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Volumn 151, Issue 1, 2008, Pages 21-28
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Highly efficient regioselective synthesis of 5-O-lauroyl-5-azacytidine catalyzed by Candida antarctica lipase B
a
a
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Author keywords
5 Azacytidine; Novozym 435; Organic solvent; Regioselective acylation; Vinyl laurate
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Indexed keywords
5-AZACYTIDINE;
CANDIDA ANTARCTICA;
CANDIDA ANTARCTICA LIPASE B;
ENZYMATIC ACYLATION;
HYDROXYL GROUPS;
IMMOBILIZED LIPASE;
KEY VARIABLES;
MOLAR RATIOS;
NOVOZYM 435;
OPTIMIZED CONDITIONS;
REACTION MEDIUMS;
REACTION TEMPERATURES;
REACTION TIME;
REGIOSELECTIVE ACYLATION;
REGIOSELECTIVE SYNTHESIS;
SUBSTRATE CONVERSIONS;
VINYL LAURATE;
WATER ACTIVITIES;
ISOMERS;
ORGANIC SOLVENTS;
REACTION RATES;
REGIOSELECTIVITY;
ACYLATION;
5' O LAUROYL 5 AZACYTIDINE;
AZACITIDINE;
LAURIC ACID;
LIPASE B;
PYRIDINE;
UNCLASSIFIED DRUG;
IMMOBILIZED ENZYME;
LAURIC ACID DERIVATIVE;
LIPASE B, CANDIDA ANTARCTICA;
NOVOZYME 435;
TRIACYLGLYCEROL LIPASE;
ARTICLE;
CANDIDA ANTARCTICA;
CATALYSIS;
DRUG STRUCTURE;
DRUG SYNTHESIS;
ENZYME MECHANISM;
NONHUMAN;
CHEMISTRY;
ISOMERISM;
SYNTHESIS;
CANDIDA ANTARCTICA;
AZACITIDINE;
CATALYSIS;
ENZYMES, IMMOBILIZED;
ISOMERISM;
LAURATES;
LIPASE;
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EID: 53749095260
PISSN: 02732289
EISSN: None
Source Type: Journal
DOI: 10.1007/s12010-008-8152-0 Document Type: Article |
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Times cited : (7)
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References (34)
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