Lessons from the adrenomedullin knockout mouse

Regulatory Peptides

Volumn 112, Issue 1-3, 2003, Pages 185-188

  Ando, Katsuyuki ^a   Fujita, Toshiro ^a  

^a UNIVERSITY OF TOKYO   (Japan)

Author keywords

Adrenomedullin; Angiotensin II; Cardiovascular system; Cuff placement; Hypertension; Salt

Indexed keywords

ADRENOMEDULLIN; ANGIOTENSIN; SODIUM CHLORIDE;

ANIMAL EXPERIMENT; ARTERY INTIMA PROLIFERATION; BLOOD VESSEL INJURY; CORONARY BLOOD VESSEL; FEMORAL ARTERY; HEART LEFT VENTRICLE; HEART VENTRICLE HYPERTROPHY; KNOCKOUT MOUSE; MOUSE; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; REVIEW;

EID: 0037445801     PISSN: 01670115     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0167-0115(03)00038-7     Document Type: Review

References (37)

1. Kitamura K., Kangawa K., Kawamoto M., Ichiki Y., Nakamura S., Matsuo H.et al. Adrenomedullin: a novel hypotensive peptide isolated from human pheochromocytoma. Biochem. Biophys. Res. Comm. 192:1993;553-560.
2. Isumi Y., Shoji H., Sugo S., Tochimoto T., Yoshioka M., Kangawa K.et al. Regulation of adrenomedullin production in rat endothelial cells. Endocrinology. 139:1998;838-846.
3. Sugo S., Minamino N., Shoji H., Kangawa K., Kitamura K., Eto T.et al. Production and secretion of adrenomedullin from vascular smooth muscle cells: augumented production by tumor necrosis factor. Biochem. Biophys. Res. Comm. 203:1994;719-726.
4. Tsuruda T., Kato J., Kitamura K., Kuwasako K., Imamura T., Koiwaya Y.et al. Adrenomedullin: a possible autocrine and paracrine inhibitor of hypertrophy of cardiomyocytes. Hypertension. 31:1998;505-510.
5. Jougasaki M., Wei C.-M., McKinley L.J., Burnett J.C. Jr. Elevation of circulating and ventricular adrenomedullin in human congestive heart failure. Circulation. 92:1995;286-289.
6. Ishimitsu T., Nishikimi T., Sato Y., Kitamura K., Eto T., Kangawa K.et al. Plasma levels of adrenomedullin, a newly identified hypotensive peptide, in patients with hypertension and renal failure. J. Clin. Invest. 94:1994;2158-2161.
7. Shimosawa T., Kanozawa K., Nagasawa R., Mitarai T., Isoda K., Takahashi K.et al. Adrenomedullin amidation enzyme activities in hypertensive patients. Hypertens. Res. 23:2000;167-172.
8. Kuriyama S., Kobayashi H., Tomonari H., Tokudome G., Hayashi F., Kaguchi Y.et al. Circulating adrenomedullin in erythropoietin-induced hypertension. Hypertens. Res. 23:2000;427-432.
9. Kano H., Kohno M., Yasunari K., Yokokawa K., Horio T., Ikeda M.et al. Adrenomedullin as a novel antiproliferative factor of vascular smooth muscle cells. J. Hypertens. 14:1996;209-213.
10. Horio T., Kohno M., Kano M., Ikeda M., Yasunari K., Yokokawa K.et al. Adrenomedullin as a novel antimigration factor of vascular smooth muscle cells. Circ. Res. 77:1995;660-664.
11. Kato H., Shichiri M., Marumo F., Hirata Y. Adrenomedullin as an autocrine/paracrine apoptosis survival factor for rat endothelial cells. Endocrinology. 138:1997;2615-2620.
12. Isumi Y., Minamino N., Kubo A., Nishimoto N., Yoshizaki K., Yoshioka M.et al. Adrenomedullin stimulates interleukin-6 production in Swiss 3T3 cells. Biochem. Biophys. Res. Comm. 244:1998;325-331.
13. Miller M.J., Martinez A., Unsworth E.J., Thiele C.J., Moody T.W., Elsasser Tet al. Adrenomedullin expression in human tumor cell lines. Its potential role as an autocrine growth factor. J. Biol. Chem. 271:1996;23345-23351.
14. Kitamura K., Sakata J., Kangawa K., Kojima M., Matsuo H., Eto T. Cloning and characterization of cDNA encoding a precursor for human adrenomedullin. Biochem. Biophys. Res. Comm. 194:1993;720-725.
15. Okazaki T., Ogawa Y., Tamura N., Mori K., Isse N., Aoki T.et al. Genomic organization, expression, and chromosomal mapping of the mouse adrenomedullin gene. Genomics. 37:1996;395-399.
16. Kitamura K., Kangawa K., Ishiyama Y., Washimine H., Ichiki Y., Kawamoto M.et al. Identification and hypotensive activity of preadrenomedullin N-terminal 20 peptide (PAMP). FEBS Lett. 351:1994;35-37.
17. 2-terminal 20 peptide, a new product of the adrenomedullin gene, inhibits norepinephrine overflow from nerve endings. J. Clin. Invest. 96:1995;1672-1676.
18. Shimosawa T., Fujita T. Hypotensive effect of newly identified peptide, proadrenomedullin N-terminal 20 peptide. Hypertension. 28:1996;325-329.
19. Ando K., Omi N., Shimosawa T., Fujita T. Proadrenomedullin N-terminal 20 peptide (PAMP) inhibits proliferation of human neuroblastoma TGW cells. FEBS Lett. 413:1997;462-466.
20. Caron K.M., Smithies O. Extreme hydrops fetalis and cardiovascular abnormalities in mice laking a functional adrenomedullin gene. Proc. Natl. Acad. Sci. U. S. A. 98:2001;615-619.
21. Shindo T., Kurihara Y., Nishimatsu H., Moriyama N., Kakoki M., Wang Y.et al. Vascular abnormalities and elevated blood pressure in mice laking adrenomedullin gene. Circulation. 104:2001;1964-1971.
22. Shimosawa T., Shibagaki Y., Ishibashi K., Kitamura K., Kangawa K., Kato S.et al. Adrenomedullin, an endogenous peptide, counteracts cardiovascular damages. Circulation. 105:2002;106-111.
23. Cvetkovic B., Sigmund C.D. Understanding hypertension through genetic manipulation in mice. Kidney Int. 57:2000;863-874.
24. Ando K., Sato Y., Fujita T. Salt sensitiviy in hypertensive rats with angiotensin II administration. Am. J. Physiol. 259:1990;R1012-R1016.
25. Luft F.C., Mervaala E., Muller D.N., Gross V., Schmidt F., Park J.K.et al. Hypertension-induced end-organ damage: a new transgenic approach to an old problem. Hypertension. 33:1999;212-218.
26. Rajagopalan S., Kurz S., Munzel T., Tarpey M., Freeman B.A., Griendling K.K.et al. Angiotensin II-mediated hypertension in the rat increases vascular superoxide production via membrane NADH/NADPH oxidase activation: contribution to alterations of vasomotor tone. J. Clin. Invest. 97:1996;1916-1923.
27. Fukai T., Siegfried M.R., Ushio-Fukai M., Griendling K.K., Harrison D.G. Modulation of extracellular superoxide dismutase expression by angiotensin II and hypertension. Circ. Res. 85:1999;23-28.
28. Usui M., Egashira K., Tomita H., Koyanagi M., Katoh M., Shimokawa H.et al. Important role of local angiotensin II activity mediated via type 1 receptor in the pathogenesis of cardiovascular inflammatory changes induced by chronic blockade of nitric oxide synthase in rats. Circulation. 101:2000;305-310.
29. Chini E., Chini C., Bolliger C., Jougasaki M., Grande J.P., Burnett J.C. Jr.et al. Cytoprotective effects of adrenomedullin in glomerular cell injury: central role of cAMP signaling pathway. Kidney Int. 52:1997;917-925.
30. Toyokuni S., Tanaka T., Hattori Y., Nishiyama Y., Yoshida A., Uchida K.et al. Quantitative immunohistochemical determination of 8-hydroxy-2′-deoxyguanosine by a monoclonal antibody N45.1: its application to ferric nitrilotriacetate-induced renal carcinogenesis model. Lab. Invest. 76:1997;365-374.
31. Morrow J.D., Frei B., Longmire A.W., Gaziano J.M., Lynch S.M., Shyr Y.et al. Increase in circulating products of lipid peroxidation (F2-isoprostanes) in smokers: smoking as a cause of oxidative damage. N. Engl. J. Med. 332:1995;1198-1203.
32. Ando K., Ito Y., Kumada M., Fujita T. Oxidative stress increases adrenomedullin mRNA levels in cultured rat vascular smooth muscle cells. Hypertens. Res. 21:1998;187-191.
33. Hirosumi J., Nomoto H., Ohkubo Y., Sekiguchi C., Mutoh S., Yamaguchi I.et al. Inflammatory responses in cuff-induced atherosclerosis in rabbits. Atherosclerosis. 64:1987;243-254.
34. De Meyer G.R., Van Put D.J., Kockx M.M., Van Schil P., Bosmans R., Bult H.et al. Possible mechanisms of collar-induced intimal thickning. Arterioscler. Thromb. Vasc. Biol. 17:1997;1924-1930.
35. Perlman H., Maillard L., Krasinski K., Walsh R. Evidence for the rapid onset of apoptosis in medial smooth muscle cells after ballon injury. Circulation. 95:1997;981-987.
36. Walsh K., Smith R.C., Kim H.S. Vascular cell apoptosis in remodeling, restenosis, and plaque rupture. Circ. Res. 87:2000;184-188.
37. Sata M., Kakoki M., Nagata D., Nishimatsuo H., Suzuki E., Aoyagi T.et al. Adrenomedullin and nitric oxide inhibit human endothelial cell apoptosis via a cyclic GMP-independent mechsanism. Hypertension. 36:2000;83-88.