A Common Mechanism for Microtubule Destabilizers - M Type Kinesins Stabilize Curling of the Protofilament Using the Class-Specific Neck and Loops

Cell

Volumn 116, Issue 4, 2004, Pages 591-602

  Ogawa, Tadayuki ^a   Nitta, Ryo ^a   Okada, Yasushi ^a   Hirokawa, Nobutaka ^a  

^a UNIVERSITY OF TOKYO   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

KINESIN; PROTEIN KIF2C; PROTEIN SUBUNIT; TUBULIN; UNCLASSIFIED DRUG;

AMINO TERMINAL SEQUENCE; ANIMAL CELL; ARTICLE; BINDING AFFINITY; CONFORMATION; CONTROLLED STUDY; MICROTUBULE; MOLECULAR MECHANICS; MUTATIONAL ANALYSIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN DOMAIN; PROTEIN FAMILY; PROTEIN FUNCTION; PROTEIN STRUCTURE; RIGIDITY; X RAY CRYSTALLOGRAPHY;

ANIMALIA; MURINAE;

EID: 1342296567     PISSN: 00928674     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0092-8674(04)00129-1     Document Type: Article

References (42)

1. Aizawa H., Sekine Y., Takemura R., Zhang Z., Nangaku M., Hirokawa N. Kinesin family in murine central nervous system. J. Cell Biol. 119:1992;1287-1296.
2. Brunger A.T., Adams P.D., Clore G.M., DeLano W.L., Gros P., Grosse Kunstleve R.W., Jiang J.S., Kuszewski J., Nilges M., Pannu N.S., et al. Crystallography & NMR system. A new software suite for macromolecular structure determination Acta Crystallogr. D Biol. Crystallogr. 54:1998;905-921.
3. Case R.B., Pierce D.W., Hom Booher N., Hart C.L., Vale R.D. The directional preference of kinesin motors is specified by an element outside of the motor catalytic domain. Cell. 90:1997;959-966.
4. Dagenbach E.M., Endow S.A. A new kinesin tree. J. Cell Sci. 117:2004;3-7.
5. Desai A., Verma S., Mitchison T.J., Walczak C.E. Kin I kinesins are microtubule-destabilizing enzymes. Cell. 96:1999;69-78.
6. Endow S.A., Kang S.J., Satterwhite L.L., Rose M.D., Skeen V.P., Salmon E.D. Yeast Kar3 is a minus-end microtubule motor protein that destabilizes microtubules preferentially at the minus ends. EMBO J. 13:1994;2708-2713.
7. Endow S.A., Higuchi H. A mutant of the motor protein kinesin that moves in both directions on microtubules. Nature. 406:2000;913-916.
8. Gigant B., Curmi P.A., Martin Barbey C., Charbaut E., Lachkar S., Lebeau L., Siavoshian S., Sobel A., Knossow M. The 4 A X-ray structure of a tubulin:stathmin-like domain complex. Cell. 102:2000;809-816.
9. Henningsen U., Schliwa M. Reversal in the direction of movement of a molecular motor. Nature. 389:1997;93-96.
10. Hirokawa N. Organelle transport along microtubule - the role of KIFs (kinesin superfamily proteins). Trends Cell Biol. 132:1996;667-679.
11. Hirokawa N. Kinesin and dynein superfamily proteins and the mechanism of organelle transport. Science. 279:1998;519-526.
12. Hirokawa N., Noda Y., Okada Y. Kinesin and dynein superfamily proteins in organelle transport and cell division. Curr. Opin. Cell. Biol. 10:1998;60-73.
13. Homma N., Takei Y., Tanaka Y., Nakata T., Terada S., Kikkawa M., Noda Y., Hirokawa N. Kinesin superfamily protein 2A (KIF2A) functions in suppression of collateral branch extension. Cell. 114:2003;229-239.
14. Hunter A.W., Caplow M., Coy D.L., Hancock W.O., Diez S., Wordeman L., Howard J. The kinesin-related protein MCAK is a microtubule depolymerase that forms an ATP-hydrolyzing complex at microtubule ends. Mol. Cell. 11:2003;445-457.
15. Inoue Y., Toyoshima Y.Y., Iwane A.H., Morimoto S., Higuchi H., Yanagida T. Movements of truncated kinesin fragments with a short or an artificial flexible neck. Proc. Natl. Acad. Sci. USA. 94:1997;7275-7280.
16. Jiang W., Stock M.F., Li X., Hackney D.D. Influence of the kinesin neck domain on dimerization and ATPase kinetics. J. Biol. Chem. 272:1997;7626-7632.
17. Kikkawa M., Sablin E.P., Okada Y., Yajima H., Fletterick R.J., Hirokawa N. Switch-based mechanism of kinesin motors. Nature. 411:2001;439-445.
18. Kim A.J., Endow S.A. A kinesin family tree. J. Cell Sci. 113:2000;3681-3682.
19. Maney T., Wagenbach M., Wordeman L. Molecular dissection of the microtubule depolymerizing activity of mitotic centromere-associated kinesin. J. Biol. Chem. 276:2001;34753-34758.
20. Miki H., Setou M., Kaneshiro K., Hirokawa N. All kinesin superfamily protein, KIF, genes in mouse and human. Proc. Natl. Acad. Sci. USA. 98:2001;7004-7011.
21. Miki H., Setou M., Hirokawa N., Group R.I.K.E.N.G.E.R., Members G.S.L. Kinesin superfamily proteins (KIFs) in the mouse transcriptome. Genome Res. 13:2003;1455-1465.
22. Moores C.A., Yu M., Guo J., Beraud C., Sakowicz R., Milligan R.A. A mechanism for microtubule depolymerization by KinI kinesins. Mol. Cell. 9:2002;903-909.
23. Moores C.A., Hekmat-Nejad M., Sakowicz R., Milligan R.A. Regulation of KinI kinesin ATPase activity by binding to the microtubule lattice. J. Cell Biol. 163:2003;963-971.
24. Muller Reichert T., Chretien D., Severin F., Hyman A.A. Structural changes at microtubule ends accompanying GTP hydrolysis. information from a slowly hydrolyzable analogue of GTP, guanylyl (alpha,beta) methylenediphosphonate Proc. Natl. Acad. Sci. USA. 95:1998;3661-3666.
25. Niederstrasser H., Salehi Had H., Gan E.C., Walczak C., Nogales E. XKCM1 acts on a single protofilament and requires the C terminus of tubulin. J. Mol. Biol. 316:2002;817-828.
26. Noda Y., Sato Yoshitake R., Kondo S., Nangaku M., Hirokawa N. KIF2 is a new microtubule-based anterograde motor that transports membranous organelles distinct from those carried by kinesin heavy chain or KIF3A/B. J. Cell Biol. 129:1995;157-167.
27. Okada Y., Hirokawa N. Mechanism of the single-headed processivity. diffusional anchoring between the K-loop of kinesin and the C terminus of tubulin Proc. Natl. Acad. Sci. USA. 97:2000;640-645.
28. Okada Y., Higuchi H., Hirokawa N. Processivity of the single-headed kinesin KIF1A through biased binding to tubulin. Nature. 424:2003;574-577.
29. Otwinowski Z., Minor W. Processing of X-ray diffraction data collected in oscillation mode. Methods Enzymol. 276:1997;307-326.
30. Ovechkina Y., Wagenbach M., Wordeman L. K-loop insertion restores microtubule depolymerizing activity of a "neckless" MCAK mutant. J. Cell Biol. 159:2002;557-562.
31. Rice S., Lin A.W., Safer D., Hart C.L., Naber N., Carragher B.O., Cain S.M., Pechatnikova E., Wilson Kubalek E.M., Whittaker M., et al. A structural change in the kinesin motor protein that drives motility. Nature. 402:1999;778-784.
32. Sablin E.P., Case R.B., Dai S.C., Hart C.L., Ruby A., Vale R.D., Fletterick R.J. Direction determination in the minus-end-directed kinesin motor ncd. Nature. 395:1998;813-816.
33. Saito N., Okada Y., Noda Y., Kinoshita Y., Kondo S., Hirokawa N. KIFC2 is a novel neuron-specific C-terminal type kinesin superfamily motor for dendritic transport of multivesicular body-like organelles. Neuron. 18:1997;425-438.
34. Skiniotis G., Surrey T., Altmann S., Gross H., Song Y.H., Mandelkow E., Hoenger A. Nucleotide-induced conformations in the neck region of dimeric kinesin. EMBO J. 22:2003;1518-1528.
35. Takemura R., Okabe S., Umeyama T., Kanai Y., Cowan N.J., Hirokawa N. Increased microtubule stability and alpha tubulin acetylation in cells transfected with microtubule-associated proteins MAP1B, MAP2 or tau. J. Cell Sci. 103:1992;953-964.
36. Vale R.D., Fletterick R.J. The design plan of kinesin motors. Ann. Rev. Cell Dev. Biol. 13:1997;745-777.
37. Walczak C.E., Mitchison T.J., Desai A. XKCM1. a xenopus kinesin-related protein that regulates microtubule dynamics during mitotic spindle assembly Cell. 84:1996;37-47.
38. Watts N.R., Sackett D.L., Ward R.D., Miller M.W., Wingfield P.T., Stahl S.S., Steven A.C. HIV-1 rev depolymerizes microtubules to form stable bilayered rings. J. Cell Biol. 150:2000;349-360.
39. Wendt T.G., Volkmann N., Skiniotis G., Goldie K.N., Muller J., Mandelkow E., Hoenger A. Microscopic evidence for a minus-end-directed power stroke in the kinesin motor ncd. EMBO J. 21:2002;5969-5978.
40. Wordeman L., Mitchison T.J. Identification and partial characterization of mitotic centromere-associated kinesin, a kinesin-related protein that associates with centromeres during mitosis. J. Cell Biol. 128:1995;95-104.
41. Yun M., Zhang X., Park C.G., Park H.W., Endow S.A. A structural pathway for activation of the kinesin motor ATPase. EMBO J. 20:2001;2611-2618.
42. Yun M., Bronner C.E., Park C.G., Cha S.S., Park H.W., Endow S.A. Rotation of the stalk/neck and one head in a new crystal structure of the kinesin motor protein, Ncd. EMBO J. 22:2003;5382-5389.