Adrenomedullin in vascular diseases

Current Hypertension Reports

Volumn 6, Issue 1, 2004, Pages 55-59

  Ando, Katsuyuki ^a   Shimosawa, Tatsuo ^a   Fujita, Toshiro ^a  

^a UNIVERSITY OF TOKYO   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOVIRUS VECTOR; ADRENOMEDULLIN; ADRENOMEDULLIN RECEPTOR; ANGIOTENSIN; CALCITONIN GENE RELATED PEPTIDE RECEPTOR; ENDOTHELIAL NITRIC OXIDE SYNTHASE; INDUCIBLE NITRIC OXIDE SYNTHASE; NITRIC OXIDE; PROADRENOMEDULLIN; PROTECTIVE AGENT; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; TEMPOL; VASODILATOR AGENT; XANTHINE OXIDASE;

ANTIOXIDANT ACTIVITY; ARTICLE; AUTOCRINE EFFECT; CARDIOVASCULAR DISEASE; CORONARY ARTERY DISEASE; ENZYME INHIBITION; GENE DELIVERY SYSTEM; GENE EXPRESSION; GENE TRANSFER; HUMAN; HYPOXIA; INSULIN RESISTANCE; KNOCKOUT MOUSE; LUNG BLOOD VESSEL; MOUSE; NEGATIVE FEEDBACK; NONHUMAN; OXIDATIVE STRESS; PARACRINE SIGNALING; PATHOGENESIS; RAT; SALT LOADING;

EID: 5444255235     PISSN: 15226417     EISSN: None     Source Type: Journal    
DOI: 10.1007/s11906-004-0012-x     Document Type: Article

References (47)

1. Kitamura K, Kangawa K, Kawamoto M, et al.: Adrenomedullin: a novel hypotensive peptide isolated from human pheochromocytoma. Biochem Biophys Res Commun 1993, 192:553-560.
2. Shimosawa T, Ito Y, Ando K, et al.: Proadrenomedullin NH2-terminal 20 peptide, a new product of the adrenomedullin gene, inhibits norepinephrine overflow from nerve endings. J Clin Invest 1995, 96:1672-1676.
3. Isumi Y, Shoji H, Sugo S, et al.: Regulation of adrenomedullin production in rat endothelial cells. Endocrinology 1998, 139:38-46.
4. Sugo S, Minamino N, Shoji H, et al.: Production and secretion of adrenomedullin from vascular smooth muscle cells: augmented production by tumor necrosis factor. Biochem Biophys Res Comm 1994, 203:719-726.
5. Tsuruda T, Kato J, Kitamura K, et al.: Adrenomedullin: a possible autocrine and paracrine inhibitor of hypertrophy of cardiomyocytes. Hypertension 1998, 31:505-510.
6. Jougasaki M, Wei C-M, McKineley LJ, et al.: Elevation of circulating and ventricular adrenomedullin in human congestive heart failure. Circulation 1995, 92:286-289.
7. Ishimitsu T, Nishikimi T, Sato Y, et al.: Plasma levels of adrenomedullin, a newly identified hypotensive peptide, in patients with hypertension and renal failure. J Clin Invest 1994, 94:158-161.
8. Shimosawa T, Kanozawa K, Nagasawa R, et al.: Adrenomedullin amidation enzyme activities in hypertensive patients. Hypertens Res 2000, 23:167-172.
9. Kuriyama S, Kobayashi H, Tomonari H, et al.: Circulating adrenomedullin in erythropoietin-induced hypertension. Hypertens Res 2000, 23:427-432.
10. Kawai J, Ando K, Shimosawa T, et al.: Regional hemodynamic effects of adrenomedullin in Wistar rats: a comparison with calcitonin gene-related peptide. Hypertens Res 2002, 25: 441-446.
11. Kohno M, Yasunari K, Minami M, et al.: Regulation of rat mesangial cell migration by platelet-derived growth factor, angiotensin II, and adrenomedullin. J Am Soc Nephrol 1999, 10:2495-2502.
12. Kato H, Shichiri M, Marumo F, et al.: Adrenomedullin as an autocrine/paracrine apoptosis survival factor for rat endothelial cells. Endocrinology 1997, 138:2615-2620.
13. Yamasaki M, Kawai J, Nakaoka T, et al.: Adrenomedullin overexpression to limit arterial intimal formation induced by cuff placement. Hypertension 2003, 41:302-307.
14. Agata J, Zhang JJ, Chao J, et al.: Adrenomedullin gene delivery inhibits neointima formation in rat artery after balloon angioplasty. Regul Pept 2003, 112:115-120.
15. Imai Y, Shindo T, Maemura K, et al.: Resistance to neointimal hyperplasia and fatty streak formation in mice with adrenomedullin overexpression. Arterioscler Thromb Vasc Biol 2002, 22:1310-1315.
16. Shimosawa T, Matsui H, Xing G, et al.: Organ-protective effects of adrenomedullin. Hypertens Res 2003, 26(Suppl):S109-S112.
17. Ando K, Fujita T: Lessons from the adrenomedullin knockout mice. Regul Pept 2003, 112:185-188.
18. McLatchie LM, Fraser NJ, Main MJ, et al.: RAMPs regulate the transport and ligand specificity of the calcitonin-receptor-like receptor. Nature 1998, 393: 333-339.
19. Shimizu K, Tanaka H, Sunamori M, et al.: Adrenomedullin receptor antagonism by calcitonin gene-related peptide (8-37) inhibits carotid artery neointimal hyperplasia after balloon injury. Circ Res 1999, 85:1199-1205.
20. Kitamura K, Sakata J, Kangawa K, et al.: Cloning and characterization of cDNA encoding a precursor for human adrenomedullin. Biochem Biophys Res Comm 1993, 194:720-725.
21. Okazaki T, Ogawa Y, Tamura N, et al.: Genomic organization, expression, and chromosomal mapping of the mouse adrenomedullin gene. Genomics 1996, 37:395-399.
22. Shimosawa T, Fujita T: Hypotensive effect of newly identified peptide, proadrenomedullin N-terminal 20 peptide. Hypertension 1996, 28:325-329.
23. Ando K, Omi N, Shimosawa T, et al.: Proadrenomedullin N-terminal 20 peptide (PAMP) inhibits proliferation of human neuroblastoma TGW cells. FEBS Lett 1997, 413: 462-466.
24. Caron KM, Smithies O: Extreme hydrops fetus and cardiovascular abnormalities in mice lacking a functional adrenomedullin gene. Proc Natl Acad U S A 2001, 98:615-619.
25. Shindo T, Kurihara Y, Nishimatsu H, et al.: Vascular abnormalities and elevated blood pressure in mice lacking adrenomedullin gene. Circulation 2001, 104:1964-1971.
26. Shimosawa T, Shibagaki Y, Ishibashi K, et al.: Adrenomedullin, an endogenous peptide, counteracts cardiovascular damage. Circulation 2002, 105:106-111.
27. Cvetkovic B, Sigmund CD: Understanding hypertension through genetic manipulation in mice. Kidney Int 2000, 57:863-874.
28. Ando K, Sato Y, Fujita T: Salt sensitivity in hypertensive rats with angiotensin II administration. Am J Physiol 1990, 259:R1012-R1016.
29. Luft FC, Mervaala E, Muller DN, et al.: Hypertension-induced end-organ damage: a new transgenic approach to an old problem. Hypertension 1999, 33:212-218.
30. Rajagopalan S, Kurz S, Munzel T, et al.: Angiotensin II-mediated hypertension in the rats increases vascular superoxide production via membrane NADH/NADPH oxidase activation: contribution to alterations of vasomotor tone. J Clin Invest 1996, 97: 1916-1923.
31. Ando K, Ito Y, Kumada M, et al.: Oxidative stress increases adrenomedullin mRNA levels in cultured rat vascular smooth muscle cells. Hypertens Res 1998, 21:187-191.
32. Chini E, Chini C, Bolliger C, et al.: Cytoprotective effects of adrenomedullin in glomerular cell injury: central role of cAMP signaling pathway. Kidney Int 1997, 52:917-925.
33. Nishimatsu H, Hirata Y, Shindo T, et al.: Role of endogenous adrenomedullin in the regulation of vascular tone and ischemic renal injury: studies on transgenic/knockout mice of adrenomedullin gene. Circ Res 2002, 90:657-663.
34. Kawai S, Ando K, Tojo, A, et al.: Endogenous adrenomedullin protects against vascular response to injury in mice. Circulation, In press.
35. Kano H, Kohno M, Yasunari K, et al.: Adrenomedullin as a novel anti-proliferative factor of vascular smooth muscle cells. J Hypertens 1996, 14:209-213.
36. Kohno M, Yokokawa K, Kano H, et al.: Adrenomedullin is a potent inhibitor of angiotensin II-induced migration of human coronary artery smooth muscle cells. Hypertension 1997, 29: 1309-1313.
37. Griendling KK, Minieri CA, Ollerenshaw JD, et al.: Angiotensin II stimulates NADH and NADPH oxidase activity in cultured vascular smooth muscle cells. Circ Res 1994, 74:1141-1148.
38. Wang HD, Xu S, Johns DG, et al.: Role of NADPH oxidase in the vascular hypertrophic and oxidative stress response to angiotensin II in mice. Circ Res 2001, 88:947-953.
39. Kato K, Yin H, Agata J, et al.: Adrenomedullin gene transfer attenuates myocardial infarction and apoptosis after ischemia and reperfusion. Am J Physiol Heart Circ Physiol 2003, 285: H1506-H1514.
40. Ikeda U, Kanbe T, Shimada K, et al.: Adrenomedullin increases inducible nitric oxide synthase in rat vascular smooth muscle cells stimulated with interleukin-1. Hypertension 1996, 27: 1240-1244.
41. Hattori Y, Nakanishi N, Gross SS, et al.: Adrenomedullin augments nitric oxide and tetrahydrobiopterin synthesis in cytokine-stimulated vascular smooth muscle cells. Cardiovasc Res 1999, 44:207-214.
42. Garg UC, Hassid A: Nitric oxide-generating vasodilators and 8-bromo-cyclic guanosine monophosphate inhibit mitogenesis and proliferation of cultured rat vascular smooth muscle cells. J Clin Invest 1989, 83:1774-1777.
43. Nakaki T, Nakayama M, Kato R: Inhibition by nitric oxide and nitric oxide-producing vasodilators of DNA synthesis in vascular smooth muscle cells. Eur J Pharmacol 1990, 189: 347-353.
44. Ogihara T, Asano T, Ando K, et al.: Angiotensin II-induced insulin resistance is associated with enhanced insulin signaling. Hypertension 2002, 40:672-679.
45. Rudich A, Kozlovsky N, Potashnik R, et al.: Oxidant stress reduces insulin responsiveness in 3T3-L1 adipocytes. Am J Physiol 1997, 272:E935-E940.
46. Tirosh A, Potashnik R, Bashan A, Rudich A: Oxidant stress disrupts insulin-induced cellular redistribution of insulin receptor substrate-1 and phosphatidylinositol 3-kinase in 3T3-L1 adipocytes: a putative cellular mechanism for impaired protein kinase B activation and GLUT4 translocation. J Biol Chem 1999, 274: 10595-10602.
47. Shimosawa T, Ogihara T, Matsui H, et al.: Deficiency of adrenomedullin induces insulin resistance by increasing oxidative stress. Hypertension 2003, 41:1080-1085.