Early cannabis use and DSM-IV nicotine dependence: A twin study

Addiction

Volumn 103, Issue 11, 2008, Pages 1896-1904

  Agrawal, Arpana ^a   Lynskey, Michael T ^a   Pergadia, Michele L ^a   Bucholz, Kathleen K ^a   Heath, Andrew C ^a   Martin, Nicholas G ^b   Madden, Pamela A F ^a  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b QIMR BERGHOFER MEDICAL RESEARCH INSTITUTE   (Australia)

Author keywords

Cannabis; Discordant twins; Genetic; Mx; Nicotine dependence; Twin modeling

Indexed keywords

CANNABIS; NICOTINE;

ADOLESCENT; ADULT; ARTICLE; CANNABIS ADDICTION; CIGARETTE SMOKING; CLINICAL STUDY; CONTROLLED STUDY; DIAGNOSTIC AND STATISTICAL MANUAL OF MENTAL DISORDERS; DISEASE ASSOCIATION; ENVIRONMENTAL FACTOR; FEMALE; HEREDITY; HUMAN; MALE; TOBACCO DEPENDENCE;

ADULT; AUSTRALIA; DISEASES IN TWINS; FEMALE; HUMANS; MALE; MARIJUANA ABUSE; MENTAL DISORDERS; RISK FACTORS; SMOKING; STREET DRUGS; SUBSTANCE-RELATED DISORDERS; TOBACCO USE DISORDER; TWINS, DIZYGOTIC; TWINS, MONOZYGOTIC;

EID: 54049139959     PISSN: 09652140     EISSN: 13600443     Source Type: Journal    
DOI: 10.1111/j.1360-0443.2008.02354.x     Document Type: Article

References (70)

1. Kandel D. Stages and Pathways of Drug Involvement. New York, NY : Cambridge University Press 2002.
2. Hall W., Lynskey M. Is cannabis a gateway drug: testing hypotheses about the relationship between cannabis use and use of other illicit drugs. Drug Alcohol Rev 2005 24 : 39 48.
3. Lynskey M. T., Heath A. C., Bucholz K. K., Slutske W., Madden P. A., Nelson E. C. et al. Escalation of drug use in early-onset cannabis users vs co-twin controls. JAMA 2003 289 : 427 33.
4. Agrawal A., Neale M. C., Prescott C. A., Kendler K. S. A twin study of early cannabis use and subsequent use and abuse/dependence of other illicit drugs. Psychol Med 2004 34 : 1227 37.
5. Lessem J. M., Hopfer C. J., Haberstick B. C., Timberlake D., Ehringer M. A., Smolen A. et al. Relationship between adolescent marijuana use and young adult illicit drug use. Behav Genet 2006 36 : 498 506.
6. Lynskey M., Vink J. M., Boomsma D. I. Early onset cannabis use and progression to other drug use in a sample of Dutch twins. Behav Genet 2006 36 : 195 200.
7. Patton G. C., Coffey C., Carlin J. B., Sawyer S. M., Wakefield M. Teen smokers reach their mid twenties. J Adolesc Health 2006 39 : 214 20.
8. Patton G. C., Coffey C., Carlin J. B., Sawyer S. M., Lynskey M. Reverse gateways? Frequent cannabis use as a predictor of tobacco initiation and nicotine dependence. Addiction 2005 100 : 1518 25.
9. Timberlake D. S., Haberstick B. C., Hopfer C. J., Bricker J., Sakai J., Lessem J. et al. Progression from marijuana use to daily smoking and nicotine dependence in a national sample of U.S. adolescents. Drug Alcohol Depend 2007 88 : 272 81.
10. Agrawal A., Lynskey M. The genetic epidemiology of cannabis use, abuse and dependence: a review. Addiction 2006 101 : 801 12.
11. Madden P. A., Heath A. C., Pedersen N. L., Kaprio J., Koskenvuo M. J., Martin N. G. The genetics of smoking persistence in men and women: a multicultural study. Behav Genet 1999 29 : 423 31.
12. Sullivan P. F., Kendler K. S. The genetic epidemiology of smoking. Nicotine Tob Res 1999 1 (Suppl 2 S51 S57.
13. Carmelli D., Swan G. E., Robinette D., Fabsitz R. Genetic influence on smoking - a study of male twins. N Engl J Med 1992 327 : 829 33.
14. Heath A. C. Persist or quit? Testing for a genetic contribution to smoking persistence. Acta Genet Med Gemellol (Roma) 1990 39 : 447 58.
15. Lessov C. N., Martin N. G., Statham D. J., Todorov A., Slutske W., Bucholz K. K. et al. Defining nicotine dependence for genetic research: evidence from Australian twins. Psychol Med 2004 34 : 865 79.
16. Pergadia M. L., Heath A. C., Martin N. G., Madden P. A. Genetic analysis of DSM-IV nicotine withdrawal in adult twins. Psychol Med 2006 36 : 963 72.
17. Neale M. C., Harvey E., Maes H. H., Sullivan P. F., Kendler K. S. Extensions to the modeling of initiation and progression: applications to substance use and abuse. Behav Genet 2006 36 : 507 24.
18. Heath A. C., Howells W., Kirk K. M., Madden P. A., Bucholz K. K., Nelson E. C., et al. Predictors of non-response to a questionnaire survey of a volunteer twin panel: findings from the Australian 1989 twin cohort. Twin Res 2001 4 : 73 80.
19. Bucholz K. K., Cadoret R. J., Cloninger R. C., Dinwiddie S. H., Hesselbrock V., Nurnberger J. I. et al. A New, semi-structured psychiatric interview for use in genetic linkage studies. J Stud Alcohol 1994 55 : 149 58.
20. Cottler L. B., Robins L. N., Grant B. F., Blaine J., Towle S. H., Wittchen H. U. et al. The CIDI-core substance abuse and dependence questions: cross-cultural and nosological issues. The WHO/ADAMHA field trial. Br J Psychiatry 1991 159 : 653 8.
21. Centers for Disease Control and Prevention. Cigarette smoking among adults - United States, 1991. MMWR 1993 42 : 230 3.
22. Kendler K. S., Neale M. C., MacLean C. J., Heath A. C., Eaves L. J., Kessler R. C. Smoking and major depression. A causal analysis. Arch Gen Psychiatry 1993 50 : 36 43.
23. Johnson E. O., Breslau N. Is the association of smoking and depression a recent phenomenon? Nicotine Tob Res 2006 8 : 257 62.
24. Johnson E. O., Rhee S. H., Chase G. A., Breslau N. Comorbidity of depression with levels of smoking: an exploration of the shared familial risk hypothesis1. Nicotine Tob Res 2004 6 : 1029 38.
25. Degenhardt L., Hall W., Lynskey M. Exploring the association between cannabis use and depression. Addiction 2003 98 : 1493 504.
26. Fu Q., Heath A. C., Bucholz K. K., Nelson E., Goldberg J., Lyons M. J. et al. Shared genetic risk of major depression, alcohol dependence, and marijuana dependence: contribution of antisocial personality disorder in men. Arch Gen Psychiatry 2002 59 : 1125 32.
27. Lynskey M. T., Glowinski A. L., Todorov A. A., Bucholz K. K., Madden P. A. Nelson E. C. et al. Major depressive disorder, suicidal ideation, and suicide attempt in twins discordant for cannabis dependence and early-onset cannabis use. Arch Gen Psychiatry 2004 61 : 1026 32.
28. Donovan J. E., Jessor R. Structure of problem behavior in adolescence and young adulthood. J Consult Clin Psychol 1985 53 : 890 904.
29. Breslau N., Novak S. P., Kessler R. C. Psychiatric disorders and stages of smoking. Biol Psychiatry 2004 55 : 69 76.
30. Dembo R., Dertke M., La V. L., Borders S., Washburn M., Schmeidler J. Physical abuse, sexual victimization and illicit drug use: a structural analysis among high risk adolescents. J Adolesc 1987 10 : 13 34.
31. Harrison P. A., Fulkerson J. A., Beebe T. J. Multiple substance use among adolescent physical and sexual abuse victims. Child Abuse Negl 1997 21 : 529 39.
32. Neumann D. A., Houskamp B. M., Pollack V. E., Briere J. The long term sequelae of childhood sexual abuse in women. Child Maltreatment 1996 1 : 6 16.
33. Bushnell J. A., Wells J. E., Oakley-Browne M. A. Long-term effects of intrafamilial sexual abuse in childhood. Acta Psychiatr Scand 1992 85 : 136 42.
34. Dube S. R., Anda R. F., Whitfield C. L., Brown D. W., Felitti V. J., Dong M. et al. Long-term consequences of childhood sexual abuse by gender of victim. Am J Prev Med 2005 28 : 430 8.
35. Nelson E. C., Heath A. C., Madden P. A., Cooper M. L., Dinwiddie S. H., Bucholz K. K. et al. Association between self-reported childhood sexual abuse and adverse psychosocial outcomes: results from a twin study. Arch Gen Psychiatry 2002 59 : 139 45.
36. Collins L. M., Graham J. W., Long J., Hansen W. B. Crossvalidation of latent class models of early substance use onset. Multivariate Behav Res 1994 29 : 165 83.
37. Pergadia M. L., Heath A. C., Agrawal A., Bucholz K. K., Martin N. G., Madden P. A. The implications of simultaneous smoking initiation for inferences about the genetics of smoking behavior from twin data. Behav Genet 2006 36 : 567 76.
38. Neale M. C. Statistical modeling with Mx. Department of Psychiatry, Box # 980710, Richmond VA 23298, USA, 2004.
39. Amos A., Wiltshire S., Bostock Y., Haw S., McNeill A. 'You can't go without a fag. you need it for your hash' - a qualitative exploration of smoking, cannabis and young people. Addiction 2004 99 : 77 81.
40. Ream G. L., Benoit E., Johnson B. D., Dunlap E. Smoking tobacco along with marijuana increases symptoms of cannabis dependence. Drug Alcohol Depend 2008 95 : 199 208.
41. Agrawal A., Madden P., Bucholz K., Heath A., Lynskey M. Transitions to regular smoking and to nicotine dependence in women using cannabis. Drug Alcohol Depend 2008 95 : 107 14.
42. Han C., McGue M. K., Iacono W. G. Lifetime tobacco, alcohol and other substance use in adolescent Minnesota twins: univariate and multivariate behavioral genetic analyses. Addiction 1999 94 : 981 93.
43. Young S. E., Rhee S. H., Stallings M. C., Corley R. P., Hewitt J. K. Genetic and environmental vulnerabilities underlying adolescent substance use and problem use: general or specific?. Behav Genet 2006 36 : 603 15.
44. Krueger R. F., Hicks B. M., Patrick C. J., Carlson S. R., Iacono W. G., McGue M. Etiologic connections among substance dependence, antisocial behavior, and personality: modeling the externalizing spectrum. J Abnorm Psychol 2002 111 : 411 24.
45. Elkins I. J., King S. M., McGue M., Iacono W. G. Personality traits and the development of nicotine, alcohol, and illicit drug disorders: prospective links from adolescence to young adulthood. J Abnorm Psychol 2006 115 : 26 39.
46. Walden B., McGue M., Lacono W. G., Burt S. A., Elkins I. Identifying shared environmental contributions to early substance use: the respective roles of peers and parents. J Abnorm Psychol 2004 113 : 440 50.
47. Iacono W. G., Carlson S. R., Taylor J., Elkins I. J., McGue M. Behavioral disinhibition and the development of substance-use disorders: findings from the Minnesota twin family study. Dev Psychopathol 1999 11 : 869 900.
48. Kendler K. S., Prescott C. A., Myers J., Neale M. C. The structure of genetic and environmental risk factors for common psychiatric and substance use disorders in men and women. Arch Gen Psychiatry 2003 60 : 929 37.
49. Edenberg H. J., Dick D. M., Xuei X., Tian H., Almasy L., Bauer L. O. et al. Variations in GABRA2, encoding the alpha 2 subunit of the GABA(A) receptor, are associated with alcohol dependence and with brain oscillations. Am J Hum Genet 2004 74 : 705 14.
50. Fehr C., Sander T., Tadic A., Lenzen K. P., Anghelescu I., Klawe C. et al. Confirmation of association of the GABRA2 gene with alcohol dependence by subtype-specific analysis. Psychiatr Genet 2006 16 : 9 17.
51. Lappalainen J., Krupitsky E., Remizov M., Pchelina S., Taraskina A., Zvartau E. et al. Association between alcoholism and gamma-amino butyric acid alpha2 receptor subtype in a Russian population. Alcohol Clin Exp Res 2005 29 : 493 8.
52. Covault J., Gelernter J., Hesselbrock V., Nellissery M., Kranzler H. R. Allelic and haplotypic association of GABRA2 with alcohol dependence. Am J Med Genet B Neuropsychiatr Genet 2004 129 : 104 9.
53. Agrawal A., Edenberg H. J., Foroud T., Bierut L. J., Dunne G., Hinrichs A. L. et al. Association of GABRA2 with drug dependence in the collaborative study of the genetics of alcoholism sample. Behav Genet 2006 36 : 640 50.
54. Agrawal A., Pergadia M. L., Saccone S. F., Hinrichs A. L., Lessov-Schlaggar C. N., Saccone N. L. et al. Gamma-aminobutyric acid receptor genes and nicotine dependence: evidence for association from a case-control study. Addiction 2008 103 : 1027 38.
55. Dick D. M., Bierut L. J., Hinrichs A. L., Fox L., Bucholz K. K., Kramer J. et al. The role of GABRA2 in risk for conduct disorder and alcohol and drug dependence across different developmental stages. Behav Genet 2006 36 : 577 90.
56. Devane W. A., Hanus L., Breuer A., Pertwee R. G., Stevenson L. A., Griffin G. et al. Isolation and structure of a brain constituent that binds to the cannabinoid receptor. Science 1992 258 : 1946 9.
57. Yamamoto T., Takada K. Role of cannabinoid receptor in the brain as it relates to drug reward. Jpn J Pharmacol 2000 84 : 229 36.
58. Zimmer A., Zimmer A. M., Hohmann A. G., Herkenham M., Bonner T. I. Increased mortality, hypoactivity, and hypoalgesia in cannabinoid CB1 receptor knockout mice. Proc Natl Acad Sci USA 1999 96 : 5780 5.
59. Lichtman A. H., Martin B. R. Cannabinoid tolerance and dependence. Handb Exp Pharmacol 2005 168 : 691 717.
60. Zhang P.W., Ishiguro H., Ohtsuki T., Hess J., Carillo F., Walther D. et al. Human cannabinoid receptor 1 : 5′ exons, candidate regulatory regions, polymorphisms, haplotypes and association with polysubstance abuse. Mol Psychiatry 2004 9 : 916 31.
61. Hopfer C. J., Young S. E., Purcell S., Crowley T. J., Stallings M. C., Corley R. P. et al. Cannabis receptor haplotype associated with fewer cannabis dependence symptoms in adolescents. Am J Med Genet B Neuropsychiatr Genet 2006 141 : 895 901.
62. Zuo L., Kranzler H. R., Luo X., Covault J., Gelernter J. CNR1 variation modulates risk for drug and alcohol dependence. Biol Psychiatry 2007 62 : 616 26
63. Herman A. I., Kranzler H. R., Cubells J. F., Gelernter J., Covault J. Association study of the CNR1 gene exon 3 alternative promoter region polymorphisms and substance dependence. Am J Med Genet B Neuropsychiatr Genet 2006 141 : 499 503.
64. Siu E. C., Tyndale R. F. Non-nicotinic therapies for smoking cessation. Annu Rev Pharmacol Toxicol 2007 47 : 541 64.
65. Gelfand E. V., Cannon C. P. Rimonabant: a selective blocker of the cannabinoid CB1 receptors for the management of obesity, smoking cessation and cardiometabolic risk factors. Expert Opin Investig Drugs 2006 15 : 307 15.
66. Le F. B., Goldberg S. R. Rimonabant, a CB1 antagonist, blocks nicotine-conditioned place preferences. Neuroreport 2004 15 : 2139 43.
67. Castane A., Valjent E., Ledent C., Parmentier M., Maldonado R., Valverde O. Lack of CB1 cannabinoid receptors modifies nicotine behavioural responses, but not nicotine abstinence. Neuropharmacology 2002 43 : 857 67.
68. Garwood C. L., Potts L. A. Emerging pharmacotherapies for smoking cessation. Am J Health Syst Pharm 2007 64 : 1693 8.
69. Cahill K., Ussher M. Cannabinoid type 1 receptor antagonists (rimonabant) for smoking cessation. Cochrane Database Syst Rev 2007, Issue 4; CD005353. DOI: 10.1002/14651858.CD005353.pub3
70. Muccioli G. G. Blocking the cannabinoid receptors: drug candidates and therapeutic promises. Chem Biodivers 2007 4 : 1805 27.