PEGylated conjugated linoleic acid stimulation of apoptosis via a p53-mediated signaling pathway in MCF-7 breast cancer cells

European Journal of Pharmaceutics and Biopharmaceutics

Volumn 70, Issue 2, 2008, Pages 621-626

  Seo, Ji Hye ^a   Moon, Hyun Seuk ^a,b   Kim, In Yong ^a   Guo, Ding Ding ^a   Lee, Hong Gu ^c   Choi, Yun Jaie ^a   Cho, Chong Su ^a  

^a Seoul National University   (South Korea)

^b NATIONAL INSTITUTE ON ALCOHOL ABUSE AND ALCOHOLISM   (United States)

^c Pusan National University   (South Korea)

Author keywords

Anti cancer; Conjugated linoleic acid (CLA); Nanoparticle; PEGylation; Poly (ethylene glycol) (PEG); Pro drug

Indexed keywords

CONJUGATED LINOLEIC ACID; MACROGOL; PROTEIN BAX; PROTEIN BCL 2; PROTEIN P53;

APOPTOSIS; ARTICLE; CANCER INHIBITION; CELL STRAIN MCF 7; CELL VIABILITY; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG CONJUGATION; FATTY ACID METABOLISM; FLOW CYTOMETRY; HUMAN; HUMAN CELL; REACTION ANALYSIS; SIGNAL TRANSDUCTION; TRANSMISSION ELECTRON MICROSCOPY; TUMOR SUPPRESSOR GENE; WESTERN BLOTTING;

ANIMALS; ANTINEOPLASTIC AGENTS; APOPTOSIS; BREAST NEOPLASMS; CELL CYCLE; CELL LINE, TUMOR; HALF-LIFE; HUMANS; LINOLEIC ACIDS, CONJUGATED; MICE; NIH 3T3 CELLS; POLYETHYLENE GLYCOLS; PRODRUGS; SIGNAL TRANSDUCTION; TUMOR SUPPRESSOR PROTEIN P53;

EID: 52949153571     PISSN: 09396411     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejpb.2008.05.009     Document Type: Article

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