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Volumn 45, Issue 12, 2002, Pages 2543-2555
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3-Aryl-2-quinolone derivatives: Synthesis and characterization of in vitro and in vivo antitumor effects with emphasis on a new therapeutical target connected with cell migration
a
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Author keywords
[No Author keywords available]
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Indexed keywords
1 [2 (1H 1,2,3,4 TETRAZOL 5 YL)ETHYL] 5,7 DIMETHOXY 3 (4 METHOXYPHENYL) 1,2 DIHYDRO 2 QUINOLINONE;
1 [3 (DIMETHYLAMINO)PROPYL] 5,7 DIMETHOXY 3 (4 METHOXYPHENYL) 1,2 DIHYDRO 2 QUINOLINONE;
3 [5,7 DIMETHOXY 3 (4 METHOXYPHENYL) 2 OXO 1,2 DIHYDRO 1 QUINOLINYL]PROPANENITRILE;
5,7 DIMETHOXY 3 (4 METHOXYPHENYL) 1 METHYL 1,2 DIHYDRO 2 QUINOLINONE 2 PHENYLHYDRAZONE;
ANTINEOPLASTIC AGENT;
CYTOTOXIC AGENT;
DOXORUBICIN;
ETOPOSIDE;
QUINOLINE DERIVATIVE;
UNCLASSIFIED DRUG;
ANIMAL EXPERIMENT;
ANIMAL MODEL;
ANIMAL TISSUE;
ANTINEOPLASTIC ACTIVITY;
ARTICLE;
BREAST CARCINOMA;
CANCER CELL CULTURE;
CANCER COMBINATION CHEMOTHERAPY;
CANCER GROWTH;
CELL MIGRATION;
CELL STRAIN MCF 7;
COLORIMETRY;
COMPUTER ANALYSIS;
CONCENTRATION RESPONSE;
CONTROLLED STUDY;
DOSE CALCULATION;
DRUG CYTOTOXICITY;
DRUG EFFICACY;
DRUG POTENTIATION;
DRUG SCREENING;
DRUG SYNTHESIS;
DRUG TARGETING;
DRUG TOLERABILITY;
HUMAN;
HUMAN CELL;
IC 50;
IN VITRO STUDY;
IN VIVO STUDY;
NONHUMAN;
PHASE CONTRAST MICROSCOPY;
QUANTITATIVE ANALYSIS;
ADENOCARCINOMA;
ANIMALS;
ANTINEOPLASTIC AGENTS;
CELL MOVEMENT;
DOXORUBICIN;
DRUG SCREENING ASSAYS, ANTITUMOR;
DRUG SYNERGISM;
ETOPOSIDE;
FEMALE;
HUMANS;
MAMMARY NEOPLASMS, EXPERIMENTAL;
MICE;
MICROSCOPY, PHASE-CONTRAST;
NEOPLASM TRANSPLANTATION;
QUINOLONES;
STRUCTURE-ACTIVITY RELATIONSHIP;
TETRAZOLES;
TUMOR CELLS, CULTURED;
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EID: 0037030607
PISSN: 00222623
EISSN: None
Source Type: Journal
DOI: 10.1021/jm010978m Document Type: Article |
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Times cited : (167)
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References (38)
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