Structure and function of fibroblast growth factor

Brazilian Journal of Medical and Biological Research

Volumn 29, Issue 7, 1996, Pages 835-839

  Gambrini, A G ^a   Miranda, M T M ^a   Viviani, W ^a   Oyama Jr , S ^a   Kiyota, S ^a   Toma, I N ^a  

^a UNIVERSITY OF SÃO PAULO   (Brazil)

Author keywords

fibroblast growth factor; heparan sulfate; heparin; mitogenesis; molecular modelling; synthetic peptides

Indexed keywords

FIBROBLAST GROWTH FACTOR; HEPARAN SULFATE; HEPARIN; SYNTHETIC PEPTIDE;

ARTICLE; CHEMICAL STRUCTURE; MITOGENESIS; MOLECULAR MODEL; NONHUMAN;

AMINO ACID SEQUENCE; FIBROBLAST GROWTH FACTOR 1; FIBROBLAST GROWTH FACTORS; HEPARIN; HEPARITIN SULFATE; HUMANS; MITOGENS; MITOSIS; MOLECULAR SEQUENCE DATA; PEPTIDES;

EID: 0030055877     PISSN: 0100879X     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (21)

1. Burgess WH & Maciag T (1989). The heparin-binding (fibroblast growth factor) family of proteins. Annual Review of Biochemistry, 58: 575-606.
2. Baird A & Klagsbrun M (1991). The fibroblast growth factor family. Cancer Cells, 3: 239-243.
3. Folkman J & Klagsbrun M (1987). Angiogenesis factors. Science, 235: 442-447.
4. Zhu Z, Komiya H, Chirino A, Faham S, Fox GM, Arakawa T, Hsu BT & Rees DC (1991). Three-dimensional structures of acidic and basic fibroblast growth factors. Science, 251: 90-93.
5. Pantoliano MW, Horlick RA, Springer BA, VanDyk DE, Tobery T, Wetmore DR, Lear JD, Nahapetian AJ, Bradley JD & Sisk WP (1994). Multivalent ligand-receptor binding interactions in the fibroblast growth factor system produce a cooperative growth factor and heparin mechanism for receptor dimerization. Biochemistry, 33: 10229-10248.
6. Springer BA, Pantoliano MW, Barbera FA, Gunyuzlu PL, Thompson LD, Herblin WF, Rosenfeld SA & Book GW (1994). Identification and concerted function of two receptor binding surfaces on basic fibroblast growth factor required for mitogenesis. Journal of Biological Chemistry, 269: 26879-26884.
7. Wang F, Kan M, Xu J, Yan G & McKeehan W (1995). Ligand-specific structural domains in the fibroblast growth factor receptor. Journal of Biological Chemistry, 270: 10222-10230.
8. Thompson LD, Pantoliano MW & Springer BA (1994). Energetic characterization of the basic fibroblast growth factor - heparin interaction: identification of the heparin-binding domain. Biochemistry, 33: 3831-3840.
9. Murzin AG, Lesk AM & Chothia C (1992). ß-Trefoil fold - patterns of structures and sequences in the Kunitz inhibitors, interleukins-1ß and 1α and fibroblast growth factors. Journal of Molecular Biology, 223: 531-543.
10. Gambarini AG, Miyamoto CA, Lima GA, Nader HB & Dietrich CP (1993). Mitogenic activity of acidic fibroblast growth factor is enhanced by highly sulfated oligosaccharides derived from heparin and heparan sulfate. Molecular and Cellular Biochemistry, 124: 121-129.
11. Armelin HA (1973). Pituitary extracts and steroid hormones in the control of 3T3 cell growth. Proceedings of the National Academy of Sciences, USA, 70: 2702-2706.
12. Oyama Jr S, Miranda MTM, Toma IN, Viviani W & Gambarini AG (1995). Mitogenic activity of synthetic peptides homologous to the FGF-1 sequence. Proceedings of the 14th American Peptide Symposium, P208.
13. Stewart JM & Young JD (1984). Solid Phase Peptide Synthesis. 2nd edn. Pierce Chemical Co., Rockford, IL.
14. Wong P, Hampton B, Szylobryt E, Gallagher AM & Jaye M (1995). Analysis of putative heparin-binding domains of fibroblast growth factor-1. Journal of Biological Chemistry, 270: 25805-25811.
15. Sudhalter J, Folkman J, Svahn CM, Bergendal K & D'Amore PA (1989). Importance of size, sulfation and anticoagulant activity in the potentiation of acidic fibroblast growth factor by heparin. Journal of Biological Chemistry, 264: 6892-6897.
16. 13C NMR spectroscopy. Journal of Biological Chemistry, 265: 16807-16813.
17. Turnbull JE, Fernig DG, Ke Y, Wilkinson MC & Gallagher JT (1992). Identification of the basic fibroblast growth factor binding sequence in fibroblast heparan sulfate. Journal of Biological Chemistry, 267: 10337-10341.
18. Kjellén L & Lindahl U (1991). Proteoglycans: structures and interactions. Annual Review of Biochemistry, 60: 443-475.
19. Jackson RL, Buch SJ & Cardin AD (1991). Glycosaminoglycans: molecular properties, protein interactions and role in physiological processes. Physiological Reviews, 71: 481-539.
20. Kiefer MC, Stephans JC, Crawford K, Okino K & Barr PJ (1990). Ligand-affinity cloning and structure of a cell surface heparan sulfate proteoglycan that binds basic fibroblast growth factor. Proceedings of the National Academy of Sciences, USA, 87: 6985-6989.
21. Tersariol ILS, Ferreira TMPC, Medeiros MGL, Porcionatto MA, Moraes CT, Abreu LRD, Nader HB & Dietrich CP (1994). Sequencing of heparan sulfate proteoglycans: identification of variable and constant oligosaccharide regions in eight heparan sulfate proteoglycans of different origins. Brazilian Journal of Medical and Biological Research, 27: 2097-2102.