Amelogenin binds to both heparan sulfate and bone morphogenetic protein 2 and pharmacologically suppresses the effect of noggin

Bone

Volumn 43, Issue 2, 2008, Pages 371-376

  Saito, Kan ^a   Konishi, Ikuri ^a   Nishiguchi, Miyuki ^a   Hoshino, Tomonori ^a   Fujiwara, Taku ^a  

^a NAGASAKI UNIVERSITY GRADUATE SCHOOL OF BIOMEDICAL SCIENCES   (Japan)

Author keywords

Amelogenin; BMP; Heparan sulfate; Noggin; Osteoblast

Indexed keywords

ALKALINE PHOSPHATASE; AMELOGENIN; AMELOGENIN ANTIBODY; AMINO ACID; BONE MORPHOGENETIC PROTEIN 2; BONE MORPHOGENETIC PROTEIN 2 ANTIBODY; BONE MORPHOGENETIC PROTEIN 4 ANTIBODY; HEPARAN SULFATE; HEPARIN; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; NOGGIN; PROTEIN ANTIBODY; SMAD1 PROTEIN; SMAD5 PROTEIN; SMAD8 PROTEIN; TRANSFORMING GROWTH FACTOR BETA 1 ANTIBODY; TRANSFORMING GROWTH FACTOR BETA1; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; ANIMAL CELL; ARTICLE; BONE DEVELOPMENT; CALCIFICATION; CONTROLLED STUDY; ENAMEL; ENZYME ACTIVITY; ENZYME INHIBITION; IMPLANT; MOUSE; NONHUMAN; OSTEOBLAST; PHARMACOLOGICAL BLOCKING; POLYACRYLAMIDE GEL ELECTROPHORESIS; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; SEQUENCE ANALYSIS; SIGNAL TRANSDUCTION; TOOTH DEVELOPMENT; WESTERN BLOTTING;

EID: 52449130044     PISSN: 87563282     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bone.2008.03.029     Document Type: Article

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