Isoproterenol induces actin depolymerization in human airway smooth muscle cells via activation of an Src kinase and GS

American Journal of Physiology - Lung Cellular and Molecular Physiology

Volumn 288, Issue 5 32-5, 2005, Pages

  Hirshman, Carol A ^a   Zhu, Defen ^a   Pertel, Thomas ^a   Panettieri, Reynold A ^b   Emala, Charles W ^a  

^a Columbia University ^*  (United States)

^b UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

4 Amino 5 (4 chlorophenyl) 7 (t butyl)pyrazolo 3,4 d pyriimidine; Geldanamycin; Phosphatidylinositol 3 kinase; Protein kinase A; Tyrosine 416

Indexed keywords

4 AMINO 7 TERT BUTYL 5 (4 CHLOROPHENYL)PYRAZOLO[3,4 D]PYRIMIDINE; CYCLIC AMP DEPENDENT PROTEIN KINASE INHIBITOR; DEOXYRIBONUCLEASE I; EPIDERMAL GROWTH FACTOR RECEPTOR; FORSKOLIN; GELDANAMYCIN; ISOPRENALINE; MITOGEN ACTIVATED PROTEIN KINASE INHIBITOR; PHOSPHATIDYLINOSITOL 3 KINASE INHIBITOR; PROSTAGLANDIN E1; PROTEIN TYROSINE KINASE; PROTEIN TYROSINE KINASE INHIBITOR; STIMULATORY GUANINE NUCLEOTIDE BINDING PROTEIN;

ACTIN FILAMENT; AIRWAY; ARTICLE; CONTROLLED STUDY; DEPOLYMERIZATION; DRUG EFFECT; ENZYME ACTIVATION; ENZYME INHIBITION; HUMAN; HUMAN CELL; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; SMOOTH MUSCLE FIBER; TRACHEA MUSCLE;

ADJUVANTS, IMMUNOLOGIC; ADRENERGIC BETA-AGONISTS; BENZOQUINONES; CELLS, CULTURED; CHOLERA TOXIN; ENZYME INHIBITORS; GTP-BINDING PROTEIN ALPHA SUBUNITS, GS; HUMANS; ISOPROTERENOL; LACTAMS, MACROCYCLIC; MYOCYTES, SMOOTH MUSCLE; PHOSPHORYLATION; QUINONES; SRC-FAMILY KINASES; TRACHEA; TYROSINE;

EID: 17444390816     PISSN: 10400605     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajplung.00463.2004     Document Type: Article

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