Stochastic simulations of ErbB homo and heterodimerisation: Potential impacts of receptor conformational state and spatial segregation

IET Systems Biology

Volumn 2, Issue 5, 2008, Pages 256-272

  Hsieh, M Y ^a   Yang, S ^b   Raymond Stinz, M A ^b   Steinberg, S ^c   Vlachos, D G ^e   Shu, W ^a   Wilson, B ^b   Edwards, J S ^d  

^a University of New Mexico   (United States)

^b UNIVERSITY OF NEW MEXICO HEALTH SCIENCES CENTER   (United States)

^c UNIVERSITY OF NEW MEXICO   (United States)

^d University of Delaware   (United States)

^e UNIVERSITY OF NEW MEXICO SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

FLOW OF SOLIDS; LIGANDS; OLIGOMERIZATION; OLIGOMERS; PATHOLOGY; PROBABILITY; SEGREGATION (METALLOGRAPHY); STOCHASTIC CONTROL SYSTEMS; STOCHASTIC PROGRAMMING;

BREAST CANCER CELLS; CLUSTERING; COMPETENT CONFORMATIONS; CONFORMATIONAL STATES; DENSITY DEPENDENTS; EPIDERMAL GROWTH FACTOR RECEPTORS; HOMODIMERS; IMMUNOELECTRON MICROSCOPIES; LIGHT RECEPTORS; OLIGOMERISATION; OPEN CONFORMATIONS; OVEREXPRESSION; POTENTIAL IMPACTS; RARE EVENTS; RECEPTOR LEVELS; SPATIAL SEGREGATIONS; SPATIAL STOCHASTIC; STOCHASTIC SIMULATIONS; UNIFORMLY DISTRIBUTED;

BIOACTIVITY;

EPIDERMAL GROWTH FACTOR RECEPTOR; EPIDERMAL GROWTH FACTOR RECEPTOR 2; EPIDERMAL GROWTH FACTOR RECEPTOR 3;

AUTOCRINE EFFECT; CARCINOGENESIS; CONFERENCE PAPER; CONTROLLED STUDY; DIMERIZATION; ENZYME ACTIVATION; ENZYME PHOSPHORYLATION; GENE CLUSTER; GENE OVEREXPRESSION; HUMAN; HUMAN CELL; IMMUNOELECTRON MICROSCOPY; LIGAND BINDING; OLIGOMERIZATION; PROTEIN CONFORMATION; RECEPTOR DENSITY; SIGNAL TRANSDUCTION; STOCHASTIC MODEL; SYSTEMS BIOLOGY;

CELL MEMBRANE; COMPUTER SIMULATION; DIMERIZATION; MODELS, BIOLOGICAL; MODELS, CHEMICAL; MODELS, MOLECULAR; PROTEIN CONFORMATION; RECEPTOR, ERBB-2; STOCHASTIC PROCESSES; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 54049134792     PISSN: 17518849     EISSN: None     Source Type: Journal    
DOI: 10.1049/iet-syb:20070073     Document Type: Conference Paper

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