSSEX   (United Kingdom)

^b UNIVERSITY OF SUSSEX   (United Kingdom)

Author keywords

Brain; DNA Damage Responses; DNA Strand Breaks; Ethanol; Fanconi Anemia

Indexed keywords

ACETALDEHYDE; ALCOHOL; DNA; FANCONI ANEMIA GROUP D2 PROTEIN; MESSENGER RNA; RNA; THYMIDINE; URIDINE; CENTRAL DEPRESSANT AGENT; FANCD2 PROTEIN, MOUSE; H2AFX PROTEIN, HUMAN; HISTONE;

ANIMAL TISSUE; ARTICLE; BRAIN DAMAGE; BRAIN FUNCTION; CELL DIVISION; CELL STRAIN; COMET ASSAY; CONTROLLED STUDY; DNA DAMAGE; DNA STRAND BREAKAGE; DNA SYNTHESIS; FANCONI ANEMIA; GENETIC TRANSCRIPTION; HUMAN; HUMAN CELL; IMMUNOCYTOCHEMISTRY; IN VIVO STUDY; MESENCEPHALON; MOUSE; NERVE CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; PROTEIN FUNCTION; PROTEIN TRANSPORT; REAL TIME POLYMERASE CHAIN REACTION; RNA SYNTHESIS; UBIQUITINATION; WESTERN BLOTTING; ANIMAL; BIOSYNTHESIS; BRAIN; C57BL MOUSE; CELL LINE; CELL NUCLEUS; DRINKING BEHAVIOR; DRUG EFFECT; MALE; METABOLISM;

ACETALDEHYDE; ALCOHOL DRINKING; ANIMALS; BRAIN; CELL LINE; CELL NUCLEUS; CENTRAL NERVOUS SYSTEM DEPRESSANTS; DNA; DNA DAMAGE; ETHANOL; FANCONI ANEMIA COMPLEMENTATION GROUP D2 PROTEIN; HISTONES; HUMANS; MALE; MICE; MICE, INBRED C57BL; RNA;

EID: 54749144646     PISSN: 01456008     EISSN: 15300277     Source Type: Journal    
DOI: 10.1111/j.1530-0277.2008.00673.x     Document Type: Article

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