메뉴 건너뛰기




Volumn 12, Issue 4, 2008, Pages 209-218

Recognition of genetic factors influencing the progression of hepatitis C: Potential for personalized therapy

Author keywords

Biomarkers; Genetic polymorphism; Hepatic fibrosis; Hepatitis C

Indexed keywords

ANGIOTENSIN; ANTIFIBROTIC AGENT; CHEMOKINE RECEPTOR CCR5; HFE PROTEIN; INTERLEUKIN 10; MICROSOMAL TRIGLYCERIDE TRANSFER PROTEIN; MONOCYTE CHEMOTACTIC PROTEIN 1; PEGINTERFERON; RIBAVIRIN; TRANSFORMING GROWTH FACTOR BETA1; TRIACYLGLYCEROL; TUMOR NECROSIS FACTOR ALPHA;

EID: 53749084231     PISSN: 11771062     EISSN: None     Source Type: Journal    
DOI: 10.1007/BF03256286     Document Type: Review
Times cited : (14)

References (113)
  • 1
    • 85036895422 scopus 로고    scopus 로고
    • online, Available from URL:, Accessed 2008 Jul 4
    • WHO. Hepatitis C [online]. Available from URL: http://www.who.int/csr/ disease/hepatitis/whocdscsrlyo2003/en/index3.html#prevalence [Accessed 2008 Jul 4]
    • , vol.100
  • 2
    • 0033406372 scopus 로고    scopus 로고
    • Hepatitis C: The clinical spectrum of the disease
    • Marcellin P. Hepatitis C: the clinical spectrum of the disease. J Hepatol 1999; 31: 9-16
    • (1999) J Hepatol , vol.31 , pp. 9-16
    • Marcellin, P.1
  • 3
    • 0036828784 scopus 로고    scopus 로고
    • The burden of hepatitis C in the United States
    • Nov;
    • Kim WR. The burden of hepatitis C in the United States. Hepatology 2002 Nov; 36 (5): S30-4
    • (2002) Hepatology , vol.36 , Issue.5
    • Kim, W.R.1
  • 4
    • 0037378713 scopus 로고    scopus 로고
    • Measurement and determinants of the natural history of liver fibrosis in hepatitis C virus infection: A cross sectional and longitudinal study
    • Apr;
    • Wright M, Goldin R, Fabre A, et al. Measurement and determinants of the natural history of liver fibrosis in hepatitis C virus infection: a cross sectional and longitudinal study. Gut 2003 Apr; 52 (4): 574-9
    • (2003) Gut , vol.52 , Issue.4 , pp. 574-579
    • Wright, M.1    Goldin, R.2    Fabre, A.3
  • 5
    • 0024509701 scopus 로고
    • Isolation of a cDNA clone derived from a blood-borne non-A, non-B viral-hepatitis genome
    • Apr;
    • Choo QL, Kuo G, Weiner AJ, et al. Isolation of a cDNA clone derived from a blood-borne non-A, non-B viral-hepatitis genome. Science 1989 Apr; 244 (4902): 359-62
    • (1989) Science , vol.244 , Issue.4902 , pp. 359-362
    • Choo, Q.L.1    Kuo, G.2    Weiner, A.J.3
  • 6
    • 1442281992 scopus 로고    scopus 로고
    • Structural biology of hepatitis C virus
    • Jan;
    • Penin F, Dubuisson J, Rey FA, et al. Structural biology of hepatitis C virus. Hepatology 2004 Jan; 39 (1): 5-19
    • (2004) Hepatology , vol.39 , Issue.1 , pp. 5-19
    • Penin, F.1    Dubuisson, J.2    Rey, F.A.3
  • 7
    • 25844523297 scopus 로고    scopus 로고
    • Consensus proposals for a unified system of nomenclature of hepatitis C virus genotypes
    • Oct;
    • Simmonds P, Bukh J, Combet C, et al. Consensus proposals for a unified system of nomenclature of hepatitis C virus genotypes. Hepatology 2005 Oct; 42 (4): 962-73
    • (2005) Hepatology , vol.42 , Issue.4 , pp. 962-973
    • Simmonds, P.1    Bukh, J.2    Combet, C.3
  • 8
    • 32344431567 scopus 로고    scopus 로고
    • Chronic hepatitis C virus management: 2000-2005 update
    • Jan;
    • Hughes CA, Shafran SD. Chronic hepatitis C virus management: 2000-2005 update. Ann Pharmacother 2006 Jan; 40 (1): 74-82
    • (2006) Ann Pharmacother , vol.40 , Issue.1 , pp. 74-82
    • Hughes, C.A.1    Shafran, S.D.2
  • 9
    • 0036830454 scopus 로고    scopus 로고
    • Side effects of therapy of hepatitis C and their management
    • Nov;
    • Fried MW. Side effects of therapy of hepatitis C and their management. Hepatology 2002 Nov; 36 (5): S237-44
    • (2002) Hepatology , vol.36 , Issue.5
    • Fried, M.W.1
  • 10
    • 0037517079 scopus 로고    scopus 로고
    • Side effects of therapy for chronic hepatitis C
    • May;
    • Russo MW, Fried MW. Side effects of therapy for chronic hepatitis C. Gastroenterology 2003 May; 124 (6): 1711-9
    • (2003) Gastroenterology , vol.124 , Issue.6 , pp. 1711-1719
    • Russo, M.W.1    Fried, M.W.2
  • 11
    • 35648940270 scopus 로고    scopus 로고
    • Interferon alpha treatment and thyroid dysfunction
    • Dec;
    • Tomer Y, Blackard JT, Akeno N. Interferon alpha treatment and thyroid dysfunction. Endocrinol Metab Clin North Am 2007 Dec; 36 (4): 1051-61
    • (2007) Endocrinol Metab Clin North Am , vol.36 , Issue.4 , pp. 1051-1061
    • Tomer, Y.1    Blackard, J.T.2    Akeno, N.3
  • 12
    • 0035934568 scopus 로고    scopus 로고
    • Peginterferon alfa-2b plus ribavirin compared with interferon alfa-2b plus ribavirin for initial treatment of chronic hepatitis C: A randomised trial
    • Sep;
    • Manns MP, McHutchison JG, Gordon SC, et al. Peginterferon alfa-2b plus ribavirin compared with interferon alfa-2b plus ribavirin for initial treatment of chronic hepatitis C: a randomised trial. Lancet 2001 Sep; 358 (9286): 958-65
    • (2001) Lancet , vol.358 , Issue.9286 , pp. 958-965
    • Manns, M.P.1    McHutchison, J.G.2    Gordon, S.C.3
  • 13
    • 0037179698 scopus 로고    scopus 로고
    • Peginterferon alfa-2a plus ribavirin for chronic hepatitis C virus infection
    • Sep;
    • Fried MW, Shiffman ML, Reddy KR, et al. Peginterferon alfa-2a plus ribavirin for chronic hepatitis C virus infection. N Engl J Med 2002 Sep; 347 (13): 975-82
    • (2002) N Engl J Med , vol.347 , Issue.13 , pp. 975-982
    • Fried, M.W.1    Shiffman, M.L.2    Reddy, K.R.3
  • 14
    • 0043037223 scopus 로고    scopus 로고
    • High body mass index is an independent risk factor for nonresponse to antiviral treatment in chronic hepatitis C
    • Sep;
    • Bressler BL, Guindi M, Tomlinson G, et al. High body mass index is an independent risk factor for nonresponse to antiviral treatment in chronic hepatitis C. Hepatology 2003 Sep; 38 (3): 639-44
    • (2003) Hepatology , vol.38 , Issue.3 , pp. 639-644
    • Bressler, B.L.1    Guindi, M.2    Tomlinson, G.3
  • 15
    • 33645124902 scopus 로고    scopus 로고
    • Management of patients with chronic hepatitis C infection
    • Mar;
    • Herrine SK, Rossi S, Navarro VJ. Management of patients with chronic hepatitis C infection. Clin Exper Med 2006 Mar; 6 (1): 20-6
    • (2006) Clin Exper Med , vol.6 , Issue.1 , pp. 20-26
    • Herrine, S.K.1    Rossi, S.2    Navarro, V.J.3
  • 16
    • 30044432484 scopus 로고    scopus 로고
    • American Gastroenterological Association technical review on the management of hepatitis C
    • Jan;
    • Dienstag JL, McHutchison JG. American Gastroenterological Association technical review on the management of hepatitis C. Gastroenterology 2006 Jan; 130 (1): 231-64
    • (2006) Gastroenterology , vol.130 , Issue.1 , pp. 231-264
    • Dienstag, J.L.1    McHutchison, J.G.2
  • 17
    • 3242759735 scopus 로고    scopus 로고
    • Host genetic determinants in hepatitis C virus infection
    • Jun;
    • Yee LJ. Host genetic determinants in hepatitis C virus infection. Genes Immun 2004 Jun; 5 (4): 237-45
    • (2004) Genes Immun , vol.5 , Issue.4 , pp. 237-245
    • Yee, L.J.1
  • 18
    • 0037220482 scopus 로고    scopus 로고
    • Liver fibrosis: From bench to bedside
    • Friedman SL. Liver fibrosis: from bench to bedside. J Hepatol 2003; 38 Suppl. 1: S38-53
    • (2003) J Hepatol , vol.38 , Issue.SUPPL. 1
    • Friedman, S.L.1
  • 19
    • 34548277150 scopus 로고    scopus 로고
    • Grading and staging systems for inflammation and fibrosis in chronic liver diseases
    • Oct;
    • Goodman ZD. Grading and staging systems for inflammation and fibrosis in chronic liver diseases. J Hepatol 2007 Oct; 47 (4): 598-607
    • (2007) J Hepatol , vol.47 , Issue.4 , pp. 598-607
    • Goodman, Z.D.1
  • 20
    • 14644390213 scopus 로고    scopus 로고
    • The liver biopsy in chronic hepatitis C: A view from the other side of the microscope
    • Feb;
    • Kleiner DE. The liver biopsy in chronic hepatitis C: a view from the other side of the microscope. Semin Liver Dis 2005 Feb; 25 (1): 52-64
    • (2005) Semin Liver Dis , vol.25 , Issue.1 , pp. 52-64
    • Kleiner, D.E.1
  • 21
    • 0030933395 scopus 로고    scopus 로고
    • Natural history of liver fibrosis progression in patients with chronic hepatitis C
    • Mar;
    • Poynard T, Bedossa P, Opolon P. Natural history of liver fibrosis progression in patients with chronic hepatitis C. Lancet 1997 Mar; 349 (9055): 825-32
    • (1997) Lancet , vol.349 , Issue.9055 , pp. 825-832
    • Poynard, T.1    Bedossa, P.2    Opolon, P.3
  • 22
    • 0035009810 scopus 로고    scopus 로고
    • Rates and risk factors of liver fibrosis progression in patients with chronic hepatitis C
    • May;
    • Poynard T, Ratziu V, Charlotte F, et al. Rates and risk factors of liver fibrosis progression in patients with chronic hepatitis C. J Hepatol 2001 May; 34 (5): 730-9
    • (2001) J Hepatol , vol.34 , Issue.5 , pp. 730-739
    • Poynard, T.1    Ratziu, V.2    Charlotte, F.3
  • 23
    • 0030800166 scopus 로고    scopus 로고
    • Epidemiological factors affecting the severity of hepatitis C virus-related liver disease: A French survey of 6,664 patients
    • Aug;
    • Roudot-Thoraval F, Bastie A, Pawlotsky JM, et al. Epidemiological factors affecting the severity of hepatitis C virus-related liver disease: a French survey of 6,664 patients. Hepatology 1997 Aug; 26 (2): 485-90
    • (1997) Hepatology , vol.26 , Issue.2 , pp. 485-490
    • Roudot-Thoraval, F.1    Bastie, A.2    Pawlotsky, J.M.3
  • 24
    • 0031767537 scopus 로고    scopus 로고
    • Coinfection by hepatitis B virus and hepatitis C virus
    • Pontisso P, Gerotto M, Benvegnu L, et al. Coinfection by hepatitis B virus and hepatitis C virus. Antiviral Ther 1998; 3: 137-42
    • (1998) Antiviral Ther , vol.3 , pp. 137-142
    • Pontisso, P.1    Gerotto, M.2    Benvegnu, L.3
  • 25
    • 0029962815 scopus 로고    scopus 로고
    • Independent and additive effect modification of hepatitis C and B viruses infection on the development of chronic hepatitis
    • Mar;
    • Tsai JF, Jeng JE, Ho MS, et al. Independent and additive effect modification of hepatitis C and B viruses infection on the development of chronic hepatitis. J Hepatol 1996 Mar; 24 (3): 271-6
    • (1996) J Hepatol , vol.24 , Issue.3 , pp. 271-276
    • Tsai, J.F.1    Jeng, J.E.2    Ho, M.S.3
  • 26
    • 0032124862 scopus 로고    scopus 로고
    • Predictive factors for development of cirrhosis in parenterally acquired chronic hepatitis C: A comparison between immunocompetent and immunocompromised patients
    • Jul;
    • Pol S, Fontaine H, Carnot F, et al. Predictive factors for development of cirrhosis in parenterally acquired chronic hepatitis C: a comparison between immunocompetent and immunocompromised patients. J Hepatol 1998 Jul; 29 (1): 12-9
    • (1998) J Hepatol , vol.29 , Issue.1 , pp. 12-19
    • Pol, S.1    Fontaine, H.2    Carnot, F.3
  • 27
    • 0034070192 scopus 로고    scopus 로고
    • HCV-related fibrosis progression following liver transplantation: Increase in recent years
    • Apr;
    • Berenguer M, Ferrell L, Watson J, et al. HCV-related fibrosis progression following liver transplantation: increase in recent years. J Hepatol 2000 Apr; 32 (4): 673-84
    • (2000) J Hepatol , vol.32 , Issue.4 , pp. 673-684
    • Berenguer, M.1    Ferrell, L.2    Watson, J.3
  • 28
    • 0024311206 scopus 로고
    • Rapidly progressive non-A, non-B-hepatitis in patients with human immunodeficiency virus infection
    • Dec;
    • Martin P, Dibisceglie AM, Kassianides C, et al. Rapidly progressive non-A, non-B-hepatitis in patients with human immunodeficiency virus infection. Gastroenterology 1989 Dec; 97 (6): 1559-61
    • (1989) Gastroenterology , vol.97 , Issue.6 , pp. 1559-1561
    • Martin, P.1    Dibisceglie, A.M.2    Kassianides, C.3
  • 29
    • 0342601406 scopus 로고    scopus 로고
    • Human immunodeficiency virus infection modifies the natural history of chronic parenterally-acquired hepatitis C with an unusually rapid progression to cirrhosis
    • Jan;
    • Soto B, SanchezQuijano A, Rodrigo L, et al. Human immunodeficiency virus infection modifies the natural history of chronic parenterally-acquired hepatitis C with an unusually rapid progression to cirrhosis. J Hepatol 1997 Jan; 26 (1): 1-5
    • (1997) J Hepatol , vol.26 , Issue.1 , pp. 1-5
    • Soto, B.1    SanchezQuijano, A.2    Rodrigo, L.3
  • 30
    • 0032924020 scopus 로고    scopus 로고
    • Fibrosis in chronic hepatitis C correlates significantly with body mass index and steatosis
    • Apr;
    • Hourigan LF, Macdonald GA, Purdie D, et al. Fibrosis in chronic hepatitis C correlates significantly with body mass index and steatosis. Hepatology 1999 Apr; 29 (4): 1215-9
    • (1999) Hepatology , vol.29 , Issue.4 , pp. 1215-1219
    • Hourigan, L.F.1    Macdonald, G.A.2    Purdie, D.3
  • 31
    • 0034987263 scopus 로고    scopus 로고
    • Steatosis accelerates the progression of liver damage of chronic hepatitis C patients and correlates with specific HCV genotype and visceral obesity
    • Jun;
    • Adinolfi LE, Gambardella M, Andreana A, et al. Steatosis accelerates the progression of liver damage of chronic hepatitis C patients and correlates with specific HCV genotype and visceral obesity. Hepatology 2001 Jun; 33 (6): 1358-64
    • (2001) Hepatology , vol.33 , Issue.6 , pp. 1358-1364
    • Adinolfi, L.E.1    Gambardella, M.2    Andreana, A.3
  • 32
    • 0346874154 scopus 로고    scopus 로고
    • In overweight patients with chronic hepatitis C, circulating insulin is associated with hepatic fibrosis: Implications for therapy
    • Dec;
    • Hickman IJ, Powell EE, Prins JB, et al. In overweight patients with chronic hepatitis C, circulating insulin is associated with hepatic fibrosis: implications for therapy. J Hepatol 2003 Dec; 39 (6): 1042-8
    • (2003) J Hepatol , vol.39 , Issue.6 , pp. 1042-1048
    • Hickman, I.J.1    Powell, E.E.2    Prins, J.B.3
  • 33
    • 21044456174 scopus 로고    scopus 로고
    • Insulin resistance is a cause of steatosis and fibrosis progression in chronic hepatitis C
    • Jul;
    • Fartoux L, Poujol-Robert A, Guechot J, et al. Insulin resistance is a cause of steatosis and fibrosis progression in chronic hepatitis C. Gut 2005 Jul; 54 (7): 1003-8
    • (2005) Gut , vol.54 , Issue.7 , pp. 1003-1008
    • Fartoux, L.1    Poujol-Robert, A.2    Guechot, J.3
  • 34
    • 0036829816 scopus 로고    scopus 로고
    • Natural history of chronic hepatitis C
    • Nov;
    • Seeff LB. Natural history of chronic hepatitis C. Hepatology 2002 Nov; 36 (5): S35-46
    • (2002) Hepatology , vol.36 , Issue.5
    • Seeff, L.B.1
  • 35
    • 30144431739 scopus 로고    scopus 로고
    • Natural history and predictors of disease severity in chronic hepatitis C
    • Massard J, Ratziu V, Thabut D, et al. Natural history and predictors of disease severity in chronic hepatitis C. J Hepatol 2006; 44: S19-24
    • (2006) J Hepatol , vol.44
    • Massard, J.1    Ratziu, V.2    Thabut, D.3
  • 36
    • 34347332337 scopus 로고    scopus 로고
    • Immunopathogenesis of hepatitis C infection and hepatic fibrosis: New insights into antifibrotic therapy in chronic hepatitis C
    • Aug;
    • Teixeira R, Marcos LA, Friedman SL. Immunopathogenesis of hepatitis C infection and hepatic fibrosis: new insights into antifibrotic therapy in chronic hepatitis C. Hepatol Res 2007 Aug; 37 (8): 579-95
    • (2007) Hepatol Res , vol.37 , Issue.8 , pp. 579-595
    • Teixeira, R.1    Marcos, L.A.2    Friedman, S.L.3
  • 37
  • 38
    • 42949163491 scopus 로고    scopus 로고
    • Mechanisms of hepatic fibrogenesis
    • May;
    • Friedman SL. Mechanisms of hepatic fibrogenesis. Gastroenterology 2008 May; 134 (6): 1655-69
    • (2008) Gastroenterology , vol.134 , Issue.6 , pp. 1655-1669
    • Friedman, S.L.1
  • 39
    • 0037371468 scopus 로고    scopus 로고
    • Genetic polymorphisms and the progression of liver fibrosis: A critical appraisal
    • Mar;
    • Bataller R, North KE, Brenner DA. Genetic polymorphisms and the progression of liver fibrosis: a critical appraisal. Hepatology 2003 Mar; 37 (3): 493-503
    • (2003) Hepatology , vol.37 , Issue.3 , pp. 493-503
    • Bataller, R.1    North, K.E.2    Brenner, D.A.3
  • 40
    • 33644509858 scopus 로고    scopus 로고
    • Hepatitis C: Identifying patients with progressive liver injury
    • Feb;
    • Feld JJ, Liang TJ. Hepatitis C: identifying patients with progressive liver injury. Hepatology 2006 Feb; 43 (2): S194-206
    • (2006) Hepatology , vol.43 , Issue.2
    • Feld, J.J.1    Liang, T.J.2
  • 41
    • 33847054368 scopus 로고    scopus 로고
    • Genetics, genomics, and proteomics: Implications for the diagnosis and the treatment of chronic hepatitis C
    • Feb;
    • Asselah T, Bieche I, Paradis V, et al. Genetics, genomics, and proteomics: implications for the diagnosis and the treatment of chronic hepatitis C. Semin Liver Dis 2007 Feb; 27 (1): 13-27
    • (2007) Semin Liver Dis , vol.27 , Issue.1 , pp. 13-27
    • Asselah, T.1    Bieche, I.2    Paradis, V.3
  • 43
    • 0034252849 scopus 로고    scopus 로고
    • Tumor necrosis factor gene polymorphisms in patients with cirrhosis from chronic hepatitis C virus infection
    • Aug;
    • Yee LJ, Tang J, Herrera J, et al. Tumor necrosis factor gene polymorphisms in patients with cirrhosis from chronic hepatitis C virus infection. Genes Immun 2000 Aug; 1 (6): 386-90
    • (2000) Genes Immun , vol.1 , Issue.6 , pp. 386-390
    • Yee, L.J.1    Tang, J.2    Herrera, J.3
  • 44
    • 27744512909 scopus 로고    scopus 로고
    • TNF alpha genotype affects TNF alpha release, insulin sensitivity and the severity of liver disease in HCV chronic hepatitis
    • Dec;
    • Valenti L, Pulixi E, Fracanzani AL, et al. TNF alpha genotype affects TNF alpha release, insulin sensitivity and the severity of liver disease in HCV chronic hepatitis. J Hepatol 2005 Dec; 43 (6): 944-50
    • (2005) J Hepatol , vol.43 , Issue.6 , pp. 944-950
    • Valenti, L.1    Pulixi, E.2    Fracanzani, A.L.3
  • 45
    • 0347382508 scopus 로고    scopus 로고
    • Cytokine gene polymorphisms and the susceptibility to liver cirrhosis in patients with chronic hepatitis C
    • Dec;
    • Bahr MJ, el Menuawy M, Boeker KHW, et al. Cytokine gene polymorphisms and the susceptibility to liver cirrhosis in patients with chronic hepatitis C. Liver Int 2003 Dec; 23 (6): 420-5
    • (2003) Liver Int , vol.23 , Issue.6 , pp. 420-425
    • Bahr, M.J.1    el Menuawy, M.2    Boeker, K.H.W.3
  • 46
    • 0042856824 scopus 로고    scopus 로고
    • Polymorphisms in tumour necrosis factor-alpha, transforming growth factor-beta, interleukin-10, interleukin-6, interferon-gamma, and outcome of hepatitis C virus infection
    • Oct;
    • Barrett S, Collins M, Kenny C, et al. Polymorphisms in tumour necrosis factor-alpha, transforming growth factor-beta, interleukin-10, interleukin-6, interferon-gamma, and outcome of hepatitis C virus infection. J Med Virol 2003 Oct; 71 (2): 212-8
    • (2003) J Med Virol , vol.71 , Issue.2 , pp. 212-218
    • Barrett, S.1    Collins, M.2    Kenny, C.3
  • 47
    • 0034024356 scopus 로고    scopus 로고
    • Host genetic factors influence disease progression in chronic hepatitis C
    • Apr;
    • Powell EE, Edwards-Smith CJ, Hay JL, et al. Host genetic factors influence disease progression in chronic hepatitis C. Hepatology 2000 Apr; 31 (4): 828-33
    • (2000) Hepatology , vol.31 , Issue.4 , pp. 828-833
    • Powell, E.E.1    Edwards-Smith, C.J.2    Hay, J.L.3
  • 48
    • 0036126282 scopus 로고    scopus 로고
    • Tumor necrosis factor genetic polymorphisms and response to antiviral therapy in patients with chronic hepatitis C
    • Mar;
    • Rosen HR, McHutchison JG, Conrad AJ, et al. Tumor necrosis factor genetic polymorphisms and response to antiviral therapy in patients with chronic hepatitis C. Am J Gastroenterol 2002 Mar; 97 (3): 714-20
    • (2002) Am J Gastroenterol , vol.97 , Issue.3 , pp. 714-720
    • Rosen, H.R.1    McHutchison, J.G.2    Conrad, A.J.3
  • 49
    • 0038460862 scopus 로고    scopus 로고
    • Tumor necrosis factor alpha promoter polymorphisms at position -308 in Taiwanese chronic hepatitis C patients treated with interferon-alpha
    • Jun;
    • Yu ML, Dai CY, Chiu CC, et al. Tumor necrosis factor alpha promoter polymorphisms at position -308 in Taiwanese chronic hepatitis C patients treated with interferon-alpha. Antiviral Res 2003 Jun; 59 (1): 35-40
    • (2003) Antiviral Res , vol.59 , Issue.1 , pp. 35-40
    • Yu, M.L.1    Dai, C.Y.2    Chiu, C.C.3
  • 50
    • 33748516140 scopus 로고    scopus 로고
    • Gender susceptibility to chronic hepatitis C virus infection associated with interleukin 10 promoter polymorphism
    • Sep;
    • Paladino N, Fainboim H, Theiler G, et al. Gender susceptibility to chronic hepatitis C virus infection associated with interleukin 10 promoter polymorphism. J Virol 2006 Sep; 80 (18): 9144-50
    • (2006) J Virol , vol.80 , Issue.18 , pp. 9144-9150
    • Paladino, N.1    Fainboim, H.2    Theiler, G.3
  • 51
    • 30444455025 scopus 로고    scopus 로고
    • Effect of cytokine gene polymorphism on histological activity index, viral load and response to treatment in patients with chronic hepatitis C genotype 3
    • Abbas Z, Moatter T, Hussainy A, et al. Effect of cytokine gene polymorphism on histological activity index, viral load and response to treatment in patients with chronic hepatitis C genotype 3. World J Gastroenterol 2005; 11: 6656-61
    • (2005) World J Gastroenterol , vol.11 , pp. 6656-6661
    • Abbas, Z.1    Moatter, T.2    Hussainy, A.3
  • 52
    • 0141889852 scopus 로고    scopus 로고
    • Interleukin-10 promoter polymorphisms and the outcome of hepatitis C virus infection
    • Sep;
    • Knapp S, Hennig BJW, Frodsham AJ, et al. Interleukin-10 promoter polymorphisms and the outcome of hepatitis C virus infection. Immunogenetics 2003 Sep; 55 (6): 362-9
    • (2003) Immunogenetics , vol.55 , Issue.6 , pp. 362-369
    • Knapp, S.1    Hennig, B.J.W.2    Frodsham, A.J.3
  • 53
    • 2342615651 scopus 로고    scopus 로고
    • Single nucleotide polymorphisms in the interferon-gamma and interleukin-10 genes do not influence chronic hepatitis C severity or T-cell reactivity to hepatitis C virus
    • Apr;
    • Abbott WGH, Rigopoulou E, Haigh P, et al. Single nucleotide polymorphisms in the interferon-gamma and interleukin-10 genes do not influence chronic hepatitis C severity or T-cell reactivity to hepatitis C virus. Liver Int 2004 Apr; 24 (2): 90-7
    • (2004) Liver Int , vol.24 , Issue.2 , pp. 90-97
    • Abbott, W.G.H.1    Rigopoulou, E.2    Haigh, P.3
  • 54
    • 0344796403 scopus 로고    scopus 로고
    • Association of genetic variants of the chemokine receptor MRS and its ligands, RANTES and MCP-2, with outcome of HCV infection
    • Dec;
    • Hellier S, Frodsham AJ, Hennig BJW, et al. Association of genetic variants of the chemokine receptor MRS and its ligands, RANTES and MCP-2, with outcome of HCV infection. Hepatology 2003 Dec; 38 (6): 1468-76
    • (2003) Hepatology , vol.38 , Issue.6 , pp. 1468-1476
    • Hellier, S.1    Frodsham, A.J.2    Hennig, B.J.W.3
  • 55
    • 30544436224 scopus 로고    scopus 로고
    • A combination of genetic polymorphisms increases the risk of progressive disease in chronic hepatitis C
    • Jul;
    • Richardson MM, Powell EE, Barrie HD, et al. A combination of genetic polymorphisms increases the risk of progressive disease in chronic hepatitis C. J Med Genet 2005 Jul; 42 (7): 6
    • (2005) J Med Genet , vol.42 , Issue.7 , pp. 6
    • Richardson, M.M.1    Powell, E.E.2    Barrie, H.D.3
  • 56
    • 0037308259 scopus 로고    scopus 로고
    • Associations of chemokine system polymorphisms with clinical outcomes and treatment responses of chronic hepatitis C
    • Feb;
    • Promrat K, McDermott DH, Gonzalez CM, et al. Associations of chemokine system polymorphisms with clinical outcomes and treatment responses of chronic hepatitis C. Gastroenterology 2003 Feb; 124 (2): 352-60
    • (2003) Gastroenterology , vol.124 , Issue.2 , pp. 352-360
    • Promrat, K.1    McDermott, D.H.2    Gonzalez, C.M.3
  • 57
    • 10744232281 scopus 로고    scopus 로고
    • CC chemokine receptor 5 Delta 32 polymorphism in two independent cohorts of hepatitis C virus infected patients without hemophilia
    • Jan;
    • Wasmuth HE, Werth A, Mueller T, et al. CC chemokine receptor 5 Delta 32 polymorphism in two independent cohorts of hepatitis C virus infected patients without hemophilia. J Mol Med 2004 Jan; 82 (1): 64-9
    • (2004) J Mol Med , vol.82 , Issue.1 , pp. 64-69
    • Wasmuth, H.E.1    Werth, A.2    Mueller, T.3
  • 58
    • 2142698141 scopus 로고    scopus 로고
    • Genetic variants in the CCR gene cluster and spontaneous viral elimination in hepatitis C-infected patients
    • May;
    • Mascheretti S, Hinrichsen H, Ross S, et al. Genetic variants in the CCR gene cluster and spontaneous viral elimination in hepatitis C-infected patients. Clin Exper Immunol 2004 May; 136 (2): 328-33
    • (2004) Clin Exper Immunol , vol.136 , Issue.2 , pp. 328-333
    • Mascheretti, S.1    Hinrichsen, H.2    Ross, S.3
  • 59
    • 3242723067 scopus 로고    scopus 로고
    • Analysis of CCR5-Delta 32 and CCR2-V64I polymorphisms in a cohort of Spanish HCV patients using real-time polymerase chain reaction and fluorescence resonance energy transfer technologies
    • Jul;
    • Ruiz-Ferrer M, Barroso N, Antinolo G, et al. Analysis of CCR5-Delta 32 and CCR2-V64I polymorphisms in a cohort of Spanish HCV patients using real-time polymerase chain reaction and fluorescence resonance energy transfer technologies. J Viral Hepat 2004 Jul; 11 (4): 319-23
    • (2004) J Viral Hepat , vol.11 , Issue.4 , pp. 319-323
    • Ruiz-Ferrer, M.1    Barroso, N.2    Antinolo, G.3
  • 60
    • 33747631578 scopus 로고    scopus 로고
    • CCRS Delta 32 mutation does not influence the susceptibility to HCV infection, severity of liver disease and response to therapy in patients with chronic hepatitis C
    • Aug;
    • Goyal A, Suneetha PV, Kumar GT, et al. CCRS Delta 32 mutation does not influence the susceptibility to HCV infection, severity of liver disease and response to therapy in patients with chronic hepatitis C. World J Gastroenterol 2006 Aug; 12 (29): 4721-6
    • (2006) World J Gastroenterol , vol.12 , Issue.29 , pp. 4721-4726
    • Goyal, A.1    Suneetha, P.V.2    Kumar, G.T.3
  • 61
    • 22644440543 scopus 로고    scopus 로고
    • The CCR5-D32 mutation: Impact on disease outcome in individuals with hepatitis C infection from a single source
    • Aug;
    • Goulding C, Murphy A, MacDonald G, et al. The CCR5-D32 mutation: impact on disease outcome in individuals with hepatitis C infection from a single source. Gut 2005 Aug; 54 (8): 1157-61
    • (2005) Gut , vol.54 , Issue.8 , pp. 1157-1161
    • Goulding, C.1    Murphy, A.2    MacDonald, G.3
  • 62
    • 0142164891 scopus 로고    scopus 로고
    • Analysis of the transforming growth factor-beta 1 (TGF-beta 1) codon 25 gene polymorphism by LightCycler-analysis in patients with chronic hepatitis C infection
    • Dec;
    • Tag CG, Mengsteab S, Hellerbrand C, et al. Analysis of the transforming growth factor-beta 1 (TGF-beta 1) codon 25 gene polymorphism by LightCycler-analysis in patients with chronic hepatitis C infection. Cytokine 2003 Dec; 24 (5): 173-81
    • (2003) Cytokine , vol.24 , Issue.5 , pp. 173-181
    • Tag, C.G.1    Mengsteab, S.2    Hellerbrand, C.3
  • 63
    • 17144459376 scopus 로고    scopus 로고
    • A novel MCP-1 gene polymorphism is associated with hepatic MCP-1 expression and severity of HCV-related liver disease
    • Oct;
    • Muhlbauer M, Bosserhoff AK, Hartmann A, et al. A novel MCP-1 gene polymorphism is associated with hepatic MCP-1 expression and severity of HCV-related liver disease. Gastroenterology 2003 Oct; 125 (4): 1085-93
    • (2003) Gastroenterology , vol.125 , Issue.4 , pp. 1085-1093
    • Muhlbauer, M.1    Bosserhoff, A.K.2    Hartmann, A.3
  • 64
    • 2942568126 scopus 로고    scopus 로고
    • The-2518 promotor polymorphism in the MCP-1 gene is not associated with liver cirrhosis in chronic hepatitis C virus infection
    • Jun;
    • Glas J, Torok HP, Tonenchi L, et al. The-2518 promotor polymorphism in the MCP-1 gene is not associated with liver cirrhosis in chronic hepatitis C virus infection. Gastroenterology 2004 Jun; 126 (7): 1930-1
    • (2004) Gastroenterology , vol.126 , Issue.7 , pp. 1930-1931
    • Glas, J.1    Torok, H.P.2    Tonenchi, L.3
  • 65
    • 26844501091 scopus 로고    scopus 로고
    • No role of the-2518 promoter polymorphism of monocyte chemotactic protein-1 in chronic hepatitis C
    • Oct;
    • Bonkovsky HL, Salek J. No role of the-2518 promoter polymorphism of monocyte chemotactic protein-1 in chronic hepatitis C. Gastroenterology 2005 Oct; 129 (4): 1361-2
    • (2005) Gastroenterology , vol.129 , Issue.4 , pp. 1361-1362
    • Bonkovsky, H.L.1    Salek, J.2
  • 66
    • 33646387993 scopus 로고    scopus 로고
    • Lack of association between microsomal triglyceride transfer protein gene polymorphism and liver steatosis in HCV-infected patients
    • Jun;
    • Petit JM, Masson D, Minello A, et al. Lack of association between microsomal triglyceride transfer protein gene polymorphism and liver steatosis in HCV-infected patients. Mol Genet Metab 2006 Jun; 88 (2): 196-8
    • (2006) Mol Genet Metab , vol.88 , Issue.2 , pp. 196-198
    • Petit, J.M.1    Masson, D.2    Minello, A.3
  • 67
    • 0033369104 scopus 로고    scopus 로고
    • Are haemochromatosis mutations related to the severity of liver disease in hepatitis C virus infection?
    • Martinelli ALC, Franco RF, Villanova MG, et al. Are haemochromatosis mutations related to the severity of liver disease in hepatitis C virus infection? Acta Haematol 1999; 102 (3): 152-6
    • (1999) Acta Haematol , vol.102 , Issue.3 , pp. 152-156
    • Martinelli, A.L.C.1    Franco, R.F.2    Villanova, M.G.3
  • 68
    • 0031801787 scopus 로고    scopus 로고
    • Heterozygosity for hereditary hemochromatosis is associated with more fibrosis in chronic hepatitis C
    • Jun;
    • Smith BC, Grove J, Guzail MA, et al. Heterozygosity for hereditary hemochromatosis is associated with more fibrosis in chronic hepatitis C. Hepatology 1998 Jun; 27 (6): 1695-9
    • (1998) Hepatology , vol.27 , Issue.6 , pp. 1695-1699
    • Smith, B.C.1    Grove, J.2    Guzail, M.A.3
  • 69
    • 0037336495 scopus 로고    scopus 로고
    • HFE mutations and chronic hepatitis C: H63D and C282Y heterozygosity are independent risk factors for liver fibrosis and cirrhosis
    • Mar;
    • Erhardt A, Maschner-Olberg A, Mellenthin C, et al. HFE mutations and chronic hepatitis C: H63D and C282Y heterozygosity are independent risk factors for liver fibrosis and cirrhosis. J Hepatol 2003 Mar; 38 (3): 335-42
    • (2003) J Hepatol , vol.38 , Issue.3 , pp. 335-342
    • Erhardt, A.1    Maschner-Olberg, A.2    Mellenthin, C.3
  • 70
    • 0346843108 scopus 로고    scopus 로고
    • Hemochromatosis and transferrin receptor gene polymorphisms in chronic hepatitis C: Impact on iron status, liver injury and HCV genotype
    • Dec;
    • Gehrke SG, Stremmel W, Mathes I, et al. Hemochromatosis and transferrin receptor gene polymorphisms in chronic hepatitis C: impact on iron status, liver injury and HCV genotype. J Mol Med 2003 Dec; 81 (12): 780-7
    • (2003) J Mol Med , vol.81 , Issue.12 , pp. 780-787
    • Gehrke, S.G.1    Stremmel, W.2    Mathes, I.3
  • 71
    • 0344129013 scopus 로고    scopus 로고
    • Liver iron accumulation in patients with chronic active hepatitis C: Prevalence and role of hemochromatosis gene mutations and relationship with hepatic histological lesions
    • Dec;
    • Hezode C, Cazeneuve C, Coue O, et al. Liver iron accumulation in patients with chronic active hepatitis C: prevalence and role of hemochromatosis gene mutations and relationship with hepatic histological lesions. J Hepatol 1999 Dec; 31 (6): 979-84
    • (1999) J Hepatol , vol.31 , Issue.6 , pp. 979-984
    • Hezode, C.1    Cazeneuve, C.2    Coue, O.3
  • 72
    • 0036155984 scopus 로고    scopus 로고
    • The role of iron and haemochromatosis gene mutations in the progression of liver disease in chronic hepatitis C
    • Thorburn D, Curry G, Spooner R, et al. The role of iron and haemochromatosis gene mutations in the progression of liver disease in chronic hepatitis C. Gut 2002; 50 (2): 248-52
    • (2002) Gut , vol.50 , Issue.2 , pp. 248-252
    • Thorburn, D.1    Curry, G.2    Spooner, R.3
  • 73
    • 12144285965 scopus 로고    scopus 로고
    • Influence of HFE gene polymorphism on the progression and treatment of chronic hepatitis C
    • Mar;
    • Lebray P, Zylberberg H, Hue S, et al. Influence of HFE gene polymorphism on the progression and treatment of chronic hepatitis C. J Viral Hepat 2004 Mar; 11 (2): 175-82
    • (2004) J Viral Hepat , vol.11 , Issue.2 , pp. 175-182
    • Lebray, P.1    Zylberberg, H.2    Hue, S.3
  • 74
    • 24044460753 scopus 로고    scopus 로고
    • Polymorphisms of the renin-angiotensin system and the severity of fibrosis in chronic hepatitis C virus infection
    • Sep;
    • Forrest EH, Thorburn D, Spence E, et al. Polymorphisms of the renin-angiotensin system and the severity of fibrosis in chronic hepatitis C virus infection. J Viral Hepat 2005 Sep; 12 (5): 519-24
    • (2005) J Viral Hepat , vol.12 , Issue.5 , pp. 519-524
    • Forrest, E.H.1    Thorburn, D.2    Spence, E.3
  • 75
    • 0032428331 scopus 로고    scopus 로고
    • Modulation of life and death by the TNF receptor superfamily
    • Dec;
    • Baker SJ, Reddy EP. Modulation of life and death by the TNF receptor superfamily. Oncogene 1998 Dec; 17 (25): 3261-70
    • (1998) Oncogene , vol.17 , Issue.25 , pp. 3261-3270
    • Baker, S.J.1    Reddy, E.P.2
  • 76
    • 2442608884 scopus 로고    scopus 로고
    • TGF-beta and TNF-alpha: Antagonistic cytokines controlling type I collagen gene expression
    • Aug;
    • Verrecchia F, Mauviel A. TGF-beta and TNF-alpha: antagonistic cytokines controlling type I collagen gene expression. Cell Signal 2004 Aug; 16 (8): 873-80
    • (2004) Cell Signal , vol.16 , Issue.8 , pp. 873-880
    • Verrecchia, F.1    Mauviel, A.2
  • 77
    • 0035062021 scopus 로고    scopus 로고
    • Interleukin-10 and the interleukin-10 receptor
    • Moore KW, Malefyt RD, Coffman RL, et al. Interleukin-10 and the interleukin-10 receptor. Ann Rev Immunol 2001; 19: 683-765
    • (2001) Ann Rev Immunol , vol.19 , pp. 683-765
    • Moore, K.W.1    Malefyt, R.D.2    Coffman, R.L.3
  • 78
    • 0031972755 scopus 로고    scopus 로고
    • Expression of interleukin-10 by in vitro and in vivo activated hepatic stellate cells
    • Jan;
    • Wang SC, Ohata M, Schrum L, et al. Expression of interleukin-10 by in vitro and in vivo activated hepatic stellate cells. J Biol Chem 1998 Jan; 273 (1): 302-8
    • (1998) J Biol Chem , vol.273 , Issue.1 , pp. 302-308
    • Wang, S.C.1    Ohata, M.2    Schrum, L.3
  • 79
    • 0031017238 scopus 로고    scopus 로고
    • An investigation of polymorphism in the interleukin-10 gene promoter
    • Feb;
    • Turner DM, Williams DM, Sankaran D, et al. An investigation of polymorphism in the interleukin-10 gene promoter. Eur J Immunogenet 1997 Feb; 24 (1): 1-8
    • (1997) Eur J Immunogenet , vol.24 , Issue.1 , pp. 1-8
    • Turner, D.M.1    Williams, D.M.2    Sankaran, D.3
  • 80
    • 15844388931 scopus 로고    scopus 로고
    • Homozygous defect in HIV-1 coreceptor accounts for resistance of some multiply-exposed individuals to HIV-1 infection
    • Aug;
    • Liu R, Paxton WA, Choe S, et al. Homozygous defect in HIV-1 coreceptor accounts for resistance of some multiply-exposed individuals to HIV-1 infection. Cell 1996 Aug; 86 (3): 367-77
    • (1996) Cell , vol.86 , Issue.3 , pp. 367-377
    • Liu, R.1    Paxton, W.A.2    Choe, S.3
  • 81
    • 16044373004 scopus 로고    scopus 로고
    • Resistance to HIV-1 infection in Caucasian individuals bearing mutant alleles of the CCR-5 chemokine receptor gene
    • Samson M, Libert F, Doranz BJ, et al. Resistance to HIV-1 infection in Caucasian individuals bearing mutant alleles of the CCR-5 chemokine receptor gene. Nature 1996; 382 (6593): 722-5
    • (1996) Nature , vol.382 , Issue.6593 , pp. 722-725
    • Samson, M.1    Libert, F.2    Doranz, B.J.3
  • 82
    • 0029026662 scopus 로고
    • Transforming growth factor-beta (TBF-beta): A key role in liver fibrogenesis
    • Bedossa P, Paradis V. Transforming growth factor-beta (TBF-beta): a key role in liver fibrogenesis. J Hepatol 1995; 22: 37-42
    • (1995) J Hepatol , vol.22 , pp. 37-42
    • Bedossa, P.1    Paradis, V.2
  • 83
    • 0032573136 scopus 로고    scopus 로고
    • Genotypic variation in the transforming growth factor-beta1 gene: Association with transforming growth factor-pi production, fibrotic lung disease, and graft fibrosis after lung transplantation
    • Oct;
    • Awad MR, El Gamel A, Hasleton P, et al. Genotypic variation in the transforming growth factor-beta1 gene: association with transforming growth factor-pi production, fibrotic lung disease, and graft fibrosis after lung transplantation. Transplantation 1998 Oct; 66 (8): 1014-20
    • (1998) Transplantation , vol.66 , Issue.8 , pp. 1014-1020
    • Awad, M.R.1    El Gamel, A.2    Hasleton, P.3
  • 85
    • 0032934278 scopus 로고    scopus 로고
    • Monocyte chemotactic protein-1 as a chemoattractant for human hepatic stellate cells
    • Jan;
    • Marra F, Romanelli RG, Giannini C, et al. Monocyte chemotactic protein-1 as a chemoattractant for human hepatic stellate cells. Hepatology 1999 Jan; 29 (1): 140-8
    • (1999) Hepatology , vol.29 , Issue.1 , pp. 140-148
    • Marra, F.1    Romanelli, R.G.2    Giannini, C.3
  • 86
    • 0033532605 scopus 로고    scopus 로고
    • A novel polymorphism in the MCP-1 gene regulatory region that influences MCP-1 expression
    • Jun;
    • Rovin BH, Lu L, Saxena R. A novel polymorphism in the MCP-1 gene regulatory region that influences MCP-1 expression. Biochem Biophys Res Commun 1999 Jun; 259 (2): 344-8
    • (1999) Biochem Biophys Res Commun , vol.259 , Issue.2 , pp. 344-348
    • Rovin, B.H.1    Lu, L.2    Saxena, R.3
  • 87
    • 9344224529 scopus 로고    scopus 로고
    • A novel MHC class I-like gene is mutated in patients with hereditary haemochromatosis
    • Aug;
    • Feder JN, Gnirke A, Thomas W, et al. A novel MHC class I-like gene is mutated in patients with hereditary haemochromatosis. Nature Genet 1996 Aug; 13 (4): 399-408
    • (1996) Nature Genet , vol.13 , Issue.4 , pp. 399-408
    • Feder, J.N.1    Gnirke, A.2    Thomas, W.3
  • 89
    • 0037164344 scopus 로고    scopus 로고
    • Genetics of haemochromatosis
    • Nov;
    • Bomford A. Genetics of haemochromatosis. Lancet 2002 Nov; 360 (9346): 1673-81
    • (2002) Lancet , vol.360 , Issue.9346 , pp. 1673-1681
    • Bomford, A.1
  • 90
    • 0042384686 scopus 로고    scopus 로고
    • Iron-induced oxidant stress in alcoholic liver fibrogenesis
    • Jun;
    • Pietrangelo A. Iron-induced oxidant stress in alcoholic liver fibrogenesis. Alcohol 2003 Jun; 30 (2): 121-9
    • (2003) Alcohol , vol.30 , Issue.2 , pp. 121-129
    • Pietrangelo, A.1
  • 91
    • 0037310944 scopus 로고    scopus 로고
    • Hepatitis C, iron status, and disease severity: Relationship with HFE mutations
    • Feb;
    • Tung BY, Emond MJ, Bronner MP, et al. Hepatitis C, iron status, and disease severity: relationship with HFE mutations. Gastroenterology 2003 Feb; 124 (2): 318-26
    • (2003) Gastroenterology , vol.124 , Issue.2 , pp. 318-326
    • Tung, B.Y.1    Emond, M.J.2    Bronner, M.P.3
  • 92
    • 0030924446 scopus 로고    scopus 로고
    • Angiotensin II in renal fibrosis: Should TGF-beta rather than blood pressure be the therapeutic target?
    • Sep;
    • Noble NA, Border WA. Angiotensin II in renal fibrosis: should TGF-beta rather than blood pressure be the therapeutic target? Semin Nephrol 1997 Sep; 17 (5): 455-66
    • (1997) Semin Nephrol , vol.17 , Issue.5 , pp. 455-466
    • Noble, N.A.1    Border, W.A.2
  • 93
    • 0030893575 scopus 로고    scopus 로고
    • A nucleotide substitution in the promoter of human angiotensinogen is associated with essential hypertension and affects basal transcription in vitro
    • Apr;
    • Inoue I, Nakajima T, Williams CS, et al. A nucleotide substitution in the promoter of human angiotensinogen is associated with essential hypertension and affects basal transcription in vitro. J Clin Invest 1997 Apr; 99 (7): 1786-97
    • (1997) J Clin Invest , vol.99 , Issue.7 , pp. 1786-1797
    • Inoue, I.1    Nakajima, T.2    Williams, C.S.3
  • 94
    • 0038813649 scopus 로고    scopus 로고
    • Genetic associations: False or true?
    • Apr;
    • Ioannidis JPA. Genetic associations: false or true? Trends Mol Med 2003 Apr; 9 (4): 135-8
    • (2003) Trends Mol Med , vol.9 , Issue.4 , pp. 135-138
    • Ioannidis, J.P.A.1
  • 95
    • 33745592507 scopus 로고    scopus 로고
    • Statistical false positive or true disease pathway?
    • Jul;
    • Todd JA. Statistical false positive or true disease pathway? Nature Genet 2006 Jul; 38 (7): 731-3
    • (2006) Nature Genet , vol.38 , Issue.7 , pp. 731-733
    • Todd, J.A.1
  • 96
    • 34548301514 scopus 로고    scopus 로고
    • A 7 gene signature identifies the risk of developing cirrhosis in patients with chronic hepatitis C
    • Aug;
    • Huang HJ, Shiffman ML, Friedman S, et al. A 7 gene signature identifies the risk of developing cirrhosis in patients with chronic hepatitis C. Hepatology 2007 Aug; 46 (2): 297-306
    • (2007) Hepatology , vol.46 , Issue.2 , pp. 297-306
    • Huang, H.J.1    Shiffman, M.L.2    Friedman, S.3
  • 97
    • 33750211858 scopus 로고    scopus 로고
    • A gene-centric approach to genome-wide association studies
    • Nov;
    • Jorgenson E, Witte JS. A gene-centric approach to genome-wide association studies. Nature Rev Genet 2006 Nov; 7 (11): 885-91
    • (2006) Nature Rev Genet , vol.7 , Issue.11 , pp. 885-891
    • Jorgenson, E.1    Witte, J.S.2
  • 98
    • 38949213990 scopus 로고    scopus 로고
    • Commentary: Genetic association studies see light at the end of the tunnel
    • Feb;
    • Frayling TM. Commentary: genetic association studies see light at the end of the tunnel. Int J Epidemiol 2008 Feb; 37 (1): 133-5
    • (2008) Int J Epidemiol , vol.37 , Issue.1 , pp. 133-135
    • Frayling, T.M.1
  • 99
    • 38949094880 scopus 로고    scopus 로고
    • Assessment of cumulative evidence on genetic associations: Interim guidelines
    • Feb;
    • Ioannidis JP, Boffetta P, Little J, et al. Assessment of cumulative evidence on genetic associations: interim guidelines. Int J Epidemiol 2008 Feb; 37 (1): 120-32
    • (2008) Int J Epidemiol , vol.37 , Issue.1 , pp. 120-132
    • Ioannidis, J.P.1    Boffetta, P.2    Little, J.3
  • 100
    • 0031041924 scopus 로고    scopus 로고
    • Morbidity and mortality in compensated cirrhosis type C: A retrospective follow-up study of 384 patients
    • Feb;
    • Fattovich G, Giustina G, Degos F, et al. Morbidity and mortality in compensated cirrhosis type C: a retrospective follow-up study of 384 patients. Gastroenterology 1997 Feb; 112 (2): 463-72
    • (1997) Gastroenterology , vol.112 , Issue.2 , pp. 463-472
    • Fattovich, G.1    Giustina, G.2    Degos, F.3
  • 101
    • 36549032819 scopus 로고    scopus 로고
    • Insulin resistance and response to therapy in patients infected with chronic hepatitis C virus genotypes 2 and 3
    • Jan;
    • Poustchi H, Negro F, Hui J, et al. Insulin resistance and response to therapy in patients infected with chronic hepatitis C virus genotypes 2 and 3. J Hepatol 2008 Jan; 48 (1): 28-34
    • (2008) J Hepatol , vol.48 , Issue.1 , pp. 28-34
    • Poustchi, H.1    Negro, F.2    Hui, J.3
  • 102
    • 33645114359 scopus 로고    scopus 로고
    • Non-response to antiviral therapy is associated with obesity and increased hepatic expression of suppressor of cytokine signalling 3 (SOCS-3) in patients with chronic hepatitis C, viral genotype 1
    • Apr;
    • Walsh MJ, Jonsson JR, Richardson MM, et al. Non-response to antiviral therapy is associated with obesity and increased hepatic expression of suppressor of cytokine signalling 3 (SOCS-3) in patients with chronic hepatitis C, viral genotype 1. Gut 2006 Apr; 55 (4): 529-35
    • (2006) Gut , vol.55 , Issue.4 , pp. 529-535
    • Walsh, M.J.1    Jonsson, J.R.2    Richardson, M.M.3
  • 103
    • 0034961836 scopus 로고    scopus 로고
    • Angiotensin-converting enzyme inhibition attenuates the progression of rat hepatic fibrosis
    • Jul;
    • Jonsson JR, Clouston AD, Ando Y, et al. Angiotensin-converting enzyme inhibition attenuates the progression of rat hepatic fibrosis. Gastroenterology 2001 Jul; 121 (1): 148-55
    • (2001) Gastroenterology , vol.121 , Issue.1 , pp. 148-155
    • Jonsson, J.R.1    Clouston, A.D.2    Ando, Y.3
  • 104
    • 0034849945 scopus 로고    scopus 로고
    • Effect of angiotensin II type 1 receptor blockade on experimental hepatic fibrogenesis
    • Sep;
    • Paizis G, Gilbert RE, Cooper ME, et al. Effect of angiotensin II type 1 receptor blockade on experimental hepatic fibrogenesis. J Hepatol 2001 Sep; 35 (3): 376-85
    • (2001) J Hepatol , vol.35 , Issue.3 , pp. 376-385
    • Paizis, G.1    Gilbert, R.E.2    Cooper, M.E.3
  • 105
    • 18644369234 scopus 로고    scopus 로고
    • Effect of angiotensin receptor antagonist on liver fibrosis in early stages of chronic hepatitis C
    • Oct;
    • Terui Y, Saito T, Watanabe H, et al. Effect of angiotensin receptor antagonist on liver fibrosis in early stages of chronic hepatitis C. Hepatology 2002 Oct; 36 (4): 1022
    • (2002) Hepatology , vol.36 , Issue.4 , pp. 1022
    • Terui, Y.1    Saito, T.2    Watanabe, H.3
  • 106
    • 7044222556 scopus 로고    scopus 로고
    • Therapeutic efficacy of an angiotensin II receptor antagonist in patients with nonalcoholic steatohepatitis
    • Nov;
    • Yokohama S, Yoneda M, Haneda M, et al. Therapeutic efficacy of an angiotensin II receptor antagonist in patients with nonalcoholic steatohepatitis. Hepatology 2004 Nov; 40 (5): 1222-5
    • (2004) Hepatology , vol.40 , Issue.5 , pp. 1222-1225
    • Yokohama, S.1    Yoneda, M.2    Haneda, M.3
  • 107
    • 33644499498 scopus 로고    scopus 로고
    • Reversal of hepatic fibrosis: Fact or fantasy?
    • Feb;
    • Friedman SL, Bansal MB. Reversal of hepatic fibrosis: fact or fantasy? Hepatology 2006 Feb; 43 (2): S82-8
    • (2006) Hepatology , vol.43 , Issue.2
    • Friedman, S.L.1    Bansal, M.B.2
  • 108
    • 0037456772 scopus 로고    scopus 로고
    • The importance of race and ethnic background in biomedical research and clinical practice
    • Mar;
    • Burchard EG, Ziv E, Coyle N, et al. The importance of race and ethnic background in biomedical research and clinical practice. N Engl J Med 2003 Mar; 348 (12): 1170-5
    • (2003) N Engl J Med , vol.348 , Issue.12 , pp. 1170-1175
    • Burchard, E.G.1    Ziv, E.2    Coyle, N.3
  • 109
    • 0036950351 scopus 로고    scopus 로고
    • Single nucleotide polymorphisms in innate immunity genes: Abundant variation and potential role in complex human disease
    • Dec;
    • Lazarus R, Vercelli D, Palmer LJ, et al. Single nucleotide polymorphisms in innate immunity genes: abundant variation and potential role in complex human disease. Immunol Rev 2002 Dec; 190 (1): 9-25
    • (2002) Immunol Rev , vol.190 , Issue.1 , pp. 9-25
    • Lazarus, R.1    Vercelli, D.2    Palmer, L.J.3
  • 110
    • 38349032004 scopus 로고    scopus 로고
    • Successful design and conduct of genome-wide association studies
    • Oct;
    • Amos CI. Successful design and conduct of genome-wide association studies. Hum Mol Genet 2007 Oct; 16: R220-5
    • (2007) Hum Mol Genet , vol.16
    • Amos, C.I.1
  • 111
    • 21344446513 scopus 로고    scopus 로고
    • Steatosis: Co-factor in other liver diseases
    • Jul;
    • Powell EE, Jonsson JR, Clouston AD. Steatosis: co-factor in other liver diseases. Hepatology 2005 Jul; 42 (1): 5-13
    • (2005) Hepatology , vol.42 , Issue.1 , pp. 5-13
    • Powell, E.E.1    Jonsson, J.R.2    Clouston, A.D.3
  • 112
    • 0030436442 scopus 로고    scopus 로고
    • Histological features predictive of liver fibrosis in chronic hepatitis C infection
    • Dec;
    • Paradis V, Mathurin P, Laurent A, et al. Histological features predictive of liver fibrosis in chronic hepatitis C infection. J Clin Pathol 1996 Dec; 49 (12): 998-1004
    • (1996) J Clin Pathol , vol.49 , Issue.12 , pp. 998-1004
    • Paradis, V.1    Mathurin, P.2    Laurent, A.3
  • 113
    • 39749096696 scopus 로고    scopus 로고
    • Genetic association studies: From "searching under the lamppost" to "fishing in the pond
    • El-Serag HB, White DL, Mitra N. Genetic association studies: from "searching under the lamppost" to "fishing in the pond". Gastroenterology 2008; 134 (3): 662-4
    • (2008) Gastroenterology , vol.134 , Issue.3 , pp. 662-664
    • El-Serag, H.B.1    White, D.L.2    Mitra, N.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.