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Volumn 121, Issue 17, 2008, Pages 1712-1721

Critical role of △DNMT3B4/2 in regulating RASSF1A promoter-specific DNA methylation in non-small cell lung cancer

Author keywords

DNMT3B; Lung neoplasm; Methylation; SiRNA; Variants

Indexed keywords

ANTISENSE OLIGODEOXYNUCLEOTIDE; BISULFITE; DNA METHYLTRANSFERASE 3B; DNA METHYLTRANSFERASE 3B4/2; LIPOFECTAMINE; PROTEIN P16; RAS ASSOCIATION DOMAIN FAMILY PROTEIN 1A; SMALL INTERFERING RNA; UNCLASSIFIED DRUG; DNA (CYTOSINE 5) METHYLTRANSFERASE; RASSF1 PROTEIN, HUMAN; TUMOR SUPPRESSOR PROTEIN;

EID: 52949115982     PISSN: 03666999     EISSN: None     Source Type: Journal    
DOI: 10.1097/00029330-200809010-00024     Document Type: Article
Times cited : (10)

References (29)
  • 1
    • 0031860739 scopus 로고    scopus 로고
    • Cloning and characterization of a family of novel mammalian DNA (cytosine-5) methyltransferases
    • Okano M, Xie S, Li E. Cloning and characterization of a family of novel mammalian DNA (cytosine-5) methyltransferases. Nat Genet 1998; 19: 219-220.
    • (1998) Nat Genet , vol.19 , pp. 219-220
    • Okano, M.1    Xie, S.2    Li, E.3
  • 2
    • 0009836279 scopus 로고    scopus 로고
    • Ehrlich M, ed, Natick: Eaton Publishing;
    • Li E, Jaenisch R. In: Ehrlich M, ed. DNA alterations in cancer. Natick: Eaton Publishing; 2000: 351-365.
    • (2000) DNA alterations in cancer , pp. 351-365
    • Li, E.1    Jaenisch, R.2
  • 3
    • 0033615717 scopus 로고    scopus 로고
    • DNA methyltransferases Dnmt3a and Dnmt3b are essential for de novo methylation and mammalian development
    • Okano M, Bell DW, Haber DA, Li E. DNA methyltransferases Dnmt3a and Dnmt3b are essential for de novo methylation and mammalian development. Cell 1999; 99: 247-257.
    • (1999) Cell , vol.99 , pp. 247-257
    • Okano, M.1    Bell, D.W.2    Haber, D.A.3    Li, E.4
  • 4
    • 0030909592 scopus 로고    scopus 로고
    • Altered DNA methylation and genome instability: A new pathway to cancer?
    • Jones P, Gonzalgo M. Altered DNA methylation and genome instability: a new pathway to cancer? Proc Natl Acad Sci USA 1997; 94: 2103-2105.
    • (1997) Proc Natl Acad Sci USA , vol.94 , pp. 2103-2105
    • Jones, P.1    Gonzalgo, M.2
  • 5
    • 0033153303 scopus 로고    scopus 로고
    • The human DNA methyltransperases (DNMTs)1, 3a and 3b: Coordinate mRNA expression in normal tissues and overexpression in tumors
    • Robertson KD, Uzvolgyi E, Liang G, Talmadge C, Sumegi J, Gonzales FA, Jones PA. The human DNA methyltransperases (DNMTs)1, 3a and 3b: coordinate mRNA expression in normal tissues and overexpression in tumors. Nucl Aci Res 1999; 27: 2291-2298.
    • (1999) Nucl Aci Res , vol.27 , pp. 2291-2298
    • Robertson, K.D.1    Uzvolgyi, E.2    Liang, G.3    Talmadge, C.4    Sumegi, J.5    Gonzales, F.A.6    Jones, P.A.7
  • 7
    • 0037162542 scopus 로고    scopus 로고
    • Overexpression of a splice variant of DNA methyltransferase 3b, DNMT3b4, associated with DNA hypomethylation on pericentromeric satellite regions during human hepatocarcinogenesis
    • Saito Y, Kanai Y, Sakamoto M, Saito H, Ishii H, Hrohoshi S. Overexpression of a splice variant of DNA methyltransferase 3b, DNMT3b4, associated with DNA hypomethylation on pericentromeric satellite regions during human hepatocarcinogenesis. Proc Natl Acad Sci U S A 2002; 99: 10060-10065.
    • (2002) Proc Natl Acad Sci U S A , vol.99 , pp. 10060-10065
    • Saito, Y.1    Kanai, Y.2    Sakamoto, M.3    Saito, H.4    Ishii, H.5    Hrohoshi, S.6
  • 8
    • 0141995080 scopus 로고    scopus 로고
    • Expression analysis of DNA methyltransferases 1, 3A, and 3B in sporadic breast carcinomas
    • Girault I, Tozlu S, Lidereau R, Bieche I. Expression analysis of DNA methyltransferases 1, 3A, and 3B in sporadic breast carcinomas. Clin Cancer Res 2003; 9: 4415-4422.
    • (2003) Clin Cancer Res , vol.9 , pp. 4415-4422
    • Girault, I.1    Tozlu, S.2    Lidereau, R.3    Bieche, I.4
  • 9
    • 0035461346 scopus 로고    scopus 로고
    • DNA methylation status of hMLH1, p16(INK4a), and CDH1 is not associated with mRNA expression levels of DNA methyltransferase and DNA demethylase in gastric carcinomas
    • Oue N, Kuraoka K, Kuniyasu H, Yokozaki H, Wakikawa A, Matsusaki K, et al. DNA methylation status of hMLH1, p16(INK4a), and CDH1 is not associated with mRNA expression levels of DNA methyltransferase and DNA demethylase in gastric carcinomas. Oncol Rep 2001; 8: 1085-1089.
    • (2001) Oncol Rep , vol.8 , pp. 1085-1089
    • Oue, N.1    Kuraoka, K.2    Kuniyasu, H.3    Yokozaki, H.4    Wakikawa, A.5    Matsusaki, K.6
  • 10
    • 0041627372 scopus 로고    scopus 로고
    • Over-expression of DNA methyltranferases and CDKN2A gene methylation status in squamous cell carcinoma of the oral cavity
    • Yakushiji T, Uzawa K, Shibahara T, Noma H, Tanzawa H. Over-expression of DNA methyltranferases and CDKN2A gene methylation status in squamous cell carcinoma of the oral cavity. Int J Oncol 2003; 22: 1201-1207.
    • (2003) Int J Oncol , vol.22 , pp. 1201-1207
    • Yakushiji, T.1    Uzawa, K.2    Shibahara, T.3    Noma, H.4    Tanzawa, H.5
  • 11
    • 0037130479 scopus 로고    scopus 로고
    • The expression of DNA methyltransferases and methyl-CpG-binding proteins is not associated with the methylation status of p14(ARF), p16(INK4a) and RASSF1A in human lung cancer cell lines
    • Sato M, Horio Y, Sekido Y, Minna JD, Shimokata K, Hasegawa Y. The expression of DNA methyltransferases and methyl-CpG-binding proteins is not associated with the methylation status of p14(ARF), p16(INK4a) and RASSF1A in human lung cancer cell lines. Oncogene 2002; 21: 4822-4829.
    • (2002) Oncogene , vol.21 , pp. 4822-4829
    • Sato, M.1    Horio, Y.2    Sekido, Y.3    Minna, J.D.4    Shimokata, K.5    Hasegawa, Y.6
  • 12
    • 33749020195 scopus 로고    scopus 로고
    • A novel DNMT3B subfamily, DeltaDNMT3B, is the predominant form of DNMT3B in non-small cell lung cencer
    • Wang L, Wang J, Sun S, Rodriguez M, Yue P, Jang SJ, et al. A novel DNMT3B subfamily, DeltaDNMT3B, is the predominant form of DNMT3B in non-small cell lung cencer. Int J Oncol 2006; 29: 201-207.
    • (2006) Int J Oncol , vol.29 , pp. 201-207
    • Wang, L.1    Wang, J.2    Sun, S.3    Rodriguez, M.4    Yue, P.5    Jang, S.J.6
  • 13
    • 2342557977 scopus 로고    scopus 로고
    • A simple method for estimating global DNA methylation using bisulfite PCR of repetitive DNA elements
    • Yang AS, Estecio MR, Doshi K, Kondo Y, Tajara EH, Issa JP. A simple method for estimating global DNA methylation using bisulfite PCR of repetitive DNA elements. Nucleic Acids Res 2004; 32: e38.
    • (2004) Nucleic Acids Res , vol.32
    • Yang, A.S.1    Estecio, M.R.2    Doshi, K.3    Kondo, Y.4    Tajara, E.H.5    Issa, J.P.6
  • 14
    • 0033918563 scopus 로고    scopus 로고
    • Epigenetic inactivation of a RAS association domain family protein from the lung tumour suppressor locus 3p21.3
    • Dammann R, Li C, Yoon JH, Chin PL, Bates S, Pfeifer GP. Epigenetic inactivation of a RAS association domain family protein from the lung tumour suppressor locus 3p21.3. Nat Genet 2000; 25: 315-319.
    • (2000) Nat Genet , vol.25 , pp. 315-319
    • Dammann, R.1    Li, C.2    Yoon, J.H.3    Chin, P.L.4    Bates, S.5    Pfeifer, G.P.6
  • 15
  • 16
    • 0036583731 scopus 로고    scopus 로고
    • Molecular pathogenesis of lung cancer and potential translational applications
    • Minna JD, Fong K, Zochbauer-Muller S, Gazdar AF. Molecular pathogenesis of lung cancer and potential translational applications. Cancer J 2002; 8 Suppl 1: S41-S46.
    • (2002) Cancer J , vol.8 , Issue.SUPPL. 1
    • Minna, J.D.1    Fong, K.2    Zochbauer-Muller, S.3    Gazdar, A.F.4
  • 17
    • 0029011539 scopus 로고
    • 5′ CpG island methylation is associated with transcriptional silencing of the tumour suppressor p16/CDKN2/MTS1 in human cancers
    • Merlo A, Herman JG, Mao L, Lee DJ, Gabrielson E, Burger PC, et al. 5′ CpG island methylation is associated with transcriptional silencing of the tumour suppressor p16/CDKN2/MTS1 in human cancers. Nat Med 1995; 1: 686-692.
    • (1995) Nat Med , vol.1 , pp. 686-692
    • Merlo, A.1    Herman, J.G.2    Mao, L.3    Lee, D.J.4    Gabrielson, E.5    Burger, P.C.6
  • 19
  • 20
    • 0141988726 scopus 로고    scopus 로고
    • Double RNA interference of DNMT3b and DNMT1 enhances DNA demethylation and gene reactivation
    • Leu YW, Rahmatpanah F, Shi H, Wei SH, Liu JC, Yan PS, et al. Double RNA interference of DNMT3b and DNMT1 enhances DNA demethylation and gene reactivation. Cancer Res 2003; 63: 6110-6115.
    • (2003) Cancer Res , vol.63 , pp. 6110-6115
    • Leu, Y.W.1    Rahmatpanah, F.2    Shi, H.3    Wei, S.H.4    Liu, J.C.5    Yan, P.S.6
  • 21
    • 0036683055 scopus 로고    scopus 로고
    • Co-operation and communication between the human maintenance and de novo DNA methylatransferases
    • Kim GD, Ni J, Kelesoghu N, Roberts RJ, Prodham S. Co-operation and communication between the human maintenance and de novo DNA methylatransferases. EMBO J 2002; 21: 4183-4195.
    • (2002) EMBO J , vol.21 , pp. 4183-4195
    • Kim, G.D.1    Ni, J.2    Kelesoghu, N.3    Roberts, R.J.4    Prodham, S.5
  • 22
    • 0037373891 scopus 로고    scopus 로고
    • A systematic profile of DNA methylation in human cancer cell lines
    • Paz MF, Fraga W, Avila S, Guo M, Pollan M, Herman JG, et al. A systematic profile of DNA methylation in human cancer cell lines. Cancer Res 2003; 63: 1114-1121.
    • (2003) Cancer Res , vol.63 , pp. 1114-1121
    • Paz, M.F.1    Fraga, W.2    Avila, S.3    Guo, M.4    Pollan, M.5    Herman, J.G.6
  • 24
    • 0037081176 scopus 로고    scopus 로고
    • Aberrant promoter methylation of multiple genes in bronchial brush samples from former cigarette smokers
    • Soria JC, Rodriguez M, Liu DD, Lee JJ, Hong WK, Mao L. Aberrant promoter methylation of multiple genes in bronchial brush samples from former cigarette smokers. Cancer Res 2002; 62: 351-355.
    • (2002) Cancer Res , vol.62 , pp. 351-355
    • Soria, J.C.1    Rodriguez, M.2    Liu, D.D.3    Lee, J.J.4    Hong, W.K.5    Mao, L.6
  • 25
    • 0033580326 scopus 로고    scopus 로고
    • A mammalian protein with specific demethylase activity for mCpG DNA
    • Bhattacharya SK, Ramchandani S, Cervoni N, Szyf M. A mammalian protein with specific demethylase activity for mCpG DNA. Nature 1999; 397: 579-583.
    • (1999) Nature , vol.397 , pp. 579-583
    • Bhattacharya, S.K.1    Ramchandani, S.2    Cervoni, N.3    Szyf, M.4
  • 26
    • 0037183968 scopus 로고    scopus 로고
    • Promoter-specific activation and demethylation by MBD2/demethylase
    • Detich N, Bovenzi V, Szyf M. Promoter-specific activation and demethylation by MBD2/demethylase. J Biol Chem 2002; 277: 35791-35794.
    • (2002) J Biol Chem , vol.277 , pp. 35791-35794
    • Detich, N.1    Bovenzi, V.2    Szyf, M.3
  • 27
    • 0042346416 scopus 로고    scopus 로고
    • Valproate induces replication-independent active DNA demethylation
    • Detich N, Bovenzi V, Szyf M. Valproate induces replication-independent active DNA demethylation. J Biol Chem 2003; 278: 27586-27592.
    • (2003) J Biol Chem , vol.278 , pp. 27586-27592
    • Detich, N.1    Bovenzi, V.2    Szyf, M.3
  • 28
    • 0035542974 scopus 로고    scopus 로고
    • Methyl CpG-binding proteins and transcriptional repression
    • Wade PA. Methyl CpG-binding proteins and transcriptional repression. Bioessays 2001; 23: 1131-1137.
    • (2001) Bioessays , vol.23 , pp. 1131-1137
    • Wade, P.A.1
  • 29
    • 33846850155 scopus 로고    scopus 로고
    • Analysis of tissue-specific differentially. methylated regions (TDMs) in humans
    • Kitamura E, Iqarashi J, Morohashi A, Hida N, Oinuma T, Nemoto N, et al. Analysis of tissue-specific differentially. methylated regions (TDMs) in humans. Genomics 2007; 89: 326-337.
    • (2007) Genomics , vol.89 , pp. 326-337
    • Kitamura, E.1    Iqarashi, J.2    Morohashi, A.3    Hida, N.4    Oinuma, T.5    Nemoto, N.6


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