p38 and c-Jun N-terminal kinase mitogen-activated protein kinase signaling pathways play distinct roles in the response of organogenesis-stage embryos to a teratogen

Journal of Pharmacology and Experimental Therapeutics

Volumn 326, Issue 3, 2008, Pages 764-772

  Yan, Jin ^a   Hales, Barbara F ^a  

^a MCGILL UNIVERSITY   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; HYDROXYUREA; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE P38; STRESS ACTIVATED PROTEIN KINASE; IMIDAZOLE DERIVATIVE; MITOGEN ACTIVATED PROTEIN KINASE; PYRIDINE DERIVATIVE; TERATOGENIC AGENT;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BRAIN MALFORMATION; CONTROLLED STUDY; DEFORMITY; DOSE RESPONSE; ECTRODACTYLY; EYE MALFORMATION; FEMALE; FETUS MORTALITY; FETUS WEIGHT; GASTROSCHISIS; GROWTH RETARDATION; HEMIMELIA; MOUSE; NONHUMAN; ORGANOGENESIS; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; SKELETON MALFORMATION; SPINA BIFIDA; TERATOGENICITY; WESTERN BLOTTING; ANIMAL; ANIMAL EMBRYO; ANTAGONISTS AND INHIBITORS; COMPARATIVE STUDY; CONGENITAL MALFORMATION; DRUG EFFECTS; EMBRYOLOGY; ENZYMOLOGY; PHYSIOLOGY; PREGNANCY;

ABNORMALITIES, DRUG-INDUCED; ANIMALS; EMBRYO, MAMMALIAN; FEMALE; IMIDAZOLES; JNK MITOGEN-ACTIVATED PROTEIN KINASES; MAP KINASE SIGNALING SYSTEM; MICE; MITOGEN-ACTIVATED PROTEIN KINASES; ORGANOGENESIS; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PREGNANCY; PYRIDINES; TERATOGENS;

EID: 53849091727     PISSN: 00223565     EISSN: 15210103     Source Type: Journal    
DOI: 10.1124/jpet.108.139907     Document Type: Article

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