Absence of association between SNPs in the promoter region of the insulin-like growth factor 1 (IGF-1) gene and longevity in the Han Chinese population

Experimental Gerontology

Volumn 43, Issue 10, 2008, Pages 962-965

  Xie, Liang ^a,b,c   Gong, Yuan ying ^a,c   Lian, Shi gang ^d   Yang, Juan ^d   Yang, Ya ^a   Gao, Shou jun ^e   Xu, Liang you ^e   Zhang, Ya ping ^a,b  

^a KUNMING INSTITUTE OF ZOOLOGY   (China)

^b YUNNAN UNIVERSITY   (China)

^c UNIVERSITY OF CHINESE ACADEMY OF SCIENCES   (China)

^d Dujiangyan People's Hospital   (China)

^e Dujiangyan Longevity Research Centre   (China)

Author keywords

Association study; Han Chinese population; IGF 1; Longevity; SNPs

Indexed keywords

SOMATOMEDIN C;

AGED; ALLELE; ARTICLE; BASE PAIRING; CHINA; CONTROLLED STUDY; FEMALE; GENE LINKAGE DISEQUILIBRIUM; GENE SEQUENCE; GENOTYPE; HAPLOTYPE; HUMAN; LONGEVITY; MALE; POPULATION RESEARCH; PRIORITY JOURNAL; PROMOTER REGION; SINGLE NUCLEOTIDE POLYMORPHISM; TRANSCRIPTION INITIATION SITE;

ADULT; AGED; AGED, 80 AND OVER; ALLELES; CHINA; FEMALE; GENOTYPE; HUMANS; INSULIN-LIKE GROWTH FACTOR I; LINKAGE DISEQUILIBRIUM; LONGEVITY; MALE; MIDDLE AGED; POLYMORPHISM, SINGLE NUCLEOTIDE; PROMOTER REGIONS, GENETIC; SIGNAL TRANSDUCTION;

EID: 53049092580     PISSN: 05315565     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.exger.2008.08.004     Document Type: Article

References (26)

1. Barrett J.C., Fry B., Maller J., and Daly M.J. Haploview: analysis and visualization of LD and haplotype maps. Bioinformatics 21 (2005) 263-265
2. Bartke A. Impact of reduced insulin-like growth factor-1/insulin signaling on aging in mammals: novel findings. Aging Cell 7 (2008) 285-290
3. Bonafe M., Barbi C., Storci G., Salvioli S., Capri M., Olivieri F., Valensin S., Monti D., Gonos E.S., De Benedictis G., and Franceschi C. What studies on human longevity tell us about the risk for cancer in the oldest old: data and hypotheses on the genetics and immunology of centenarians?. Exp. Gerontol. 37 (2002) 1263-1271
4. Bonafe M., Barbieri M., Marchegiani F., Olivieri F., Ragno E., Giampieri C., Mugianesi E., Centurelli M., Franceschi C., and Paolisso G. Polymorphic variants of insulin-like growth factor I (IGF-I) receptor and phosphoinositide 3-kinase genes affect IGF-I plasma levels and human longevity: cues for an evolutionarily conserved mechanism of life span control. J. Clin. Endocrinol. Metab. 88 (2003) 3299-3304
5. Campisi J. Cancer and ageing: rival demons?. Nat. Rev. Cancer 3 (2003) 339-349
6. Canzian F., McKay J.D., Cleveland R.J., Dossus L., Biessy C., Rinaldi S., Landi S., Boillot C., Monnier S., Chajes V., Clavel-Chapelon F., Tehard B., Chang-Claude J., Linseisen J., Lahmann P.H., Pischon T., Trichopoulos D., Trichopoulou A., Zilis D., Palli D., Tumino R., Vineis P., Berrino F., Bueno-de-Mesquita H.B., van Gils C.H., Peeters P.H., Pera G., Ardanaz E., Chirlaque M.D., Quiros J.R., Larranaga N., Martinez-Garcia C., Allen N.E., Key T.J., Bingham S.A., Khaw K.T., Slimani N., Norat T., Riboli E., and Kaaks R. Polymorphisms of genes coding for insulin-like growth factor 1 and its major binding proteins, circulating levels of IGF-I and IGFBP-3 and breast cancer risk: results from the EPIC study. Br. J. Cancer 94 (2006) 299-307
7. Cheng I., Stram D.O., Penney K.L., Pike M., Le Marchand L., Kolonel L.N., Hirschhorn J., Altshuler D., Henderson B.E., and Freedman M.L. Common genetic variation in IGF1 and prostate cancer risk in the Multiethnic Cohort. J. Natl. Cancer Inst. 98 (2006) 123-134
8. Deal C., Ma J., Wilkin F., Paquette J., Rozen F., Ge B., Hudson T., Stampfer M., and Pollak M. Novel promoter polymorphism in insulin-like growth factor-binding protein-3: correlation with serum levels and interaction with known regulators. J. Clin. Endocrinol. Metab. 86 (2001) 1274-1280
9. Holzenberger M., Dupont J., Ducos B., Leneuve P., Geloen A., Even P.C., Cervera P., and Le Bouc Y. IGF-1 receptor regulates lifespan and resistance to oxidative stress in mice. Nature 421 (2003) 182-187
10. Jansen E., Steenbergh P.H., van Schaik F.M., and Sussenbach J.S. The human IGF-I gene contains two cell type-specifically regulated promoters. Biochem. Biophys. Res. Commun. 187 (1992) 1219-1226
11. Juul A. Serum levels of insulin-like growth factor I and its binding proteins in health and disease. Growth Horm. IGF Res. 13 (2003) 113-170
12. Kenyon C. A conserved regulatory system for aging. Cell 105 (2001) 165-168
13. Kim S.W., Lajara R., and Rotwein P. Structure and function of a human insulin-like growth factor-I gene promoter. Mol. Endocrinol. 5 (1991) 1964-1972
14. Marchini J., Cardon L.R., Phillips M.S., and Donnelly P. The effects of human population structure on large genetic association studies. Nat. Genet. 36 (2004) 512-517
15. Mitchell B.D., Hsueh W.C., King T.M., Pollin T.I., Sorkin J., Agarwala R., Schaffer A.A., and Shuldiner A.R. Heritability of life span in the old order Amish. Am. J. Med. Genet. 102 (2001) 346-352
16. Patel A.V., Cheng I., Canzian F., Le Marchand L., Thun M.J., Berg C.D., Buring J., Calle E.E., Chanock S., Clavel-Chapelon F., Cox D.G., Dorronsoro M., Dossus L., Haiman C.A., Hankinson S.E., Henderson B.E., Hoover R., Hunter D.J., Kaaks R., Kolonel L.N., Kraft P., Linseisen J., Lund E., Manjer J., McCarty C., Peeters P.H., Pike M.C., Pollak M., Riboli E., Stram D.O., Tjonneland A., Travis R.C., Trichopoulos D., Tumino R., Yeager M., Ziegler R.G., and Feigelson H.S. IGF-1, IGFBP-1, and IGFBP-3 polymorphisms predict circulating IGF levels but not breast cancer risk: findings from the Breast and Prostate Cancer Cohort Consortium (BPC3). PLoS ONE 3 (2008) e2578
17. Raymond M., and Rousset F. GENEPOP (Version 12): population genetics software for exact tests and ecumenicism. J. Hered. 86 (1995) 248-249
18. Rodriguez S., Gaunt T.R., and Day I.N. Molecular genetics of human growth hormone, insulin-like growth factors and their pathways in common disease. Hum. Genet. 122 (2007) 1-21
19. Sambrook J., Fritsch E.F., and Maniatis T. Molecular Cloning: A Laboratory Manual. second ed. (1989), Cold Spring Harbor Laboratory, Cold Spring Harbor, NY
20. Stephens M., and Scheet P. Accounting for decay of linkage disequilibrium in haplotype inference and missing-data imputation. Am. J. Hum. Genet. 76 (2005) 449-462
21. Stephens M., Smith N.J., and Donnelly P. A new statistical method for haplotype reconstruction from population data. Am. J. Hum. Genet. 68 (2001) 978-989
22. Suh Y., Atzmon G., Cho M.O., Hwang D., Liu B., Leahy D.J., Barzilai N., and Cohen P. Functionally significant insulin-like growth factor I receptor mutations in centenarians. Proc. Natl. Acad. Sci. USA 105 (2008) 3438-3442
23. Tatar M., Bartke A., and Antebi A. The endocrine regulation of aging by insulin-like signals. Science 299 (2003) 1346-1351
24. van Heemst D., Beekman M., Mooijaart S.P., Heijmans B.T., Brandt B.W., Zwaan B.J., Slagboom P.E., and Westendorp R.G. Reduced insulin/IGF-1 signalling and human longevity. Aging Cell 4 (2005) 79-85
25. Wong H.L., Delellis K., Probst-Hensch N., Koh W.P., Van Den Berg D., Lee H.P., Yu M.C., and Ingles S.A. A new single nucleotide polymorphism in the insulin-like growth factor I regulatory region associates with colorectal cancer risk in Singapore Chinese. Cancer Epidemiol. Biomarkers Prev. 14 (2005) 144-151
26. Yang J., Anzo M., and Cohen P. Control of aging and longevity by IGF-I signaling. Exp. Gerontol. 40 (2005) 867-872