Electrochemical behaviour and micromolar determination of the antineoplastic agent 5-azacytidine and its mixtures with the nucleoside cytidine

Journal of Electroanalytical Chemistry

Volumn 407, Issue 1-2, 1996, Pages 189-194

  Marin D ^a   Teijeiro, C ^a   Pina J J ^a  

^a UNIVERSITY OF ALCALÁ   (Spain)

Author keywords

5 Azacytidine; Antimetabolites; Differential pulse polarography; Electrochemistry; Reduction mechanism

Indexed keywords

AGENTS; COMPOSITION EFFECTS; DRUG THERAPY; ORGANIC COMPOUNDS; POLAROGRAPHIC ANALYSIS; REDOX REACTIONS;

ANTIMETABOLITES; ANTINEOPLASTIC AGENTS; DIFFERENTIAL PULSE POLAROGRAPHY; NUCLEOSIDE CYTIDINE;

ELECTROCHEMISTRY;

EID: 0030144370     PISSN: 15726657     EISSN: None     Source Type: Journal    
DOI: 10.1016/0022-0728(95)04471-X     Document Type: Article

References (30)

1. W.A. Remers, in R.F. Doerge (Ed.), Wilson and Gisvold's Textbook of Organic Medical and Pharmaceutical Chemistry, J.B. Lippincott, Philadelphia, 1982, p. 295.
2. M. MacCoss and M.J. Robins, in D.E.V. Witman (Ed.), The Chemistry of Antitumor Agents, Blackie, Glasgow, 1990, p. 261.
3. A.B. Glover, B.R. Leyland-Jones, H.G. Chun, B. Davies and D.F. Hoth, Cancer Treat. Rep., 71 (1987) 737.
4. A.B. Glover and B. Leyland-Jones, Cancer Treat. Rep., 71 (1987) 959.
5. L. Radnedge and R.J. Pinney, J. Pharm. Pharmacol., 44 (1992) 266.
6. P.M. Bersier and J. Bersier, in G. Svehla et al. (Eds.), Comprehensive Analytical Chemistry, Vol. 27: Analytical Voltammetry, Elsevier, Amsterdam, 1992, p. 159.
7. C. Teijeiro and D. Marín, J. Electroanal. Chem., 316 (1991) 119.
8. D. Marín and C. Teijeiro, Bioelectrochem. Bioenerg., 34 (1994) 25.
9. C. Teijeiro and D. Marín, J. Electroanal. Chem., 337 (1992) 175.
10. D. Marín and C. Teijeiro, Bioelectrochem. Bioenerg., 34 (1994) 25.
11. L. Kittler and H. Berg, J. Electroanal. Chem., 16 (1968) 251.
12. R.E. Notari and J.L. DeYoung, J. Pharm. Sci., 64 (1975) 1148.
13. K.K. Chan, D.D. Giannini, J.A. Staroscik and W. Sadee, J. Pharm. Sci., 68 (1979) 807.
14. Y.W. Cheung, B.R. Vishnuvajjala, N.L. Morris and K.P. Flora, Am. J. Hosp. Pharm., 41 (1984) 1156.
15. L.H. Li, H.H. Buskirk, C.L. Blowers, G.L. Neil and L.J. Hanka, J. Antibiotic., 37 (1984) 419.
16. A. Vachálková, L. Novotny and A. Pískala, Neoplasma, 40 (1993) 289.
17. L. Novotny, A. Vacháldová and A. Pískala, Collect. Czech. Chem. Commun., 59 (1994) 1691.
18. L.D. Kissinger and N.L. Stemm, J. Chromatogr., 353 (1986) 309.
19. A.M. Rustum and N.El. Hoffman, J. Chromatogr., 421 (1987) 387.
20. S.V. Galushko, I.P. Shishkina and A.T. Pilipenko, J. Chromatogr., 445 (1988) 59.
21. A.M. Ghe, G. Chiavari and J. Evgenidis, Talanta, 33 (1986) 379.
22. D. Gningue and J.J. Aaron, Talanta, 32 (1985) 183.
23. W.P. van Bennekon̄m and V.R. Tjaden, Anal. Chim. Acta, 156 (1984) 289.
24. T.E. Cummings, J.R. Fraser and P.J. Elving, Anal. Chem., 52 (1980) 558.
25. Y.M. Temerk, M.M. Kamal, M.E. Ahmed and M. Ibrahim, J. Electroanal. Chem., 156 (1983) 449.
26. E. Palecek, F. Jelen, M.A. Hung and J. Lasovsky, Bioelectrochem. Bioenerg., 8 (1981) 621.
27. J.D. Roberts, G.R. Sullivan, P.P. Pang and N.J. Leonard, J. Org. Chem., 46 (1981) 1015.
28. A.M. Bond, Modern Polarographic Methods in Analytical Chemistry, Marcel Dekker, New York, 1980, p. 195.
29. J.A. Beisler, M.M. Abbasi and J.S. Driscoll, Cancer Treat. Rep., 60 (1976) 1671.
30. J.A. Beisler, M.M. Abbasi, J.A. Kelley and J.S. Driscoll, J. Med. Chem., 20 (1977) 806.