Scrapie-induced defects in learning and memory of transgenic mice expressing anchorless prion protein are associated with alterations in the gamma aminobutyric acid-ergic pathway

Journal of Virology

Volumn 82, Issue 20, 2008, Pages 9890-9899

  Trifilo, Matthew J ^a   Sanchez Alavez, Manuel ^a   Solforosi, Laura ^a   Bernard Trifilo, Joie ^a   Kunz, Stefan ^a   McGavern, Dorian ^a   Oldstone, Michael B A ^a  

^a SCRIPPS RESEARCH INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

4 AMINOBUTYRIC ACID; 4 AMINOBUTYRIC ACID A RECEPTOR; GLUTAMIC ACID; GLYCOSYLPHOSPHATIDYLINOSITOL ANCHORED PROTEIN; MONOCLONAL ANTIBODY; N METHYL DEXTRO ASPARTIC ACID; PRION PROTEIN; GLYCOSYLPHOSPHATIDYLINOSITOL;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CENTRAL NERVOUS SYSTEM; CEREBELLUM DEGENERATION; CONTROLLED STUDY; DISEASE ASSOCIATION; DISEASE EXACERBATION; EXTRAPYRAMIDAL SYNDROME; GABAERGIC SYSTEM; LEARNING DISORDER; LONG TERM POTENTIATION; MEMORY DISORDER; MOUSE; NERVE CELL NECROSIS; NERVE EXCITABILITY; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FOLDING; PROTEIN LOCALIZATION; SCRAPIE; SCRAPIE AGENT; TRANSGENIC MOUSE; ANIMAL; ANIMAL BEHAVIOR; BRAIN; C57BL MOUSE; ELECTROPHYSIOLOGY; GENETICS; HISTOLOGY; HUMAN; METABOLISM; MOUSE MUTANT; NEUROPSYCHOLOGICAL TEST; PATHOLOGY; PATHOPHYSIOLOGY; PHYSIOLOGY; PRION; RANDOMIZATION;

MURINAE; MUS; MUS MUSCULUS;

ANIMALS; BEHAVIOR, ANIMAL; BRAIN; ELECTROPHYSIOLOGY; GAMMA-AMINOBUTYRIC ACID; GLYCOSYLPHOSPHATIDYLINOSITOLS; HUMANS; LEARNING DISORDERS; MEMORY DISORDERS; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MICE, TRANSGENIC; NEUROPSYCHOLOGICAL TESTS; PRIONS; RANDOM ALLOCATION; RECEPTORS, GABA-A; SCRAPIE;

EID: 53749094052     PISSN: 0022538X     EISSN: None     Source Type: Journal    
DOI: 10.1128/JVI.00486-08     Document Type: Article

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