-
1
-
-
34247621784
-
Molecular pathogenesis of inflammatory bowel disease: Genotypes, phenotypes and personalized medicine
-
Goyette P, Labbé C, Trinh TT, Xavier RJ, Rioux JD: Molecular pathogenesis of inflammatory bowel disease: genotypes, phenotypes and personalized medicine. Ann Med 2007, 39:177-199
-
(2007)
Ann Med
, vol.39
, pp. 177-199
-
-
Goyette, P.1
Labbé, C.2
Trinh, T.T.3
Xavier, R.J.4
Rioux, J.D.5
-
2
-
-
2442585704
-
Functional variants of OCTN cation transporter genes are associated with Crohn disease
-
Peltekova VD, Wintle RF, Rubin LA, Amos CI, Huang Q, Gu X, Newman B, Van Oene M, Cescon D, Greenberg G, Griffiths AM, St George-Hyslop PH, Siminovitch KA: Functional variants of OCTN cation transporter genes are associated with Crohn disease. Nat Genet 2004, 36:471-475
-
(2004)
Nat Genet
, vol.36
, pp. 471-475
-
-
Peltekova, V.D.1
Wintle, R.F.2
Rubin, L.A.3
Amos, C.I.4
Huang, Q.5
Gu, X.6
Newman, B.7
Van Oene, M.8
Cescon, D.9
Greenberg, G.10
Griffiths, A.M.11
St George-Hyslop, P.H.12
Siminovitch, K.A.13
-
3
-
-
2442519456
-
Genetic variation in DLG5 is associated with inflammatory bowel disease
-
Stoll M, Corneliussen B, Costello CM, Waetzig GH, Mellgard B, Koch WA, Rosenstiel P, Albrecht M, Croucher PJ, Seegert D, Nikolaus S, Hampe J, Lengauer T, Pierrou S, Foelsch UR, Mathew CG, Lagerstrom-Fermer M, Schreiber S: Genetic variation in DLG5 is associated with inflammatory bowel disease. Nat Genet 2004, 36:476-480
-
(2004)
Nat Genet
, vol.36
, pp. 476-480
-
-
Stoll, M.1
Corneliussen, B.2
Costello, C.M.3
Waetzig, G.H.4
Mellgard, B.5
Koch, W.A.6
Rosenstiel, P.7
Albrecht, M.8
Croucher, P.J.9
Seegert, D.10
Nikolaus, S.11
Hampe, J.12
Lengauer, T.13
Pierrou, S.14
Foelsch, U.R.15
Mathew, C.G.16
Lagerstrom-Fermer, M.17
Schreiber, S.18
-
4
-
-
0033605292
-
Signaling by the germinal center kinase family of protein kinases
-
Kyriakis JM: Signaling by the germinal center kinase family of protein kinases. J Biol Chem 1999, 274:5259-5262
-
(1999)
J Biol Chem
, vol.274
, pp. 5259-5262
-
-
Kyriakis, J.M.1
-
5
-
-
0032928614
-
Mitogen-activated protein kinase: Conservation of a three-kinase module from yeast to human
-
Widmann C, Gibson S, Jarpe MB, Johnson GL: Mitogen-activated protein kinase: conservation of a three-kinase module from yeast to human. Physiol Rev 1999, 79:143-180
-
(1999)
Physiol Rev
, vol.79
, pp. 143-180
-
-
Widmann, C.1
Gibson, S.2
Jarpe, M.B.3
Johnson, G.L.4
-
6
-
-
0029814060
-
Activation of a human Ste20-like kinase by oxidant stress defines a novel stress response pathway
-
Pombo CM, Bonventre JV, Molnar A, Kyriakis J, Force T: Activation of a human Ste20-like kinase by oxidant stress defines a novel stress response pathway. EMBO J 1996, 15:4537-4546
-
(1996)
EMBO J
, vol.15
, pp. 4537-4546
-
-
Pombo, C.M.1
Bonventre, J.V.2
Molnar, A.3
Kyriakis, J.4
Force, T.5
-
7
-
-
0033954866
-
Deficiency of a STE20/PAK family kinase LOK leads to the acceleration of LFA-1 clustering and cell adhesion of activated lymphocytes
-
Endo J, Toyama-Sorimachi N, Taya C, Kuramochi-Miyagawa S, Nagata K, Kuida K, Takashi T, Yonekawa H, Yoshizawa Y, Miyasaka N, Karasuyama H: Deficiency of a STE20/PAK family kinase LOK leads to the acceleration of LFA-1 clustering and cell adhesion of activated lymphocytes. FEBS Lett 2000, 468:234-238
-
(2000)
FEBS Lett
, vol.468
, pp. 234-238
-
-
Endo, J.1
Toyama-Sorimachi, N.2
Taya, C.3
Kuramochi-Miyagawa, S.4
Nagata, K.5
Kuida, K.6
Takashi, T.7
Yonekawa, H.8
Yoshizawa, Y.9
Miyasaka, N.10
Karasuyama, H.11
-
8
-
-
0037020101
-
Stk10, a new member of the polo-like kinase kinase family highly expressed in hematopoietic tissue
-
Wagner S, Flood TA, O'Reilly P, Hume K, Sabourin LA: Stk10, a new member of the polo-like kinase kinase family highly expressed in hematopoietic tissue. J Biol Chem 2002, 277:37685-37692
-
(2002)
J Biol Chem
, vol.277
, pp. 37685-37692
-
-
Wagner, S.1
Flood, T.A.2
O'Reilly, P.3
Hume, K.4
Sabourin, L.A.5
-
9
-
-
34250353521
-
Induction of vascular permeability: Beta PIX and GIT1 scaffold the activation of extracellular signal-regulated kinase by PAK
-
Stockton R, Reutershan J, Scott D, Sanders J, Ley K, Schwartz MA: Induction of vascular permeability: beta PIX and GIT1 scaffold the activation of extracellular signal-regulated kinase by PAK. Mol Biol Cell 2007, 18:2346-2355
-
(2007)
Mol Biol Cell
, vol.18
, pp. 2346-2355
-
-
Stockton, R.1
Reutershan, J.2
Scott, D.3
Sanders, J.4
Ley, K.5
Schwartz, M.A.6
-
10
-
-
0034738962
-
SPAK, a STE20/SPS1-related kinase that activates the p38 pathway
-
Johnston AM, Naselli G, Gonez LJ, Martin RM, Harrison LC, DeAizpurua HJ: SPAK, a STE20/SPS1-related kinase that activates the p38 pathway. Oncogene 2000, 19:4290-4297
-
(2000)
Oncogene
, vol.19
, pp. 4290-4297
-
-
Johnston, A.M.1
Naselli, G.2
Gonez, L.J.3
Martin, R.M.4
Harrison, L.C.5
DeAizpurua, H.J.6
-
11
-
-
33847374563
-
Cloning and characterization of a new intestinal inflammation-associated colonic epithelial Ste20-related protein kinase isoform
-
Yan Y, Nguyen H, Dalmasso G, Sitaraman SV, Merlin D: Cloning and characterization of a new intestinal inflammation-associated colonic epithelial Ste20-related protein kinase isoform. Biochim Biophys Acta 2007, 1769:106-116
-
(2007)
Biochim Biophys Acta
, vol.1769
, pp. 106-116
-
-
Yan, Y.1
Nguyen, H.2
Dalmasso, G.3
Sitaraman, S.V.4
Merlin, D.5
-
12
-
-
0035341895
-
The Ste20 group kinases as regulators of MAP kinase cascades
-
Dan I, Watanabe NM, Kusumi A: The Ste20 group kinases as regulators of MAP kinase cascades. Trends Cell Biol 2001, 11:220-230
-
(2001)
Trends Cell Biol
, vol.11
, pp. 220-230
-
-
Dan, I.1
Watanabe, N.M.2
Kusumi, A.3
-
13
-
-
1842524184
-
SPAK kinase is a substrate and target of PKCtheta in T-cell receptor-induced AP-1 activation pathway
-
Li Y, Hu J, Vita R, Sun B, Tabata H, Altman A: SPAK kinase is a substrate and target of PKCtheta in T-cell receptor-induced AP-1 activation pathway. EMBO J 2004, 23:1112-1122
-
(2004)
EMBO J
, vol.23
, pp. 1112-1122
-
-
Li, Y.1
Hu, J.2
Vita, R.3
Sun, B.4
Tabata, H.5
Altman, A.6
-
14
-
-
0037184942
-
Cation chloride cotransporters interact with the stress-related kinases Ste20-related proline-alanine-rich kinase (SPAK) and oxidative stress response 1 (OSR1)
-
Piechotta K, Lu J, Delpire E: Cation chloride cotransporters interact with the stress-related kinases Ste20-related proline-alanine-rich kinase (SPAK) and oxidative stress response 1 (OSR1). J Biol Chem 2002, 277:50812-50819
-
(2002)
J Biol Chem
, vol.277
, pp. 50812-50819
-
-
Piechotta, K.1
Lu, J.2
Delpire, E.3
-
15
-
-
0042847432
-
PASK (proline-alanine-rich STE20-related kinase), a regulatory kinase of the Na-K-Cl cotransporter (NKCC1)
-
Dowd BF, Forbush B: PASK (proline-alanine-rich STE20-related kinase), a regulatory kinase of the Na-K-Cl cotransporter (NKCC1). J Biol Chem 2003, 278:27347-27353
-
(2003)
J Biol Chem
, vol.278
, pp. 27347-27353
-
-
Dowd, B.F.1
Forbush, B.2
-
16
-
-
30644472724
-
Characterization of SPAK and OSR1, regulatory kinases of the Na-K-2Cl cotransporter
-
Gagnon KB, England R, Delpire E: Characterization of SPAK and OSR1, regulatory kinases of the Na-K-2Cl cotransporter. Mol Cell Biol 2006, 26:689-698
-
(2006)
Mol Cell Biol
, vol.26
, pp. 689-698
-
-
Gagnon, K.B.1
England, R.2
Delpire, E.3
-
17
-
-
0031008850
-
Expression of the bumetanide-sensitive Na-K-Cl cotransporter BSC2 is differentially regulated by fluid mechanical and inflammatory cytokine stimuli in vascular endothelium
-
Topper JN, Wasserman SM, Anderson KR, Cai J, Falb D, Gimbrone Jr MA: Expression of the bumetanide-sensitive Na-K-Cl cotransporter BSC2 is differentially regulated by fluid mechanical and inflammatory cytokine stimuli in vascular endothelium. J Clin Invest 1997, 99:2941-2949
-
(1997)
J Clin Invest
, vol.99
, pp. 2941-2949
-
-
Topper, J.N.1
Wasserman, S.M.2
Anderson, K.R.3
Cai, J.4
Falb, D.5
Gimbrone Jr, M.A.6
-
18
-
-
34250370467
-
Mice lacking NKCC1 is protected from development of bacteremia and hypothermic sepsis secondary to bacterial pneumonia
-
Nguyen M, Pace AJ, Koller BH: Mice lacking NKCC1 is protected from development of bacteremia and hypothermic sepsis secondary to bacterial pneumonia. J Exp Med 2007, 204:1383-1393
-
(2007)
J Exp Med
, vol.204
, pp. 1383-1393
-
-
Nguyen, M.1
Pace, A.J.2
Koller, B.H.3
-
19
-
-
0031032680
-
Functional role of a conformationally flexible homopurine/homopyrimidine domain of the androgen receptor gene promoter interacting with Sp1 and a pyrimidine single strand DNA-binding protein
-
Chen S, Supakar PC, Vellanoweth RL, Song CS, Chatterjee B, Roy AK: Functional role of a conformationally flexible homopurine/homopyrimidine domain of the androgen receptor gene promoter interacting with Sp1 and a pyrimidine single strand DNA-binding protein. Mol Endocrinol 1997, 11:3-15
-
(1997)
Mol Endocrinol
, vol.11
, pp. 3-15
-
-
Chen, S.1
Supakar, P.C.2
Vellanoweth, R.L.3
Song, C.S.4
Chatterjee, B.5
Roy, A.K.6
-
20
-
-
0031803059
-
SB 203580 inhibits p38 mitogen-activated protein kinase, nitric oxide production, and inducible nitric oxide synthase in bovine cartilage-derived chondrocytes
-
Badger AM, Cook MN, Lark MW, Newman-Tarr TM, Swift BA, Nelson AH, Barone FC, Kumar S: SB 203580 inhibits p38 mitogen-activated protein kinase, nitric oxide production, and inducible nitric oxide synthase in bovine cartilage-derived chondrocytes. J Immunol 1998, 161:467-473
-
(1998)
J Immunol
, vol.161
, pp. 467-473
-
-
Badger, A.M.1
Cook, M.N.2
Lark, M.W.3
Newman-Tarr, T.M.4
Swift, B.A.5
Nelson, A.H.6
Barone, F.C.7
Kumar, S.8
-
21
-
-
0032193226
-
p38 MAPK is required for CD40-induced gene expression and proliferation in B lymphocytes
-
Craxton A, Shu G, Graves JD, Saklatvala J, Krebs EG, Clark EA: p38 MAPK is required for CD40-induced gene expression and proliferation in B lymphocytes. J Immunol 1998, 161:3225-3236
-
(1998)
J Immunol
, vol.161
, pp. 3225-3236
-
-
Craxton, A.1
Shu, G.2
Graves, J.D.3
Saklatvala, J.4
Krebs, E.G.5
Clark, E.A.6
-
22
-
-
9444228220
-
Inhibition of p38 MAP kinase- and RICK/NF-kappaB-signaling suppresses inflammatory bowel disease
-
Hollenbach E, Neumann M, Vieth M, Roessner A, Malfertheiner P, Naumann M: Inhibition of p38 MAP kinase- and RICK/NF-kappaB-signaling suppresses inflammatory bowel disease. FASEB J 2004, 18:1550-1552
-
(2004)
FASEB J
, vol.18
, pp. 1550-1552
-
-
Hollenbach, E.1
Neumann, M.2
Vieth, M.3
Roessner, A.4
Malfertheiner, P.5
Naumann, M.6
-
23
-
-
0021823570
-
Short-term stimulation of lipogenesis by triiodothyronine in maintenance cultures of rat hepatocytes
-
Gnoni GV, Geelen MJ, Bijleveld C, Quagliariello E, van den Bergh SG: Short-term stimulation of lipogenesis by triiodothyronine in maintenance cultures of rat hepatocytes. Biochem Biophys Res Commun 1985, 128:525-530
-
(1985)
Biochem Biophys Res Commun
, vol.128
, pp. 525-530
-
-
Gnoni, G.V.1
Geelen, M.J.2
Bijleveld, C.3
Quagliariello, E.4
van den Bergh, S.G.5
-
24
-
-
0018909468
-
Ribonucleic acid synthesis in embryonic chick muscle, rates of synthesis and half-lives of transfer and ribosomal RNA species
-
Nwagwu M, Nana M: Ribonucleic acid synthesis in embryonic chick muscle, rates of synthesis and half-lives of transfer and ribosomal RNA species. J Embryol Exp Morphol 1980, 56:253-267
-
(1980)
J Embryol Exp Morphol
, vol.56
, pp. 253-267
-
-
Nwagwu, M.1
Nana, M.2
-
25
-
-
33750573521
-
Molecular diagnosis of Beckwith-Wiedemann syndrome using quantitative methylation-sensitive polymerase chain reaction
-
Coffee B, Muralidharan K, Highsmith Jr WE, Lapunzina P, Warren ST: Molecular diagnosis of Beckwith-Wiedemann syndrome using quantitative methylation-sensitive polymerase chain reaction. Genet Med 2006, 8:628-634
-
(2006)
Genet Med
, vol.8
, pp. 628-634
-
-
Coffee, B.1
Muralidharan, K.2
Highsmith Jr, W.E.3
Lapunzina, P.4
Warren, S.T.5
-
26
-
-
0031736096
-
Chronic experimental colitis induced by dextran sulphate sodium (DSS) is characterized by Th1 and Th2 cytokines
-
Dieleman LA, Palmen MJ, Akol H, Bloemena E, Peña AS, Meuwissen SG, Van Rees EP: Chronic experimental colitis induced by dextran sulphate sodium (DSS) is characterized by Th1 and Th2 cytokines. Clin Exp Immunol 1998, 114:385-391
-
(1998)
Clin Exp Immunol
, vol.114
, pp. 385-391
-
-
Dieleman, L.A.1
Palmen, M.J.2
Akol, H.3
Bloemena, E.4
Peña, A.S.5
Meuwissen, S.G.6
Van Rees, E.P.7
-
27
-
-
0037043658
-
Inflammatory bowel disease
-
Podolsky DK: Inflammatory bowel disease. N Engl J Med 2002, 347:417-429
-
(2002)
N Engl J Med
, vol.347
, pp. 417-429
-
-
Podolsky, D.K.1
-
28
-
-
0033103805
-
Impaired on/off regulation of TNF biosynthesis in mice lacking TNF AU-rich elements: Implications for joint and gut-associated immunopathologies
-
Kontoyiannis D, Pasparakis M, Pizarro TT, Cominelli F, Kollias G: Impaired on/off regulation of TNF biosynthesis in mice lacking TNF AU-rich elements: implications for joint and gut-associated immunopathologies. Immunity 1999, 10:387-398
-
(1999)
Immunity
, vol.10
, pp. 387-398
-
-
Kontoyiannis, D.1
Pasparakis, M.2
Pizarro, T.T.3
Cominelli, F.4
Kollias, G.5
-
29
-
-
0030954732
-
A short-term study of chimeric monoclonal antibody cA2 to tumor necrosis factor alpha for Crohn's disease. Crohn's Disease cA2 Study Group
-
Targan SR, Hanauer SB, van Deventer SJ, Mayer L, Present DH, Braakman T, DeWoody KL, Schaible TF, Rutgeerts PJ: A short-term study of chimeric monoclonal antibody cA2 to tumor necrosis factor alpha for Crohn's disease. Crohn's Disease cA2 Study Group. N Engl J Med 1997, 337:1029-1035
-
(1997)
N Engl J Med
, vol.337
, pp. 1029-1035
-
-
Targan, S.R.1
Hanauer, S.B.2
van Deventer, S.J.3
Mayer, L.4
Present, D.H.5
Braakman, T.6
DeWoody, K.L.7
Schaible, T.F.8
Rutgeerts, P.J.9
-
30
-
-
0034994026
-
TNF-α down-regulates murine hepatic growth hormone receptor expression by inhibiting Sp1 and Sp3 binding
-
Denson LA, Menon RK, Shaufl A, Bajwa HS, Williams CR, Karpen SJ: TNF-α down-regulates murine hepatic growth hormone receptor expression by inhibiting Sp1 and Sp3 binding. J Clin Invest 2001, 107:1451-1458
-
(2001)
J Clin Invest
, vol.107
, pp. 1451-1458
-
-
Denson, L.A.1
Menon, R.K.2
Shaufl, A.3
Bajwa, H.S.4
Williams, C.R.5
Karpen, S.J.6
-
31
-
-
0028104109
-
Sp1 elements protect a CpG island from de novo methylation
-
Brandeis M, Frank D, Keshet I, Siegfried Z, Mendelsohn M, Nemes A, Temper V, Razin A, Cedar H: Sp1 elements protect a CpG island from de novo methylation. Nature 1994, 371:435-438
-
(1994)
Nature
, vol.371
, pp. 435-438
-
-
Brandeis, M.1
Frank, D.2
Keshet, I.3
Siegfried, Z.4
Mendelsohn, M.5
Nemes, A.6
Temper, V.7
Razin, A.8
Cedar, H.9
-
32
-
-
0027960055
-
Sp1 sites in the mouse aprt gene promoter are required to prevent methylation of the CpG island
-
Macleod D, Charlton J, Mullins J, Bird AP: Sp1 sites in the mouse aprt gene promoter are required to prevent methylation of the CpG island. Genes Dev 1994, 8:2282-2292
-
(1994)
Genes Dev
, vol.8
, pp. 2282-2292
-
-
Macleod, D.1
Charlton, J.2
Mullins, J.3
Bird, A.P.4
-
33
-
-
0035021811
-
Identification and characterization of the potential promoter regions of 1031 kinds of human genes
-
Suzuki Y, Tsunoda T, Sese J, Taira H, Mizushima-Sugano J, Hata H, Ota T, Isogai T, Tanaka T, Nakamura Y, Suyama A, Sakaki Y, Morishita S, Okubo K, Sugano S: Identification and characterization of the potential promoter regions of 1031 kinds of human genes. Genome Res 2001, 11:677-684
-
(2001)
Genome Res
, vol.11
, pp. 677-684
-
-
Suzuki, Y.1
Tsunoda, T.2
Sese, J.3
Taira, H.4
Mizushima-Sugano, J.5
Hata, H.6
Ota, T.7
Isogai, T.8
Tanaka, T.9
Nakamura, Y.10
Suyama, A.11
Sakaki, Y.12
Morishita, S.13
Okubo, K.14
Sugano, S.15
-
34
-
-
0035929642
-
The hepatitis B virus X protein induces HIV-1 replication and transcription in synergy with T-cell activation signals: Functional roles of NF-kappaB/NF-AT and SP1-binding sites in the HIV-1 long terminal repeat promoter
-
Gómez-Gonzalo M, Carretero M, Rullas J, Lara-Pezzi E, Aramburu J, Berkhout B, Alcamí J, López-Cabrera M: The hepatitis B virus X protein induces HIV-1 replication and transcription in synergy with T-cell activation signals: functional roles of NF-kappaB/NF-AT and SP1-binding sites in the HIV-1 long terminal repeat promoter. J Biol Chem 2001, 276:35435-35443
-
(2001)
J Biol Chem
, vol.276
, pp. 35435-35443
-
-
Gómez-Gonzalo, M.1
Carretero, M.2
Rullas, J.3
Lara-Pezzi, E.4
Aramburu, J.5
Berkhout, B.6
Alcamí, J.7
López-Cabrera, M.8
-
35
-
-
33750426515
-
5′ Long terminal repeat (LTR)-selective methylation of latently infected HIV-1 provirus that is demethylated by reactivation signals
-
Ishida T, Hamano A, Koiwa T, Watanabe T: 5′ Long terminal repeat (LTR)-selective methylation of latently infected HIV-1 provirus that is demethylated by reactivation signals. Retrovirology 2006, 3:69-75
-
(2006)
Retrovirology
, vol.3
, pp. 69-75
-
-
Ishida, T.1
Hamano, A.2
Koiwa, T.3
Watanabe, T.4
-
36
-
-
34547106324
-
Tumor necrosis factor alpha (TNFalpha) stimulates Map4k4 expression through TNFalpha receptor 1 signaling to c-Jun and activating transcription factor 2
-
Tesz GJ, Guilherme A, Guntur KV, Hubbard AC, Tang X, Chawla A, Czech MP: Tumor necrosis factor alpha (TNFalpha) stimulates Map4k4 expression through TNFalpha receptor 1 signaling to c-Jun and activating transcription factor 2. J Biol Chem 2007, 282:19302-19312
-
(2007)
J Biol Chem
, vol.282
, pp. 19302-19312
-
-
Tesz, G.J.1
Guilherme, A.2
Guntur, K.V.3
Hubbard, A.C.4
Tang, X.5
Chawla, A.6
Czech, M.P.7
-
37
-
-
33846214719
-
Prevalence of the initiator over the TATA box in human and yeast genes and identification of DNA motifs enriched in human TATAless core promoters
-
Yang C, Bolotin E, Jiang T, Sladek FM, Martinez E: Prevalence of the initiator over the TATA box in human and yeast genes and identification of DNA motifs enriched in human TATAless core promoters. Gene 2007, 389:52-65
-
(2007)
Gene
, vol.389
, pp. 52-65
-
-
Yang, C.1
Bolotin, E.2
Jiang, T.3
Sladek, F.M.4
Martinez, E.5
-
38
-
-
0027966011
-
In vitro transcription of the TATAA-less mouse thymidylate synthase promoter: Multiple transcription start points and evidence for bidirectionality
-
Liao WC, Geng Y, Johnson LF: In vitro transcription of the TATAA-less mouse thymidylate synthase promoter: multiple transcription start points and evidence for bidirectionality. Gene 1994, 146:183-189
-
(1994)
Gene
, vol.146
, pp. 183-189
-
-
Liao, W.C.1
Geng, Y.2
Johnson, L.F.3
-
39
-
-
0020529697
-
Isolation of transcription factors that discriminate between different promoters recognized by RNA polymerase II
-
Dynan WS, Tjian R: Isolation of transcription factors that discriminate between different promoters recognized by RNA polymerase II. Cell 1983, 32:669-680
-
(1983)
Cell
, vol.32
, pp. 669-680
-
-
Dynan, W.S.1
Tjian, R.2
-
40
-
-
0023007801
-
Purification and biochemical characterization of the promoter-specific transcription factor, Sp1
-
Briggs MR, Kadanoga JT, Bell SP, Tjian R: Purification and biochemical characterization of the promoter-specific transcription factor, Sp1. Science 1986, 234:47-52
-
(1986)
Science
, vol.234
, pp. 47-52
-
-
Briggs, M.R.1
Kadanoga, J.T.2
Bell, S.P.3
Tjian, R.4
-
42
-
-
0022541602
-
Activation of the AIDS retrovirus promoter by the cellular transcription factor, Sp1
-
Jones KA, Kadonaga JT, Luciw PA, Tjian R: Activation of the AIDS retrovirus promoter by the cellular transcription factor, Sp1. Science 1986, 232:755-759
-
(1986)
Science
, vol.232
, pp. 755-759
-
-
Jones, K.A.1
Kadonaga, J.T.2
Luciw, P.A.3
Tjian, R.4
-
43
-
-
4444376712
-
Signaling to NF-kB
-
Hayden MS, Ghosh S: Signaling to NF-kB. Genes Dev 2004, 18:2195-2224
-
(2004)
Genes Dev
, vol.18
, pp. 2195-2224
-
-
Hayden, M.S.1
Ghosh, S.2
-
44
-
-
0031925362
-
Activation of nuclear factor kappa B inflammatory bowel disease
-
Schreiber S, Nikolaus S, Hampe J: Activation of nuclear factor kappa B inflammatory bowel disease. Gut 1998, 42:477-484
-
(1998)
Gut
, vol.42
, pp. 477-484
-
-
Schreiber, S.1
Nikolaus, S.2
Hampe, J.3
-
45
-
-
33845306274
-
Proteasome-mediated degradation of IkappaBalpha and processing of p105 in Crohn disease and ulcerative colitis
-
Visekruna A, Joeris T, Seidel D, Kroesen A, Loddenkemper C, Zeitz M, Kaufmann SH, Schmidt-Ullrich R, Steinhoff U: Proteasome-mediated degradation of IkappaBalpha and processing of p105 in Crohn disease and ulcerative colitis. J Clin Invest 2006, 116:3195-3203
-
(2006)
J Clin Invest
, vol.116
, pp. 3195-3203
-
-
Visekruna, A.1
Joeris, T.2
Seidel, D.3
Kroesen, A.4
Loddenkemper, C.5
Zeitz, M.6
Kaufmann, S.H.7
Schmidt-Ullrich, R.8
Steinhoff, U.9
-
46
-
-
0028865771
-
Triggering of the human interleukin-6 gene by interferon-gamma and tumor necrosis factor-alpha in monocytic cells involves cooperation between interferon regulatory factor-1, NF kappa B, and Sp1 transcription factors
-
Sancéau J, Kaisho T, Hirano T, Wietzerbin J: Triggering of the human interleukin-6 gene by interferon-gamma and tumor necrosis factor-alpha in monocytic cells involves cooperation between interferon regulatory factor-1, NF kappa B, and Sp1 transcription factors. J Biol Chem 1995, 270:27920-27931
-
(1995)
J Biol Chem
, vol.270
, pp. 27920-27931
-
-
Sancéau, J.1
Kaisho, T.2
Hirano, T.3
Wietzerbin, J.4
-
47
-
-
0031935038
-
Functional interference of Sp1 and NF-kappaB through the same DNA binding site
-
Hirano F, Tanaka H, Hirano Y, Hiramoto M, Handa H, Makino I, Scheidereit C: Functional interference of Sp1 and NF-kappaB through the same DNA binding site. Mol Cell Biol 1998, 18:1266-1274
-
(1998)
Mol Cell Biol
, vol.18
, pp. 1266-1274
-
-
Hirano, F.1
Tanaka, H.2
Hirano, Y.3
Hiramoto, M.4
Handa, H.5
Makino, I.6
Scheidereit, C.7
-
48
-
-
33751094572
-
Identification of a hydrogen peroxide-induced PP1-JNK1-Sp1 signaling pathway for gene regulation
-
Chu S, Ferro TJ: Identification of a hydrogen peroxide-induced PP1-JNK1-Sp1 signaling pathway for gene regulation. Am J Physiol 2006, 291:L983-L992
-
(2006)
Am J Physiol
, vol.291
-
-
Chu, S.1
Ferro, T.J.2
-
49
-
-
0025144511
-
Increased expression and DNA-binding activity of transcription factor Sp1 in doxorubicin-resistant HL-60 leukemia cells
-
Borellini F, Aquino A, Josephs SF, Glazer RI: Increased expression and DNA-binding activity of transcription factor Sp1 in doxorubicin-resistant HL-60 leukemia cells. Mol Cell Biol 1990, 10:5541-5547
-
(1990)
Mol Cell Biol
, vol.10
, pp. 5541-5547
-
-
Borellini, F.1
Aquino, A.2
Josephs, S.F.3
Glazer, R.I.4
-
50
-
-
33845632790
-
Transcriptional regulation of CD38 expression by tumor necrosis factor-alpha in human airway smooth muscle cells: Role of NF-kappaB and sensitivity to glucocorticoids
-
Kang BN, Tirumurugaan KG, Deshpande DA, Amrani Y, Panettieri RA, Walseth TF, Kannan MS: Transcriptional regulation of CD38 expression by tumor necrosis factor-alpha in human airway smooth muscle cells: role of NF-kappaB and sensitivity to glucocorticoids. FASEB J 2006, 20:1000-1002
-
(2006)
FASEB J
, vol.20
, pp. 1000-1002
-
-
Kang, B.N.1
Tirumurugaan, K.G.2
Deshpande, D.A.3
Amrani, Y.4
Panettieri, R.A.5
Walseth, T.F.6
Kannan, M.S.7
-
51
-
-
0028879819
-
Role of transcriptional activation of IκB-α in mediation of immunosuppression by glucocorticoids
-
Scheinman RI, Cogswell PC, Lofuist AK, Baldwin AS: Role of transcriptional activation of IκB-α in mediation of immunosuppression by glucocorticoids. Science 1995, 270:283-286
-
(1995)
Science
, vol.270
, pp. 283-286
-
-
Scheinman, R.I.1
Cogswell, P.C.2
Lofuist, A.K.3
Baldwin, A.S.4
-
52
-
-
0028867899
-
Immunosuppression by glucocorticoids: Inhibition of NF-κB activity through induction of IκB synthesis
-
Auphan N, DiDonato JA, Rosette C, Helmberg A, Karin M: Immunosuppression by glucocorticoids: inhibition of NF-κB activity through induction of IκB synthesis. Science 1995, 270:286-290
-
(1995)
Science
, vol.270
, pp. 286-290
-
-
Auphan, N.1
DiDonato, J.A.2
Rosette, C.3
Helmberg, A.4
Karin, M.5
-
53
-
-
0024475227
-
NF-kappa B: A pleiotropic mediator of inducible and tissue specific gene control
-
Lenardo MJ, Baltimore D: NF-kappa B: a pleiotropic mediator of inducible and tissue specific gene control. Cell 1989, 58:227-229
-
(1989)
Cell
, vol.58
, pp. 227-229
-
-
Lenardo, M.J.1
Baltimore, D.2
-
54
-
-
0024516201
-
The involvement of NF-kappa B in beta-interferon gene regulation reveals its role as widely inducible mediator of signal transduction
-
Lenardo MJ, Fan CM, Maniatis T, Baltimore D: The involvement of NF-kappa B in beta-interferon gene regulation reveals its role as widely inducible mediator of signal transduction. Cell 1989, 57:287-294
-
(1989)
Cell
, vol.57
, pp. 287-294
-
-
Lenardo, M.J.1
Fan, C.M.2
Maniatis, T.3
Baltimore, D.4
-
55
-
-
0028167846
-
Inhibition of NF-κB by sodium salicylate and aspirin
-
Kopp E, Ghosh S: Inhibition of NF-κB by sodium salicylate and aspirin. Science 1994, 265:956-959
-
(1994)
Science
, vol.265
, pp. 956-959
-
-
Kopp, E.1
Ghosh, S.2
-
56
-
-
33645312379
-
Circuitry of nuclear factor κB signaling
-
Hoffmann A, Baltimore D: Circuitry of nuclear factor κB signaling. Immunol Rev 2006, 210:171-186
-
(2006)
Immunol Rev
, vol.210
, pp. 171-186
-
-
Hoffmann, A.1
Baltimore, D.2
-
57
-
-
0027384590
-
NF-κB subunit-specific regulation of the interleukin-8 promoter
-
Kunsch C, Rosen C: NF-κB subunit-specific regulation of the interleukin-8 promoter. Mol Cell Biol 1993, 13:6137-6146
-
(1993)
Mol Cell Biol
, vol.13
, pp. 6137-6146
-
-
Kunsch, C.1
Rosen, C.2
-
58
-
-
0031897632
-
NF-κB and Rel proteins: Evolutionarily conserved mediators of immune responses
-
Ghosh S, May MJ, Kopp EB: NF-κB and Rel proteins: evolutionarily conserved mediators of immune responses. Annu Rev Immunol 1998, 16:225-260
-
(1998)
Annu Rev Immunol
, vol.16
, pp. 225-260
-
-
Ghosh, S.1
May, M.J.2
Kopp, E.B.3
-
59
-
-
0035164415
-
Toll-like receptor-mediated NF-κB activation: A phylogenetically conserved paradigm in innated immunity
-
Zhang G, Ghosh S: Toll-like receptor-mediated NF-κB activation: a phylogenetically conserved paradigm in innated immunity. J Clin Invest 2001, 107:13-19
-
(2001)
J Clin Invest
, vol.107
, pp. 13-19
-
-
Zhang, G.1
Ghosh, S.2
-
60
-
-
0032771498
-
Transcriptional activation by NF-κB requires multiple coactivators
-
Sheppard KA, Rose DW, Haque ZK, Kurokawa R, McInerney E, Westin S, Thanos D, Rosenfeld MG, Glass CK, Collins T: Transcriptional activation by NF-κB requires multiple coactivators. Mol Cell Biol 1999, 19:6367-6378
-
(1999)
Mol Cell Biol
, vol.19
, pp. 6367-6378
-
-
Sheppard, K.A.1
Rose, D.W.2
Haque, Z.K.3
Kurokawa, R.4
McInerney, E.5
Westin, S.6
Thanos, D.7
Rosenfeld, M.G.8
Glass, C.K.9
Collins, T.10
-
61
-
-
0027454228
-
Association between proto-oncoprotein Rel and TATA-binding protein mediates transcriptional activation by NF-kappa B
-
Kerr LD, Ransone LJ, Wamsley P, Schmitt MJ, Boyer TG, Zhou Q, Berk AJ, Verma IM: Association between proto-oncoprotein Rel and TATA-binding protein mediates transcriptional activation by NF-kappa B. Nature 1993, 365:412-419
-
(1993)
Nature
, vol.365
, pp. 412-419
-
-
Kerr, L.D.1
Ransone, L.J.2
Wamsley, P.3
Schmitt, M.J.4
Boyer, T.G.5
Zhou, Q.6
Berk, A.J.7
Verma, I.M.8
-
62
-
-
0030698128
-
Post-transcriptional regulation contributes to Drosophila clock gene mRNA cycling
-
So WV, Rosbash M: Post-transcriptional regulation contributes to Drosophila clock gene mRNA cycling. EMBO J 1997, 16:7146-7155
-
(1997)
EMBO J
, vol.16
, pp. 7146-7155
-
-
So, W.V.1
Rosbash, M.2
-
64
-
-
0035328527
-
Accelerated age-related CpG island methylation in ulcerative colitis
-
Issa JP, Ahuja N, Toyota M, Bronner MP, Brentnall TA: Accelerated age-related CpG island methylation in ulcerative colitis. Cancer Res 2001, 61:3573-3577
-
(2001)
Cancer Res
, vol.61
, pp. 3573-3577
-
-
Issa, J.P.1
Ahuja, N.2
Toyota, M.3
Bronner, M.P.4
Brentnall, T.A.5
-
65
-
-
0032148387
-
Hypermethylation of the p16INK4a promoter in colectomy specimens of patients with long-standing and extensive ulcerative colitis
-
Hsieh CJ, Klump B, Holzmann K, Borchard F, Gregor M, Porschen R: Hypermethylation of the p16INK4a promoter in colectomy specimens of patients with long-standing and extensive ulcerative colitis. Cancer Res 1998, 58:3942-3945
-
(1998)
Cancer Res
, vol.58
, pp. 3942-3945
-
-
Hsieh, C.J.1
Klump, B.2
Holzmann, K.3
Borchard, F.4
Gregor, M.5
Porschen, R.6
-
66
-
-
0036168978
-
Hypermethylation of the p14(ARF) gene in ulcerative colitis-associated colorectal carcinogenesis
-
Sato F, Harpaz N, Shibata D, Xu Y, Yin J, Mori Y, Zou TT, Wang S, Desai K, Leytin A, Selaru FM, Abraham JM, Meltzer SJ: Hypermethylation of the p14(ARF) gene in ulcerative colitis-associated colorectal carcinogenesis. Cancer Res 2002, 62:1148-1151
-
(2002)
Cancer Res
, vol.62
, pp. 1148-1151
-
-
Sato, F.1
Harpaz, N.2
Shibata, D.3
Xu, Y.4
Yin, J.5
Mori, Y.6
Zou, T.T.7
Wang, S.8
Desai, K.9
Leytin, A.10
Selaru, F.M.11
Abraham, J.M.12
Meltzer, S.J.13
-
67
-
-
0036144048
-
DNA methylation patterns and epigenetic memory
-
Bird A: DNA methylation patterns and epigenetic memory. Genes Dev 2002, 16:6-21
-
(2002)
Genes Dev
, vol.16
, pp. 6-21
-
-
Bird, A.1
-
68
-
-
0027157651
-
Tumor necrosis factor-α induces expression of monocyte chemoattractant JE via fos and jun genes in clonal osteoblastic MC3T3-E1 cells
-
Hanazawa S, Takeshita A, Amano S, Semba T, Nirazuka T, Katoh H, Kitano S: Tumor necrosis factor-α induces expression of monocyte chemoattractant JE via fos and jun genes in clonal osteoblastic MC3T3-E1 cells. J Biol Chem 1993, 268:9526-9532
-
(1993)
J Biol Chem
, vol.268
, pp. 9526-9532
-
-
Hanazawa, S.1
Takeshita, A.2
Amano, S.3
Semba, T.4
Nirazuka, T.5
Katoh, H.6
Kitano, S.7
-
69
-
-
0041529693
-
Potentiation of tumor necrosis factor alpha-induced secreted phospholipase A2 (sPLA2)-IIA expression in mesangial cells by an autocrine loop involving sPLA2 and peroxisome proliferator-activated receptor alpha activation
-
Beck S, Lambeau G, Scholz-Pedretti K, Gelb MH, Janssen MJ, Edwards SH, Wilton DC, Pfeilschifter J, Kaszkin M: Potentiation of tumor necrosis factor alpha-induced secreted phospholipase A2 (sPLA2)-IIA expression in mesangial cells by an autocrine loop involving sPLA2 and peroxisome proliferator-activated receptor alpha activation. J Biol Chem 2003, 278:29799-29812
-
(2003)
J Biol Chem
, vol.278
, pp. 29799-29812
-
-
Beck, S.1
Lambeau, G.2
Scholz-Pedretti, K.3
Gelb, M.H.4
Janssen, M.J.5
Edwards, S.H.6
Wilton, D.C.7
Pfeilschifter, J.8
Kaszkin, M.9
-
70
-
-
0029928671
-
Tumor necrosis factor alpha: Posttranscriptional stabilization of WAF1 mRNA in p53-deficient human leukemic cells
-
Shiohara M, Akashi M, Gombart AF, Yang R, Koeffler HP: Tumor necrosis factor alpha: posttranscriptional stabilization of WAF1 mRNA in p53-deficient human leukemic cells. J Cell Physiol 1996, 166:568-576
-
(1996)
J Cell Physiol
, vol.166
, pp. 568-576
-
-
Shiohara, M.1
Akashi, M.2
Gombart, A.F.3
Yang, R.4
Koeffler, H.P.5
-
71
-
-
0034502495
-
Tumor necrosis factor alpha stimulation of human Clara cell secretory protein production by human airway epithelial cells
-
Cowan MJ, Huang X, Yao XL, Shelhamer JH: Tumor necrosis factor alpha stimulation of human Clara cell secretory protein production by human airway epithelial cells. Ann NY Acad Sci 2000, 923:193-201
-
(2000)
Ann NY Acad Sci
, vol.923
, pp. 193-201
-
-
Cowan, M.J.1
Huang, X.2
Yao, X.L.3
Shelhamer, J.H.4
-
72
-
-
0000418018
-
Tumor necrosis factor-alpha (TNFalpha) regulates the epithelial barrier in the human intestinal cell line HT-29/B6
-
Schmitz H, Fromm M, Bentzel CJ, Scholz P, Detjen K, Mankertz J, Bode H, Epple HJ, Riecken EO, Schulzke JD: Tumor necrosis factor-alpha (TNFalpha) regulates the epithelial barrier in the human intestinal cell line HT-29/B6. J Cell Sci 1999, 112:137-146
-
(1999)
J Cell Sci
, vol.112
, pp. 137-146
-
-
Schmitz, H.1
Fromm, M.2
Bentzel, C.J.3
Scholz, P.4
Detjen, K.5
Mankertz, J.6
Bode, H.7
Epple, H.J.8
Riecken, E.O.9
Schulzke, J.D.10
-
73
-
-
15244361961
-
Kinase suppressor of Ras-1 protects intestinal epithelium from cytokine-mediated apoptosis during inflammation
-
Yan F, John SK, Wilson G, Jones DS, Washington MK, Polk DB: Kinase suppressor of Ras-1 protects intestinal epithelium from cytokine-mediated apoptosis during inflammation. J Clin Invest 2004, 114:1272-1280
-
(2004)
J Clin Invest
, vol.114
, pp. 1272-1280
-
-
Yan, F.1
John, S.K.2
Wilson, G.3
Jones, D.S.4
Washington, M.K.5
Polk, D.B.6
-
74
-
-
33947318947
-
IFN-gamma and TNF-alpha decrease serotonin transporter function and expression in Caco2 cells
-
Foley KF, Pantano C, Ciolino A, Mawe GM: IFN-gamma and TNF-alpha decrease serotonin transporter function and expression in Caco2 cells. Am J Physiol 2007, 292:G779-G784
-
(2007)
Am J Physiol
, vol.292
-
-
Foley, K.F.1
Pantano, C.2
Ciolino, A.3
Mawe, G.M.4
-
75
-
-
0028804157
-
Divergent induction of apoptosis and IL-8 secretion in HT-29 cells in response to TNFa and ligation of Fas antigen
-
Abreu-Martin MT, Vidrich A, Lynch DH, Targan SR: Divergent induction of apoptosis and IL-8 secretion in HT-29 cells in response to TNFa and ligation of Fas antigen. J Immunol 1995, 155:4147-4154
-
(1995)
J Immunol
, vol.155
, pp. 4147-4154
-
-
Abreu-Martin, M.T.1
Vidrich, A.2
Lynch, D.H.3
Targan, S.R.4
-
76
-
-
42049118512
-
TNF-alpha/cycloheximide-induced apoptosis in intestinal epithelial cells requires Rac1-regulated reactive oxygen species
-
Jin S, Ray RM, Johnson LR: TNF-alpha/cycloheximide-induced apoptosis in intestinal epithelial cells requires Rac1-regulated reactive oxygen species. Am J Physiol 2008, 294:G928-G937
-
(2008)
Am J Physiol
, vol.294
-
-
Jin, S.1
Ray, R.M.2
Johnson, L.R.3
-
77
-
-
0036314767
-
Increased proliferation and apoptosis of colonic epithelial cells in dextran sulfate sodium-induced colitis in rats
-
Vetuschi A, Latella G, Sferra R, Caprilli R, Gaudio E: Increased proliferation and apoptosis of colonic epithelial cells in dextran sulfate sodium-induced colitis in rats. Dig Dis Sci 2002, 47:1447-1457
-
(2002)
Dig Dis Sci
, vol.47
, pp. 1447-1457
-
-
Vetuschi, A.1
Latella, G.2
Sferra, R.3
Caprilli, R.4
Gaudio, E.5
-
78
-
-
0037093877
-
p38 mitogen-activated protein kinase is activated and linked to TNF-α signaling in inflammatory bowel disease
-
Waetzig GH, Seegert D, Rosenstiel P, Nikolaus S, Schreiber S: p38 mitogen-activated protein kinase is activated and linked to TNF-α signaling in inflammatory bowel disease. J Immunol 2002, 168:5342-5351
-
(2002)
J Immunol
, vol.168
, pp. 5342-5351
-
-
Waetzig, G.H.1
Seegert, D.2
Rosenstiel, P.3
Nikolaus, S.4
Schreiber, S.5
-
79
-
-
34548223200
-
Dissection of a signaling pathway by which pathogen-associated molecular patterns recruit the JNK and p38 MAPKs and trigger cytokine release
-
Zhong J, Kyriakis JM: Dissection of a signaling pathway by which pathogen-associated molecular patterns recruit the JNK and p38 MAPKs and trigger cytokine release. J Biol Chem 2007, 282:24246-24254
-
(2007)
J Biol Chem
, vol.282
, pp. 24246-24254
-
-
Zhong, J.1
Kyriakis, J.M.2
|