Prion protein is necessary for latent learning and long-term memory retention

Cellular and Molecular Neurobiology

Volumn 17, Issue 5, 1997, Pages 537-545

  Nishida, Noriyuki ^a   Katamine, Shigeru ^a   Shigematsu, Kazuto ^b   Nakatani, Akira ^a   Sakamoto, Nobuhiro ^a   Hasegawa, Sumitaka ^a   Nakaoke, Ryota ^a   Atarashi, Ryuichiro ^a   Kataoka, Yasufumi ^c   Miyamoto, Tsutomu ^a  

^a NAGASAKI UNIVERSITY   (Japan)

^b NAGASAKI UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^c Department of Hospital PharmacyKyushu University Faculty of MedicineHigashi ku ^*  (Japan)

Author keywords

Latent learning; Long term memory; Prion protein; PrP gene knockout mice

Indexed keywords

PRION PROTEIN;

ANIMAL MODEL; ARTICLE; BRAIN WEIGHT; CENTRAL NERVOUS SYSTEM DISEASE; LEARNING; LONG TERM MEMORY; MEMORY CONSOLIDATION; MOUSE; NONHUMAN; PATHOGENESIS; PRION DISEASE; PRIORITY JOURNAL; TASK PERFORMANCE;

EID: 0030868399     PISSN: 02724340     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1026315006619     Document Type: Article

References (6)

1. Abraham, W. C., Mason, S. E., Demmer, J., Williams, J. M., Richardson, C. L., Tate, W. P., Lowlor, P. A., and Dragunow, M. (1993). Correlations between immediate early gene induction and the persistence of long-term potentiation. Neuroscience 56:717-727.
2. Askanas, V., Bilak, M., Engel, W. K., Leclerc, A., and Tom, F. (1993). Prion protein is strongly immunolocalized at the postsynaptic domain of human normal neuromuscular junctions. Neurosci. Lett. 159:111-114.
3. Borchelt, D. R., Koliatsos, V. E., Guarnieri, M., Pardo, C. A., Sisodia, S. S., and Price, D. L. (1994). Rapid anterograde axonal transport of the cellular prion glycoprotein in the peripheral and central nervous systems. J. Biol. Chem. 269:14711-14717.
4. Bourtchuladze, R., Frenguelli, B., Blendy, J., Cioffi, D., Schutz, G., and Silva, A. J. (1994). Deficient long-term memory in mice with a targeted mutation of the cAMP-responsive element-binding protein. Cell 79:59-68.
5. Büeller, H., Fischer, M., Lang, Y., Bluethmann, H., Lipp, H.-P., DeArmond, S. J., Prusiner, S. B., Aguet, M., and Weissmann, C. (1992). Normal development and behavior of mice lacking the neuronal cell-surface PrP protein. Nature 356:577-582.
6. + currents. Neurosci. Lett. 209:49-52.