Muscarinic, Ca++ antagonist and specific butyrylcholinesterase inhibitory activity of dried ginger extract might explain its use in dementia

Journal of Pharmacy and Pharmacology

Volumn 60, Issue 10, 2008, Pages 1375-1383

  Ghayur, Muhammad N ^a,b   Gilani, Anwarul H ^a   Ahmed, Touqeer ^a   Khalid, Asaad ^c,d   Nawaz, Sarfraz A ^d   Agbedahunsi, Joseph M ^b,e   Choudhary, Muhammad I ^d   Houghton, Peter J ^b  

^a AGA KHAN UNIVERSITY   (Pakistan)

^b KING'S COLLEGE LONDON   (United Kingdom)

^c National Center for Research Sudan   (Sudan)

^d UNIVERSITY OF KARACHI   (Pakistan)

^e OBAFEMI AWOLOWO UNIVERSITY   (Nigeria)

Author keywords

[No Author keywords available]

Indexed keywords

ATROPINE; CALCIUM ANTAGONIST; CHOLINESTERASE; GINGER EXTRACT; HEXAMETHONIUM; METHYSERGIDE; MUSCARINIC RECEPTOR; PHYSOSTIGMINE; VERAPAMIL;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CHOLINERGIC ACTIVITY; CONTROLLED STUDY; DEMENTIA; DRUG ACTIVITY; DRUG EFFECT; DRUG STRUCTURE; ENZYME ASSAY; ENZYME INHIBITION; FEMALE; GINGER; MALE; NONHUMAN; RAT;

ACETYLCHOLINE; ALZHEIMER DISEASE; ANIMALS; ATROPINE; BUTYRYLCHOLINESTERASE; CALCIUM; CALCIUM CHANNEL BLOCKERS; CATECHOLS; CHOLINESTERASE INHIBITORS; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG SYNERGISM; FATTY ALCOHOLS; GASTRIC FUNDUS; GINGER; MOLECULAR STRUCTURE; MUSCARINIC AGONISTS; PARASYMPATHOLYTICS; PHYSOSTIGMINE; PLANT EXTRACTS; RATS; RATS, SPRAGUE-DAWLEY; RHIZOME; VERAPAMIL;

EID: 52949143061     PISSN: 00223573     EISSN: None     Source Type: Journal    
DOI: 10.1211/jpp/60.10.0014     Document Type: Article

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