Adrenomedullin: A Possible Autocrine or Paracrine Inhibitor of Hypertrophy of Cardiomyocytes

Hypertension

Volumn 31, Issue 1, 1998, Pages 505-510

  Tsuruda, Toshihiro ^a   Kato, Johji ^a   Kitamura, Kazuo ^a   Kuwasako, Kenji ^a   Imamura, Takuroh ^a   Koiwaya, Yasushi ^a   Tsuji, Tetsuo ^a   Kangawa, Kenji ^a   Eto, Tanenao ^a  

^a UNIVERSITY OF MIYAZAKI   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ADRENOMEDULLIN; ADRENOMEDULLIN (22 52); ADRENOMEDULLIN (22-52); ANGIOTENSIN II; BOVINE SERUM ALBUMIN; CALCITONIN GENE RELATED PEPTIDE; CALCITONIN GENE RELATED PEPTIDE (8 37); CALCITONIN GENE-RELATED PEPTIDE (8-37); MESSENGER RNA; PEPTIDE; PEPTIDE FRAGMENT; PHENYLALANINE; ANGIOTENSIN; CALCITONIN GENE RELATED PEPTIDE RECEPTOR; CALCITONIN GENE RELATED PEPTIDE[8-37];

ANIMAL; ARTICLE; BIOSYNTHESIS; CATTLE; CELL CULTURE; CULTURE MEDIUM; DRUG EFFECT; GENETIC TRANSCRIPTION; HEART; HEART MUSCLE; HUMAN; HYPERTROPHY; KINETICS; METABOLISM; NEWBORN; PATHOLOGY; RAT; WISTAR RAT; ANIMAL CELL; CONTROLLED STUDY; GROWTH INHIBITION; HEART CELL CULTURE; HEART VENTRICLE HYPERTROPHY; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN SECRETION; SIGNAL TRANSDUCTION;

ADRENOMEDULLIN; ANGIOTENSIN II; ANIMALS; ANIMALS, NEWBORN; CALCITONIN GENE-RELATED PEPTIDE; CATTLE; CELLS, CULTURED; CULTURE MEDIA, SERUM-FREE; HEART; HUMANS; HYPERTROPHY; KINETICS; MYOCARDIUM; PEPTIDE FRAGMENTS; PEPTIDES; PHENYLALANINE; RATS; RATS, WISTAR; RNA, MESSENGER; SERUM ALBUMIN, BOVINE; TRANSCRIPTION, GENETIC;

EID: 0031613014     PISSN: 0194911X     EISSN: 15244563     Source Type: Journal    
DOI: 10.1161/01.HYP.31.1.505     Document Type: Article

References (35)

1. Zak R. Cell proliferation during cardiac growth. Am J Cardiol. 1973;31:211-219.
2. Komuro I, Katoh Y, Kaida T, Shibazaki Y, Kurabayashi M, Hoh E, Takaku F, Yazaki Y. Mechanical loading stimulates cell hypertrophy and specific gene expression in cultured rat cardiac myocytes. J Biol Chem. 1991;266:1265-1268.
3. Simpson P. Norepinephrine-stimulated hypertrophy of cultured rat myocardial cells is an alpha 1 adrenergic response. J Clin Invest. 1983;72:732-738.
4. Sadoshima J, Izumo S. Molecular characterization of angiotensin II-induced hypertrophy of cardiac myocytes and hyperplasia of cardiac fibroblasts: critical role of the AT1 receptor subtype. Circ Res. 1993;73:413-423.
5. Kitamura K, Kangawa K, Kawamoto M, Ichiki Y, Nakamura S, Matsuo H, Eto T. Adrenomedullin: a novel hypotensive peptide isolated from human pheochromocytoma. Biochem Biophys Res Commun. 1993;192:553-560.
6. Ebara T, Miura K, Okumura M, Matsuura T, Kim S, Yukimura T, Iwao H. Effect of adrenomedullin on renal hemodynamics and functions in dogs. Eur J Pharmacol. 1994;263:69-73.
7. Yamaguchi T, Baba K, Doi Y, Yano K, Kitamura K, Eto T. Inhibition of aldosterone production by adrenomedullin, a hypotensive peptide, in the rat. Hypertension. 1996;28:308-314.
8. Kano H, Kohno M, Yasunari K, Yokokawa K, Horio T, Ikeda M, Minami M, Hanehira T, Takeda T, Yoshikawa J. Adrenomedullin as a novel antiproliferative factor of vascular smooth muscle cells. J Hypertens. 1996;14:209-213.
9. Ichiki Y, Kitamura K, Kangawa K, Kawamoto M, Matsuo H, Eto T. Distribution and characterization of immunoreactive adrenomedullin in human tissue and plasma. FEBS Lett. 1994;338:6-10.
10. Sakata J, Simokubo T, Kitamura K, Nishizono M, Ichiki Y, Kangawa K, Matsuo H, Eto T. Distribution and characterization of immunoreactive rat adrenomedullin in tissue and plasma. FEBS Lett. 1994;352:105-108.
11. Ishimitsu T, Nishikimi T, Saito Y, Kitamura K, Eto T, Kangawa K, Matsuo H, Omae T, Matsuoka H. Plasma levels of adrenomedullin, a newly identified hypotensive peptide, in patients with hypertension and renal failure. J Clin Invest. 1994;94:2158-2161.
12. Kato J, Kitamura K, Kuwasako K, Tanaka M, Ishiyama Y, Shimokubo T, Ichiki Y, Nakamura S, Kangawa K, Eto T, Plasma adrenomedullin in patients with primary aldosteronism. Am J Hypertens. 1995;8:997-1000.
13. Sakata J, Shimokubo T, Kitamura K, Nakamura S, Kangawa K, Matsuo H, Eto T. Molecular cloning and biological activities of rat adrenomedullin, a hypotensive peptide. Biochem Biophys Res Commun. 1993;195:921-927.
14. Kitamura K, Sakata J, Kangawa K, Kojima M, Matsuo H, Eto T. Cloning and characterization of cDNA encoding a precursor for human adrenomedullin. Biochem Biophys Res Commun. 1993;194:720-725.
15. Shimokubo T, Sakata J, Kitamura K, Kangawa K, Matsuo H, Eto T. Adrenomedullin: changes in circulating and cardiac tissue concentration in Dahl salt-sensitive rats on a high-salt diet. Clin Exp Hypertens, 1996;18:949-961.
16. Ishiyama Y, Kitamura K, Kato J, Sakata J, Kangawa K, Eto T. Changes in cardiac adrenomedullin concentration in renovascular hypertensive rats. Hypertens Res. 1997;20:113-117.
17. Simpson P, Savion S. Differentiation of rat myocytes in single cell cultures with and without proliferating nonmyocardial cells. Circ Res. 1982;50:101-116.
18. Sadoshima J, Jahn L, Takahashi T, Kulik TJ, Izumo S. Molecular characterization of the stretch-induced adaptation of cultured cardiac cells: an in vitro model of load-induced cardiac hypertrophy. J Biol Chem. 1992;267:10551-10560.
19. Galfre G, Milstein C. Preparation of monoclonal antibodies: strategies and procedures. Methods Enzymol. 1981;73:3-46.
20. Chiba T, Yamaguchi A, Yamatani T, Nakamura A, Morishita T, Inui T, Fukase M, Noda T, Fujita T. Calcitonin gene-related peptide receptor antagonist human CGRP(8-37). Am J Physiol. 1989;256:E331-E335.
21. Eguchi S, Hirata Y, Iwasaki H, Sato K, Watanabe TX, Inui T, Nakajima K, Sakakibara S, Marumo F. Structure-activity relationship of adrenomedullin, a novel vasodilatory peptide, in cultured rat vascular smooth muscle cells. Endocrinology 1994;135:2454-2458.
22. Ishihara T, Kato J, Kitamura K, Katoh F, Fujimoto S, Kangawa K, Eto T. Production of adrenomedullin in human vascular endothelial cells. Life Sci. 1997;60:1763-1769.
23. Sugo S, Minamino N, Shoji H, Kangawa K, Kitamura K, Eto T, Matsuo H. Production and secretion of adrenomedullin from vascular smooth muscle cells: augmented production by tumor necrosis factor-alpha. Biochem Biophys Res Commun. 1994;203:719-726.
24. Dahlof B, Pennert K, Hansson L. Reversal of left ventricular hypertrophy in hypertensive patients: a metaanalysis of 109 treatment studies. Am J Hypertens. 1992;5:95-110.
25. Sato A, Canny BJ, Autelitano DJ. Adrenomedullin stimulates cAMP accumulation and inhibits atrial natriuretic peptide gene expression in cardiomyocytes. Biochem Biophys Res Commun, 1997;230:311 314.
26. Ikenouchi H, Kangawa K, Matsuo H, Hirata Y. Negative inotropic effect of adrenomedullin in isolated adult rabbit cardiac ventricular myocytes. Circulation. 1997;95:2318-2324.
27. Nuki C, Kawasaki H, Kitamura K, Takenaga M, Kangawa K, Eto T, Wada A. Vasodilator effect of adrenomedullin and calcitonin gene-related peptide receptors in rat mesenteric vascular beds. Biochem Biophys Res Commun 1993;196:245-251.
28. 1 receptors. Life Sci. 1995;56:19-25.
29. Nandha KA, Taylor GM, Smith DM, Owji AA, Byfield PGH, Ghatei MA, Bloom SR. Specific adrenomedullin binding sites and hypotension in the rat systemic vascular bed. Regul Pept. 1996:62:145-151.
30. Kato J, Kitamura K, Kangawa K, Eto T. Receptors for adrenomedullin in human vascular endothelial cells. Eur J Pharmacol. 1995;289:383-385.
31. Champion HC, Santiago JA, Murphy WA, Coy DH, Kadowitz PJ. Adrenomedullin-(22-52) antagonizes vasodilator responses to CGRP but not adrenomedullin in the cat. Am J Physiol. 1997:272:R234-R242.
32. Kapas S, Catt KJ, Clark AJL. Cloning and expression of cDNA encoding a rat adrenomedullin receptor. J Biol Chem. 1995:270:25344-25347.
33. Aiyar N, Rand K, Elshourbagy NA, Zeng Z, Adamou JE, Bergsma DJ, Li Y. A cDNA encoding the calcitonin gene-related peptide type 1 receptor. J Biol Chem. 1996;271:11325-11329.
34. Muff R, Born W, Fischer JA. Calcitonin, calcitonin gene-related peptide, adrenomedullin and amylin: homologous peptides, separate receptors and overlapping biological actions. Eur J Endocrinol. 1995;133:17-20.
35. Kapas S. Clark AJL. Identification of an orphan receptor gene as a type 1 calcitonin gene-related peptide receptor. Biochem Biophys Res Commun. 1995;217:832-838.