Functional role of transmembrane helix 6 in drug binding and transport by the ABC transporter MsbA

Biochemistry

Volumn 47, Issue 41, 2008, Pages 10904-10914

  Woebking, Barbara ^a   Velamakanni, Saroj ^a   Federici, Luca ^b   Seeger, Markus A ^a   Murakami, Satoshi ^c   Van Veen, Hendrik W ^a  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^b UNIVERSITY OF CHIETI   (Italy)

^c TOKYO INSTITUTE OF TECHNOLOGY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIA; CELL MEMBRANES; CRYSTAL STRUCTURE; DRUG INTERACTIONS; ESCHERICHIA COLI; FLOW INTERACTIONS; MONOMERS; SUBSTRATES;

ABC TRANSPORTERS; ATP-BINDING CASSETTE; BINDING SURFACES; COLOCALIZE; DRUG BINDING; ETHIDIUM; GRAM-NEGATIVE BACTERIA; HOECHST; HOT SPOTTING; PERIPLASM; PERIPLASMIC; PROTEIN INTERACTIONS; SALMONELLA TYPHIMURIUM; SUBSTRATE SPECIFICITY; TOXIC IONS; TRANSMEMBRANE HELICES;

ANIMAL CELL CULTURE;

ABC TRANSPORTER; ETHIDIUM; HOE 33342; MSBA PROTEIN; PACLITAXEL;

AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; ARTICLE; CRYSTAL STRUCTURE; DRUG PROTEIN BINDING; DRUG TRANSPORT; ESCHERICHIA COLI; MOLECULAR INTERACTION; NONHUMAN; PRIORITY JOURNAL; SALMONELLA TYPHIMURIUM; SURFACE PROPERTY;

ADENOSINE TRIPHOSPHATASES; ATP-BINDING CASSETTE TRANSPORTERS; BACTERIAL PROTEINS; BASE SEQUENCE; DNA PRIMERS; FLUORESCENCE POLARIZATION; MUTAGENESIS, SITE-DIRECTED; PHARMACEUTICAL PREPARATIONS;

ESCHERICHIA COLI; NEGIBACTERIA; SALMONELLA TYPHIMURIUM;

EID: 53749101652     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi800778d     Document Type: Article

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