메뉴 건너뛰기




Volumn 292, Issue 3, 2007, Pages

IFN-γ and TNF-α decrease serotonin transporter function and expression in Caco2 cells

Author keywords

Colitis; Inflammation; Inflammatory bowel disease; Interferon; SERT; Tumor necrosis factor

Indexed keywords

FLUOXETINE; GAMMA INTERFERON; INTERLEUKIN 12; MESSENGER RNA; PROSTAGLANDIN E2; S NITROSOGLUTATHIONE; SEROTONIN TRANSPORTER; TRITIUM; TUMOR NECROSIS FACTOR ALPHA;

EID: 33947318947     PISSN: 01931857     EISSN: 15221547     Source Type: Journal    
DOI: 10.1152/ajpgi.00470.2006     Document Type: Article
Times cited : (89)

References (41)
  • 1
    • 0035669353 scopus 로고    scopus 로고
    • Serotonin 1A receptors, serotonin transporter binding and serotonin transporter mRNA expression in the brainstem of depressed suicide victims
    • Arango V, Underwood MD, Boldrini M, Tamir H, Kassir SA, Hsiung S, Chen JJ, Mann JJ. Serotonin 1A receptors, serotonin transporter binding and serotonin transporter mRNA expression in the brainstem of depressed suicide victims. Neuropsychopharmacology 25: 892-903, 2001.
    • (2001) Neuropsychopharmacology , vol.25 , pp. 892-903
    • Arango, V.1    Underwood, M.D.2    Boldrini, M.3    Tamir, H.4    Kassir, S.A.5    Hsiung, S.6    Chen, J.J.7    Mann, J.J.8
  • 2
    • 0029199308 scopus 로고
    • Neurotransmitter transporters: Molecular biology, function, regulation
    • Borowsky B, Hoffman BJ. Neurotransmitter transporters: molecular biology, function, regulation. Int Rev Neurobiol 38: 139-199, 1995.
    • (1995) Int Rev Neurobiol , vol.38 , pp. 139-199
    • Borowsky, B.1    Hoffman, B.J.2
  • 3
    • 0142053206 scopus 로고    scopus 로고
    • The immunological and genetic basis of inflammatory bowel disease
    • Bouma G, Strober W. The immunological and genetic basis of inflammatory bowel disease. Nat Rev Immunol 3: 521-533, 2003.
    • (2003) Nat Rev Immunol , vol.3 , pp. 521-533
    • Bouma, G.1    Strober, W.2
  • 4
    • 0142151072 scopus 로고    scopus 로고
    • Interferon-gamma increases hPepT1-mediated uptake of di-tripeptides including the bacterial tripeptide fMLP in polarized intestinal epithelia
    • Buyse M, Charrier L, Sitaraman S, Gewirtz A, Merlin D. Interferon-gamma increases hPepT1-mediated uptake of di-tripeptides including the bacterial tripeptide fMLP in polarized intestinal epithelia. Am J Pathol 163: 1969-1977, 2003.
    • (2003) Am J Pathol , vol.163 , pp. 1969-1977
    • Buyse, M.1    Charrier, L.2    Sitaraman, S.3    Gewirtz, A.4    Merlin, D.5
  • 5
    • 0035882382 scopus 로고    scopus 로고
    • Maintenance of serotonin in the intestinal mucosa and ganglia of mice that lack the high-affinity serotonin transporter: Abnormal intestinal motility and the expression of cation transporters
    • Chen JJ, Li Z, Pan H, Murphy DL, Tamir H, Koepsell H, Gershon MD. Maintenance of serotonin in the intestinal mucosa and ganglia of mice that lack the high-affinity serotonin transporter: abnormal intestinal motility and the expression of cation transporters. J Neurosci 21: 6348-6361, 2001.
    • (2001) J Neurosci , vol.21 , pp. 6348-6361
    • Chen, J.J.1    Li, Z.2    Pan, H.3    Murphy, D.L.4    Tamir, H.5    Koepsell, H.6    Gershon, M.D.7
  • 6
    • 33646711903 scopus 로고    scopus 로고
    • Effects of serotonin transporter inhibition on gastrointestinal motility and colonic sensitivity in the mouse
    • Coates MD, Johnson AC, Greenwood-Van Meerveld B, Mawe GM. Effects of serotonin transporter inhibition on gastrointestinal motility and colonic sensitivity in the mouse. Neurogastroenterol Motil 18: 464-471, 2006.
    • (2006) Neurogastroenterol Motil , vol.18 , pp. 464-471
    • Coates, M.D.1    Johnson, A.C.2    Greenwood-Van Meerveld, B.3    Mawe, G.M.4
  • 8
    • 20444419812 scopus 로고    scopus 로고
    • Differential expression of the human chloride channel genes in the trabecular meshwork under stress conditions
    • Comes N, Gasull X, Gual A, Borras T. Differential expression of the human chloride channel genes in the trabecular meshwork under stress conditions. Exp Eye Res 80: 801-813, 2005.
    • (2005) Exp Eye Res , vol.80 , pp. 801-813
    • Comes, N.1    Gasull, X.2    Gual, A.3    Borras, T.4
  • 9
    • 23244446441 scopus 로고    scopus 로고
    • Nerves, reflexes, and the enteric nervous system: Pathogenesis of the irritable bowel syndrome
    • Gershon MD. Nerves, reflexes, and the enteric nervous system: pathogenesis of the irritable bowel syndrome. J Clin Gastroenterol 39: S184-S193, 2005.
    • (2005) J Clin Gastroenterol , vol.39
    • Gershon, M.D.1
  • 10
    • 0028289118 scopus 로고
    • 5-Hydroxytryptamine and human small intestinal motility: Effect of inhibiting 5-hydroxytryptamine reuptake
    • Gorard DA, Libby GW, Farthing MJ. 5-Hydroxytryptamine and human small intestinal motility: effect of inhibiting 5-hydroxytryptamine reuptake. Gut 35: 496-500, 1994.
    • (1994) Gut , vol.35 , pp. 496-500
    • Gorard, D.A.1    Libby, G.W.2    Farthing, M.J.3
  • 11
    • 0028301413 scopus 로고
    • Influence of antidepressants on whole gut and orocaecal transit times in health and irritable bowel syndrome
    • Gorard DA, Libby GW, Farthing MJ. Influence of antidepressants on whole gut and orocaecal transit times in health and irritable bowel syndrome. Aliment Pharmacol Ther 8: 159-166, 1994.
    • (1994) Aliment Pharmacol Ther , vol.8 , pp. 159-166
    • Gorard, D.A.1    Libby, G.W.2    Farthing, M.J.3
  • 12
    • 0022067913 scopus 로고
    • Epithelial properties of human colonic carcinoma cell line Caco-2: Effect of secretagogues
    • Grasset E, Bernabeu J, Pinto M. Epithelial properties of human colonic carcinoma cell line Caco-2: effect of secretagogues. Am J Physiol Cell Physiol 248: C410-C418, 1985.
    • (1985) Am J Physiol Cell Physiol , vol.248
    • Grasset, E.1    Bernabeu, J.2    Pinto, M.3
  • 14
    • 0032081075 scopus 로고    scopus 로고
    • Expression of inducible nitric oxide synthase (iNOS) mRNA in inflamed esophageal and colonic mucosa in a pediatric population
    • Gupta SK, Fitzgerald JF, Chong SK, Croffie JM, Garcia JG. Expression of inducible nitric oxide synthase (iNOS) mRNA in inflamed esophageal and colonic mucosa in a pediatric population. Am J Gastroenterol 93: 795-798, 1998.
    • (1998) Am J Gastroenterol , vol.93 , pp. 795-798
    • Gupta, S.K.1    Fitzgerald, J.F.2    Chong, S.K.3    Croffie, J.M.4    Garcia, J.G.5
  • 15
    • 0025899352 scopus 로고
    • Iron absorption by intestinal epithelial cells: 1. CaCo2 cells cultivated in serum-free medium, on polyethyleneterephthalate microporous membranes, as an in vitro model
    • Halleux C, Schneider YJ. Iron absorption by intestinal epithelial cells: 1. CaCo2 cells cultivated in serum-free medium, on polyethyleneterephthalate microporous membranes, as an in vitro model. In Vitro Cell Dev Biol 27A: 293-302, 1991.
    • (1991) In Vitro Cell Dev Biol , vol.27 A , pp. 293-302
    • Halleux, C.1    Schneider, Y.J.2
  • 16
    • 0030875018 scopus 로고    scopus 로고
    • Expression of cyclooxygenase-2 mRNA in active inflammatory bowel disease
    • Hendel J, Nielsen OH. Expression of cyclooxygenase-2 mRNA in active inflammatory bowel disease. Am J Gastroenterol 92: 1170-1173, 1997.
    • (1997) Am J Gastroenterol , vol.92 , pp. 1170-1173
    • Hendel, J.1    Nielsen, O.H.2
  • 17
    • 0024593744 scopus 로고
    • Characterization of the human colon carcinoma cell line (Caco-2) as a model system for intestinal epithelial permeability
    • Hidalgo IJ, Raub TJ, Borchardt RT. Characterization of the human colon carcinoma cell line (Caco-2) as a model system for intestinal epithelial permeability. Gastroenterology 96: 736-749, 1989.
    • (1989) Gastroenterology , vol.96 , pp. 736-749
    • Hidalgo, I.J.1    Raub, T.J.2    Borchardt, R.T.3
  • 18
    • 2942706073 scopus 로고    scopus 로고
    • Differential TNF-signaling in chronic inflammatory disorders
    • Holtmann MH, Neurath MF. Differential TNF-signaling in chronic inflammatory disorders. Curr Mol Med 4: 439-444, 2004.
    • (2004) Curr Mol Med , vol.4 , pp. 439-444
    • Holtmann, M.H.1    Neurath, M.F.2
  • 19
    • 21744442114 scopus 로고    scopus 로고
    • Evidence for biphasic effects of protein kinase C on serotonin transporter function, endocytosis, and phosphorylation
    • Jayanthi LD, Samuvel DJ, Blakely RD, Ramamoorthy S. Evidence for biphasic effects of protein kinase C on serotonin transporter function, endocytosis, and phosphorylation. Mol Pharmacol 67: 2077-2087, 2005.
    • (2005) Mol Pharmacol , vol.67 , pp. 2077-2087
    • Jayanthi, L.D.1    Samuvel, D.J.2    Blakely, R.D.3    Ramamoorthy, S.4
  • 23
    • 1942534113 scopus 로고    scopus 로고
    • Decreased availability of intestinal dopamine in transmural colitis may relate to inhibitory effects of interferon-gamma upon L-DOPA uptake
    • Magro F, Fraga S, Ribeiro T, Soares-da-Silva P. Decreased availability of intestinal dopamine in transmural colitis may relate to inhibitory effects of interferon-gamma upon L-DOPA uptake. Acta Physiol Scand 180: 379-386, 2004.
    • (2004) Acta Physiol Scand , vol.180 , pp. 379-386
    • Magro, F.1    Fraga, S.2    Ribeiro, T.3    Soares-da-Silva, P.4
  • 24
    • 0038002954 scopus 로고    scopus 로고
    • Uptake of serotonin at the apical and basolateral membranes of human intestinal epithelial (Caco-2) cells occurs through the neuronal serotonin transporter (SERT)
    • Martel F, Monteiro R, Lemos C. Uptake of serotonin at the apical and basolateral membranes of human intestinal epithelial (Caco-2) cells occurs through the neuronal serotonin transporter (SERT). J Pharmacol Exp Ther 306: 355-362, 2003.
    • (2003) J Pharmacol Exp Ther , vol.306 , pp. 355-362
    • Martel, F.1    Monteiro, R.2    Lemos, C.3
  • 25
    • 33646870356 scopus 로고    scopus 로고
    • Review article: Intestinal serotonin signalling in irritable bowel syndrome
    • Mawe GM, Coates MD, Moses PL. Review article: Intestinal serotonin signalling in irritable bowel syndrome. Aliment Pharmacol Ther 23: 1067-1076, 2006.
    • (2006) Aliment Pharmacol Ther , vol.23 , pp. 1067-1076
    • Mawe, G.M.1    Coates, M.D.2    Moses, P.L.3
  • 27
    • 0031767833 scopus 로고    scopus 로고
    • Interleukin 12 and Th1 responses in inflammatory bowel disease
    • Pallone F, Monteleone G. Interleukin 12 and Th1 responses in inflammatory bowel disease. Gut 43: 735-736, 1998.
    • (1998) Gut , vol.43 , pp. 735-736
    • Pallone, F.1    Monteleone, G.2
  • 28
    • 9644262469 scopus 로고    scopus 로고
    • Interferons, interferon-like cytokines, and their receptors
    • Pestka S, Krause CD, Walter MR. Interferons, interferon-like cytokines, and their receptors. Immunol Rev 202: 8-32, 2004.
    • (2004) Immunol Rev , vol.202 , pp. 8-32
    • Pestka, S.1    Krause, C.D.2    Walter, M.R.3
  • 29
    • 27644441960 scopus 로고    scopus 로고
    • Role of tumor necrosis factor receptors in an animal model of acute colitis
    • Rojas-Cartagena C, Flores I, Appleyard CB. Role of tumor necrosis factor receptors in an animal model of acute colitis. Cytokine 32: 85-93, 2005.
    • (2005) Cytokine , vol.32 , pp. 85-93
    • Rojas-Cartagena, C.1    Flores, I.2    Appleyard, C.B.3
  • 30
    • 0029066878 scopus 로고
    • Role of bile salt-dependent cholesteryl ester hydrolase in the uptake of micellar cholesterol by intestinal cells
    • Shamir R, Johnson WJ, Zolfaghari R, Lee HS, Fisher EA. Role of bile salt-dependent cholesteryl ester hydrolase in the uptake of micellar cholesterol by intestinal cells. Biochemistry 34: 6351-6358, 1995.
    • (1995) Biochemistry , vol.34 , pp. 6351-6358
    • Shamir, R.1    Johnson, W.J.2    Zolfaghari, R.3    Lee, H.S.4    Fisher, E.A.5
  • 31
    • 0029976338 scopus 로고    scopus 로고
    • Proliferation and differentiation of a human colon cancer cell line (CaCo2) is associated with significant changes in the expression and secretion of insulin-like growth factor (IGF) IGF-II and IGF binding protein-4: Role of IGF-II
    • Singh P, Dai B, Yallampalli U, Lu X, Schroy PC. Proliferation and differentiation of a human colon cancer cell line (CaCo2) is associated with significant changes in the expression and secretion of insulin-like growth factor (IGF) IGF-II and IGF binding protein-4: role of IGF-II. Endocrinology 137: 1764-1774, 1996.
    • (1996) Endocrinology , vol.137 , pp. 1764-1774
    • Singh, P.1    Dai, B.2    Yallampalli, U.3    Lu, X.4    Schroy, P.C.5
  • 32
    • 0033051316 scopus 로고    scopus 로고
    • Adverse reactions of selective serotonin reuptake inhibitors: Reports from a spontaneous reporting system
    • Spigset O. Adverse reactions of selective serotonin reuptake inhibitors: reports from a spontaneous reporting system. Drug Saf 20: 277-287, 1999.
    • (1999) Drug Saf , vol.20 , pp. 277-287
    • Spigset, O.1
  • 35
    • 0038777235 scopus 로고    scopus 로고
    • Genetic polymorphisms of serotonin and dopamine transporters in mental disorders
    • Ueno S. Genetic polymorphisms of serotonin and dopamine transporters in mental disorders. J Med Invest 50: 25-31, 2003.
    • (2003) J Med Invest , vol.50 , pp. 25-31
    • Ueno, S.1
  • 36
    • 0029885161 scopus 로고    scopus 로고
    • Localization and function of a 5-HT transporter in crypt epithelia of the gastrointestinal tract
    • Wade PR, Chen J, Jaffe B, Kassem IS, Blakely RD, Gershon MD. Localization and function of a 5-HT transporter in crypt epithelia of the gastrointestinal tract. J Neurosci 16: 2352-2364, 1996.
    • (1996) J Neurosci , vol.16 , pp. 2352-2364
    • Wade, P.R.1    Chen, J.2    Jaffe, B.3    Kassem, I.S.4    Blakely, R.D.5    Gershon, M.D.6
  • 37
    • 16244410786 scopus 로고    scopus 로고
    • Tumor necrosis factor family members and inflammatory bowel disease
    • Wang J, Fu YX. Tumor necrosis factor family members and inflammatory bowel disease. Immunol Rev 204: 144-155, 2005.
    • (2005) Immunol Rev , vol.204 , pp. 144-155
    • Wang, J.1    Fu, Y.X.2
  • 38
    • 0034252678 scopus 로고    scopus 로고
    • Serotonin transporter polymorphism and response to SSRIs in major depression and relevance to anxiety disorders and substance abuse
    • Weizman A, Weizman R. Serotonin transporter polymorphism and response to SSRIs in major depression and relevance to anxiety disorders and substance abuse. Pharmacogenomics 1: 335-341, 2000.
    • (2000) Pharmacogenomics , vol.1 , pp. 335-341
    • Weizman, A.1    Weizman, R.2
  • 39
    • 28644450976 scopus 로고    scopus 로고
    • Enterochromaffin cell hyperplasia and decreased serotonin transporter in a mouse model of postinfectious bowel dysfunction
    • Wheatcroft J, Wakelin D, Smith A, Mahoney CR, Mawe G, Spiller R. Enterochromaffin cell hyperplasia and decreased serotonin transporter in a mouse model of postinfectious bowel dysfunction. Neurogastroenterol Motil 17: 863-870, 2005.
    • (2005) Neurogastroenterol Motil , vol.17 , pp. 863-870
    • Wheatcroft, J.1    Wakelin, D.2    Smith, A.3    Mahoney, C.R.4    Mawe, G.5    Spiller, R.6
  • 40
    • 33748808678 scopus 로고    scopus 로고
    • The proinflammatory cytokines interleukin-1beta and tumor necrosis factor-alpha activate serotonin transporters
    • Zhu CB, Blakely RD, Hewlett WA. The proinflammatory cytokines interleukin-1beta and tumor necrosis factor-alpha activate serotonin transporters. Neuropsychopharmacology 31: 2121-2131, 2006.
    • (2006) Neuropsychopharmacology , vol.31 , pp. 2121-2131
    • Zhu, C.B.1    Blakely, R.D.2    Hewlett, W.A.3
  • 41
    • 2442650231 scopus 로고    scopus 로고
    • Adenosine receptor, protein kinase G, and p38 mitogen-activated protein kinase-dependent upregulation of serotonin transporters involves both transporter trafficking and activation
    • Zhu CB, Hewlett WA, Feoktistov I, Biaggioni I, Blakely RD. Adenosine receptor, protein kinase G, and p38 mitogen-activated protein kinase-dependent upregulation of serotonin transporters involves both transporter trafficking and activation. Mol Pharmacol 65: 1462-1474, 2004.
    • (2004) Mol Pharmacol , vol.65 , pp. 1462-1474
    • Zhu, C.B.1    Hewlett, W.A.2    Feoktistov, I.3    Biaggioni, I.4    Blakely, R.D.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.