Cell Surface Expression of Major Histocompatibility Complex Class I Molecules Is Reduced in Hepatitis C Virus Subgenomic Replicon-Expressing Cells

Journal of Virology

Volumn 77, Issue 21, 2003, Pages 11644-11650

  Tardif, Keith D ^a   Siddiqui, Aleem ^a  

^a UNIVERSITY OF COLORADO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1;

ANTIGEN EXPRESSION; ANTIGEN PRESENTATION; ARTICLE; CELL SURFACE; CHRONIC HEPATITIS; CONTROLLED STUDY; CYTOTOXIC T LYMPHOCYTE; ENDOPLASMIC RETICULUM; GENE DISRUPTION; HEPATITIS C VIRUS; HUMAN; HUMAN CELL; IMMUNE RESPONSE; MAJOR HISTOCOMPATIBILITY COMPLEX; PRIORITY JOURNAL; PROTEIN ASSEMBLY; PROTEIN EXPRESSION; PROTEIN FOLDING; PROTEIN GLYCOSYLATION; REPLICON; STRESS; VIRUS GENE; VIRUS INFECTION; VIRUS PATHOGENESIS;

ENDOPLASMIC RETICULUM; GENE EXPRESSION REGULATION; GENES, MHC CLASS I; GENOME, VIRAL; GLYCOSYLATION; HEPACIVIRUS; HISTOCOMPATIBILITY ANTIGENS CLASS I; HUMANS; PROTEIN FOLDING; REPLICON; TUMOR CELLS, CULTURED; VIRUS REPLICATION;

EID: 0142124130     PISSN: 0022538X     EISSN: None     Source Type: Journal    
DOI: 10.1128/JVI.77.21.11644-11650.2003     Document Type: Article

References (45)

1. Ahn, K., A. Angulo, P. Ghazal, P. A. Peterson, Y. Yang, and K. Fruh. 1996. human cytomegalovirus inhibits antigen presentation by a sequential multistep process. Proc. Natl. Acad. Sci. USA 93:10990-10995.
2. Ahn, K., T. H. Meyer, S. Uebel, P. Sempe, H. Djaballah, Y. Yang, P. A. Peterson, K. Fruh, and R. Tampe. 1996. Molecular mechanism and species specificity of TAP inhibition by herpes simplex virus ICP47. EMBO J. 15:3247-3255.
3. Ahn, K., A. Gruhler, B. Galocha, T. R. Jones, E. J. Wiertz, H. L. Ploegh, P. A. Peterson, Y. Yang, and K. Fruh. 1997. The ER-luminal domain of the HCMV glycoprotein US6 inhibits peptide translocation by TAP. Immunity 6:613-621.
4. Andersson, M., S. Paabo, T. Nilsson, and P. A Peterson. 1985. Impaired intracellular transport of class I MHC antigens as a possible means for adenoviruses to evade immune surveillance. Cell 43:215-222.
5. Barnstable, C. J., W. F. Bodmer, G. Brown, G. Galfre, C. Milstein, A. F. Williams, and A. Ziegler. 1978. Production of monoclonal antibodies to group A erythrocytes, HLA and other human cell surface antigens: new tools for genetic analysis. Cell 14:9-20.
6. Bartenschlager, R., and V. Lohmann. 2000. Replication of hepatitis C virus. J. Gen. Virol. 81:1631-1648.
7. Bonifacino, J. S., and A. M. Weissman. 1998. Ubiquitin and the control of protein fate in the secretory and endocytic pathways. Annu. Rev. Cell Dev. Biol. 14:19-57.
8. Burgert, H.-G., and S. Kvist. 1985. An adenovirus type 2 glycoprotein blocks cell surface expression of human histocompatibility class I antigens. Cell 41:987-997.
9. Carreno, B. M., K. L. Schreiber, D. J. McKean, I. Stroynowski, and T. H. Hansen. 1995. Aglycosylated and phosphatidylinositol-anchored MHC class I molecules are associated with calnexin. J. Immunol. 154:5173-5180.
10. Cerny, A., and F. V. Chisari. 1999. Pathogenesis of chronic hepatitis C: immunological features of hepatic injury and viral persistence. Hepatology 30:595-601.
11. Degen, E., M. F. Cohen-Doyle, and D. B. Williams. 1992. Efficient dissociation of the p88 chaperone from major histocompatibility complex class I molecules requires both beta 2-microglobulin and peptide. J. Exp. Med. 175:1653-1661.
12. Deleersnyder, V., A. Pillez, C. Wychowski, K. Blight, J. Xu, Y. S. Hahn, C. M. Rice, and J. Dubisson. 1997. Formation of native hepatitis C virus glycoprotein complexes. J. Virol. 71:697-704.
13. Di Biscegli, A. M. 1997. Hepatitis C and hepatocellular carcinoma. Hepatology 26:34S-38S.
14. Fearon, D. T., and R. M. Locksley. 1996. The instructive role of innate immunity in the acquired immune response. Science 272:50-53.
15. Gilbert, M. J., S. R. Riddell, B. Plachter, and P. D. Greenberg. 1996. Cytomegalovirus selectively blocks antigen processing and presentation of its immediate-early gene product. Nature 383:720-722.
16. Gong, G., G. Waris, R. Tanveer, and A. Siddiqui. 2001. Human hepatitis C virus NS5A protein alters intracellular calcium levels, induces oxidative stress, and activates STAT-3 and NF-κB. Proc. Natl. Acad. Sci. USA 98:9599-9604.
17. Guo, J. T., V. V. Bichko, and C. Seeger. 2001. Effect of alpha interferon on the hepatitis C virus replication. J. Virol. 75:8516-8523.
18. Hijikata, M., H. Mizushima, Y. Tanji, Y. Komoda, Y. Hirowatari, T. Akagi, N. Kato, K. Kimura, and K. Shimotohno. 1993. Proteolytic processing and membrane association of putative nonstructural proteins of hepatitis C virus. Proc. Natl. Acad. Sci. USA 90:10773-10777.
19. Hill, A., P. Jugovic, I. York, G. Russ, J. Bennink, J. Yewdell, H. Ploegh, and D. Johnson. 1995. Herpes simplex virus turns off the TAP to evade host immunity. Nature 375:411-415.
20. Hudson, A. W., P. M. Howley, and H. L. Ploegh. 2001. A human herpesvirus 7 glycoprotein, U21, diverts major histocompatibility complex class I molecules to lysosomes. J. Virol. 75:12347-12358.
21. Jones, T. R., E. J. Wiertz, L. Sun, K. N. Fish, J. A. Nelson, and H. L. Ploegh. 1996. Human cytomegalovirus US3 impairs transport and maturation of major histocompatibility complex class I heavy chains. Proc. Natl. Acad. Sci. USA 93:11327-11333.
22. Kleneman, P., M. Lucas, E. Barnes, and G. Harcourt. 2002. Immunity to hepatitis C virus: stunned but not defeated. Microbes Infect. 4:57-65.
23. Kolykhalov, A. A., K. Mihalik, S. M. Feinstone, and C. M. Rice. 2000. Hepatitis C virus-encoded enzymatic activities and conserved RNA elements in the 3′ nontranslated region are essential for virus replication in vivo. J. Virol. 74:2046-2051.
24. +-T-cell responses against hepatitis C virus reveals multiple unpredicted specificities. J. Virol. 76:6104-6113.
25. Lefebvre, S., P. Moreau, J. Dausset, E. D. Carosella, and P. Paul. 1999. Downregulation of HLA class I gene transcription in choriocarcinoma cells is controlled by the proximal promoter element and can be reversed by CIITA. Placenta 20:293-301.
26. Liberman, E., Y.-L. Fong, M. J. Selby, Q.-L. Choo, L. Cousens, M. Houghton, and T. S. B. Yen. 1999. Activation of the grp78 and grp94 promoters by hepatitis C virus E2 envelope protein. J. Virol. 73:3718-3722.
27. Lohmann, V., F. Korner, J.-O. Koch, U. Herian, L. Theilmann, and R. Bartenschlager. 1999. Replication of subgenomic hepatitis C virus RNAs in a hepatoma cell line. Science 285:110-113.
28. Mansky, P., W. M. Brown, J. H. Park, J. W. Choi, and S. Y. Yang. 1994. The secondary kB element, kB2, of the HLA-A class I regulatory element is an essential part of the promoter. J. Immunol. 153:5082-5090.
29. Moradpour, D., P. Kary, C. M. Rice, and H. E. Blum. 1998. Continuous human cell lines inducibly expressing hepatitis C virus structural and nonstructural proteins. Hepatology 28:192-201.
30. Mori, K. 2000. Tripartite management of unfolded proteins in the endoplasmic reticulum. Cell 101:451-454.
31. Noessner, E., and P. Parham. 1995. Species-specific differences in chaperone interaction of human and mouse major histocompatibility complex class I molecules. J. Exp. Med. 181:327-337.
32. Owen, M. J., A. M. Kissonerghis, and H. F. Lodish. 1980. Biosynthesis of HLA-A and HLA-B antigens in vivo. J. Biol. Chem. 255:9678-9684.
33. Pahl, H. L., M. Sester, H.-G. Burgert, and P. A. Baeuerle. 1996. Activation of transcription factor NF-κB by adenovirus E3/19K requires ER retention. J. Cell Biol. 132:511-522.
34. Parham, P. 1996. Functions for MHC class I carbohydrates inside and outside the cell. Trends Biochem. Sci. 21:427-433.
35. Rajagopalan, S., and M. B. Brenner. 1994. Calnexin retains unassembled major histocompatibility complex class I free heavy chains in the endoplasmic reticulum. J. Exp. Med. 180:407-412.
36. Reed, K. E., and C. M. Rice. 2000. Overview of hepatitis C virus genome structure, polyprotein processing, and protein properties. Curr. Top. Microbiol. Immunol. 242:55-84.
37. Riemann, D., A. Kehlen, and J. Langner. 1999. CD13 - not just a marker in leukemia typing. Immunol. Today 20:83-88.
38. Rijibrand, R., and S. Lemon. 1999. Internal ribosome entry site-mediated translation in hepatitis C virus replication. Curr. Top. Microbiol. Immunol. 242:86-116.
39. Schoneich, J., J. L. Lee, P. Mansky, M. Sheffery, and S. Y. Yang. 1997. The pentanucleotide ATTGG, the "inverted CCAAT, " is an essential element for HLA class I gene transcription. J. Immunol. 158:4788-4796.
40. Shamu, C. E., C. M. Story, T. A. Rapoport, and H. L. Ploegh. 1999. The pathway of US11-dependent degradation of MHC class I heavy chains involves a ubiquitin-conjugated intermediate. J. Cell Biol. 147:45-57.
41. Tardif, K. D., K. Mori, and A. Siddiqui. 2002. Hepatitis C virus subgenomic replicons induce endoplasmic reticulum stress activating an intracellular signaling pathway. J. Virol. 76:7453-7459.
42. Tortorella, D., B. E. Gewurz, M. H. Furman, D. J. Schust, and H. L. Ploegh. 2000. Viral subversion of the immune system. Annu. Rev. Immunol. 18:861-926.
43. Tsukiyama-Kohara, K., N. Iizuka, M. Kohara, and A. Nomoto. 1992. Internal ribosome entry site within hepatitis C virus RNA. J. Virol. 66:1476-1483.
44. Wang, C., P. Sarnow, and A. Siddiqui. 1993. Translation of human hepatitis C virus RNA in cultured cells is mediated by an internal ribosome-binding mechanism. J. Virol. 67:3338-3344.
45. Wiertz, E. J., T. R. Jones, L. Sun, M. Bogyo, H. J. Geuze, and H. L. Ploegh. 1996. The human cytomegalovirus US11 gene product dislocates MHC I heavy chains from the endoplasmic reticulum to the cytosol. Cell 84:769-779.