Transcriptional cascade from Math1 to Mbh1 and Mbh2 is required for cerebellar granule cell differentiation

Developmental Biology

Volumn 322, Issue 2, 2008, Pages 345-354

  Kawauchi, Daisuke ^a   Saito, Tetsuichiro ^a  

^a CHIBA UNIVERSITY   (Japan)

Author keywords

Basic helix loop helix; Cerebellar granule cells; Homeobox; In vivo electroporation; Math1; Mbh1; Mbh2; Ptf1a; Purkinje cells

Indexed keywords

HOMEODOMAIN PROTEIN; OLIGODENDROCYTE TRANSCRIPTION FACTOR 2; PROTEIN MATH 1; PROTEIN MBH 1; PROTEIN MBH 2; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL DIFFERENTIATION; CEREBELLUM CORTEX; CHROMATIN IMMUNOPRECIPITATION; CONTROLLED STUDY; ELECTROPORATION; EMBRYO; GENE TRANSFER; IN VIVO STUDY; MOUSE; NERVE CELL; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN EXPRESSION;

MAMMALIA;

EID: 53049108148     PISSN: 00121606     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ydbio.2008.08.005     Document Type: Article

References (40)

1. Akazawa C., Ishibashi M., Shimizu C., Nakanishi S., and Kageyama R. A mammalian helix-loop-helix factor structurally related to the product of Drosophila proneural gene atonal is a positive transcriptional regulator expressed in the developing nervous system. J. Biol. Chem. 270 (1995) 8730-8738
2. Altman J., and Bayer S.A. Embryonic development of the rat cerebellum. I. Delineation of the cerebellar primordium and early cell movements. J. Comp. Neurol. 231 (1985) 1-26
3. Ben-Arie N., Bellen H.J., Armstrong D.L., McCall A.E., Gordadze P.R., Guo Q., Matzuk M.M., and Zoghbi H.Y. Math1 is essential for genesis of cerebellar granule neurons. Nature 390 (1997) 169-172
4. Bertrand N., Castro D.S., and Guillemot F. Proneural genes and the specification of neural cell types. Nat. Rev. Neurosci. 3 (2002) 517-530
5. Carninci P., et al. The transcriptional landscape of the mammalian genome. Science 309 (2005) 1559-1563
6. Caspary T., and Anderson K.V. Patterning cell types in the dorsal spinal cord: what the mouse mutants say. Nat. Rev. Neurosci. 4 (2003) 289-297
7. Dodd J., Morton S.B., Karagogeos D., Yamamoto M., and Jessell T.M. Spatial regulation of axonal glycoprotein expression on subsets of embryonic spinal neurons. Neuron 1 (1988) 105-116
8. Engelkamp D., Rashbass P., Seawright A., and van Heyningen V. Role of Pax6 in development of the cerebellar system. Development 126 (1999) 3585-3596
9. Englund C., Kowalczyk T., Daza R.A., Dagan A., Lau C., Rose M.F., and Hevner R.F. Unipolar brush cells of the cerebellum are produced in the rhombic lip and migrate through developing white matter. J. Neurosci. 26 (2006) 9184-9195
10. Fiez J.A. Cerebellar contributions to cognition. Neuron 16 (1996) 13-15
11. Fink A.J., Englund C., Daza R.A., Pham D., Lau C., Nivison M., Kowalczyk T., and Hevner R.F. Development of the deep cerebellar nuclei: transcription factors and cell migration from the rhombic lip. J. Neurosci. 26 (2006) 3066-3076
12. Gao J.H., Parsons L.M., Bower J.M., Xiong J., Li J., and Fox P.T. Cerebellum implicated in sensory acquisition and discrimination rather than motor control. Science 272 (1996) 482-483
13. Gazit R., Krizhanovsky V., and Ben-Arie N. Math1 controls cerebellar granule cell differentiation by regulating multiple components of the Notch signaling pathway. Development 131 (2004) 903-913
14. Goldowitz D., and Hamre K. The cells and molecules that make a cerebellum. Trends Neurosci. 21 (1998) 375-382
15. Gordon N. The cerebellum and cognition. Eur. J. Paediatr. Neurol. 11 (2007) 232-234
16. Gowan K., Helms A.W., Hunsaker T.L., Collisson T., Ebert P.J., Odom R., and Johnson J.E. Crossinhibitory activities of Ngn1 and Math1 allow specification of distinct dorsal interneurons. Neuron 31 (2001) 219-232
17. Guillemot F. Spatial and temporal specification of neural fates by transcription factor codes. Development 134 (2007) 3771-3780
18. Hatten M.E. Central nervous system neuronal migration. Annu. Rev. Neurosci. 22 (1999) 511-539
19. Helms A.W., and Johnson J.E. Progenitors of dorsal commissural interneurons are defined by MATH1 expression. Development 125 (1998) 919-928
20. Higashijima S., Michiue T., Emori Y., and Saigo K. Subtype determination of Drosophila embryonic external sensory organs by redundant homeo box genes BarH1 and BarH2. Genes Dev. 6 (1992) 1005-1018
21. Hori K., Cholewa-Waclaw J., Nakada Y., Glasgow S.M., Masui T., Henke R.M., Wildner H., Martarelli B., Beres T.M., Epstein J.A., Magnuson M.A., Macdonald R.J., Birchmeier C., and Johnson J.E. A nonclassical bHLH Rbpj transcription factor complex is required for specification of GABAergic neurons independent of Notch signaling. Genes Dev. 22 (2008) 166-178
22. Hoshino M., Nakamura S., Mori K., Kawauchi T., Terao M., Nishimura Y.V., Fukuda A., Fuse T., Matsuo N., Sone M., Watanabe M., Bito H., Terashima T., Wright C.V., Kawaguchi Y., Nakao K., and Nabeshima Y. Ptf1a, a bHLH transcriptional gene, defines GABAergic neuronal fates in cerebellum. Neuron 47 (2005) 201-213
23. Kawauchi D., Taniguchi H., Watanabe H., Saito T., and Murakami F. Direct visualization of nucleogenesis by precerebellar neurons: involvement of ventricle-directed, radial fibre-associated migration. Development 133 (2006) 1113-1123
24. Lee S.K., and Pfaff S.L. Synchronization of neurogenesis and motor neuron specification by direct coupling of bHLH and homeodomain transcription factors. Neuron 38 (2003) 731-745
25. Li S., Qiu F., Xu A., Price S.M., and Xiang M. Barhl1 regulates migration and survival of cerebellar granule cells by controlling expression of the neurotrophin-3 gene. J. Neurosci. 24 (2004) 3104-3114
26. Lim J., and Choi K.-W. Induction and autoregulation of the anti-proneural gene Bar during retinal neurogenesis in Drosophilla. Development 131 (2004) 5573-5580
27. Machold R., and Fishell G. Math1 is expressed in temporally discrete pools of cerebellar rhombic-lip neural progenitors. Neuron 48 (2005) 17-24
28. Maricich S.M., and Herrup K. Pax-2 expression defines a subset of GABAergic interneurons and their precursors in the developing murine cerebellum. J. Neurobiol. 41 (1999) 281-294
29. Morales D., and Hatten M.E. Molecular markers of neuronal progenitors in the embryonic cerebellar anlage. J. Neurosci. 26 (2006) 12226-12236
30. Pascual M., Abasolo I., Mingorance-Le Meur A., Martinez A., Del Rio J.A., Wright C.V., Real F.X., and Soriano E. Cerebellar GABAergic progenitors adopt an external granule cell-like phenotype in the absence of Ptf1a transcription factor expression. Proc. Natl. Acad. Sci. U S A. 104 (2007) 5193-5198
31. Saba R., Nakatsuji N., and Saito T. Mammalian BarH1 confers commissural neuron identity on dorsal cells in the spinal cord. J. Neurosci. 23 (2003) 1987-1991
32. Saba R., Johnson J.E., and Saito T. Commissural neuron identity is specified by a homeodomain protein, Mbh1, that is directly downstream of Math1. Development 132 (2005) 2147-2155
33. Saito T. In vivo electroporation in the embryonic mouse central nervous system. Nat. Protoc. 1 (2006) 1552-1558
34. Saito T., and Nakatsuji N. Efficient gene transfer into the embryonic mouse brain using in vivo electroporation. Dev. Biol. 240 (2001) 237-246
35. Saito T., Sawamoto K., Okano H., Anderson D.J., and Mikoshiba K. Mammalian BarH homologue is a potential regulator of neural bHLH genes. Dev. Biol. 199 (1998) 216-225
36. Saito T., Hama T., Saba R., and Nakatsuji N. Mammalian Bar-class homeobox genes. Soc. Neurosci. Abstr. 26 (2000) 600.21
37. Sotelo C. Cellular and genetic regulation of the development of the cerebellar system. Prog. Neurobiol. 72 (2004) 295-339
38. Wang V.Y., Rose M.F., and Zoghbi H.Y. Math1 expression redefines the rhombic lip derivatives and reveals novel lineages within the brainstem and cerebellum. Neuron 48 (2005) 31-43
39. Yamada M., Terao M., Terashima T., Fujiyama T., Kawaguchi Y., Nabeshima Y., and Hoshino M. Origin of climbing fiber neurons and their developmental dependence on Ptf1a. J. Neurosci. 27 (2007) 10924-10934
40. Zhao Y., Kwan K.M., Mailloux C.M., Lee W.K., Grinberg A., Wurst W., Behringer R.R., and Westphal H. LIM-homeodomain proteins Lhx1 and Lhx5, and their cofactor Ldb1, control Purkinje cell differentiation in the developing cerebellum. Proc. Natl. Acad. Sci. U S A. 104 (2007) 13182-13186