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Volumn 18, Issue 3, 2008, Pages 261-269

Signaling by synaptogenic molecules

Author keywords

[No Author keywords available]

Indexed keywords

CELL ADHESION MOLECULE; IMMUNOGLOBULIN G; INTEGRIN; MEMBRANE RECEPTOR; NEUREXIN; NEUROLIGIN;

EID: 53949121597     PISSN: 09594388     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.conb.2008.07.014     Document Type: Review
Times cited : (57)

References (71)
  • 1
    • 0024489542 scopus 로고
    • Fine structure of synaptogenesis in the vertebrate central nervous system
    • Vaughn J.E. Fine structure of synaptogenesis in the vertebrate central nervous system. Synapse 3 (1989) 255-285
    • (1989) Synapse , vol.3 , pp. 255-285
    • Vaughn, J.E.1
  • 2
    • 34547701950 scopus 로고    scopus 로고
    • Dynamic aspects of CNS synapse formation
    • McAllister A.K. Dynamic aspects of CNS synapse formation. Annu Rev Neurosci 30 (2007) 425-450
    • (2007) Annu Rev Neurosci , vol.30 , pp. 425-450
    • McAllister, A.K.1
  • 3
    • 33744535466 scopus 로고    scopus 로고
    • Cell adhesion molecules at the synapse
    • Gerrow K., and El-Husseini A. Cell adhesion molecules at the synapse. Front Biosci 11 (2006) 2400-2419
    • (2006) Front Biosci , vol.11 , pp. 2400-2419
    • Gerrow, K.1    El-Husseini, A.2
  • 4
    • 33847119026 scopus 로고    scopus 로고
    • Cell adhesion molecules: signalling functions at the synapse
    • Dalva M.B., McClelland A.C., and Kayser M.S. Cell adhesion molecules: signalling functions at the synapse. Nat Rev Neurosci 8 (2007) 206-220
    • (2007) Nat Rev Neurosci , vol.8 , pp. 206-220
    • Dalva, M.B.1    McClelland, A.C.2    Kayser, M.S.3
  • 5
    • 33846867244 scopus 로고    scopus 로고
    • Neurexin-neuroligin signaling in synapse development
    • Craig A.M., and Kang Y. Neurexin-neuroligin signaling in synapse development. Curr Opin Neurobiol 17 (2007) 43-52
    • (2007) Curr Opin Neurobiol , vol.17 , pp. 43-52
    • Craig, A.M.1    Kang, Y.2
  • 6
    • 46549088971 scopus 로고    scopus 로고
    • GABA and neuroligin signaling: linking synaptic activity and adhesion in inhibitory synapse development
    • Huang Z.J., and Scheiffele P. GABA and neuroligin signaling: linking synaptic activity and adhesion in inhibitory synapse development. Curr Opin Neurobiol 18 (2008) 77-83
    • (2008) Curr Opin Neurobiol , vol.18 , pp. 77-83
    • Huang, Z.J.1    Scheiffele, P.2
  • 7
    • 32344434917 scopus 로고    scopus 로고
    • A preformed complex of postsynaptic proteins is involved in excitatory synapse development
    • Gerrow K., Romorini S., Nabi S.M., Colicos M.A., Sala C., and El-Husseini A. A preformed complex of postsynaptic proteins is involved in excitatory synapse development. Neuron 49 (2006) 547-562
    • (2006) Neuron , vol.49 , pp. 547-562
    • Gerrow, K.1    Romorini, S.2    Nabi, S.M.3    Colicos, M.A.4    Sala, C.5    El-Husseini, A.6
  • 8
    • 33750951076 scopus 로고    scopus 로고
    • Formation of presynaptic terminals at predefined sites along axons
    • Sabo S.L., Gomes R.A., and McAllister A.K. Formation of presynaptic terminals at predefined sites along axons. J Neurosci 26 (2006) 10813-10825
    • (2006) J Neurosci , vol.26 , pp. 10813-10825
    • Sabo, S.L.1    Gomes, R.A.2    McAllister, A.K.3
  • 9
    • 13544269142 scopus 로고    scopus 로고
    • Control of excitatory and inhibitory synapse formation by neuroligins
    • Chih B., Engelman H., and Scheiffele P. Control of excitatory and inhibitory synapse formation by neuroligins. Science 307 (2005) 1324-1328
    • (2005) Science , vol.307 , pp. 1324-1328
    • Chih, B.1    Engelman, H.2    Scheiffele, P.3
  • 10
    • 33745994650 scopus 로고    scopus 로고
    • Alternative splicing controls selective trans-synaptic interactions of the neuroligin-neurexin complex
    • Chih B., Gollan L., and Scheiffele P. Alternative splicing controls selective trans-synaptic interactions of the neuroligin-neurexin complex. Neuron 51 (2006) 171-178
    • (2006) Neuron , vol.51 , pp. 171-178
    • Chih, B.1    Gollan, L.2    Scheiffele, P.3
  • 11
    • 33646464124 scopus 로고    scopus 로고
    • Structure function and splice site analysis of the synaptogenic activity of the neurexin-1 beta LNS domain
    • Graf E.R., Kang Y., Hauner A.M., and Craig A.M. Structure function and splice site analysis of the synaptogenic activity of the neurexin-1 beta LNS domain. J Neurosci 26 (2006) 4256-4265
    • (2006) J Neurosci , vol.26 , pp. 4256-4265
    • Graf, E.R.1    Kang, Y.2    Hauner, A.M.3    Craig, A.M.4
  • 12
    • 34250211762 scopus 로고    scopus 로고
    • Activity-dependent validation of excitatory versus inhibitory synapses by neuroligin-1 versus neuroligin-2
    • Chubykin A.A., Atasoy D., Etherton M.R., Brose N., Kavalali E.T., Gibson J.R., and Südhof T.C. Activity-dependent validation of excitatory versus inhibitory synapses by neuroligin-1 versus neuroligin-2. Neuron 54 (2007) 919-931
    • (2007) Neuron , vol.54 , pp. 919-931
    • Chubykin, A.A.1    Atasoy, D.2    Etherton, M.R.3    Brose, N.4    Kavalali, E.T.5    Gibson, J.R.6    Südhof, T.C.7
  • 13
    • 38349098974 scopus 로고    scopus 로고
    • Induction of GABAergic postsynaptic differentiation by alpha-neurexins
    • Kang Y., Zhang X., Dobie F., Wu H., and Craig A.M. Induction of GABAergic postsynaptic differentiation by alpha-neurexins. J Biol Chem 283 (2008) 2323-2334
    • (2008) J Biol Chem , vol.283 , pp. 2323-2334
    • Kang, Y.1    Zhang, X.2    Dobie, F.3    Wu, H.4    Craig, A.M.5
  • 14
    • 33846564563 scopus 로고    scopus 로고
    • Retrograde modulation of presynaptic release probability through signaling mediated by PSD-95-neuroligin
    • The authors demonstrate that postsynaptic neuroligin 1 and its partner PSD-95 cooperate to control glutamate release probability, providing evidence for a new trans-synaptic mechanism regulating presynaptic physiology.
    • Futai K., Kim M.J., Hashikawa T., Scheiffele P., Sheng M., and Hayashi Y. Retrograde modulation of presynaptic release probability through signaling mediated by PSD-95-neuroligin. Nat Neurosci 10 (2007) 186-195. The authors demonstrate that postsynaptic neuroligin 1 and its partner PSD-95 cooperate to control glutamate release probability, providing evidence for a new trans-synaptic mechanism regulating presynaptic physiology.
    • (2007) Nat Neurosci , vol.10 , pp. 186-195
    • Futai, K.1    Kim, M.J.2    Hashikawa, T.3    Scheiffele, P.4    Sheng, M.5    Hayashi, Y.6
  • 15
    • 26944444692 scopus 로고    scopus 로고
    • A splice code for trans-synaptic cell adhesion mediated by binding of neuroligin 1 to alpha- and beta-neurexins
    • Boucard A.A., Chubykin A.A., Comoletti D., Taylor P., and Südhof T.C. A splice code for trans-synaptic cell adhesion mediated by binding of neuroligin 1 to alpha- and beta-neurexins. Neuron 48 (2005) 229-236
    • (2005) Neuron , vol.48 , pp. 229-236
    • Boucard, A.A.1    Chubykin, A.A.2    Comoletti, D.3    Taylor, P.4    Südhof, T.C.5
  • 17
    • 33748531328 scopus 로고    scopus 로고
    • Neuroligins determine synapse maturation and function
    • This study of neuroligins in knock-out mice demonstrates vital functions in balancing excitatory and inhibitory transmission. Unexpectedly, no evidence for roles in synapse formation was obtained.
    • Varoqueaux F., Aramuni G., Rawson R.L., Mohrmann R., Missler M., Gottmann K., Zhang W., Südhof T.C., and Brose N. Neuroligins determine synapse maturation and function. Neuron 51 (2006) 741-754. This study of neuroligins in knock-out mice demonstrates vital functions in balancing excitatory and inhibitory transmission. Unexpectedly, no evidence for roles in synapse formation was obtained.
    • (2006) Neuron , vol.51 , pp. 741-754
    • Varoqueaux, F.1    Aramuni, G.2    Rawson, R.L.3    Mohrmann, R.4    Missler, M.5    Gottmann, K.6    Zhang, W.7    Südhof, T.C.8    Brose, N.9
  • 18
    • 34548316270 scopus 로고    scopus 로고
    • Crucial role of Drosophila neurexin in proper active zone apposition to postsynaptic densities, synaptic growth, and synaptic transmission
    • Li J., Ashley J., Budnik V., and Bhat M.A. Crucial role of Drosophila neurexin in proper active zone apposition to postsynaptic densities, synaptic growth, and synaptic transmission. Neuron 55 (2007) 741-755
    • (2007) Neuron , vol.55 , pp. 741-755
    • Li, J.1    Ashley, J.2    Budnik, V.3    Bhat, M.A.4
  • 19
    • 34249059390 scopus 로고    scopus 로고
    • Neurexin-1 is required for synapse formation and larvae associative learning in Drosophila
    • Zeng X., Sun M., Liu L., Chen F., Wei L., and Xie W. Neurexin-1 is required for synapse formation and larvae associative learning in Drosophila. FEBS Lett 581 (2007) 2509-2516
    • (2007) FEBS Lett , vol.581 , pp. 2509-2516
    • Zeng, X.1    Sun, M.2    Liu, L.3    Chen, F.4    Wei, L.5    Xie, W.6
  • 21
    • 35148858044 scopus 로고    scopus 로고
    • A neuroligin-3 mutation implicated in autism increases inhibitory synaptic transmission in mice
    • The authors analyze a mouse model carrying a neuroligin 3 mutation identified in human autism-spectrum disorders and observe a probable toxic gain-of-function effect on behavior. These findings link aberrant circuitry formation to autism.
    • Tabuchi K., Blundell J., Etherton M.R., Hammer R.E., Liu X., Powell C.M., and Sudhof T.C. A neuroligin-3 mutation implicated in autism increases inhibitory synaptic transmission in mice. Science 318 (2007) 71-76. The authors analyze a mouse model carrying a neuroligin 3 mutation identified in human autism-spectrum disorders and observe a probable toxic gain-of-function effect on behavior. These findings link aberrant circuitry formation to autism.
    • (2007) Science , vol.318 , pp. 71-76
    • Tabuchi, K.1    Blundell, J.2    Etherton, M.R.3    Hammer, R.E.4    Liu, X.5    Powell, C.M.6    Sudhof, T.C.7
  • 27
    • 36248987849 scopus 로고    scopus 로고
    • SynCAMs organize synapses through heterophilic adhesion
    • This study identifies a heterophilic trans-synaptic adhesion complex constituted by the synaptic SynCAM Ig proteins 1 and 2 that organizes nascent synapses to promote transmission, indicative of an adhesive code.
    • Fogel A.I., Akins M.R., Krupp A.J., Stagi M., Stein V., and Biederer T. SynCAMs organize synapses through heterophilic adhesion. J Neurosci 27 (2007) 12516-12530. This study identifies a heterophilic trans-synaptic adhesion complex constituted by the synaptic SynCAM Ig proteins 1 and 2 that organizes nascent synapses to promote transmission, indicative of an adhesive code.
    • (2007) J Neurosci , vol.27 , pp. 12516-12530
    • Fogel, A.I.1    Akins, M.R.2    Krupp, A.J.3    Stagi, M.4    Stein, V.5    Biederer, T.6
  • 28
    • 50249129263 scopus 로고    scopus 로고
    • Expression and adhesion profiles of SynCAM molecules indicate distinct neuronal functions
    • Thomas L.A., Akins M.R., and Biederer T. Expression and adhesion profiles of SynCAM molecules indicate distinct neuronal functions. J Comp Neurol 510 (2008) 47-67
    • (2008) J Comp Neurol , vol.510 , pp. 47-67
    • Thomas, L.A.1    Akins, M.R.2    Biederer, T.3
  • 29
    • 33749026932 scopus 로고    scopus 로고
    • NGL family PSD-95-interacting adhesion molecules regulate excitatory synapse formation
    • The authors introduce a trans-synaptic signaling pathway organized by the postsynaptic membrane protein NGL2 that differentiates glutamatergic synapses.
    • Kim S., Burette A., Chung H.S., Kwon S.K., Woo J., Lee H.W., Kim K., Kim H., Weinberg R.J., and Kim E. NGL family PSD-95-interacting adhesion molecules regulate excitatory synapse formation. Nat Neurosci 9 (2006) 1294-1301. The authors introduce a trans-synaptic signaling pathway organized by the postsynaptic membrane protein NGL2 that differentiates glutamatergic synapses.
    • (2006) Nat Neurosci , vol.9 , pp. 1294-1301
    • Kim, S.1    Burette, A.2    Chung, H.S.3    Kwon, S.K.4    Woo, J.5    Lee, H.W.6    Kim, K.7    Kim, H.8    Weinberg, R.J.9    Kim, E.10
  • 30
    • 33646474616 scopus 로고    scopus 로고
    • SALM synaptic cell adhesion-like molecules regulate the differentiation of excitatory synapses
    • Ko J., Kim S., Chung H.S., Kim K., Han K., Kim H., Jun H., Kaang B.K., and Kim E. SALM synaptic cell adhesion-like molecules regulate the differentiation of excitatory synapses. Neuron 50 (2006) 233-245
    • (2006) Neuron , vol.50 , pp. 233-245
    • Ko, J.1    Kim, S.2    Chung, H.S.3    Kim, K.4    Han, K.5    Kim, H.6    Jun, H.7    Kaang, B.K.8    Kim, E.9
  • 31
    • 33645633317 scopus 로고    scopus 로고
    • A novel family of adhesion-like molecules that interacts with the NMDA receptor
    • Wang C.Y., Chang K., Petralia R.S., Wang Y.X., Seabold G.K., and Wenthold R.J. A novel family of adhesion-like molecules that interacts with the NMDA receptor. J Neurosci 26 (2006) 2174-2183
    • (2006) J Neurosci , vol.26 , pp. 2174-2183
    • Wang, C.Y.1    Chang, K.2    Petralia, R.S.3    Wang, Y.X.4    Seabold, G.K.5    Wenthold, R.J.6
  • 33
    • 43249095051 scopus 로고    scopus 로고
    • Bergmann glia and the recognition molecule CHL1 organize GABAergic axons and direct innervation of Purkinje cell dendrites
    • Ango F., Wu C., Van der Want J.J., Wu P., Schachner M., and Huang Z.J. Bergmann glia and the recognition molecule CHL1 organize GABAergic axons and direct innervation of Purkinje cell dendrites. PLoS Biol 6 (2008) e103
    • (2008) PLoS Biol , vol.6
    • Ango, F.1    Wu, C.2    Van der Want, J.J.3    Wu, P.4    Schachner, M.5    Huang, Z.J.6
  • 34
    • 36549085044 scopus 로고    scopus 로고
    • Cdk5 promotes synaptogenesis by regulating the subcellular distribution of the MAGUK family member CASK
    • This study establishes that presynaptic signaling through the kinase Cdk5 participates in synapse formation and regulates synaptic scaffolds.
    • Samuels B.A., Hsueh Y.-P., Shu T., Liang H., Tseng H.-C., Hong C.-J., Su S.C., Volker J., Neve R.L., Yue D.T., et al. Cdk5 promotes synaptogenesis by regulating the subcellular distribution of the MAGUK family member CASK. Neuron 56 (2007) 823-837. This study establishes that presynaptic signaling through the kinase Cdk5 participates in synapse formation and regulates synaptic scaffolds.
    • (2007) Neuron , vol.56 , pp. 823-837
    • Samuels, B.A.1    Hsueh, Y.-P.2    Shu, T.3    Liang, H.4    Tseng, H.-C.5    Hong, C.-J.6    Su, S.C.7    Volker, J.8    Neve, R.L.9    Yue, D.T.10
  • 35
    • 33845259344 scopus 로고    scopus 로고
    • SYD-2 liprin-alpha organizes presynaptic active zone formation through ELKS
    • Dai Y., Taru H., Deken S.L., Grill B., Ackley B., Nonet M.L., and Jin Y. SYD-2 liprin-alpha organizes presynaptic active zone formation through ELKS. Nat Neurosci 9 (2006) 1479-1487
    • (2006) Nat Neurosci , vol.9 , pp. 1479-1487
    • Dai, Y.1    Taru, H.2    Deken, S.L.3    Grill, B.4    Ackley, B.5    Nonet, M.L.6    Jin, Y.7
  • 36
    • 33845727992 scopus 로고    scopus 로고
    • The cadherin superfamily in neuronal connections and interactions
    • Takeichi M. The cadherin superfamily in neuronal connections and interactions. Nat Rev Neurosci 8 (2007) 11-20
    • (2007) Nat Rev Neurosci , vol.8 , pp. 11-20
    • Takeichi, M.1
  • 38
    • 33144455179 scopus 로고    scopus 로고
    • Structural basis for developmentally regulated changes in cadherin function at synapses
    • Elste A.M., and Benson D.L. Structural basis for developmentally regulated changes in cadherin function at synapses. J Comp Neurol 495 (2006) 324-335
    • (2006) J Comp Neurol , vol.495 , pp. 324-335
    • Elste, A.M.1    Benson, D.L.2
  • 39
    • 33746048845 scopus 로고    scopus 로고
    • BDNF mobilizes synaptic vesicles and enhances synapse formation by disrupting cadherin-beta-catenin interactions
    • Bamji S.X., Rico B., Kimes N., and Reichardt L.F. BDNF mobilizes synaptic vesicles and enhances synapse formation by disrupting cadherin-beta-catenin interactions. J Cell Biol 174 (2006) 289-299
    • (2006) J Cell Biol , vol.174 , pp. 289-299
    • Bamji, S.X.1    Rico, B.2    Kimes, N.3    Reichardt, L.F.4
  • 40
    • 33745501378 scopus 로고    scopus 로고
    • p120 catenin regulates dendritic spine and synapse development through Rho-family GTPases and cadherins
    • This work examines postsynaptic signaling by studying the cadherin/p120-catenin pathway. p120 regulates both cadherin amounts and small GTPase signaling to maintain proper spine maturation and synapse numbers in vivo.
    • Elia L.P., Yamamoto M., Zang K., and Reichardt L.F. p120 catenin regulates dendritic spine and synapse development through Rho-family GTPases and cadherins. Neuron 51 (2006) 43-56. This work examines postsynaptic signaling by studying the cadherin/p120-catenin pathway. p120 regulates both cadherin amounts and small GTPase signaling to maintain proper spine maturation and synapse numbers in vivo.
    • (2006) Neuron , vol.51 , pp. 43-56
    • Elia, L.P.1    Yamamoto, M.2    Zang, K.3    Reichardt, L.F.4
  • 41
    • 34147119506 scopus 로고    scopus 로고
    • alpha5 integrin signaling regulates the formation of spines and synapses in hippocampal neurons
    • Webb D.J., Zhang H., Majumdar D., and Horwitz A.F. alpha5 integrin signaling regulates the formation of spines and synapses in hippocampal neurons. J Biol Chem 282 (2007) 6929-6935
    • (2007) J Biol Chem , vol.282 , pp. 6929-6935
    • Webb, D.J.1    Zhang, H.2    Majumdar, D.3    Horwitz, A.F.4
  • 42
  • 43
    • 0347993700 scopus 로고    scopus 로고
    • Multiple EphB receptor tyrosine kinases shape dendritic spines in the hippocampus
    • Henkemeyer M., Itkis O.S., Ngo M., Hickmott P.W., and Ethell I.M. Multiple EphB receptor tyrosine kinases shape dendritic spines in the hippocampus. J Cell Biol 163 (2003) 1313-1326
    • (2003) J Cell Biol , vol.163 , pp. 1313-1326
    • Henkemeyer, M.1    Itkis, O.S.2    Ngo, M.3    Hickmott, P.W.4    Ethell, I.M.5
  • 44
    • 33751343894 scopus 로고    scopus 로고
    • Intracellular and trans-synaptic regulation of glutamatergic synaptogenesis by EphB receptors
    • This work demonstrates that the postsynaptic EphB2 receptor organizes glutamate receptor assembly and induces presynaptic terminals through interactions with its ephrinB ligand.
    • Kayser M.S., McClelland A.C., Hughes E.G., and Dalva M.B. Intracellular and trans-synaptic regulation of glutamatergic synaptogenesis by EphB receptors. J Neurosci 26 (2006) 12152-12164. This work demonstrates that the postsynaptic EphB2 receptor organizes glutamate receptor assembly and induces presynaptic terminals through interactions with its ephrinB ligand.
    • (2006) J Neurosci , vol.26 , pp. 12152-12164
    • Kayser, M.S.1    McClelland, A.C.2    Hughes, E.G.3    Dalva, M.B.4
  • 45
    • 38649088941 scopus 로고    scopus 로고
    • Ephrin-B reverse signaling promotes structural and functional synaptic maturation in vivo
    • The authors show that ephrinB reverse signaling into axons promotes bouton numbers and synaptic plasticity, demonstrating that presynaptic ephrinB organizes both synaptic differentiation and function.
    • Lim B.K., Matsuda N., and Poo M.-m. Ephrin-B reverse signaling promotes structural and functional synaptic maturation in vivo. Nat Neurosci 11 (2008) 160-169. The authors show that ephrinB reverse signaling into axons promotes bouton numbers and synaptic plasticity, demonstrating that presynaptic ephrinB organizes both synaptic differentiation and function.
    • (2008) Nat Neurosci , vol.11 , pp. 160-169
    • Lim, B.K.1    Matsuda, N.2    Poo, M.-m.3
  • 46
    • 34249856693 scopus 로고    scopus 로고
    • The Rac1 guanine nucleotide exchange factor Tiam1 mediates EphB receptor-dependent dendritic spine development
    • Tolias K.F., Bikoff J.B., Kane C.G., Tolias C.S., Hu L., and Greenberg M.E. The Rac1 guanine nucleotide exchange factor Tiam1 mediates EphB receptor-dependent dendritic spine development. Proc Natl Acad Sci U S A 104 (2007) 7265-7270
    • (2007) Proc Natl Acad Sci U S A , vol.104 , pp. 7265-7270
    • Tolias, K.F.1    Bikoff, J.B.2    Kane, C.G.3    Tolias, C.S.4    Hu, L.5    Greenberg, M.E.6
  • 47
    • 33644984716 scopus 로고    scopus 로고
    • EphB receptors regulate dendritic spine morphogenesis through the recruitment/phosphorylation of focal adhesion kinase and RhoA activation
    • Moeller M.L., Shi Y., Reichardt L.F., and Ethell I.M. EphB receptors regulate dendritic spine morphogenesis through the recruitment/phosphorylation of focal adhesion kinase and RhoA activation. J Biol Chem 281 (2006) 1587-1598
    • (2006) J Biol Chem , vol.281 , pp. 1587-1598
    • Moeller, M.L.1    Shi, Y.2    Reichardt, L.F.3    Ethell, I.M.4
  • 48
    • 33847196732 scopus 로고    scopus 로고
    • Grb4 and GIT1 transduce ephrinB reverse signals modulating spine morphogenesis and synapse formation
    • Segura I., Essmann C.L., Weinges S., and Acker-Palmer A. Grb4 and GIT1 transduce ephrinB reverse signals modulating spine morphogenesis and synapse formation. Nat Neurosci 10 (2007) 301-310
    • (2007) Nat Neurosci , vol.10 , pp. 301-310
    • Segura, I.1    Essmann, C.L.2    Weinges, S.3    Acker-Palmer, A.4
  • 49
    • 34447514177 scopus 로고    scopus 로고
    • Postsynaptic ephrinB3 promotes shaft glutamatergic synapse formation
    • Aoto J., Ting P., Maghsoodi B., Xu N., Henkemeyer M., and Chen L. Postsynaptic ephrinB3 promotes shaft glutamatergic synapse formation. J Neurosci 27 (2007) 7508-7519
    • (2007) J Neurosci , vol.27 , pp. 7508-7519
    • Aoto, J.1    Ting, P.2    Maghsoodi, B.3    Xu, N.4    Henkemeyer, M.5    Chen, L.6
  • 50
  • 51
    • 33749010358 scopus 로고    scopus 로고
    • Neurotrophin-regulated signalling pathways
    • Reichardt L.F. Neurotrophin-regulated signalling pathways. Philos Trans R Soc Lond B Biol Sci 361 (2006) 1545-1564
    • (2006) Philos Trans R Soc Lond B Biol Sci , vol.361 , pp. 1545-1564
    • Reichardt, L.F.1
  • 52
    • 44649198605 scopus 로고    scopus 로고
    • Insulin receptor signaling regulates synapse number, dendritic plasticity, and circuit function in vivo
    • Synaptic signaling receives an intriguing additional player with this study, identifying roles of the insulin receptor in maintaining synapse density and neuronal network function.
    • Chiu S.L., Chen C.M., and Cline H.T. Insulin receptor signaling regulates synapse number, dendritic plasticity, and circuit function in vivo. Neuron 58 (2008) 708-719. Synaptic signaling receives an intriguing additional player with this study, identifying roles of the insulin receptor in maintaining synapse density and neuronal network function.
    • (2008) Neuron , vol.58 , pp. 708-719
    • Chiu, S.L.1    Chen, C.M.2    Cline, H.T.3
  • 53
    • 34248531426 scopus 로고    scopus 로고
    • The neuregulin-1 receptor ErbB4 controls glutamatergic synapse maturation and plasticity
    • Li B., Woo R.-S., Mei L., and Malinow R. The neuregulin-1 receptor ErbB4 controls glutamatergic synapse maturation and plasticity. Neuron 54 (2007) 583-597
    • (2007) Neuron , vol.54 , pp. 583-597
    • Li, B.1    Woo, R.-S.2    Mei, L.3    Malinow, R.4
  • 55
    • 46049112457 scopus 로고    scopus 로고
    • Critical role of TRPC6 channels in the formation of excitatory synapses
    • Zhou J., Du W., Zhou K., Tai Y., Yao H., Jia Y., Ding Y., and Wang Y. Critical role of TRPC6 channels in the formation of excitatory synapses. Nat Neurosci 11 (2008) 741-743
    • (2008) Nat Neurosci , vol.11 , pp. 741-743
    • Zhou, J.1    Du, W.2    Zhou, K.3    Tai, Y.4    Yao, H.5    Jia, Y.6    Ding, Y.7    Wang, Y.8
  • 57
    • 34548511576 scopus 로고    scopus 로고
    • Wnt4 Is a local repulsive cue that determines synaptic target specificity
    • Inaki M., Yoshikawa S., Thomas J.B., Aburatani H., and Nose A. Wnt4 Is a local repulsive cue that determines synaptic target specificity. Curr Biol 17 (2007) 1574-1579
    • (2007) Curr Biol , vol.17 , pp. 1574-1579
    • Inaki, M.1    Yoshikawa, S.2    Thomas, J.B.3    Aburatani, H.4    Nose, A.5
  • 58
    • 34547951116 scopus 로고    scopus 로고
    • Wnt signaling positions neuromuscular connectivity by inhibiting synapse formation in C. elegans
    • The authors identify that Wnt signaling affects the localization of its receptor to negatively regulate synapse formation, and demonstrate with this a novel pathway that patterns synaptic connections.
    • Klassen M.P., and Shen K. Wnt signaling positions neuromuscular connectivity by inhibiting synapse formation in C. elegans. Cell 130 (2007) 704-716. The authors identify that Wnt signaling affects the localization of its receptor to negatively regulate synapse formation, and demonstrate with this a novel pathway that patterns synaptic connections.
    • (2007) Cell , vol.130 , pp. 704-716
    • Klassen, M.P.1    Shen, K.2
  • 59
    • 35148813033 scopus 로고    scopus 로고
    • Glia promote local synaptogenesis through UNC-6 (netrin) signaling in C. elegans
    • Colon-Ramos D.A., Margeta M.A., and Shen K. Glia promote local synaptogenesis through UNC-6 (netrin) signaling in C. elegans. Science 318 (2007) 103-106
    • (2007) Science , vol.318 , pp. 103-106
    • Colon-Ramos, D.A.1    Margeta, M.A.2    Shen, K.3
  • 60
    • 33847226897 scopus 로고    scopus 로고
    • GDNF and GFRalpha1 promote formation of neuronal synapses by ligand-induced cell adhesion
    • Ledda F., Paratcha G., Sandoval-Guzman T., and Ibanez C.F. GDNF and GFRalpha1 promote formation of neuronal synapses by ligand-induced cell adhesion. Nat Neurosci 10 (2007) 293-300
    • (2007) Nat Neurosci , vol.10 , pp. 293-300
    • Ledda, F.1    Paratcha, G.2    Sandoval-Guzman, T.3    Ibanez, C.F.4
  • 61
    • 25844504298 scopus 로고    scopus 로고
    • Signaling between glia and neurons: focus on synaptic plasticity
    • Allen N.J., and Barres B.A. Signaling between glia and neurons: focus on synaptic plasticity. Curr Opin Neurobiol 15 (2005) 542-548
    • (2005) Curr Opin Neurobiol , vol.15 , pp. 542-548
    • Allen, N.J.1    Barres, B.A.2
  • 62
    • 47049098701 scopus 로고    scopus 로고
    • N-WASP and the Arp2/3 complex are critical regulators of actin in the development of dendritic spines and synapses
    • Wegner A.M., Nebhan C.A., Hu L., Majumdar D., Meier K.M., Weaver A.M., and Webb D.J. N-WASP and the Arp2/3 complex are critical regulators of actin in the development of dendritic spines and synapses. J Biol Chem 283 (2008) 15912-15920
    • (2008) J Biol Chem , vol.283 , pp. 15912-15920
    • Wegner, A.M.1    Nebhan, C.A.2    Hu, L.3    Majumdar, D.4    Meier, K.M.5    Weaver, A.M.6    Webb, D.J.7
  • 63
    • 33749037455 scopus 로고    scopus 로고
    • NCAM promotes assembly and activity-dependent remodeling of the postsynaptic signaling complex
    • Sytnyk V., Leshchyns'ka I., Nikonenko A.G., and Schachner M. NCAM promotes assembly and activity-dependent remodeling of the postsynaptic signaling complex. J Cell Biol 174 (2006) 1071-1085
    • (2006) J Cell Biol , vol.174 , pp. 1071-1085
    • Sytnyk, V.1    Leshchyns'ka, I.2    Nikonenko, A.G.3    Schachner, M.4
  • 64
    • 42149171410 scopus 로고    scopus 로고
    • A presynaptic giant ankyrin stabilizes the NMJ through regulation of presynaptic microtubules and transsynaptic cell adhesion
    • Pielage J., Cheng L., Fetter R.D., Carlton P.M., Sedat J.W., and Davis G.W. A presynaptic giant ankyrin stabilizes the NMJ through regulation of presynaptic microtubules and transsynaptic cell adhesion. Neuron 58 (2008) 195-209
    • (2008) Neuron , vol.58 , pp. 195-209
    • Pielage, J.1    Cheng, L.2    Fetter, R.D.3    Carlton, P.M.4    Sedat, J.W.5    Davis, G.W.6
  • 66
    • 34748831111 scopus 로고    scopus 로고
    • MeCP2 controls excitatory synaptic strength by regulating glutamatergic synapse number
    • This study identifies that the transcriptional regulator MeCP2, which is mutated in Rett syndrome, regulates synapse number and transmission of glutamatergic neurons. This supports a link of this neurodevelopmental disorder to synaptogenesis.
    • Chao H.T., Zoghbi H.Y., and Rosenmund C. MeCP2 controls excitatory synaptic strength by regulating glutamatergic synapse number. Neuron 56 (2007) 58-65. This study identifies that the transcriptional regulator MeCP2, which is mutated in Rett syndrome, regulates synapse number and transmission of glutamatergic neurons. This supports a link of this neurodevelopmental disorder to synaptogenesis.
    • (2007) Neuron , vol.56 , pp. 58-65
    • Chao, H.T.1    Zoghbi, H.Y.2    Rosenmund, C.3
  • 68
    • 34250203570 scopus 로고    scopus 로고
    • GAD67-mediated GABA synthesis and signaling regulate inhibitory synaptic innervation in the visual cortex
    • Chattopadhyaya B., Di Cristo G., Wu C.Z., Knott G., Kuhlman S., Fu Y., Palmiter R.D., and Huang Z.J. GAD67-mediated GABA synthesis and signaling regulate inhibitory synaptic innervation in the visual cortex. Neuron 54 (2007) 889-903
    • (2007) Neuron , vol.54 , pp. 889-903
    • Chattopadhyaya, B.1    Di Cristo, G.2    Wu, C.Z.3    Knott, G.4    Kuhlman, S.5    Fu, Y.6    Palmiter, R.D.7    Huang, Z.J.8
  • 71
    • 33748100357 scopus 로고    scopus 로고
    • Spine growth precedes synapse formation in the adult neocortex in vivo
    • Knott G.W., Holtmaat A., Wilbrecht L., Welker E., and Svoboda K. Spine growth precedes synapse formation in the adult neocortex in vivo. Nat Neurosci 9 (2006) 1117-1124
    • (2006) Nat Neurosci , vol.9 , pp. 1117-1124
    • Knott, G.W.1    Holtmaat, A.2    Wilbrecht, L.3    Welker, E.4    Svoboda, K.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.