Role of Reactive Oxygen Species in Mediating Hepatic Ischemia-Reperfusion Injury and Its Therapeutic Applications in Liver Transplantation

Transplantation Proceedings

Volumn 39, Issue 5, 2007, Pages 1332-1337

  Zhang, W ^a   Wang, M ^b   Xie, H Y ^a   Zhou, L ^a   Meng, X Q ^a   Shi, J ^a   Zheng, S ^a  

^a BEIJING HOSPITAL   (China)

^b YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALLOPURINOL; ALPHA TOCOPHEROL; ANTIOXIDANT; ASCORBIC ACID; CATALASE; DEHYDROASCORBIC ACID; EBSELEN; FASUDIL; GAMMA INTERFERON; GLUTATHIONE PEROXIDASE; GRANULOCYTE COLONY STIMULATING FACTOR; HYDROGEN PEROXIDE; HYDROXYL RADICAL; IDEBENONE; INTERCELLULAR ADHESION MOLECULE 1; INTERLEUKIN 1; LEFLUNOMIDE; LYMPHOTOXIN; MESNA; PEROXIREDOXIN; POLYENE PHOSPHATIDYLCHOLINE; REACTIVE OXYGEN METABOLITE; RESVERATROL; SUPEROXIDE; SUPEROXIDE DISMUTASE; TEMPOL; THIOREDOXIN; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; UNINDEXED DRUG; XANTHINE OXIDASE;

ANTIOXIDANT ACTIVITY; ARTICLE; CD4+ T LYMPHOCYTE; CELL DAMAGE; DRUG MECHANISM; ENZYME ACTIVITY; ENZYME INHIBITION; HEMORRHAGIC SHOCK; HUMAN; KUPFFER CELL; LIPID PEROXIDATION; LIVER CELL; LIVER FAILURE; LIVER GRAFT; LIVER INJURY; LIVER ISCHEMIA; LIVER TRANSPLANTATION; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; REPERFUSION INJURY;

ANTIOXIDANTS; ASCORBIC ACID; FREE RADICAL SCAVENGERS; GLUTATHIONE PEROXIDASE; HUMANS; ISCHEMIC PRECONDITIONING; LIVER CIRCULATION; LIVER FAILURE; LIVER TRANSPLANTATION; PEROXIDASES; REACTIVE OXYGEN SPECIES; REPERFUSION INJURY; THIOREDOXIN;

EID: 34250328345     PISSN: 00411345     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.transproceed.2006.11.021     Document Type: Article

References (62)

1. Fellstrom B., Akuyrek L.M., Backman U., et al. Postischemic reperfusion injury and allograft arteriosclerosis. Transplant Proc 308 (1998) 4278
2. Carden D.L., and Granger D.N. Pathophysiology of ischaemia-reperfusion injury. J Pathol 190 (2000) 255
3. Jaeschke H., and Farhood A. Neutrophil and Kupffer cell-induced oxidant stress and ischemia-reperfusion injury in rat liver in vivo. Am J Physiol 260 (1991) G355
4. Jaeschke H. Molecular mechanisms of hepatic ischemia-reperfusion injury and preconditioning. Am J Physiol Gastrointest Liver Physiol 284 (2003) G15
5. Colletti L.M., Remick D.G., Burtch G.D., et al. Role of tumor necrosis factor-alpha in the pathophysiologic alterations after hepatic ischemia/reperfusion injury in the rat. J Clin Invest 856 (1990) 1936
6. Granger D.N., and Kubes P. The microcirculation and inflammation: modulation of leukocyte-endothelial cell adhesion. J Leukoc Biol 555 (1994) 662
7. Essani N.A., Fisher M.A., Farhood A., et al. Cytokine-induced upregulation of hepatic intercellular adhesion molecule-1 messenger RNA expression and its role in the pathophysiology of murine endotoxin shock and acute liver failure. Hepatology 216 (1995) 1632
8. Wheeler M.D. Endotoxin and Kupffer cell activation in alcoholic liver disease. Alcohol Res Health 274 (2003) 300
9. Mosher B., Dean R., Harkema J., et al. Inhibition of chemokines production by Kupffer cells decreased hepatic ischemia/reperfusion injury in mice. J Surg Res 992 (2001) 201
10. Bilzer M., Jaeschke H., Vollmar A.M., et al. Prevention of Kupffer cell-induced oxidant injury in rat liver by atrial natriuretic peptide. Am J Physiol 2761 (1999) G1137
11. Nonn L., Berggren M., and Powis G. Increased expression of mitochondrial peroxiredoxin-3 (thioredoxin peroxidase-2) protects cancer cells against hypoxia and drug-induced hydrogen peroxide-dependent apoptosis. Mol Cancer Res 19 (2003) 682
12. Corradini S.G., Micheletta F., Natoli S., et al. High preoperative recipient plasma 7beta-hydroxycholesterol is associated with initial poor graft function after liver transplantation. Liver Transpl 1112 (2005) 1494
13. Shen H.M., Shi C.Y., Shen Y., et al. Detection of elevated reactive oxygen species level in cultured rat hepatocytes treated with aflatoxin B1. Free Radic Biol Med 212 (1996) 139
14. Leutner S., Schindowski K., Frolich L., et al. Enhanced ROS-generation in lymphocytes from Alzheimer's patients. Pharmacopsychiatry 386 (2005) 312
15. Arrigo A.P., Firdaus W.J., Mellier G., et al. Cytotoxic effects induced by oxidative stress in cultured mammalian cells and protection provided by Hsp27 expression. Methods 352 (2005) 126
16. Hassan L., Bueno P., Ferron-Celma I., et al. Time course of antioxidant enzyme activities in liver transplant recipients. Transplant Proc 379 (2005) 3932
17. Mota-Filipe H., McDonald M.C., Cuzzocrea S., et al. A membrane-permeable radical scavenger reduces the organ injury in hemorrhagic shock. Shock 124 (1999) 255
18. Yabe Y., Koyama Y., Nishikawa M., et al. Hepatocyte-specific distribution of catalase and its inhibitory effect on hepatic ischemia/reperfusion injury in mice. Free Radic Res 304 (1999) 265
19. Jaeschke H. Reactive oxygen and ischemia/reperfusion injury of the liver. Chem Biol Interact 79 (1991) 115
20. Rhee S.G., Kang S.W., Chang T.S., et al. Peroxiredoxin, a novel family of peroxidases. IUBMB Life 522 (2001) 35
21. Shau H., Merino A., Chen L., et al. Induction of peroxiredoxins in transplanted livers and demonstration of their in vitro cytoprotection activity. Antioxid Redox Signal 22 (2000) 347
22. Vertuani S., Angusti A., and Manfredini S. The antioxidants and pro-antioxidants network: An overview. Curr Pharm Des 10 (2004) 1677
23. Spyrou G., Enmark E., Miranda-Vizuete A., et al. Cloning and expression of a novel mammalian thioredoxin. J Biol Chem 2725 (1997) 2936
24. Seung-Rock L., Jae-Ryong K., Ki-Sun K., et al. Molecular cloning and characterization of a mitochondrial selenocysteine-containing thioredoxin reductase from rat. Liver J Biol Chem 2748 (1999) 4722
25. Gressier B., Lebegue S., Brunet C., et al. Pro-oxidant properties of methotrexate: evaluation and prevention by an anti-oxidant drug. Pharmazie 499 (1994) 679
26. Sener G., Sehirli O., Ercan F., et al. Protective effect of MESNA (2-mercaptoethane sulfonate) against hepatic ischemia/reperfusion injury in rats. Surg Today 357 (2005) 575
27. Tadolini C., Juliano L., Piu F., et al. Resveratrol inhibition of lipid peroxidation. Free Radic Res 33 (2000) 105
28. López-Vélez M., Martínez-Martínez F., and Del Valle-Ribes C. The study of phenolic compounds as natural antioxidants in wine. Crit Rev Food Sci Nutr 43 (2003) 233
29. Leonard S.S., Xia C., Jiang B.H., et al. Resveratrol scavenges reactive oxygen species and effects radical-induced cellular responses. Biochem Biophys Res Commun 309 (2003) 1017
30. Plina C., Tillementa J.-P., Berdeauxa A., et al. Resveratrol protects against cold ischemia-warm reoxygenation-induced damages to mitochondria and cells in rat liver. Eur J Pharm 528 (2005) 162
31. Bodanes R.S., and Chan P.C. Ascorbic acid as a scavenger of singlet oxygen. FEBS Lett 105 (1979) 195
32. De Tata V., Brizzi S., Saviozzi M., et al. Protective role of dehydroascorbate in rat liver ischemia-reperfusion injury. J Surg Res 123 (2005) 215
33. Sener G., Sehirli O., Ipci Y., et al. Aqueous garlic extract alleviates ischaemia-reperfusion-induced oxidative hepatic injury in rats. J Pharm Pharmacol 571 (2005) 145
34. Casini A., Ceni E., Salzano R., et al. Neutrophil-derived superoxide anion induces lipid peroxidation and stimulates collagen synthesis in human hepatic stellate cells: role of nitric oxide. Hepatology 252 (1997) 361
35. Wink D.A., Miranda K.M., Espey M.G., et al. Mechanisms of the antioxidant effects of nitric oxide. Antioxid Redox Signal 32 (2001) 203
36. Ben Mosbah I, Rosello-Catafau J, Franco-Gou R, et al: Preservation of steatotic livers in IGL-1 solution. Liver Transpl (in press)
37. Yi-He L., Liebes L., Yiyu Z., et al. Reactive oxygen species generation and mitochondrial dysfunction in the apoptotic response to bortezomib, a novel proteasome inhibitor, in human H460 non-small cell lung cancer cells. J Biol Chem 278 (2003) 33714
38. Young T.A., Cunningham C.C., and Bailey S.M. Reactive oxygen species production by the mitochondrial respiratory chain in isolated rat hepatocytes and liver mitochondria: studies using myxothiazol. Arch Biochem Biophys 4051 (2002) 65
39. Loftis L.L., Johanns C.A., Lechner A.J., et al. Brief hypoxic stress suppresses postbacteremic NF-κ B activation and TNF-α bioactivity in perfused liver. Am J Physiol Regul Integr Comp Physiol 279 (2000) R99
40. Ozaki M., Deshpande S.S., Angkeow P., et al. Inhibition of the Rac1 GTPase protects against nonlethal ischemia/reperfusion-induced necrosis and apoptosis in vivo. FASEB J 14 (2000) 418
41. Harada N., Iimuro Y., Nitta T., et al. Inactivation of the small GTPase Rac1 protects the liver from ischemia/reperfusion injury in the rat. Surgery 1343 (2003) 480
42. Shiotani S., Shimada M., Suehiro T., et al. Involvement of Rho-kinase in cold ischemia-reperfusion injury after liver transplantation in rats. Transplantation 783 (2004) 375
43. Yerushalmi B., Dahl R., Devereaux M.W., et al. Bile acid-induced rat hepatocyte apoptosis is inhibited by antioxidants and blockers of the mitochondrial permeability transition. Hepatology 333 (2001) 616
44. Karaman A., Fadillioglu E., Turkmen E., et al. Protective effects of leflunomide against ischemia-reperfusion injury of the rat liver. Pediatr Surg Int 22 (2006) 428
45. Demirbilek S, Karaman A, Gurunluoglu K, et al: Polyenylphosphatidylcholine pretreatment protects rat liver from ischemia/reperfusion injury. Hepatol Res (in press)
46. Morham S.G., Langenbach R., and Loftin C.D. Prostaglandin synthase 2 gene disruption causes severe renal pathology in the mouse. Cell 83 (1995) 473
47. Ozturk H., Gezici A., and Ozturk H. The effect of celecoxib, a selective COX-2 inhibitor, on liver ischemia/reperfusion-induced oxidative stress in rats. Hepatol Res 342 (2006) 76
48. Bordewick U., Heese M., Borchers T., et al. Compartmentation of hepatic fatty-acid-binding protein in liver cells and its effect on microsomal phosphatidic acid biosynthesis. Biol Chem Hoppe Seyler 370 (1989) 229
49. Fahimi H.D., Voelkl A., Vincent S.H., et al. Localization of the heme-binding protein in the cytoplasm and of a heme-binding protein-like immunoreactive protein in the nucleus of rat liver parenchymal cells: immunocytochemical evidence of the subcellular distribution corroborated by radioimmunoassay and immunoblotting. Hepatology 11 (1990) 859
50. Ek-Von Mentzer B.A., Zhang F., and Hamilton J.A. Binding of 13-hode and 15-hete to phospholipid bilayers, albumin, and intracellular fatty acid binding proteins, implications for transmembrane and intracellular transport and for protection from lipid peroxidation. J Biol Chem 276 (2001) 15575
51. Raza H., Pongubala J.R., and Sorof S. Specific high affinity binding of lipoxygenase metabolites of arachidonic acid by liver fatty acid binding protein. Biochem Biophys Res Commun 161 (1989) 448
52. Wang G., Gong Y., Anderson J., et al. Antioxidative function of L-FABP in L-FABP stably transfected Chang liver cells. Hepatology 424 (2005) 871
53. Cotgreave I.A. N-acetylcysteine: pharmacological considerations and experimental and clinical applications. Adv Pharmacol 38 (1997) 205
54. Fusai G., Glantzounis G.K., Hafez T., et al. N-Acetylcysteine ameliorates the late phase of liver ischaemia/reperfusion injury in the rabbit with hepatic steatosis. Clin Sci (Lond) 1095 (2005) 465
55. Amersi F., Nelson S.K., Shen X.D., et al. Bucillamine, a thiol antioxidant, prevents transplantation-associated reperfusion injury. Proc Natl Acad Sci 99 (2002) 8915
56. Dorman R.B., Bajt M.L., Farhood A., et al. Heme oxygenase-1 induction in hepatocytes and non-parenchymal cells protects against liver injury during endotoxemia. Comp Hepatol 3 suppl 1 (2004) S42
57. Maines M.D. The heme oxygenase system: a regulator of second messenger gases. Annu Rev Pharmacol Toxicol 37 (1997) 517
58. Fondevila C., Shen X.D., Tsuchiyashi S., et al. Biliverdin therapy protects rat livers from ischemia and reperfusion injury. Hepatology 406 (2004) 1333
59. Kato Y., Shimazu M., Kondo M., et al. Bilirubin rinse: A simple protectant against the rat liver graft injury mimicking heme oxygenase-1 preconditioning. Hepatology 382 (2003) 364
60. Lee W.Y., and Lee S.M. Ischemic preconditioning protects post-ischemic oxidative damage to mitochondria in rat liver. Shock 244 (2005) 370
61. Franco-Gou R., Rosello-Catafau J., Casillas-Ramirez A., et al. How ischaemic preconditioning protects small liver grafts. J Pathol 2081 (2006) 62
62. Hasegawa T., Malle E., Farhood A., et al. Generation of hypochlorite-modified proteins by neutrophils during ischemia-reperfusion injury in rat liver: attenuation by ischemic preconditioning. Am J Physiol Gastrointest Liver Physiol 2894 (2005) G760