Cerebellum implicated in sensory acquisition and discrimination rather than motor control

Science

Volumn 272, Issue 5261, 1996, Pages 545-547

  Gao, Jia Hong ^a   Parsons, Lawrence M ^a   Bower, James M ^b   Xiong, Jinhu ^a   Li, Jinqi ^a   Fox, Peter T ^a  

^a UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT SAN ANTONIO   (United States)

^b CALIFORNIA INSTITUTE OF TECHNOLOGY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; CEREBELLUM; COGNITION; DENTATE NUCLEUS; HUMAN; HUMAN EXPERIMENT; HYPOTHESIS; MOTOR CONTROL; NORMAL HUMAN; NUCLEAR MAGNETIC RESONANCE; PRIORITY JOURNAL; SENSORY STIMULATION; TACTILE DISCRIMINATION;

EID: 0029887817     PISSN: 00368075     EISSN: None     Source Type: Journal    
DOI: 10.1126/science.272.5261.545     Document Type: Article

References (43)

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28. Participants in the CS and CD tasks were males, ages 32 to 44 (mean, 38). Five members of this group and a female (age 30) did the GO and GOD tasks. All participants gave informed consent and practiced each task for 10 min. In one session, they performed three cycles of rest control, CS, and CD; in another, they performed three cycles of rest control, GO, and GOD.
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30. In the two grasping tasks, each (unrestrained) hand was enclosed in its own tightly woven cotton sock; each sock contained an identical set of four different stimuli. Each stimulus was a smooth wooden sphere 2 5 cm in diameter; the stimuli were differentiated by one, two, or three additional planar surfaces. In the GO task, participants reached and grasped, in pincer fashion, a stimulus at random and then raised and dropped it. This sequence was repeated continuously and was performed independently by each hand In the GOD task, participants grasped a stimulus with the left hand, felt its shape while using the right hand to grasp and feel another stimulus, and noticed whether the two objects were identical in shape. If the objects were different, the object in the right hand was dropped and another object was grasped and compared with the object in the left hand. If the objects matched, participants released both stimuli and immediately began a new cycle, using the opposite hand to grasp the reference object.
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43. We thank W. Greenough, S.-G. Kim, R Swain, W. T. Thach, and L. Ungerleider for comments on an earlier version of this report. Supported by an EJLB Foundation grant and National Institute of Mental Health grants P20 DA52176-01 and MH/DA52145 (Human Brain Project).