Natural history and predictors of disease severity in chronic hepatitis C

Journal of Hepatology

Volumn 44, Issue SUPPL. 1, 2006, Pages

  Massard, Julien ^a   Ratziu, Vlad ^a   Thabut, Dominique ^a   Moussalli, Joseph ^a   Lebray, Pascal ^a   Benhamou, Yves ^a   Poynard, Thierry ^a  

^a PITIÉ SALPÊTRIÈRE HOSPITAL   (France)

Author keywords

Cirrhosis; Fibrosis; Hepatitis C; Natural history

Indexed keywords

ALCOHOL CONSUMPTION; CD4 LYMPHOCYTE COUNT; CD4+ T LYMPHOCYTE; CONFERENCE PAPER; DIABETES MELLITUS; DISEASE COURSE; DISEASE SEVERITY; FATTY LIVER; HEPATITIS C; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; LIVER CIRRHOSIS; NONHUMAN; OBESITY; PATHOGENESIS; PREDICTION; PRIORITY JOURNAL; RISK FACTOR; SEX DIFFERENCE;

DISEASE PROGRESSION; HEPATITIS C, CHRONIC; HUMANS; LIVER CIRRHOSIS; PROGNOSIS; RISK FACTORS; SEVERITY OF ILLNESS INDEX;

EID: 30144431739     PISSN: 01688278     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jhep.2005.11.009     Document Type: Conference Paper

References (61)

1. T. Poynard, M.F. Yuen, V. Ratziu, and C.L. Lai Viral hepatitis C: review Lancet 362 2003 2095 2100
2. T. Poynard, P. Bedossa, P. Opolon, and for the OBSVIRC, METAVIR, CLINIVIR and DOSVIRC Groups Natural history of liver fibrosis progression in patients with chronic hepatitis C Lancet 349 1997 825 832
3. R. Sobesky, P. Mathurin, F. Charlotte, J. Moussalli, M. Olivi, and M. Vidaud Modeling the impact of interferon alfa treatment on liver fibrosis progression in chronic hepatitis C: a dynamic view Gastroenterology 116 1999 378 386
4. R.G. Knodell, K.G. Ishak, W.C. Black, T.S. Chen, R. Craig, and N. Kaplowitz Formulation and application of a numerical scoring system for assessing histological activity in asymptomatic chronic active hepatitis Hepatology 1 1981 431 435
5. K. Ishak, A. Baptista, L. Bianchi, F. Callea, J. De Groote, and F. Gudat Histological grading and staging of chronic hepatitis J Hepatol 22 1995 696 699
6. The METAVIR Cooperative Group Inter- and intra-observer variation in the assessment of liver biopsy of chronic hepatitis C Hepatology 20 1994 15 20
7. P. Bedossa, and T. Poynard An algorithm for the grading of activity in chronic hepatitis C. The METAVIR Cooperative Study Group Hepatology 24 1996 289 293
8. V. Paradis, P. Mathurin, A. Laurent, F. Charlotte, M. Vidaud, and T. Poynard Histological features predictive of liver fibrosis in chronic hepatitis C infection J Clin Pathol 49 1996 998 1004
9. T. Poynard, V. Ratziu, F. Charlotte, Z. Goodman, J. McHutchison, and J. Albrecht Rates and risk factors of liver fibrosis progression in patients with chronic hepatitis C J Hepatol 34 2001 730 739
10. S. Deuffic-Burban, T. Poynard, and A.J. Valleron Quantification of fibrosis progression in patients with chronic hepatitis C using a Markov model J Viral Hepat 9 2002 114 122
11. M. Yano, H. Kumada, M. Kage, K. Ikeda, K. Shimamatsu, and O. Inoue The long term pathological evolution of chronic hepatitis C Hepatology 23 1996 1334 1340
12. C. Datz, M. Cramp, T. Haas, O. Dietze, H. Nitschko, and G. Froesner The natural course of hepatitis C virus infection 18 years after an epidemic outbreak of non-A, non-B hepatitis in a plasmapheresis centre Gut 44 1999 563 567
13. M.G. Ghany, D.E. Kleiner, H. Alter, E. Doo, F. Khokar, and K. Promrat Progression of fibrosis in chronic hepatitis C Gastroenterology 124 2003 97 104
14. A. Regev, M. Berho, L.J. Jeffers, C. Milikowski, E.G. Molina, and N.T. Pyrsopoulos Sampling error and intraobserver variation in liver biopsy in patients with chronic HCV infection Am J Gastroenterol 97 2002 2614 2618
15. G. Colloredo, M. Guido, A. Sonzogni, and G. Leandro Impact of liver biopsy size on histological evaluation of chronic viral hepatitis: the smaller the sample, the milder the disease J Hepatol 39 2003 239 244
16. P. Bedossa, D. Dargère, and V. Paradis Sampling variability of liver fibrosis in chronic hepatitis C Hepatology 38 2003 1449 1457
17. K.A. Gebo, H.F. Herlong, M.S. Torbenson, M.W. Jenckes, G. Chander, and K.G. Ghanem Role of liver biopsy in management of chronic hepatitis C: a systematic review Hepatology 36 2002 S161 S172
18. F. Imbert-Bismut, V. Ratziu, L. Laurence Pieroni, F. Charlotte, Y. Benhamou, and T. Poynard Biochemical markers of liver fibrosis in patients with hepatitis C virus infection: a prospective study Lancet 357 2001 1069 1075
19. T. Poynard, M. Munteanu, F. Imbert-Bismut, F. Charlotte, D. Thabut, and S. Le Calvez Prospective analysis of discordant results between biochemical markers and biopsy in patients with chronic hepatitis C Clin Chem 50 2004 1344 1355
20. T. Poynard, F. Imbert-Bismut, M. Munteanu, D. Messous, R.P. Myers, and D. Thabut Overview of the diagnostic value of biochemical markers of liver fibrosis (FibroTest, HCV-Fibrosure) and necrosis (ActiTest) in patients with chronic hepatitis C Comp Hepatol 3 2004 8
21. T.E. Wiley, M. McCarthy, L. Breidi, M. McCarthy, and T.J. Layden Impact of alcohol on the histological and clinical progression of hepatitis C infection Hepatology 28 1998 805 809
22. Y. Benhamou, M. Bochet, V. Di Martino, F. Charlotte, F. Azria, and A. Coutellier Liver fibrosis progression in human immunodeficiency virus and hepatitis C virus co-infected patients. The multivirc group Hepatology 30 1999 1054 1058
23. D.M. Bissell Sex and hepatic fibrosis Hepatology 29 1999 988 989
24. L.F. Hourigan, G.A. Macdonald, D. Purdie, V.H. Whitehall, C. Shorthouse, and A. Clouston Fibrosis in chronic hepatitis C correlates significantly with body mass index and steatosis Hepatology 29 1999 1215 1219
25. V. Ortiz, M. Berenguer, J.M. Rayon, D. Carrasco, and J. Berenguer Contribution of obesity to hepatitis C-related fibrosis progression Am J Gastroenterol 97 2002 2408 2414
26. M.E. Poynter, and R.A. Daynes Peroxysome proliferator-activated receptor α activation modulates cellular redox status, represses nuclear factor-kB signaling, and reduces inflammatory cytokine production in aging J Biol Chem 273 1998 32833 32841
27. M. Wali, R.F. Harrison, P.J. Gow, and D. Mutimer Advancing donor liver age and rapid fibrosis progression following transplantation for hepatitis C Gut 51 2002 248 252
28. V. Ratziu, M. Munteanu, F. Charlotte, L. Bonyhay, T. Poynard, and LIDO Study Group Fibrogenic impact of high serum glucose in chronic hepatitis C J Hepatol 39 2003 1049 1055
29. V. Di Martino, P. Lebray, R.P. Myers, E. Pannier, V. Paradis, and F. Charlotte Progression of liver fibrosis in women infected with hepatitis C: long-term benefit of estrogen exposure Hepatology 40 2004 1426 1433
30. S. Pol, H. Fontaine, F. Carnot, H. Zylberberg, P. Berthelot, and C. Brechot Predictive factors for development of cirrhosis in parenterally acquired chronic hepatitis C: a comparison between immunocompetent and immunocompromised patients J Hepatol 29 1998 12 19
31. V. Soriano, M. Sulkowski, C. Bergin, A. Hatzakis, P. Cacoub, and C. Katlama Care of patients with chronic hepatitis C and HIV co- infection: recommendations from the HIV-HCV International Panel AIDS 16 2002 813 828
32. T. Poynard, P. Mathurin, C.L. Lai, D. Guyader, R. Poupon, and M.H. Tainturier A comparison of fibrosis progression in chronic liver diseases J Hepatol 38 2003 257 265
33. L. De Moliner, P. Pontisso, G.L. De Salvo, L. Cavalletto, L. Chemello, and A. Alberti Serum and liver HCV RNA levels in patients with chronic hepatitis C: correlation with clinical and histological features Gut 42 1998 856 860
34. L. Roffi, A. Ricci, C. Ogliari, A. Scalori, E. Minola, and G. Colloredo HCV genotypes in Northern Italy: a survey of 1368 histologically proven chronic hepatitis C patients J Hepatol 29 1998 701 706
35. V. Ratziu, M. Saboury, and T. Poynard Worsening of steatosis and fibrosis progression Gut 52 2003 1386 1387
36. T. Poynard, V. Ratziu, J. McHutchison, M. Manns, Z. Goodman, and S. Zeuzem Effect of treatment with peginterferon or interferon alfa-2b and ribavirin on steatosis in patients infected with hepatitis C Hepatology 38 2003 75 85
37. L. Castera, C. Hezode, F. Roudot-Thoraval, A. Bastie, E.S. Zafrani, and J.M. Pawlotsky Worsening of steatosis is an independent factor of fibrosis progression in untreated patients with chronic hepatitis C and paired liver biopsies Gut 52 2003 288 292
38. P. Mathurin, J. Moussalli, J.F. Cadranel, V. Thibault, F. Charlotte, and P. Dumouchel Slow progression rate of fibrosis in hepatitis C virus patients with persistently normal alanine transaminase activity Hepatology 27 1998 868 872
39. A. Alberti, F. Noventa, L. Benvegnu, S. Boccato, and A. Gatta Prevalence of liver disease in a population of asymptomatic persons with hepatitis C virus infection Ann Intern Med 137 2002 961 964
40. D. Thabut, S. Le Calvez, V. Thibault, J. Massard, C. d'Arondel, and J. Moussalli Hepatitis C in 2,410 patients 65 years or older. A severe and neglected curable disease? Hepatology 2003 38
41. A. Czaja, H. Carpenter, P. Santrach, and S. Moore Host- and disease-specific factors affecting steatosis in chronic hepatitis C J Hepatol 29 1998 198 206
42. L. Rubbia-Brandt, R. Quadri, K. Abid, E. Giostra, P.J. Male, and G. Mentha Hepatocyte steatosis is a cytopathic effect of hepatitis C virus genotype 3 J Hepatol 33 2000 106 115
43. G. Fiore, G. Fera, N. Napoli, F. Vella, and O. Schiraldi Liver steatosis and chronic hepatitis C: a spurious association? Eur J Gastroenterol Hepatol 8 1996 125 129
44. L.E. Adinolfi, M. Gambardella, A. Andreana, M.F. Tripodi, R. Utili, and G. Ruggiero Steatosis accelerates the progression of liver damage of chronic hepatitis C patients and correlates with specific HCV genotype and visceral obesity Hepatology 33 2001 1358 1364
45. S.J. Hwang, J.C. Luo, C.W. Chu, C.R. Lai, C.L. Lu, and S.H. Tsay Hepatic steatosis in chronic hepatitis C virus infection: prevalence and clinical correlation J Gastroenterol Hepatol 16 2001 190 195
46. J. Westin, H. Nordlinder, M. Lagging, G. Norkrans, and R. Wejstal Steatosis accelerates fibrosis development over time in hepatitis C virus genotype 3 infected patients J Hepatol 37 2002 837 842
47. V.S. Wong, D.G. Wight, C.R. Palmer, and G.J. Alexander Fibrosis and other histological features in chronic hepatitis C virus infection: a statistical model J Clin Pathol 49 1996 465 469
48. J.P. Ong, Z.M. Younossi, C. Speer, A. Olano, T. Gramlich, and N. Boparai Chronic hepatitis C and superimposed nonalcoholic fatty liver disease Liver 21 2001 266 271
49. K. Ohata, K. Hamasaki, K. Toriyama, K. Matsumoto, A. Saeki, and K. Yanagi Hepatic steatosis is a risk factor for hepatocellular carcinoma in patients with chronic hepatitis C virus infection Cancer 97 2003 3036 3043
50. H. Knobler, R. Schihmanter, A. Zifroni, G. Fenakel, and A. Schattner Increased risk of type 2 diabetes in noncirrhotic patients with chronic hepatitis C virus infection Mayo Clin Proc 75 2000 355 359
51. J.-M. Petit, J.-B. Bour, C. Galland-Jos, A. Minello, B. Verges, and M. Guiguet Risk factors for diabetes mellitus and early insulin resistance in chronic hepatitis C J Hepatol 35 2001 279 283
52. A. Monto, J. Alonzo, J.J. Watson, C. Grunfeld, and T.L. Wright Steatosis in chronic hepatitis C: relative contributions of obesity, diabetes mellitus, and alcohol Hepatology 36 2002 729 736
53. V. Ortiz, M. Berenguer, J.M. Rayon, D. Carrasco, and J. Berenguer Contribution of obesity to hepatitis C-related fibrosis progression Am J Gastroenterol 97 2002 2408 2414
54. L.F. Hourigan, G.E. MacDonald, D. Purdie, V.H. Whitehall, C. Shorthouse, and A. Clouston Fibrosis in chronic hepatitis C correlates significantly with body mass index and steatosis Hepatology 29 1999 1215 1219
55. A.J. McCullough, and Y. Falck-Ytter Body composition and hepatic steatosis as precursors for fibrotic liver disease Hepatology 29 1999 1328 1330
56. J.G. Kral, F. Schaffner, R.N. Pierson, and J. Wang Body fat topography as an independent predictor of fatty liver Metabolism 42 1993 548 551
57. I.J. Hickman, A.D. Clouston, G.A. Macdonald, D.M. Purdie, J.B. Prins, and S. Ash Effect of weight reduction on liver histology and biochemistry in patients with chronic hepatitis C Gut 51 2002 89 94
58. J.G. Kral, S.N. Thung, S. Biron, F.S. Hould, S. Lebel, and S. Marceau Effects of surgical treatment of the metabolic syndrome on liver fibrosis and cirrhosis Surgery 135 2004 48 58
59. L. Rubbia-Brandt, P. Fabris, S. Paganin, G. Leandro, P.J. Male, and E. Giostra Steatosis affects chronic hepatitis C progression in a genotype specific way Gut 53 2004 406 412
60. J.M. Hui, A. Sud, G.C. Farrell, P. Bandara, K. Byth, and J.G. Kench Insulin resistance is associated with chronic hepatitis C and virus infection fibrosis progression Gastroenterology 125 2003 1695 1704
61. L. Fartoux, O. Chazouillères, D. Wendum, R. Poupon, and L. Serfaty Impact of steatosis on progression of fibrosis in patients with mild hepatitis C Hepatology 41 2005 82 87