HCV inhibits antigen processing and presentation and induces oxidative stress response in gastric mucosa

Proteomics - Clinical Applications

Volumn 2, Issue 9, 2008, Pages 1290-1299

  De Re, Valli ^a   Simula, Maria Paola ^a   Cannizzaro, Renato ^a   Sansonno, Domenico ^b   Canzonieri, Vincenzo ^a   Gloghini, Annunziata ^a   Carbone, Antonino ^c   Colombatti, Alfonso ^a,d   Marin, Maria Dolores ^a   De Zorzi, Mariangela ^a   Toffoli, Giuseppe ^a  

^a CENTRO DI RIFERIMENTO ONCOLOGICO   (Italy)

^b UNIVERSITY OF BARI MEDICAL SCHOOL   (Italy)

^c NATIONAL CANCER INSTITUTE   (Italy)

^d UNIVERSITY OF UDINE   (Italy)

Author keywords

Cancer; Hepatitis C virus; Inflammation; Proteomic; Ubiquinol cytochrome C reductase

Indexed keywords

UBIQUINOL CYTOCHROME C REDUCTASE;

AMINO ACID SEQUENCE; ANTIGEN PRESENTATION; ARTICLE; CELL MATURATION; CELL SURVIVAL; CELLULAR STRESS RESPONSE; CLINICAL ARTICLE; CONTROLLED STUDY; DISEASE COURSE; ENDOPLASMIC RETICULUM STRESS; HEPATITIS C; HUMAN; HUMAN TISSUE; IMMUNE RESPONSE; IMMUNOHISTOCHEMISTRY; MAJOR HISTOCOMPATIBILITY COMPLEX; MOLECULAR DYNAMICS; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEOMICS; RECEPTOR DOWN REGULATION; STOMACH CARCINOMA; STOMACH LYMPHOMA; STOMACH MUCOSA; WESTERN BLOTTING;

HEPATITIS C VIRUS;

EID: 53549122224     PISSN: 18628346     EISSN: None     Source Type: Journal    
DOI: 10.1002/prca.200800059     Document Type: Article

References (48)

1. De Re, V., Caggiari, L., Simula, M. P., De Vita, S. et al., B-cell Iymphomas associated with HCV infection. Gastroenterology 2007, 132, 1205-1207.
2. Sansonno, D., Carbone, A., De Re, V., Dammacco, F., Hepatitis C virus infection, cryoglobulinaemia, and beyond. Rheumatology 2007, 46, 572-578.
3. Bartenschlager, R., Lohmann, V., Replication of hepatitis C virus. J. Gen. Virol. 2000, 81, 1631-1648.
4. Bartenschlager, R., Sparacio, S., Hepatitis C virus molecular clones and their replication capacity in vivo and in cell culture. Virus Res. 2007, 127, 195-207.
5. Fang, C., Yi, Z., Liu, F., Lan, S., Wang, J. et al., Proteome analysis of human liver carcinoma Huh7 cells harboring hepatitis C virus subgenomic replicon. Proteomics 2006, 6, 519-527.
6. Tang, W., Lázaro, C. A., Campbell, J. S., Parks, W. T. et al., Responses of non-transformed human hepatocytes to conditional expression of full-length hepatitis C virus open reading frame. Am. J. Pathol. 2007, 171, 1831-1846.
7. Maki, A., Kono, H., Gupta, M., Asakawa, M. et al., Predictive power of biomarkers of oxidative stress and inflammation in patients with hepatitis C virus-associated hepatocellular carcinoma. Ann. Surg. Oncol. 2007, 14, 1182-1190.
8. Abdalla, M. Y., Ahmad, I. M., Spitz, D. R., Schmidt, W. N., Britigan, B. E., Hepatitis C virus-core and non structural proteins lead to different effects on cellular antioxidant defenses. J. Med. Virol. 2005, 76, 489-497.
9. Ghaziani, T., Shan, Y., Lambrecht, R. W., Donahue, S. E. et al., HCV proteins increase expression of heme oxygenase-1 (HO-1) and decrease expression of Bach1 in human hepatoma cells. J. Hepatol. 2006, 45, 5-12.
10. Thoren, F., Romero, A., Lindh, M., Dahlgren, C., Hellstrand, K., A hepatitis C virus-encoded, nonstructural protein (NS3) triggers dysfunction and apoptosis in lymphocytes: Role of NADPH oxidase-derived oxygen radicals. J. Leukoc. Biol. 2004, 76, 1180-1186.
11. Moriishi, K., Mochizuki, R., Moriya, K., Miyamoto, H. et al., Critical role of PA28gamma in hepatitis C virus-associated steatogenesis and hepatocarcinogenesis. Proc. Natl. Acad. Sci. USA 2007, 104, 1661-1666.
12. Takeshita, M., Sakai, H., Okamura, S., Higaki, K. et al., Prevalence of hepatitis C virus infection in cases of B-cell lymphoma in Japan. Histopathology 2006, 48, 189-198.
13. Visco, C., Arcaini, L., Brusamolino, E., Burcheri, S. et al., Distinctive natural history in hepatitis C virus positive diffuse large B-cell lymphoma: analysis of 156 patients from northern Italy. Ann. Oncol. 2006, 17, 1434-1440.
14. De Vita, S., De Re, V., Sansonno, D., Sorrentino, D. et al., Gastric mucosa as an additional extrahepatic localization of hepatitis C virus: Viral detection in gastric low-grade lymphoma associated with autoimmune disease and in chronic gastritis. Hepatology 2000, 31, 182-189.
15. Sansonno, D., Cornacchiulo, V., Iacobelli, A. R., Di Stefano, R. et al., Localization of hepatitis C virus antigens in liver and skin tissues of chronic hepatitis C virus-infected patients with mixed cryoglobulinemia. Hepatology 1995, 21, 305-312.
16. De Re, V., Simula, M. P., Caggiari, L., Orzes, N. et al., Proteins specifically hyperexpressed in a coeliac disease patient with aberrant T cells. Clin. Exp. Immunol. 2007, 148, 402-409.
17. De Re, V., Sansonno, D., Simula, M. P., Caggiari, L. et al., HCV-NS3 and IgG-Fc crossreactive IgM in patients with type II mixed cryoglobulinemia and B-cell clonal proliferations. Leukemia 2006, 20, 1145-1154.
18. Gong, G., Waris, G., Tanveer, R., Siddiqui, A., Human hepatitis C virus NS5A protein alters intracellular calcium levels, induces oxidative stress, and activates STAT-3 and NF-kappa B. Proc. Natl. Acad. Sci. USA 2001, 98, 9599-9604.
19. Tardif, K. D., Siddiqui, A., Cell surface expression of major histocompatibility complex class I molecules is reduced in hepatitis C virus subgenomic replicon-expressing cells. J. Virol. 2003, 77, 11644-11650.
20. Mori, K., Tripartite management of unfolded proteins in the endoplasmic reticulum. Cell 2000, 101, 451-454.
21. Rao, R. V., Niazi, K., Mollahan, P., Mao, X. et al., Coupling endoplasmic reticulum stress to the cell-death program: A novel HSP90-independent role for the small chaperone protein p23. Cell Death Differ. 2006, 13, 415-425.
22. Verma, R., Chen, S., Feldman, R., Schieltz, D. et al., Proteasomal proteomics: Identification of nucleotide-sensitive proteasome-interacting proteins by mass spectrometric analysis of affinity-purified proteasomes. Mol. Biol. Cell 2000, 11, 3425-3439.
23. +T cells. Nat. Immunol. 2007, 6, 593-599.
24. Kunisawa, J., Shastri, N., The group II chaperonin TRiC protects proteolytic intermediates from degradation in the MHC class I antigen processing pathway. Mol. Cell 2003, 12, 565-576.
25. Srivastava, P. K., Menoret, A., Basu, S., Binder, R. J., McQuade, K. L., Heat shock proteins come of age: primitive functions acquire new roles in an adaptive world. Immunity 1998, 8, 657-665.
26. Garbi, N., Tanaka, S., Momburg, F., Hämmerling, G. J., Impaired assembly of the major histocompatibility complex class I peptide-loading complex in mice deficient in the oxidoreductase ERp57. Nat. Immunol. 2006, 7, 93-102.
27. Benali-Furet, N. L., Chami, M., Houel, L., De Giorgi, F. et al., Hepatitis C virus core triggers apoptosis in liver cells by inducing ER stress and ER calcium depletion. Oncogene 2005, 24, 4921-4933.
28. Piccoli, C., Scrima, R., Quarato, G., D'Aprile, A. et al., Hepatitis C virus protein expression causes calcium-mediated mitochondrial bioenergetic dysfunction and nitro-oxidative stress. Hepatology 2007, 46, 58-65.
29. Korenaga, M., Wang, T., Li, Y., Showalter, L. A. et al., Hepatitis C virus core protein inhibits mitochondrial electron transport and increases reactive oxygen species (ROS) production. J. Biol. Chem. 2005, 280, 37481-37488.
30. Neumann, C. A., Krause, D. S., Carman, C. V., Das, S. et al., Essential role for the peroxiredoxin Prdx1 in erythrocyte antioxidant defence and tumour suppression. Nature 2003, 424, 561-565.
31. Walsh-Reitz, M. M., Huang, E. F., Musch, M. W., Chang, E. B. et al., AMP-18 protects barrier function of colonic epithelial cells: role of tight junction proteins. Am. J. Physiol. Gastrointest. Liver Physiol. 2005, 289, G163-G171
32. Yoshida, H., ER stress and diseases. FEBS J. 2007, 274, 630-658.
33. Castelli, C., Rivoltini, L., Rini, F., Belli, F. et al., Heat shock proteins: Biological functions and clinical application as personalized vaccines for human cancer. Cancer Immunol. Immunother. 2004, 53, 227-233.
34. Srivastava, P., Interaction of heat shock proteins with peptides and antigen presenting cells: chaperoning of the innate and adaptive immune responses. Annu. Rev. Immunol. 2002, 20, 395-425.
35. Seliger, B., Ritz, U., Ferrone, S., Molecular mechanisms of HLA class I antigen abnormalities following viral infection and transformation. Int. J. Cancer 2006, 118, 129-138.
36. Chignard, N., Shang, S., Wang, H., Marrero, J. et al., Cleavage of endoplasmic reticulum proteins in hepatocellular carcinoma: Detection of generated fragments in patient sera. Gastroenterology 2006, 130, 2010-2022.
37. Klaunig, J. E., Kamendulis, L. M., The role of oxidative stress in carcinogenesis. Annu. Rev. Pharmacol. Toxicol. 2004, 44, 239-267.
38. Mehta, K., Van Thiel, D. H., Shah, N., Mobarhan, S., Non-alcoholic fatty liver disease: Pathogenesis and the role of antioxidants. Nutr. Rev. 2002, 60, 289-293
39. Okuda, M., Li, K., Beard, M. R., Showalter, L. A. et al., Mitochondrial injury, oxidative stress, and antioxidant gene expression are induced by hepatitis C virus core protein. Gastroenterology 2002, 122, 366-375.
40. Jain, S. K., Pemberton, P. W., Smith, A., McMahon, R. F. et al., Oxidative stress in chronic hepatitis C: Not just a feature of late stage disease. J. Hepatol. 2002, 36, 805-811.
41. Li, Y., Boehning, D. F., Qian, T., Popov, V. L., Weinman, S. A., Hepatitis C virus core protein increases mitochondrial ROS production by stimulation of Ca2+ uniporter activity. FASEB J. 2007, 21, 2474-2485.
42. Ohashi, Y., Kaneko, S. J., Cupples, T. E., Young, S. R., Ubiquinol cytochrome c reductase (UQCRFS1) gene amplification in primary breast cancer core biopsy samples. Gynecol. Oncol. 2004, 93, 54-58.
43. Kaneko, S. J., Gerasimova, T., Smith, S. T., Lloyd, K. O. et al., CA125 and UQCRFS1 FISH studies of ovarian carcinoma. Gynecol. Oncol. 2003, 90, 29-36.
44. Smedby, K. E., Baecklund, E., Askling, J., Malignant lymphomas in autoimmunity and inflammation: A review of risks, risk factors, and lymphoma characteristics. Cancer Epidemiol. Biomarkers Prev. 2006, 15, 2069-2077.
45. Sagaert, X., Wolf-Peeters, C., Noels, H., Baens, M., The pathogenesis of MALT lymphomas: Where do we stand? Leukemia 2007, 21, 389-396.
46. Engels, E. A., Infectious agents as causes of non-Hodgkin lymphoma. Cancer Epidemiol. Biomarkers Prev. 2007, 16, 401-404.
47. Polyak, S. J., Morishima, C., Shuhart, M. C., Wang, C. C. et al., Inhibition of T-cell inflammatory cytokines, hepatocyte NF-kappaB signaling, and HCV infection by standardized Silymarin. Gastroenterology 2007, 132, 1925-1936.
48. Kroemer, G., Galluzzi, L., Brenner, C., Mitochondrial membrane permeabilization in cell death. Physiol. Rev. 2007, 87, 99-163.