Combined cimetidine and temozolomide, compared with temozolomide alone: Significant increases in survival in nude mice bearing U373 human glioblastoma multiforme orthotopic xenografts

Journal of Neurosurgery

Volumn 102, Issue 4, 2005, Pages 706-714

  Lefranc, Florence ^b   James, Syril ^b   Camby, Isabelle ^b   Gaussin, Jean Franćois ^b   Darro, Francis ^b   Brotchi, Jacques ^b   Gabius, Joachim ^b   Kiss, Robert ^a  

^a UNIVERSITÉ LIBRE DE BRUXELLES   (Belgium)

^b NONE

Author keywords

Cimetidine; Glioma; Mouse; Orthotopic xenograft; Quantitative glycohistochemistry; Survival analysis; Temozolomide

Indexed keywords

AMINE; ANTIINFLAMMATORY AGENT; ANTINEOPLASTIC AGENT; CIMETIDINE; CYTOTOXIC AGENT; FUCOSE; RECEPTOR SUBUNIT; TEMOZOLOMIDE; TETRAZOLIUM; ALKYLATING AGENT; DACARBAZINE; DRUG DERIVATIVE; IMMUNOLOGICAL ADJUVANT;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER CELL CULTURE; CANCER COMBINATION CHEMOTHERAPY; CANCER SURVIVAL; CELL ADHESION; CELL ASSAY; CELL MIGRATION; COLORIMETRY; COMPARATIVE STUDY; COMPUTER ASSISTED DIAGNOSIS; CONTROLLED STUDY; DRUG EFFECT; DRUG EFFICACY; DRUG MECHANISM; GLIOBLASTOMA; GLIOSARCOMA; HISTOCHEMISTRY; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; MALE; MICROSCOPY; MONOTHERAPY; MOUSE; NONHUMAN; NUDE MOUSE; PRIORITY JOURNAL; RAT; RECEPTOR INTRINSIC ACTIVITY; TUMOR GROWTH; TUMOR XENOGRAFT; ANIMAL; ANIMAL DISEASE; BRAIN TUMOR; FEMALE; PATHOLOGY; XENOGRAFT;

ADJUVANTS, IMMUNOLOGIC; ANIMALS; ANTINEOPLASTIC AGENTS, ALKYLATING; BRAIN NEOPLASMS; CIMETIDINE; DACARBAZINE; FEMALE; GLIOBLASTOMA; MICE; MICE, NUDE; TRANSPLANTATION, HETEROLOGOUS;

EID: 18744397231     PISSN: 00223085     EISSN: 00223085     Source Type: Journal    
DOI: 10.3171/jns.2005.102.4.0706     Document Type: Article

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