-
1
-
-
14844331501
-
Molecular motors and mechanisms of directional transport in neurons
-
Hirokawa, N. & Takemura, R. Molecular motors and mechanisms of directional transport in neurons. Nat. Rev. Neurosci. 6, 201-214 (2005).
-
(2005)
Nat. Rev. Neurosci
, vol.6
, pp. 201-214
-
-
Hirokawa, N.1
Takemura, R.2
-
2
-
-
0038380203
-
Processive and nonprocessive models of kinesin movement
-
Endow, S.A. & Barker, D.S. Processive and nonprocessive models of kinesin movement. Annu. Rev. Physiol. 65, 161-175 (2003).
-
(2003)
Annu. Rev. Physiol
, vol.65
, pp. 161-175
-
-
Endow, S.A.1
Barker, D.S.2
-
3
-
-
3242776257
-
The kinetic mechanism of kinesin
-
Cross, R.A. The kinetic mechanism of kinesin. Trends Biochem. Sci. 29, 301-309 (2004).
-
(2004)
Trends Biochem. Sci
, vol.29
, pp. 301-309
-
-
Cross, R.A.1
-
4
-
-
34247571461
-
Kinesin motor mechanics: Binding, stepping, tracking, gating, and limping
-
Block, S.M. Kinesin motor mechanics: binding, stepping, tracking, gating, and limping. Biophys. J. 92, 2986-2995 (2007).
-
(2007)
Biophys. J
, vol.92
, pp. 2986-2995
-
-
Block, S.M.1
-
5
-
-
50349090965
-
Intracellular transport and kinesin superfamily proteins, KIFs: Structure, function, and dynamics
-
Hirokawa, N. & Noda, Y. Intracellular transport and kinesin superfamily proteins, KIFs: structure, function, and dynamics. Physiol. Rev. 88, 1089-1118 (2008).
-
(2008)
Physiol. Rev
, vol.88
, pp. 1089-1118
-
-
Hirokawa, N.1
Noda, Y.2
-
6
-
-
1542353988
-
Kinesin ATPase: Rate-limiting ADP release
-
Hackney, D.D. Kinesin ATPase: rate-limiting ADP release. Proc. Natl. Acad. Sci. USA 85, 6314-6318 (1988).
-
(1988)
Proc. Natl. Acad. Sci. USA
, vol.85
, pp. 6314-6318
-
-
Hackney, D.D.1
-
7
-
-
0028985886
-
Pathway of processive ATP hydrolysis by kinesin
-
Gilbert, S.P., Webb, M.R., Brune, M. & Johnson, K.A. Pathway of processive ATP hydrolysis by kinesin. Nature 373, 671-676 (1995).
-
(1995)
Nature
, vol.373
, pp. 671-676
-
-
Gilbert, S.P.1
Webb, M.R.2
Brune, M.3
Johnson, K.A.4
-
8
-
-
0027405349
-
Recombinant kinesin motor domain binds to β-tubulin and decorates microtubules with a B surface lattice
-
Song, Y.H. & Mandelkow, E. Recombinant kinesin motor domain binds to β-tubulin and decorates microtubules with a B surface lattice. Proc. Natl. Acad. Sci. USA 90, 1671-1675 (1993).
-
(1993)
Proc. Natl. Acad. Sci. USA
, vol.90
, pp. 1671-1675
-
-
Song, Y.H.1
Mandelkow, E.2
-
9
-
-
0027407526
-
Decoration of the microtubule surface by one kinesin head per tubulin heterodimer
-
Harrison, B.C. et al. Decoration of the microtubule surface by one kinesin head per tubulin heterodimer. Nature 362, 73-75 (1993).
-
(1993)
Nature
, vol.362
, pp. 73-75
-
-
Harrison, B.C.1
-
10
-
-
0022981422
-
Bovine brain kinesin is a microtubule-activated ATPase
-
Kuznetsov, S.A. & Gelfand, V.I. Bovine brain kinesin is a microtubule-activated ATPase. Proc. Natl. Acad. Sci. USA 83, 8530-8534 (1986).
-
(1986)
Proc. Natl. Acad. Sci. USA
, vol.83
, pp. 8530-8534
-
-
Kuznetsov, S.A.1
Gelfand, V.I.2
-
11
-
-
0024195951
-
Comparative analysis of tubulin sequences
-
Little, M. & Seehaus, T. Comparative analysis of tubulin sequences. Comp. Biochem. Physiol. B 90, 655-670 (1988).
-
(1988)
Comp. Biochem. Physiol. B
, vol.90
, pp. 655-670
-
-
Little, M.1
Seehaus, T.2
-
12
-
-
33646494080
-
Structural mechanisms underlying nucleotide-dependent self-assembly of tubulin and its relatives
-
Nogales, E. & Wang, H.W. Structural mechanisms underlying nucleotide-dependent self-assembly of tubulin and its relatives. Curr. Opin. Struct. Biol. 16, 221-229 (2006).
-
(2006)
Curr. Opin. Struct. Biol
, vol.16
, pp. 221-229
-
-
Nogales, E.1
Wang, H.W.2
-
13
-
-
0028200793
-
Evidence for alternating head catalysis by kinesin during microtubule-stimulated ATP hydrolysis
-
Hackney, D.D. Evidence for alternating head catalysis by kinesin during microtubule-stimulated ATP hydrolysis. Proc. Natl. Acad. Sci. USA 91, 6865-6869 (1994).
-
(1994)
Proc. Natl. Acad. Sci. USA
, vol.91
, pp. 6865-6869
-
-
Hackney, D.D.1
-
14
-
-
0034306462
-
Force production by single kinesin motors
-
Schnitzer, M.J., Visscher, K. & Block, S.M. Force production by single kinesin motors. Nat. Cell Biol. 2, 718-723 (2000).
-
(2000)
Nat. Cell Biol
, vol.2
, pp. 718-723
-
-
Schnitzer, M.J.1
Visscher, K.2
Block, S.M.3
-
15
-
-
0041522803
-
Processivity of the single-headed kinesin KIF1A through biased binding to tubulin
-
Okada, Y., Higuchi, H. & Hirokawa, N. Processivity of the single-headed kinesin KIF1A through biased binding to tubulin. Nature 424, 574-577 (2003).
-
(2003)
Nature
, vol.424
, pp. 574-577
-
-
Okada, Y.1
Higuchi, H.2
Hirokawa, N.3
-
16
-
-
0038381479
-
Stepping and stretching. How kinesin uses internal strain to walk processively
-
Rosenfeld, S.S., Fordyce, P.M., Jefferson, G.M., King, P.H. & Block, S.M. Stepping and stretching. How kinesin uses internal strain to walk processively. J. Biol. Chem. 278, 18550-18556 (2003).
-
(2003)
J. Biol. Chem
, vol.278
, pp. 18550-18556
-
-
Rosenfeld, S.S.1
Fordyce, P.M.2
Jefferson, G.M.3
King, P.H.4
Block, S.M.5
-
17
-
-
1542618337
-
Kinesin's second step
-
Klumpp, L.M., Hoenger, A. & Gilbert, S.P. Kinesin's second step. Proc. Natl. Acad. Sci. USA 101, 3444-3449 (2004).
-
(2004)
Proc. Natl. Acad. Sci. USA
, vol.101
, pp. 3444-3449
-
-
Klumpp, L.M.1
Hoenger, A.2
Gilbert, S.P.3
-
18
-
-
0033576727
-
A structural change in the kinesin motor protein that drives motility
-
Rice, S. et al. A structural change in the kinesin motor protein that drives motility. Nature 402, 778-784 (1999).
-
(1999)
Nature
, vol.402
, pp. 778-784
-
-
Rice, S.1
-
19
-
-
0343415156
-
The way things move: Looking under the hood of molecular motor proteins
-
Vale, R.D. & Milligan, R.A. The way things move: looking under the hood of molecular motor proteins. Science 288, 88-95 (2000).
-
(2000)
Science
, vol.288
, pp. 88-95
-
-
Vale, R.D.1
Milligan, R.A.2
-
20
-
-
0030267349
-
Switches, latches, and amplifiers: Common themes of G proteins and molecular motors
-
Vale, R.D. Switches, latches, and amplifiers: common themes of G proteins and molecular motors. J. Cell Biol. 135, 291-302 (1996).
-
(1996)
J. Cell Biol
, vol.135
, pp. 291-302
-
-
Vale, R.D.1
-
21
-
-
0032515955
-
Interaction of mant-adenosine nucleotides and magnesium with kinesin
-
Cheng, J.Q., Jiang, W. & Hackney, D.D. Interaction of mant-adenosine nucleotides and magnesium with kinesin. Biochemistry 37, 5288-5295 (1998).
-
(1998)
Biochemistry
, vol.37
, pp. 5288-5295
-
-
Cheng, J.Q.1
Jiang, W.2
Hackney, D.D.3
-
22
-
-
0034242456
-
Regulation of cellular magnesium
-
Romani, A.M. & Scarpa, A. Regulation of cellular magnesium. Front. Biosci. 5, D720-D734 (2000).
-
(2000)
Front. Biosci
, vol.5
-
-
Romani, A.M.1
Scarpa, A.2
-
23
-
-
0034682668
-
2+ cofactor in the guanine nucleotide exchange and GTP hydrolysis reactions of Rho family GTP-binding proteins
-
2+ cofactor in the guanine nucleotide exchange and GTP hydrolysis reactions of Rho family GTP-binding proteins. J. Biol. Chem. 275, 25299-25307 (2000).
-
(2000)
J. Biol. Chem
, vol.275
, pp. 25299-25307
-
-
Zhang, B.1
Zhang, Y.2
Wang, Z.3
Zheng, Y.4
-
24
-
-
14044268874
-
Magnesium regulates ADP dissociation from myosin V
-
Rosenfeld, S.S., Houdusse, A. & Sweeney, H.L. Magnesium regulates ADP dissociation from myosin V. J. Biol. Chem. 280, 6072-6079 (2005).
-
(2005)
J. Biol. Chem
, vol.280
, pp. 6072-6079
-
-
Rosenfeld, S.S.1
Houdusse, A.2
Sweeney, H.L.3
-
25
-
-
0035834388
-
The guanine nucleotide-binding switch in three dimensions
-
Vetter, I.R. & Wittinghofer, A. The guanine nucleotide-binding switch in three dimensions. Science 294, 1299-1304 (2001).
-
(2001)
Science
, vol.294
, pp. 1299-1304
-
-
Vetter, I.R.1
Wittinghofer, A.2
-
26
-
-
0942279704
-
Structural elements, mechanism, and evolutionary convergence of Rho protein-guanine nucleotide exchange factor complexes
-
Erickson, J.W. & Cerione, R.A. Structural elements, mechanism, and evolutionary convergence of Rho protein-guanine nucleotide exchange factor complexes. Biochemistry 43, 837-842 (2004).
-
(2004)
Biochemistry
, vol.43
, pp. 837-842
-
-
Erickson, J.W.1
Cerione, R.A.2
-
27
-
-
13444252631
-
-
Rossman, K.L., Der, C.J. & Sondek, J. GEF means go: turning on RHO GTPases with guanine nucleotide-exchange factors. Nat. Rev. Mol. Cell Biol. 6, 167-180 (2005).
-
Rossman, K.L., Der, C.J. & Sondek, J. GEF means go: turning on RHO GTPases with guanine nucleotide-exchange factors. Nat. Rev. Mol. Cell Biol. 6, 167-180 (2005).
-
-
-
-
28
-
-
0040241932
-
The structure of the nucleotide-binding site of kinesin
-
Muller, J., Marx, A., Sack, S., Song, Y.H. & Mandelkow, E. The structure of the nucleotide-binding site of kinesin. Biol. Chem. 380, 981-992 (1999).
-
(1999)
Biol. Chem
, vol.380
, pp. 981-992
-
-
Muller, J.1
Marx, A.2
Sack, S.3
Song, Y.H.4
Mandelkow, E.5
-
29
-
-
0035942761
-
Switch-based mechanism of kinesin motors
-
Kikkawa, M. et al. Switch-based mechanism of kinesin motors. Nature 411, 439-445 (2001).
-
(2001)
Nature
, vol.411
, pp. 439-445
-
-
Kikkawa, M.1
-
30
-
-
3442876110
-
KIF1A alternately uses two loops to bind microtubules
-
Nitta, R., Kikkawa, M., Okada, Y. & Hirokawa, N. KIF1A alternately uses two loops to bind microtubules. Science 305, 678-683 (2004).
-
(2004)
Science
, vol.305
, pp. 678-683
-
-
Nitta, R.1
Kikkawa, M.2
Okada, Y.3
Hirokawa, N.4
-
31
-
-
0035355208
-
A structural pathway for activation of the kinesin motor ATPase
-
Yun, M., Zhang, X., Park, C.G., Park, H.W. & Endow, S.A. A structural pathway for activation of the kinesin motor ATPase. EMBO J. 20, 2611-2618 (2001).
-
(2001)
EMBO J
, vol.20
, pp. 2611-2618
-
-
Yun, M.1
Zhang, X.2
Park, C.G.3
Park, H.W.4
Endow, S.A.5
-
32
-
-
34248200882
-
The beginning of kinesin's force-generating cycle visualized at 9- resolution
-
Sindelar, C.V. & Downing, K.H. The beginning of kinesin's force-generating cycle visualized at 9- resolution. J. Cell Biol. 177, 377-385 (2007).
-
(2007)
J. Cell Biol
, vol.177
, pp. 377-385
-
-
Sindelar, C.V.1
Downing, K.H.2
-
33
-
-
0035834521
-
Refined structure of αβ-tubulin at 3.5 Å resolution
-
Lowe, J., Li, H., Downing, K.H. & Nogales, E. Refined structure of αβ-tubulin at 3.5 Å resolution. J. Mol. Biol. 313, 1045-1057 (2001).
-
(2001)
J. Mol. Biol
, vol.313
, pp. 1045-1057
-
-
Lowe, J.1
Li, H.2
Downing, K.H.3
Nogales, E.4
-
34
-
-
0034695259
-
15 A° resolution model of the monomeric kinesin motor, KIF1A
-
Kikkawa, M., Okada, Y. & Hirokawa, N. 15 A° resolution model of the monomeric kinesin motor, KIF1A. Cell 100, 241-252 (2000).
-
(2000)
Cell
, vol.100
, pp. 241-252
-
-
Kikkawa, M.1
Okada, Y.2
Hirokawa, N.3
-
35
-
-
33748931452
-
High-resolution cryo-EM maps show the nucleotide binding pocket of KIF1A in open and closed conformations
-
Kikkawa, M. & Hirokawa, N. High-resolution cryo-EM maps show the nucleotide binding pocket of KIF1A in open and closed conformations. EMBO J. 25, 4187-4194 (2006).
-
(2006)
EMBO J
, vol.25
, pp. 4187-4194
-
-
Kikkawa, M.1
Hirokawa, N.2
-
36
-
-
1342296567
-
A common mechanism for microtubule destabilizers-M type kinesins stabilize curling of the protofilament using the class-specific neck and loops
-
Ogawa, T., Nitta, R., Okada, Y. & Hirokawa, N. A common mechanism for microtubule destabilizers-M type kinesins stabilize curling of the protofilament using the class-specific neck and loops. Cell 116, 591-602 (2004).
-
(2004)
Cell
, vol.116
, pp. 591-602
-
-
Ogawa, T.1
Nitta, R.2
Okada, Y.3
Hirokawa, N.4
-
37
-
-
33748421625
-
Large conformational changes in a kinesin motor catalyzed by interaction with microtubules
-
Hirose, K., Akimaru, E., Akiba, T., Endow, S.A. & Amos, L.A. Large conformational changes in a kinesin motor catalyzed by interaction with microtubules. Mol. Cell 23, 913-923 (2006).
-
(2006)
Mol. Cell
, vol.23
, pp. 913-923
-
-
Hirose, K.1
Akimaru, E.2
Akiba, T.3
Endow, S.A.4
Amos, L.A.5
-
38
-
-
33745839637
-
Feedback of the kinesin-1 neck-linker position on the catalytic site
-
Hahlen, K. et al. Feedback of the kinesin-1 neck-linker position on the catalytic site. J. Biol. Chem. 281, 18868-18877 (2006).
-
(2006)
J. Biol. Chem
, vol.281
, pp. 18868-18877
-
-
Hahlen, K.1
-
39
-
-
0034628619
-
Role of the kinesin neck linker and catalytic core in microtubule-based motility
-
Case, R.B., Rice, S., Hart, C.L., Ly, B. & Vale, R.D. Role of the kinesin neck linker and catalytic core in microtubule-based motility. Curr. Biol. 10, 157-160 (2000).
-
(2000)
Curr. Biol
, vol.10
, pp. 157-160
-
-
Case, R.B.1
Rice, S.2
Hart, C.L.3
Ly, B.4
Vale, R.D.5
-
40
-
-
37548999364
-
Force generation in kinesin hinges on cover-neck bundle formation
-
Hwang, W., Lang, M.J. & Karplus, M. Force generation in kinesin hinges on cover-neck bundle formation. Structure 16, 62-71 (2008).
-
(2008)
Structure
, vol.16
, pp. 62-71
-
-
Hwang, W.1
Lang, M.J.2
Karplus, M.3
-
41
-
-
0032491432
-
Engineering a lever into the kinesin neck
-
Mazumdar, M. & Cross, R.A. Engineering a lever into the kinesin neck. J. Biol. Chem. 273, 29352-29359 (1998).
-
(1998)
J. Biol. Chem
, vol.273
, pp. 29352-29359
-
-
Mazumdar, M.1
Cross, R.A.2
-
42
-
-
0036150882
-
Kinesin: Switch I & II and the motor mechanism
-
Kull, F.J. & Endow, S.A. Kinesin: switch I & II and the motor mechanism. J. Cell Sci. 115, 15-23 (2002).
-
(2002)
J. Cell Sci
, vol.115
, pp. 15-23
-
-
Kull, F.J.1
Endow, S.A.2
-
43
-
-
0033539520
-
Kinesin's processivity results from mechanical and chemical coordination between the ATP hydrolysis cycles of the two motor domains
-
Hancock, W.O. & Howard, J. Kinesin's processivity results from mechanical and chemical coordination between the ATP hydrolysis cycles of the two motor domains. Proc. Natl. Acad. Sci. USA 96, 13147-13152 (1999).
-
(1999)
Proc. Natl. Acad. Sci. USA
, vol.96
, pp. 13147-13152
-
-
Hancock, W.O.1
Howard, J.2
-
44
-
-
0842263751
-
What kinesin does at roadblocks: The coordination mechanism for molecular walking
-
Crevel, I.M. et al. What kinesin does at roadblocks: the coordination mechanism for molecular walking. EMBO J. 23, 23-32 (2004).
-
(2004)
EMBO J
, vol.23
, pp. 23-32
-
-
Crevel, I.M.1
-
45
-
-
0842277818
-
Inhibition of kinesin motility by ADP and phosphate supports a hand-over-hand mechanism
-
Schief, W.R., Clark, R.H., Crevenna, A.H. & Howard, J. Inhibition of kinesin motility by ADP and phosphate supports a hand-over-hand mechanism. Proc. Natl. Acad. Sci. USA 101, 1183-1188 (2004).
-
(2004)
Proc. Natl. Acad. Sci. USA
, vol.101
, pp. 1183-1188
-
-
Schief, W.R.1
Clark, R.H.2
Crevenna, A.H.3
Howard, J.4
-
46
-
-
34147188510
-
An ATP gate controls tubulin binding by the tethered head of kinesin-1
-
Alonso, M.C. et al. An ATP gate controls tubulin binding by the tethered head of kinesin-1. Science 316, 120-123 (2007).
-
(2007)
Science
, vol.316
, pp. 120-123
-
-
Alonso, M.C.1
-
47
-
-
0031059866
-
Processing of X-ray diffraction data collected in oscillation mode
-
Otwinowski, Z. & Minor, W. Processing of X-ray diffraction data collected in oscillation mode. Methods Enzymol. 276, 307-326 (1997).
-
(1997)
Methods Enzymol
, vol.276
, pp. 307-326
-
-
Otwinowski, Z.1
Minor, W.2
-
48
-
-
3543012707
-
Crystallography & NMR system: A new software suite for macromolecular structure determination
-
Brunger, A.T. et al. Crystallography & NMR system: a new software suite for macromolecular structure determination. Acta Crystallogr. D Biol. Crystallogr. 54, 905-921 (1998).
-
(1998)
Acta Crystallogr. D Biol. Crystallogr
, vol.54
, pp. 905-921
-
-
Brunger, A.T.1
-
49
-
-
0033582814
-
A processive single-headed motor: Kinesin superfamily protein KIF1A
-
Okada, Y. & Hirokawa, N. A processive single-headed motor: kinesin superfamily protein KIF1A. Science 283, 1152-1157 (1999).
-
(1999)
Science
, vol.283
, pp. 1152-1157
-
-
Okada, Y.1
Hirokawa, N.2
-
50
-
-
1642317185
-
Some precautions in using chelators to buffer metals in biological solutions
-
Patton, C., Thompson, S. & Epel, D. Some precautions in using chelators to buffer metals in biological solutions. Cell Calcium 35, 427-431 (2004).
-
(2004)
Cell Calcium
, vol.35
, pp. 427-431
-
-
Patton, C.1
Thompson, S.2
Epel, D.3
-
51
-
-
0028865659
-
Mechanism of microtubule kinesin ATPase
-
Ma, Y.Z. & Taylor, E.W. Mechanism of microtubule kinesin ATPase. Biochemistry 34, 13242-13251 (1995).
-
(1995)
Biochemistry
, vol.34
, pp. 13242-13251
-
-
Ma, Y.Z.1
Taylor, E.W.2
|