Association between the HLA-A2 allele and Alzheimer disease

Rejuvenation Research

Volumn 9, Issue 1, 2006, Pages 99-101

  Listì, Florinda ^a   Candore, Giuseppina ^a   Balistreri, Carmela Rita ^a   Grimaldi, Maria Paola ^a   Orlando, Valentina ^a   Vasto, Sonya ^a   Colonna Romano, Giuseppina ^a   Lio, Domenico ^a   Licastro, Federico ^b   Franceschi, Claudio ^b,c   Caruso, Calogero ^d  

^a UNIVERSITY OF PALERMO   (Italy)

^b UNIVERSITY OF BOLOGNA   (Italy)

^c INRCA   (Italy)

^d NONE

Author keywords

[No Author keywords available]

Indexed keywords

HLA A2 ANTIGEN;

ADULT; AGED; ALLELE; ALZHEIMER DISEASE; CONFERENCE PAPER; CONTROLLED STUDY; DEGENERATIVE DISEASE; DEMENTIA; DISEASE PREDISPOSITION; ENVIRONMENTAL FACTOR; GENE FREQUENCY; GENETIC ASSOCIATION; GENETIC HETEROGENEITY; GENETIC POLYMORPHISM; HEREDITY; HUMAN; INFLAMMATION; ITALY; MAJOR CLINICAL STUDY; MAJOR HISTOCOMPATIBILITY COMPLEX; MOLECULAR TYPING; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; SINGLE STRAND CONFORMATION POLYMORPHISM;

AGED; AGED, 80 AND OVER; ALZHEIMER DISEASE; FEMALE; GENE FREQUENCY; GENETIC PREDISPOSITION TO DISEASE; GENOTYPE; HLA-A2 ANTIGEN; HUMANS; MALE; MIDDLE AGED;

EID: 33646073705     PISSN: 15491684     EISSN: None     Source Type: Journal    
DOI: 10.1089/rej.2006.9.99     Document Type: Conference Paper

References (14)

1. Licastro F, Candore G, Lio D, et al. Innate immunity and inflammation in ageing: a key for understanding age-related disease. Immun Ageing 2005;2:8. Available at: http://www.immunityageing.com/content/2/1/8.
2. Candore G, Balistreri CR, Colonna-Romano G, et al. Major histocompatibility complex and sporadic Alzheimer's disease: a critical reappraisal. Exp Gerontol 2004;39:645-652.
3. Lio D, Licastro F, Scola L, et al. Interleukin-10 promoter polymorphism in sporadic Alzheimer's disease. Genes Immunol 2003;4:234-238.
4. Licastro F, Grimaldi LM, Bonafe M, et al. Interleukin-6 gene alleles affect the risk of Alzheimer's disease and levels of the cytokine in blood and brain. Neurobiol Aging 2003;24:921-926.
5. Payarni H, Kaye J, Becker W, et al. HLA-A2, or a closely linked gene, confers susceptibility to early-on-set sporadic Alzheimer's disease in men. Neurology 1991;41:1544-1548.
6. Araria-Goumidi L, Lambert JC, Cottel D, et al. No association of the HLA-A2 allele with Alzheimer's disease. Neurosci Lett 2002;335:75-78.
7. Combarros O, Escribano J, Sanchez-Velasco P, et al. Association of HLA-A2 allele is associated with age at onset of Alzheimer's disease. Acta Neurol Scand 1998;98:140-141.
8. Ballerini C, Nacmias B, Rombolà G, et al. HLA-A2 allele is associated with age at onset of Alzheimer's disease. Ann Neurol 1999;45:397-400.
9. Small GW, Scott WK, Komo S, et al. No association between the HLA-A2 allele and Alzheimer disease. Neurogenetics 1999;2:177-182.
10. Harris JM, Cumming AM, Craddock N, et al. Human leucocyte antigen-A2 increases risk of Alzheimer's disease but does not affect age of onset in a Scottish population. Neurosci Lett 2000;294:37-40.
11. Caruso C, Candore G, Colonna-Romano G, et al. Immunogenetics of Longevity. Is major histocompatibility complex polymorphism relevant to the control of human longevity? A review of literature data. Mech Ageing Dev 2001;122:445-462.
12. Dobson CB, Wozniak MA, Itzhaki RF. Do infectious agents play a role in dementia? Trends Microbiol 2003;11:312-317.
13. Candore G, Lio D, Colonna Romano G, et al. Pathogenesis of autoimmune diseases associated with 8.1 ancestral haplotype: effect of multiple gene interactions. Autoimmun Rev 2002;1:29-35.
14. Williams F, Middleton D, Savage D, et al. Development of PCR-SSOP for the identification of HLA-A*02 subtypes and determination of HLA-A*02 frequencies within different ethnic populations. Tissue Antigens 1997;49:129-133.