Platinated copper(3-clip-phen) complexes as effective DNA-cleaving and cytotoxic agents

Chemistry - A European Journal

Volumn 14, Issue 11, 2008, Pages 3418-3426

  Özalp Yaman, Şeniz ^a,b   De Hoog, Paul ^a   Amadei, Giulio ^c   Pitié, Marguerite ^c   Gamez, Patrick ^a   Dewelle, Janique ^d   Mijatovic, Tatjana ^d   Meunier, Bernard ^c   Kiss, Robert ^e   Reedijk, Jan ^a  

^a LEIDEN UNIVERSITY   (Netherlands)

^b ATILIM UNIVERSITY   (Turkey)

^c LCC LABORATOIRE DE CHIMIE DE COORDINATION   (France)

^d Unibioscreen SA   (Belgium)

^e UNIVERSITÉ LIBRE DE BRUXELLES   (Belgium)

Author keywords

Antitumor agents; Cis platin; DNA cleavage; Platinum; Primer extension

Indexed keywords

BIOCHEMISTRY; CELL CULTURE; CELLS; COMPLEXATION; COORDINATION REACTIONS; COPPER; COPPER COMPOUNDS; CYTOLOGY; DNA; GENES; LIGANDS; NUCLEIC ACIDS; ORGANIC ACIDS; PLATINUM;

ANTITUMOR AGENTS; CIS-PLATIN; DNA CLEAVAGE; PRIMER EXTENSION;

PLATINUM COMPOUNDS;

ANTINEOPLASTIC AGENT; COPPER; PLATINUM; VIRUS DNA;

ARTICLE; BACTERIOPHAGE PHI X 174; CHEMISTRY; DRUG SCREENING; GENETICS; HUMAN; HYDROLYSIS; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; NUCLEOTIDE SEQUENCE; TUMOR CELL LINE;

ANTINEOPLASTIC AGENTS; BACTERIOPHAGE PHI X 174; BASE SEQUENCE; CELL LINE, TUMOR; COPPER; DNA, VIRAL; DRUG SCREENING ASSAYS, ANTITUMOR; HUMANS; HYDROLYSIS; MAGNETIC RESONANCE SPECTROSCOPY; PLATINUM;

EID: 53849099656     PISSN: 09476539     EISSN: 15213765     Source Type: Journal    
DOI: 10.1002/chem.200702021     Document Type: Article

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