메뉴 건너뛰기




Volumn 53, Issue 11, 2008, Pages 2989-2994

Beneficial effects of fluvastatin on liver microcirculation and regeneration after massive hepatectomy in rats

Author keywords

Fluvastatin; Hepatectomy; Hepatic sinusoid; Liver failure; Liver regeneration; Reactive oxygen species; Reperfusion injury; Rho; Stellate cells

Indexed keywords

ALPHA SMOOTH MUSCLE ACTIN; BILIRUBIN; FLUINDOSTATIN;

EID: 53849091001     PISSN: 01632116     EISSN: None     Source Type: Journal    
DOI: 10.1007/s10620-008-0241-y     Document Type: Article
Times cited : (17)

References (38)
  • 3
    • 33645799492 scopus 로고    scopus 로고
    • Mechanisms of Liver Injury. I. TNF-alpha-induced liver injury: Role of IKK, JNK, and ROS pathways
    • doi: 10.1152/ajpgi.00422.2005
    • Schwabe RF, Brenner DA (2006) Mechanisms of Liver Injury. I. TNF-alpha-induced liver injury: role of IKK, JNK, and ROS pathways. Am J Physiol Gastrointest Liver Physiol 290:583-589. doi: 10.1152/ajpgi.00422.2005
    • (2006) Am J Physiol Gastrointest Liver Physiol , vol.290 , pp. 583-589
    • Schwabe, R.F.1    Brenner, D.A.2
  • 4
    • 3142657270 scopus 로고    scopus 로고
    • Molecular process in acute liver injury and regeneration induced by carbon tetrachloride
    • doi: 10.1016/j.lfs.2004.02.030
    • Taniguchi M, Takeuchi T, Nakatsuka R, Watanabe T, Sato K (2004) Molecular process in acute liver injury and regeneration induced by carbon tetrachloride. Life Sci 75:1539-1549 doi: 10.1016/j.lfs.2004.02.030
    • (2004) Life Sci , vol.75 , pp. 1539-1549
    • Taniguchi, M.1    Takeuchi, T.2    Nakatsuka, R.3    Watanabe, T.4    Sato, K.5
  • 6
    • 34250328345 scopus 로고    scopus 로고
    • Role of reactive oxygen species in mediating hepatic ischemia-reperfusion injury and its therapeutic applications in liver transplantation
    • doi: 10.1016/j.transproceed.2006.11.021
    • Zhang W, Wang M, Xie HY, Zhou L, Meng XQ, Shi J, Zheng S (2007) Role of reactive oxygen species in mediating hepatic ischemia-reperfusion injury and its therapeutic applications in liver transplantation. Transplant Proc 39:1332-1337 doi: 10.1016/j.transproceed.2006.11.021
    • (2007) Transplant Proc , vol.39 , pp. 1332-1337
    • Zhang, W.1    Wang, M.2    Xie, H.Y.3    Zhou, L.4    Meng, X.Q.5    Shi, J.6    Zheng, S.7
  • 8
    • 33644834412 scopus 로고    scopus 로고
    • The role of Rho-associated kinase in differential regulation by statins of interleukin-1β- and lipopolysaccharide-mediated nuclear factor κb activation and inducible nitric-oxide synthase gene expression in vascular smooth muscle cells
    • CY Wei KC Huang YH Chou PF Hsieh KH Lin WW Lin 2006 The role of Rho-associated kinase in differential regulation by statins of interleukin-1β- and lipopolysaccharide-mediated nuclear factor κB activation and inducible nitric-oxide synthase gene expression in vascular smooth muscle cells Mol Pharmacol 69 960 967
    • (2006) Mol Pharmacol , vol.69 , pp. 960-967
    • Wei, C.Y.1    Huang, K.C.2    Chou, Y.H.3    Hsieh, P.F.4    Lin, K.H.5    Lin, W.W.6
  • 9
    • 3242766006 scopus 로고    scopus 로고
    • Statin blocks Rho/Rho-kinase signalling and disrupts the actin cytoskeleton: Relationship to enhancement of LPS-mediated nitric oxide synthesis in vascular smooth muscle cells
    • T Kato H Hashikabe C Iwata K Akimoto Y Hattori 2004 Statin blocks Rho/Rho-kinase signalling and disrupts the actin cytoskeleton: relationship to enhancement of LPS-mediated nitric oxide synthesis in vascular smooth muscle cells Biochim Biophys Acta 1689 267 272
    • (2004) Biochim Biophys Acta , vol.1689 , pp. 267-272
    • Kato, T.1    Hashikabe, H.2    Iwata, C.3    Akimoto, K.4    Hattori, Y.5
  • 10
    • 2442434564 scopus 로고    scopus 로고
    • Apoptotic injury in cultured human hepatocytes induced by HMG-CoA reductase inhibitors
    • doi:10.1016/j.bcp.2004.02.037
    • Kubota T, Fujisaki K, Itoh Y, Yano T, Sendo T, Oishi R (2004) Apoptotic injury in cultured human hepatocytes induced by HMG-CoA reductase inhibitors. Biochem Pharmacol 67:2175-2186 doi: 10.1016/j.bcp.2004.02.037
    • (2004) Biochem Pharmacol , vol.67 , pp. 2175-2186
    • Kubota, T.1    Fujisaki, K.2    Itoh, Y.3    Yano, T.4    Sendo, T.5    Oishi, R.6
  • 12
    • 0035572718 scopus 로고    scopus 로고
    • Pleiotropic effect of 3-hydroxy-3-methylalutaryl coenzyme a reductase inhibitors
    • doi: 10.1161/hq1101.098486
    • Takemoto M, Liao JK (2001) Pleiotropic effect of 3-hydroxy-3- methylalutaryl coenzyme a reductase inhibitors. Arterioscler Thromb Vasc Biol 21:1712-1719 doi: 10.1161/hq1101.098486
    • (2001) Arterioscler Thromb Vasc Biol , vol.21 , pp. 1712-1719
    • Takemoto, M.1    Liao, J.K.2
  • 13
    • 7644242146 scopus 로고    scopus 로고
    • Effect of statins on endothelium and signaling mechanisms
    • doi: 10.1161/01.STR.0000143319.73503.38
    • Endres M, Laufs U (2004) Effect of statins on endothelium and signaling mechanisms. Stroke 35:2708-2711 doi: 10.1161/01.STR.0000143319.73503.38
    • (2004) Stroke , vol.35 , pp. 2708-2711
    • Endres, M.1    Laufs, U.2
  • 14
    • 0035838952 scopus 로고    scopus 로고
    • Inhibitory effects of fluvastatin and its metabolites on the formation of several reactive oxygen species
    • doi: 10.1016/S0024-3205(01)01223-1
    • Nakashima A, Ohtawa M, Iwasaki K, Wada M, Kuroda N, Nakashima K (2001) Inhibitory effects of fluvastatin and its metabolites on the formation of several reactive oxygen species. Life Sci 69:1381-1389 doi: 10.1016/S0024- 3205(01)01223-1
    • (2001) Life Sci , vol.69 , pp. 1381-1389
    • Nakashima, A.1    Ohtawa, M.2    Iwasaki, K.3    Wada, M.4    Kuroda, N.5    Nakashima, K.6
  • 15
    • 33745903898 scopus 로고    scopus 로고
    • Different Anti-HCV profiles of statins and their potential for combination therapy with interferon
    • doi: 10.1002/hep.21232
    • Ikeda M, Abe K, Yamada M, Dansako H, Naka K, Kato N (2006) Different Anti-HCV profiles of statins and their potential for combination therapy with interferon. Hepatology 44:117-125 doi: 10.1002/hep.21232
    • (2006) Hepatology , vol.44 , pp. 117-125
    • Ikeda, M.1    Abe, K.2    Yamada, M.3    Dansako, H.4    Naka, K.5    Kato, N.6
  • 16
    • 0001276586 scopus 로고
    • Experimental pathology of the liver. I. Restoration of the liver of the white rat following partial surgical removal
    • GM Higgins RM Anderson 1931 Experimental pathology of the liver. I. Restoration of the liver of the white rat following partial surgical removal Arch Pathol 12 186 202
    • (1931) Arch Pathol , vol.12 , pp. 186-202
    • Higgins, G.M.1    Anderson, R.M.2
  • 18
    • 0022318457 scopus 로고
    • Cholesterol metabolism in regenerating liver of the rat
    • FJ Field SN Mathur DR LaBrecque 1985 Cholesterol metabolism in regenerating liver of the rat Am J Physiol 249 G679 G684
    • (1985) Am J Physiol , vol.249
    • Field, F.J.1    Mathur, S.N.2    Labrecque, D.R.3
  • 20
    • 0036150495 scopus 로고    scopus 로고
    • Influence of high cholesterol diet and pravastatin sodium on the initiation of liver regeneration in rats after partial hepatectomy
    • doi:10.1016/S0899-9007(01)00678-5
    • Zivna H, Zivny P, Palicka V, Simakova E (2002) Influence of high cholesterol diet and pravastatin sodium on the initiation of liver regeneration in rats after partial hepatectomy. Nutrition 18:51-55. doi:10.1016/S0899- 9007(01)00678-5
    • (2002) Nutrition , vol.18 , pp. 51-55
    • Zivna, H.1    Zivny, P.2    Palicka, V.3    Simakova, E.4
  • 21
    • 0032466156 scopus 로고    scopus 로고
    • Evidence of nitric oxide, a flow-dependent factor, being a trigger of liver regeneration in rats
    • doi: 10.1139/cjpp-76-12-1072
    • Wang HH, Lautt WW (1998) Evidence of nitric oxide, a flow-dependent factor, being a trigger of liver regeneration in rats. Can J Physiol Pharmacol 76:1072-1079 doi: 10.1139/cjpp-76-12-1072
    • (1998) Can J Physiol Pharmacol , vol.76 , pp. 1072-1079
    • Wang, H.H.1    Lautt, W.W.2
  • 23
    • 29744438007 scopus 로고    scopus 로고
    • The effect of amrinone on liver regeneration in experimental hepatic resection model
    • doi: 10.1016/j.jss.2005.07.020
    • Akcan A, Kucuk C, Ok E, Canoz O, Muhtaroglu S, Yilmaz N, Yilmaz Z (2006) The effect of amrinone on liver regeneration in experimental hepatic resection model. J Surg Res 130:66-72 doi: 10.1016/j.jss.2005.07.020
    • (2006) J Surg Res , vol.130 , pp. 66-72
    • Akcan, A.1    Kucuk, C.2    Ok, E.3    Canoz, O.4    Muhtaroglu, S.5    Yilmaz, N.6    Yilmaz, Z.7
  • 24
    • 34548385362 scopus 로고    scopus 로고
    • Hepatic stellate cells and oxidative stress
    • R Urtasun N Nieto 2007 Hepatic stellate cells and oxidative stress Rev Esp Enferm Dig 99 223 230
    • (2007) Rev Esp Enferm Dig , vol.99 , pp. 223-230
    • Urtasun, R.1    Nieto, N.2
  • 25
    • 0036139102 scopus 로고    scopus 로고
    • Stimulation and proliferation of primary rat hepatic stellate cells by cytochrome P450 2E1-derived reactive oxygen species
    • doi: 10.1053/jhep.2002.30362
    • Nieto N, Friedman SL, Cederbaum AI (2002) Stimulation and proliferation of primary rat hepatic stellate cells by cytochrome P450 2E1-derived reactive oxygen species. Hepatology 35:62-73 doi: 10.1053/jhep.2002.30362
    • (2002) Hepatology , vol.35 , pp. 62-73
    • Nieto, N.1    Friedman, S.L.2    Cederbaum, A.I.3
  • 26
    • 0032835657 scopus 로고    scopus 로고
    • CYP2E1-mediated oxidative stress induces collagen type I expression in rat hepatic stellate cells
    • doi: 10.1002/hep.510300433
    • Nieto N, Friedman SL, Greenwel P, Cederbaum AI (1999) CYP2E1-mediated oxidative stress induces collagen type I expression in rat hepatic stellate cells. Hepatology 30:987-996 doi: 10.1002/hep.510300433
    • (1999) Hepatology , vol.30 , pp. 987-996
    • Nieto, N.1    Friedman, S.L.2    Greenwel, P.3    Cederbaum, A.I.4
  • 27
    • 15744405797 scopus 로고    scopus 로고
    • Signal transduction pathways leading to increased eIF4E phosphorylation caused by oxidative stress
    • doi: 10.1016/j.freeradbiomed.2004.09.034
    • Duncan RF, Peterson H, Sevanian A (2005) Signal transduction pathways leading to increased eIF4E phosphorylation caused by oxidative stress. Free Radic Biol Med 38:631-643 doi: 10.1016/j.freeradbiomed.2004.09.034
    • (2005) Free Radic Biol Med , vol.38 , pp. 631-643
    • Duncan, R.F.1    Peterson, H.2    Sevanian, A.3
  • 29
    • 0033854016 scopus 로고    scopus 로고
    • Inhibition of transforming growth factor beta prevents progression of liver fibrosis and enhances hepatocyte regeneration in dimethylnitrosamine- treated rats
    • doi: 10.1053/jhep.2000.9109
    • Nakamura T, Sakata R, Ueno T, Sata M, Ueno H (2000) Inhibition of transforming growth factor beta prevents progression of liver fibrosis and enhances hepatocyte regeneration in dimethylnitrosamine-treated rats. Hepatology 32:247-255 doi: 10.1053/jhep.2000.9109
    • (2000) Hepatology , vol.32 , pp. 247-255
    • Nakamura, T.1    Sakata, R.2    Ueno, T.3    Sata, M.4    Ueno, H.5
  • 30
    • 7044228192 scopus 로고    scopus 로고
    • Intact signaling by transforming growth factor beta is not required for termination of liver regeneration in mice
    • doi: 10.1002/hep.20426
    • Oe S, Lemmer ER, Conner EA, Factor VM, Leveen P, Larsson J, Karlsson S, Thorgeirsson SS (2004) Intact signaling by transforming growth factor beta is not required for termination of liver regeneration in mice. Hepatology 40:1098-1105 doi: 10.1002/hep.20426
    • (2004) Hepatology , vol.40 , pp. 1098-1105
    • Oe, S.1    Lemmer, E.R.2    Conner, E.A.3    Factor, V.M.4    Leveen, P.5    Larsson, J.6    Karlsson, S.7    Thorgeirsson, S.S.8
  • 32
    • 1242336976 scopus 로고    scopus 로고
    • Uncoupling protein-2 deficiency promotes oxidant stress and delays liver regeneration in mice
    • doi: 10.1002/hep.20047
    • Horimoto M, Fulop P, Derdak Z, Wands JR, Baffy G (2004) Uncoupling protein-2 deficiency promotes oxidant stress and delays liver regeneration in mice. Hepatology 39:386-392 doi: 10.1002/hep.20047
    • (2004) Hepatology , vol.39 , pp. 386-392
    • Horimoto, M.1    Fulop, P.2    Derdak, Z.3    Wands, J.R.4    Baffy, G.5
  • 33
    • 0033433975 scopus 로고    scopus 로고
    • Effect of ethanol on tumor necrosis factor signaling during liver regeneration
    • doi: 10.1016/S0009-9120(99)00057-0
    • Diehl AM (1999) Effect of ethanol on tumor necrosis factor signaling during liver regeneration. Clin Biochem 32:571-578 doi: 10.1016/S0009-9120(99) 00057-0
    • (1999) Clin Biochem , vol.32 , pp. 571-578
    • Diehl, A.M.1
  • 34
    • 0034655373 scopus 로고    scopus 로고
    • 2 response of normal human fibroblasts
    • doi: 10.1042/0264-6021:3470543
    • 2 response of normal human fibroblasts. Biochem J 347:543-551 doi: 10.1042/0264-6021:3470543
    • (2000) Biochem J , vol.347 , pp. 543-551
    • Chen, Q.M.1    Liu, J.2    Merrett, J.B.3
  • 35
    • 0037133928 scopus 로고    scopus 로고
    • H2O2 induces a transient multi-phase cell cycle arrest in mouse fibroblasts through modulating cyclin D and p21Cip1 expression
    • doi: 10.1074/jbc.M111123200
    • Barnouin K, Dubuisson ML, Child ES, Fernandez de Mattos S, Glassford J, Medema RH, Mann DJ, Lam EW (2002) H2O2 induces a transient multi-phase cell cycle arrest in mouse fibroblasts through modulating cyclin D and p21Cip1 expression. J Biol Chem 277:13761-13770 doi: 10.1074/jbc.M111123200
    • (2002) J Biol Chem , vol.277 , pp. 13761-13770
    • Barnouin, K.1    Dubuisson, M.L.2    Child, E.S.3    Fernandez De Mattos, S.4    Glassford, J.5    Medema, R.H.6    Mann, D.J.7    Lam, E.W.8
  • 36
    • 33847147603 scopus 로고    scopus 로고
    • The role of ROS in microcystin-LR-induced hepatocyte apoptosis and liver injury in mice
    • doi: 10.1016/j.tox.2006.12.010
    • Weng D, Lu Y, Wei Y, Liu Y, Shen P (2007) The role of ROS in microcystin-LR-induced hepatocyte apoptosis and liver injury in mice. Toxicology 22:15-23. doi: 10.1016/j.tox.2006.12.010
    • (2007) Toxicology , vol.22 , pp. 15-23
    • Weng, D.1    Lu, Y.2    Wei, Y.3    Liu, Y.4    Shen, P.5
  • 37
    • 34250004335 scopus 로고    scopus 로고
    • Fluvastatin ameliorates endotoxin induced multiple organ failure in conscious rats
    • doi: 10.1016/j.resuscitation.2006.12.002
    • Chen CH, Lee RP, Wu WT, Liao KW, Hsu N, Hsu BG (2007) Fluvastatin ameliorates endotoxin induced multiple organ failure in conscious rats. Resuscitation 74:166-174 doi: 10.1016/j.resuscitation.2006.12.002
    • (2007) Resuscitation , vol.74 , pp. 166-174
    • Ch, C.1    Lee, R.P.2    Wu, W.T.3    Liao, K.W.4    Hsu, N.5    Hsu, B.G.6
  • 38
    • 0037457959 scopus 로고    scopus 로고
    • Sexual dimorphism in reduced-size liver ischemia and reperfusion injury in mice: Role of endothelial cell nitric oxide synthase
    • doi: 10.1073/pnas.0235680100
    • Harada H, Pavlick KP, Hines IN, Lefer DJ, Hoffman JM, Bharwani S, Wolf RE, Grisham MB (2003) Sexual dimorphism in reduced-size liver ischemia and reperfusion injury in mice: role of endothelial cell nitric oxide synthase. Proc Natl Acad Sci USA 21:739-744. doi: 10.1073/pnas.0235680100
    • (2003) Proc Natl Acad Sci USA , vol.21 , pp. 739-744
    • Harada, H.1    Kp, P.2    Hines, I.N.3    Lefer, D.J.4    Hoffman, J.M.5    Bharwani, S.6    Wolf, R.E.7    Grisham, M.B.8


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.