Effect of β2-adrenoceptor agonists and other cAMP-elevating agents on inflammatory gene expression in human ASM cells: A role for protein kinase A

American Journal of Physiology - Lung Cellular and Molecular Physiology

Volumn 295, Issue 3, 2008, Pages

  Kaur, Manminder ^a,b   Holden, Neil S ^a   Wilson, Sylvia M ^a   Sukkar, Maria B ^c   Chung, Kian Fan ^b   Barnes, Peter J ^b   Newton, Robert ^a   Giembycz, Mark A ^a  

^a UNIVERSITY OF CALGARY   (Canada)

^b NATIONAL HEART AND LUNG INSTITUTE   (United Kingdom)

^c UNIVERSITY OF SYDNEY   (Australia)

Author keywords

Asthma; Human airway smooth muscle cells; Inflammation; Prostaglandin

Indexed keywords

8 BROMO CYCLIC AMP; ADENOVIRUS VECTOR; BETA 2 ADRENERGIC RECEPTOR STIMULATING AGENT; CYCLIC AMP; CYCLIC AMP DEPENDENT PROTEIN KINASE; CYCLIC AMP DEPENDENT PROTEIN KINASE INHIBITOR; FORMOTEROL; FORSKOLIN; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INDOMETACIN; INTERCELLULAR ADHESION MOLECULE 1; INTERLEUKIN 1BETA; INTERLEUKIN 6; INTERLEUKIN 8; LUCIFERASE; PROSTAGLANDIN E2; PROTEIN KINASE INHIBITOR; PROTEIN PKIALPHA; ROLIPRAM; SALBUTAMOL; SALMETEROL; UNCLASSIFIED DRUG; VIRUS PROTEIN; AUTACOID; BETA 2 ADRENERGIC RECEPTOR; DRUG DERIVATIVE; IL6 PROTEIN, HUMAN; IL8 PROTEIN, HUMAN;

AIRWAY; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CONTROLLED STUDY; CYCLIC AMP BLOOD LEVEL; CYTOKINE RELEASE; DRUG FORMULATION; DRUG MECHANISM; DRUG RELEASE; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME REPRESSION; GENE EXPRESSION; GENE EXPRESSION REGULATION; GENE OVEREXPRESSION; HUMAN; HUMAN CELL; INFLAMMATION; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; REPORTER GENE; SMOOTH MUSCLE FIBER; BIOSYNTHESIS; CELL CULTURE; CYTOLOGY; DRUG EFFECT; DRUG POTENTIATION; GENETICS; METABOLISM; RESPIRATORY SYSTEM;

ALBUTEROL; CELLS, CULTURED; CYCLIC AMP; CYCLIC AMP-DEPENDENT PROTEIN KINASES; DINOPROSTONE; FORSKOLIN; GENE EXPRESSION; GRANULOCYTE-MACROPHAGE COLONY-STIMULATING FACTOR; HUMANS; INFLAMMATION MEDIATORS; INTERCELLULAR ADHESION MOLECULE-1; INTERLEUKIN-6; INTERLEUKIN-8; MYOCYTES, SMOOTH MUSCLE; RECEPTORS, ADRENERGIC, BETA-2; RESPIRATORY SYSTEM;

EID: 52649103135     PISSN: 10400605     EISSN: 15221504     Source Type: Journal    
DOI: 10.1152/ajplung.00046.2008     Document Type: Article

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