An intervention study of the effects of calcium intake on faecal fat excretion, energy metabolism and adipose tissue mRNA expression of lipid-metabolism related proteins

International Journal of Obesity

Volumn 31, Issue 11, 2007, Pages 1704-1712

  Boon, N ^a   Hul, G B J ^a   Stegen, J H C H ^a   Sluijsmans, W E M ^a   Valle, C ^b,c   Langin, D ^b,c,d   Viguerie, N ^b,c   Saris, W H M ^a  

^a MAASTRICHT UNIVERSITY   (Netherlands)

^b INSERM   (France)

^c UNIVERSITÉ DE TOULOUSE   (France)

^d TOULOUSE UNIVERSITY HOSPITAL   (France)

Author keywords

Adipose tissue; Dietary calcium; Faecal fat excretion

Indexed keywords

CALCIUM CARBONATE; FATTY ACID SYNTHASE; FECES LIPID; MESSENGER RNA; TRIACYLGLYCEROL;

ADIPOSE TISSUE; ADULT; ARTICLE; BLOOD SAMPLING; BODY FAT; BODY MASS; CALCIUM EXCRETION; CALCIUM INTAKE; CONTROLLED STUDY; ENERGY EXPENDITURE; ENERGY METABOLISM; FECES; FEMALE; GENE EXPRESSION; HUMAN; HUMAN EXPERIMENT; LIPID METABOLISM; MALE; NORMAL HUMAN; OXIDATION; PRIORITY JOURNAL; STATISTICAL SIGNIFICANCE; TRIACYLGLYCEROL BLOOD LEVEL;

ADIPOCYTES; ADIPOSE TISSUE; ADULT; CALCIUM, DIETARY; CALORIMETRY, INDIRECT; CROSS-OVER STUDIES; DIET; ENERGY INTAKE; ENERGY METABOLISM; FATTY ACID SYNTHETASE COMPLEX; FECES; FEMALE; FOOD HABITS; GENE EXPRESSION REGULATION; HUMANS; LIPID METABOLISM; MALE; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; TRIGLYCERIDES;

EID: 35648933552     PISSN: 03070565     EISSN: 14765497     Source Type: Journal    
DOI: 10.1038/sj.ijo.0803660     Document Type: Article

References (40)

1. McCarron DA. Dietary calcium as an antihypertensive agent. Nutr Rev 1984; 42: 223-225.
2. Lin YC, Lyle RM, McCabe LD, McCabe GP, Weaver CM, Teegarden D. Dairy calcium is related to changes in body composition during a two-year exercise intervention in young women. J Am Coll Nutr 2000; 19: 754-760.
3. Shapses SA, Heshka S, Heymsfield SB. Effect of calcium supplementation on weight and fat loss in women. J Clin Endocrinol Metab 2004; 89: 632-637.
4. Pereira MA, Jacobs Jr DR, Van Horn L, Slattery ML, Kartashov AI, Ludwig DS. Dairy consumption, obesity, and the insulin resistance syndrome in young adults: the CARDIA Study. JAMA 2002; 287: 2081-2089.
5. Jacqmain M, Doucet E, Despres JP, Bouchard C, Tremblay A. Calcium intake, body composition, and lipoprotein-lipid concentrations in adults. Am J Clin Nutr 2003; 77: 1448-1452.
6. Davies KM, Heaney RP, Recker RR, Lappe JM, Barger-Lux MJ, Rafferty K et al. Calcium intake and body weight. J Clin Endocrinol Metab 2000; 85: 4635-4638.
7. Atkin LM, Davies PS. Diet composition and body composition in preschool children. Am J Clin Nutr 2000; 72: 15-21.
8. Zemel MB. Role of calcium and dairy products in energy partitioning and weight management. Am J Clin Nutr 2004; 79: 907S-912S.
9. Xue B, Moustaid N, Wilkison WO, Zemel MB. The agouti gene product inhibits lipolysis in human adipocytes via a Ca2+-dependent mechanism. FASEB J 1998; 12: 1391-1396.
10. Sun X, Zemel MB. Calcium and dairy products inhibit weight and fat regain during ad libitum consumption following energy restriction in Ap2-agouti transgenic mice. J Nutr 2004; 134: 3054-3060.
11. Zemel MB. Nutritional and endocrine modulation of intracellular calcium: implications in obesity, insulin resistance and hypertension. Mol Cell Biochem 1998; 188: 129-136.
12. Zemel MB. Effects of calcium-fortified breakfast cereal on adiposity in a transgenic mouse model of obesity. FASEB J 2001; 598 (abstract).
13. Shi H, Dirienzo D, Zemel MB. Effects of dietary calcium on adipocyte lipid metabolism and body weight regulation in energy-restricted aP2-agouti transgenic mice. FASEB J 2001; 15: 291-293.
14. Bowen J, Noakes M, Clifton PM. Effect of calcium and dairy foods in high protein, energy-restricted diets on weight loss and metabolic parameters in overweight adults. Int J Obes (Lond) 2005; 29: 957-965.
15. Thompson WG, Rostad Holdman N, Janzow DJ, Slezak JM, Morris KL, Zemel MB. Effect of energy-reduced diets high in dairy products and fiber on weight loss in obese adults. Obes Res 2005; 13: 1344-1353.
16. Zemel MB, Richards J, Mathis S, Milstead A, Gebhardt L, Silva E. Dairy augmentation of total and central fat loss in obese subjects. Int J Obes (Lond) 2005; 29: 391-397.
17. Bowen J, Noakes M, Clifton PM. Effect of calcium and dairy foods in high protein, energy-restricted diets on weight loss and metabolic parameters in overweight adults. Int J Obes Relat Metab Disord 2005.
18. Boon N, Hul GB, Viguerie N, Sicard A, Langin D, Saris WH. Effects of 3 diets with various calcium contents on 24-h energy expenditure, fat oxidation, and adipose tissue message RNA expression of lipid metabolism-related proteins. Am J Clin Nutr 2005; 82: 1244-1252.
19. Jacobsen R, Lorenzen JK, Toubro S, Krog-Mikkelsen I, Astrup A. Effect of short-term high dietary calcium intake on 24-h energy expenditure, fat oxidation, and fecal fat excretion. Int J Obes Relat Metab Disord 2005; 29: 292-301.
20. Shahkhalili Y, Murset C, Meirim I, Duruz E, Guinchard S, Cavadini C et al. Calcium supplementation of chocolate: effect on cocoa butter digestibility and blood lipids in humans. Am J Clin Nutr 2001; 73: 246-252.
21. Welberg JW, Monkelbaan JF, de Vries EG, Muskiet FA, Cats A, Oremus ET et al. Effects of supplemental dietary calcium on quantitative and qualitative fecal fat excretion in man. Ann Nutr Metab 1994; 38: 185-191.
22. Boon N, Hul GB, Sicard A, Kole E, Van Den Berg ER, Viguerie N et al. The effects of increasing serum calcitriol on energy and fat metabolism and gene expression. Obesity (Silver Spring) 2006; 14: 1739-1746.
23. Adriaens MP, Schoffelen PF, Westerterp KR. Intra-individual variation of basal metabolic rate and the influence of daily habitual physical activity before testing. Br J Nutr 2003; 90: 419-423.
24. Schoffelen PF, Westerterp KR, Saris WH, Ten Hoor F. A dual-respiration chamber system with automated calibration. J Appl Physiol 1997; 83: 2064-2072.
25. Weir J. New methods for calculating metabolic rate with special reference to protein metabolism. J Physiol 1949; 109: 101-109.
26. Peronnet F, Massicotte D. Table of nonprotein respiratory quotient: an update. Can J Sport Sci 1991; 16: 23-29.
27. Bligh EG, Dyer WJ. A rapid method of total lipid extraction and purification. Can J Med Sci 1959; 37: 911-917.
28. NEVO Table. Voorlichtingsbureau voor de voeding (Netherlands Nutrition Centre). Stichting Nederlands Voedingsstoffenbestand (Netherlands Food Composition Chart): Den Haag, 1996.
29. Harris. A biometric study of basal metabolism in man. Carnegie Institution of Washington: Washington, 1919.
30. Kerstetter JE, O'Brien KO, Insogna KL. Dietary protein affects intestinal calcium absorption. Am J Clin Nutr 1998; 68: 859-865.
31. Kerstetter JE, O'Brien KO, Insogna KL. Dietary protein, calcium metabolism, and skeletal homeostasis revisited. Am J Clin Nutr 2003; 78: 584S-592S.
32. Kerstetter JE, O'Brien KO, Insogna KL. Low protein intake: the impact on calcium and bone homeostasis in humans. J Nutr 2003; 133: 855S-861S.
33. Kerstetter JE, Svastisalee CM, Caseria DM, Mitnick ME, Insogna KL. A threshold for low-protein-diet-induced elevations in parathyroid hormone. Am J Clin Nutr 2000; 72: 168-173.
34. Govers MJ, Termont DS, Lapre JA, Kleibeuker JH, Vonk RJ, Van der Meer R. Calcium in milk products precipitates intestinal fatty acids and secondary bile acids and thus inhibits colonic cytotoxicity in humans. Cancer Res 1996; 56: 3270-3275.
35. Cummings NK, Soares MJ, James AP, Ping-Delfos WC. Comparison of dairy and non-dairy sources of calcium on thermogenesis and substrate oxidation in humans. Asia Pac J Clin Nutr 2004; 13: S87.
36. Melanson EL, Donahoo WT, Dong F, Ida T, Zemel MB. Effect of low- and high-calcium dairy-based diets on macronutrient oxidation in humans. Obes Res 2005; 13: 2102-2112.
37. Melanson EL, Sharp TA, Schneider J, Donahoo WT, Grunwald GK, Hill JO. Relation between calcium intake and fat oxidation in adult humans. Int J Obes Relat Metab Disord 2003; 27: 196-203.
38. Boon N, Hul GB, Sicard A, Kole E, Van Den Berg ER, Viguerie N et al. The effects of increasing serum calcitriol on energy and fat metabolism and gene expression. Obesity (Silver Spring) 2006; 14: 1739-1746.
39. Zemel MB, Shi H, Greer B, Dirienzo D, Zemel PC. Regulation of adiposity by dietary calcium. FASEB J 2000; 14: 1132-1138.
40. Shi H, Halvorsen YD, Ellis PN, Wilkison WO, Zemel MB. Role of intracellular calcium in human adipocyte differentiation. Physiol Genomics 2000; 3: 75-82.